{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T14:36:03Z","timestamp":1793889363217,"version":"4.8.0"},"reference-count":10,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T00:00:00Z","timestamp":1775174400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100011061","name":"Agence Fran\u00e7aise de D\u00e9veloppement","doi-asserted-by":"publisher","award":["CZ3246"],"award-info":[{"award-number":["CZ3246"]}],"id":[{"id":"10.13039\/501100011061","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011061","name":"Agence Fran\u00e7aise de D\u00e9veloppement","doi-asserted-by":"publisher","award":["CZZ3209"],"award-info":[{"award-number":["CZZ3209"]}],"id":[{"id":"10.13039\/501100011061","id-type":"DOI","asserted-by":"publisher"}]},{"award":["CZ3246"],"award-info":[{"award-number":["CZ3246"]}],"id":[{"id":"https:\/\/ror.org\/04tqhj682","id-type":"ROR","asserted-by":"publisher"}]},{"award":["CZZ3209"],"award-info":[{"award-number":["CZZ3209"]}],"id":[{"id":"https:\/\/ror.org\/04tqhj682","id-type":"ROR","asserted-by":"publisher"}]},{"name":"Global Centre for Health and Pandemic Prevention CAIDERA","award":["57592740"],"award-info":[{"award-number":["57592740"]}]},{"name":"German Academic Exchange Service"},{"id":[{"id":"https:\/\/ror.org\/039djdh30","id-type":"ROR","asserted-by":"publisher"}]},{"name":"German Federal Foreign Ministry"},{"id":[{"id":"https:\/\/ror.org\/01t8rk370","id-type":"ROR","asserted-by":"publisher"}]},{"name":"ANRS-MIE","award":["#ANRS0352b (ECTZ234766)"],"award-info":[{"award-number":["#ANRS0352b (ECTZ234766)"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathogens"],"abstract":"<jats:p>Hepatitis E virus (HEV) is a major cause of acute viral hepatitis worldwide, with zoonotic genotypes detected in humans and animals. In Africa, limited data exist on environmental HEV circulation. Here, we report the first detection of Rocahepevirus ratti (RHEV) in urban wastewater from Conakry, Guinea. From December 2024 to April 2025, Rocahepevirus ratti (RHEV) has been detected in 35 out of 180 urban untreated wastewater samples in Conakry, Guinea. The phylogenetic analysis of partial HEV ORF1 genome segments reveals clustering with African rodent RHEV strains, highlighting environmental contamination and potential zoonotic risk for human populations in proximity. This finding underscores the need for integrated One Health surveillance to monitor HEV transmission at the human\u2013animal\u2013environment interface in West Africa, particularly in Guinea.<\/jats:p>","DOI":"10.3390\/pathogens15040385","type":"journal-article","created":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T03:11:28Z","timestamp":1775445088000},"page":"385","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["First Detection of Rocahepevirus in Urban Wastewater from Guinea: A One Health Alert"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-4572-9482","authenticated-orcid":false,"given":"Bakary","family":"Doukour\u00e9","sequence":"first","affiliation":[{"name":"Institut Pasteur de Guin\u00e9e, Conakry BP 4416, Guinea"},{"name":"Institute for Tropical Medicine, University of T\u00fcbingen, 72074 T\u00fcbingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yann Le","family":"Pennec","sequence":"additional","affiliation":[{"name":"Institut Pasteur de Guin\u00e9e, Conakry BP 4416, Guinea"},{"name":"Immune Diseases, Microbiology and Innovative Therapies (IDMIT\/UMRS 1184), Universit\u00e9 Paris-Saclay, Inserm, CEA, 92265 Fontenay-aux-Roses, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ciss\u00e9","family":"Fatoumata","sequence":"additional","affiliation":[{"name":"Institut Pasteur de Guin\u00e9e, Conakry BP 4416, Guinea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramatoulaye","family":"Diallo","sequence":"additional","affiliation":[{"name":"Institut Pasteur de Guin\u00e9e, Conakry BP 4416, Guinea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Issiaga","family":"Tour\u00e9","sequence":"additional","affiliation":[{"name":"Institut Pasteur de Guin\u00e9e, Conakry BP 4416, Guinea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"No\u00ebl","family":"Tordo","sequence":"additional","affiliation":[{"name":"Institut Pasteur de Guin\u00e9e, Conakry BP 4416, Guinea"},{"name":"Virology Department, Institut Pasteur, 75015 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1825-1054","authenticated-orcid":false,"given":"Pierre","family":"Roques","sequence":"additional","affiliation":[{"name":"Institut Pasteur de Guin\u00e9e, Conakry BP 4416, Guinea"},{"name":"Immune Diseases, Microbiology and Innovative Therapies (IDMIT\/UMRS 1184), Universit\u00e9 Paris-Saclay, Inserm, CEA, 92265 Fontenay-aux-Roses, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,4,3]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1089\/vbz.2023.0104","article-title":"Seroprevalence and phylogenetic characterization of hepatitis E virus (Paslahepevirus balayani) in Guinean pig population","volume":"24","author":"Pennec","year":"2024","journal-title":"Vector Borne Zoonotic Dis."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/hepr.14062","article-title":"Recent advances in hepatitis E virus research and the Japanese clinical practice guidelines for hepatitis E virus infection","volume":"54","author":"Kanda","year":"2024","journal-title":"Hepatol. 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