{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T01:25:07Z","timestamp":1785547507720,"version":"3.56.0"},"reference-count":37,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2026,5,24]],"date-time":"2026-05-24T00:00:00Z","timestamp":1779580800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100017170","name":"Thailand Science Research and Innovation Fund","doi-asserted-by":"publisher","award":["FRB660041\/0227-WU02"],"award-info":[{"award-number":["FRB660041\/0227-WU02"]}],"id":[{"id":"10.13039\/501100017170","id-type":"DOI","asserted-by":"publisher"}]},{"award":["FRB660041\/0227-WU02"],"award-info":[{"award-number":["FRB660041\/0227-WU02"]}],"id":[{"id":"https:\/\/ror.org\/000025p04","id-type":"ROR","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathogens"],"abstract":"<jats:p>Strongyloides stercoralis (S. stercoralis) is an important soil-transmitted helminth that infests over 600 million people worldwide. However, data on its seroprevalence in remote regions, such as Thailand\u2019s island areas, remain limited. This study examined the seroprevalence and associated risk factors of anti-Strongyloides spp. IgG seropositivity among primary school children in Koh Yao, an island in southern Thailand. A total of 351 primary school children (156 males and 195 females) were included. The seroprevalence of anti-Strongyloides spp. IgG was determined using the Strongyloides-specific IgG antibodies ELISA, and risk factor data were collected through a questionnaire. Hematological parameters were also analyzed. Univariate and multivariate logistic regression analyses were used to assess associations between risk factors and anti-Strongyloides spp. IgG seropositivity. The seroprevalence of anti-Strongyloides spp. IgG was 3.7% (13\/351 participants). Analysis of the risk factors revealed that participants who drank filtered water exhibited lower odds of anti-Strongyloides spp. IgG seropositivity compared to those who drank tap or rainwater (AOR = 0.21, 95% CI 0.05\u20130.95, p = 0.043). However, due to the small number of seropositive cases, this association is hypothesis-generating and likely serves as a proxy for better household hygiene rather than a direct protective factor. This study is the first report on anti-Strongyloides spp. IgG seropositivity among primary school children in Koh Yao, southern Thailand, demonstrating a low seropositivity rate in this population. These findings provide location-specific information on modifiable risk behaviors, aiding in developing more effective control and prevention strategies for anti-Strongyloides spp. IgG seropositivity in Thailand\u2019s island area.<\/jats:p>","DOI":"10.3390\/pathogens15060566","type":"journal-article","created":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T02:32:28Z","timestamp":1779676348000},"page":"566","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Seroprevalence and Associated Factors of Anti-Strongyloides spp. IgG Among Primary School Children in Southern Thailand"],"prefix":"10.3390","volume":"15","author":[{"given":"Prasit","family":"Na-Ek","sequence":"first","affiliation":[{"name":"School of Medicine, Walailak University, Nakhon Si Thammarat 80160, Thailand"},{"name":"Center of Excellence in Tropical Pathobiology, Walailak University, Nakhon Si Thammarat 80160, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6894-8955","authenticated-orcid":false,"given":"Udomsak","family":"Narkkul","sequence":"additional","affiliation":[{"name":"School of Medicine, Walailak University, Nakhon Si Thammarat 80160, Thailand"},{"name":"Center of Excellence in Tropical Pathobiology, Walailak University, Nakhon Si Thammarat 80160, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2382-2333","authenticated-orcid":false,"given":"Nonthapan","family":"Phasuk","sequence":"additional","affiliation":[{"name":"School of Medicine, Walailak University, Nakhon Si Thammarat 80160, Thailand"},{"name":"Center of Excellence in Tropical Pathobiology, Walailak University, Nakhon Si Thammarat 80160, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1196-6735","authenticated-orcid":false,"given":"Stephen J.","family":"Scholand","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Arizona, Tucson, AZ 85724, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4826-9474","authenticated-orcid":false,"given":"Chuchard","family":"Punsawad","sequence":"additional","affiliation":[{"name":"School of Medicine, Walailak University, Nakhon Si Thammarat 80160, Thailand"},{"name":"Center of Excellence in Tropical Pathobiology, Walailak University, Nakhon Si Thammarat 80160, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,5,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/S0065-308X(08)60036-6","article-title":"Human strongyloidiasis","volume":"Volume 38","author":"Baker","year":"1996","journal-title":"Advances in Parasitology"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1017\/S0031182016000834","article-title":"Human infection with Strongyloides stercoralis and other related Strongyloides species","volume":"144","author":"Nutman","year":"2017","journal-title":"Parasitology"},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Punsawad, C., Phasuk, N., Bunratsami, S., Thongtup, K., Siripakonuaong, N., and Nongnaul, S. 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