{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T22:42:23Z","timestamp":1768862543985,"version":"3.49.0"},"reference-count":30,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T00:00:00Z","timestamp":1768780800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathogens"],"abstract":"<jats:p>Neurocysticercosis (NCC) remains a major public health problem in endemic countries. Clinical manifestations and therapeutic strategies vary depending on the location of the parasite. While the benefits of cysticidal treatment are well established for parenchymal and subarachnoid NCC, the optimal management of intraventricular NCC (IVNCC) remains controversial. We conducted a retrospective study of 51 patients: 37 (72.54%) received cysticidal treatment as initial therapy and 14 (27.45%) underwent neurosurgical intervention. Although six months after treatment, the proportion of patients with inactive disease was higher in the surgical group, no significant difference was observed after one year. Patients in both groups showed significant improvement in functionality as measured by the Karnofsky Index (KI), with no significant difference between groups. These results are consistent with cysticidal treatment being a valid therapeutic option for IVNCC, with the choice of management largely determined by the available medical infrastructure and the degree of specialization of healthcare personnel.<\/jats:p>","DOI":"10.3390\/pathogens15010108","type":"journal-article","created":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T09:57:02Z","timestamp":1768816622000},"page":"108","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparison of Effectiveness Between Cysticidal and Surgical Treatments in Patients with Intraventricular Neurocysticercosis: A Single-Center Experience"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-0581-3517","authenticated-orcid":false,"given":"Alex Aar\u00f3n","family":"Agallo-Mart\u00ednez","sequence":"first","affiliation":[{"name":"Unidad de Neuroinflamaci\u00f3n, Departamento de Medicina Gen\u00f3mica y Toxicolog\u00eda Ambiental, Instituto de Investigaci\u00f3n Biom\u00e9dicas, Universidad Nacional Aut\u00f3noma de M\u00e9xico, Instituto Nacional de Neurolog\u00eda y Neurocirug\u00eda Manuel Velasco Su\u00e1rez (INNN-MVS), M\u00e9xico City 14269, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebeca","family":"Ram\u00edrez-Bustamante","sequence":"additional","affiliation":[{"name":"Unidad de Neuroinflamaci\u00f3n, Departamento de Medicina Gen\u00f3mica y Toxicolog\u00eda Ambiental, Instituto de Investigaci\u00f3n Biom\u00e9dicas, Universidad Nacional Aut\u00f3noma de M\u00e9xico, Instituto Nacional de Neurolog\u00eda y Neurocirug\u00eda Manuel Velasco Su\u00e1rez (INNN-MVS), M\u00e9xico City 14269, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-9700-0739","authenticated-orcid":false,"given":"Polet","family":"Ju\u00e1rez-Ort\u00edz","sequence":"additional","affiliation":[{"name":"Unidad de Neuroinflamaci\u00f3n, Departamento de Medicina Gen\u00f3mica y Toxicolog\u00eda Ambiental, Instituto de Investigaci\u00f3n Biom\u00e9dicas, Universidad Nacional Aut\u00f3noma de M\u00e9xico, Instituto Nacional de Neurolog\u00eda y Neurocirug\u00eda Manuel Velasco Su\u00e1rez (INNN-MVS), M\u00e9xico City 14269, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ximena","family":"Guti\u00e9rrez-Bonilla","sequence":"additional","affiliation":[{"name":"Unidad de Neuroinflamaci\u00f3n, Departamento de Medicina Gen\u00f3mica y Toxicolog\u00eda Ambiental, Instituto de Investigaci\u00f3n Biom\u00e9dicas, Universidad Nacional Aut\u00f3noma de M\u00e9xico, Instituto Nacional de Neurolog\u00eda y Neurocirug\u00eda Manuel Velasco Su\u00e1rez (INNN-MVS), M\u00e9xico City 14269, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9932-0917","authenticated-orcid":false,"given":"Sergio","family":"Moreno Jim\u00e9nez","sequence":"additional","affiliation":[{"name":"Departamento de Neurocirug\u00eda, Instituto Nacional de Neurolog\u00eda y Neurocirug\u00eda Manuel Velasco Su\u00e1rez, M\u00e9xico City 14269, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8719-4589","authenticated-orcid":false,"given":"Roger","family":"Carrillo-Mezo","sequence":"additional","affiliation":[{"name":"Departamento de Neuroimagen, Instituto Nacional de Neurolog\u00eda y Neurocirug\u00eda Manuel Velasco Su\u00e1rez, M\u00e9xico City 14269, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8930-2202","authenticated-orcid":false,"given":"Agn\u00e8s","family":"Fleury","sequence":"additional","affiliation":[{"name":"Unidad de Neuroinflamaci\u00f3n, Departamento de Medicina Gen\u00f3mica y Toxicolog\u00eda Ambiental, Instituto de Investigaci\u00f3n Biom\u00e9dicas, Universidad Nacional Aut\u00f3noma de M\u00e9xico, Instituto Nacional de Neurolog\u00eda y Neurocirug\u00eda Manuel Velasco Su\u00e1rez (INNN-MVS), M\u00e9xico City 14269, Mexico"},{"name":"Cl\u00ednica de Neurocisticercosis, Instituto Nacional de Neurolog\u00eda y Neurocirug\u00eda Manuel Velasco Su\u00e1rez, M\u00e9xico City 14269, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2026,1,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1097\/QCO.0000000000000831","article-title":"Neurocysticercosis: An update on diagnosis, treatment, and prevention","volume":"35","author":"White","year":"2022","journal-title":"Curr. 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