{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T00:47:02Z","timestamp":1761094022427,"version":"build-2065373602"},"reference-count":33,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T00:00:00Z","timestamp":1761004800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathogens"],"abstract":"<jats:p>Background: In the 19th century, pulmonary tuberculosis was the leading cause of death in Europe, responsible for up to one-quarter of all mortality. Before Robert Koch\u2019s discovery of the tubercle bacillus in 1882 and the advent of effective therapies, treatment relied on rest, high-caloric diets, and sanatoria. Objectives: This study aims to reconstruct the medical biography of Dr. \u0218erban Eminovici (1841\u20131874), Romanian physician and elder brother of poet Mihai Eminescu, and to contextualize his life and death within the broader history of tuberculosis and pre-antibiotic medical practice. Methods: We conducted a historical case study using archival sources, including university registers from Erlangen, Munich, and Vienna, hospital admission records from the Charit\u00e9 Hospital in Berlin, and contemporaneous correspondence. Secondary literature on the history of tuberculosis and the Eminovici family was also reviewed. Results: Eminovici pursued medical studies across Central Europe, obtaining his doctorate in Vienna and later practicing medicine in Berlin, where he was a member of the Berliner Medizinische Gesellschaft. Despite early signs of respiratory illness, treated at spa resorts such as Gleichenberg, his condition progressed to advanced pulmonary tuberculosis with neuropsychiatric complications. Hospital records confirm his admission to the Charit\u00e9 on 10 October 1874, and his death from \u201cLungenschwindsucht\u201d (pulmonary tuberculosis) on 29 November 1874, at age 33. His trajectory illustrates both the transnational mobility of Romanian intellectual elites and the therapeutic limitations of pre-antibiotic medicine. Conclusions: The case of Dr. \u0218erban Eminovici highlights the devastating impact of tuberculosis on 19th-century intellectuals, the reliance on lifestyle-based therapies before the discovery of the tubercle bacillus, and the importance of Central European medical networks in shaping Romanian professional identities. Beyond its biographical significance, this case underscores the persistent social and cultural burden of tuberculosis in Eastern Europe.<\/jats:p>","DOI":"10.3390\/pathogens14101067","type":"journal-article","created":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T14:17:35Z","timestamp":1761056255000},"page":"1067","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Pulmonary Tuberculosis in the 19th Century: A Historical Case Study of Dr. \u0218erban Eminovici, Romanian Physician and Brother of Poet Mihai Eminescu"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1441-1751","authenticated-orcid":false,"given":"Andrei Ionut","family":"Cucu","sequence":"first","affiliation":[{"name":"Faculty of Medicine and Biological Sciences, Stefan cel Mare University of Suceava, 720229 Suceava, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catalin M.","family":"Buzduga","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Navena","family":"Widulin","sequence":"additional","affiliation":[{"name":"Berlin Museum of Medical History, Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin, Charit\u00e9platz 1, 10117 Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4376-4874","authenticated-orcid":false,"given":"Alexandru","family":"Nemtoi","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Biological Sciences, Stefan cel Mare University of Suceava, 720229 Suceava, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-2874-9227","authenticated-orcid":false,"given":"Amelian Madalin","family":"Bobu","sequence":"additional","affiliation":[{"name":"Clinical Emergency Hospital St. Spiridon, 700111 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2488-2154","authenticated-orcid":false,"given":"Claudia Florida","family":"Costea","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4708-8287","authenticated-orcid":false,"given":"Roxana","family":"Filip","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Biological Sciences, Stefan cel Mare University of Suceava, 720229 Suceava, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0891-4857","authenticated-orcid":false,"given":"Vlad","family":"Porumb","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anca Petruta","family":"Morosan","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9112-7039","authenticated-orcid":false,"given":"Alexandru","family":"Carauleanu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anca","family":"Sava","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2859-2066","authenticated-orcid":false,"given":"Elena","family":"Porumb-Andrese","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0646-985X","authenticated-orcid":false,"given":"Emilia","family":"Patrascanu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camelia","family":"Tamas","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6562-1017","authenticated-orcid":false,"given":"Andreas G.","family":"Nerlich","sequence":"additional","affiliation":[{"name":"Institute of Legal Medicine, Department of Forensic Histology, Paleopathology and Mummy Research, Ludwig-Maximilians-University, 80336 Munich, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,10,21]]},"reference":[{"key":"ref_1","first-page":"36","article-title":"History of Tuberculosis. Part 2\u2014The Sanatoria and the Discoveries of the Tubercle Bacillus","volume":"22","author":"Frith","year":"2014","journal-title":"J. Mil. 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