{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T09:36:02Z","timestamp":1777455362410,"version":"3.51.4"},"reference-count":83,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2016,9,30]],"date-time":"2016-09-30T00:00:00Z","timestamp":1475193600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathogens"],"abstract":"<jats:p>Strongyloidiasis is an underestimated disease caused by the soil-transmitted parasite of the genus Strongyloides. It is prevalent in socioeconomically disadvantaged communities and it is estimated that global infection could be as high as 370 million people. This paper explores current methods of strongyloidiasis treatment, which rely on administration of anthelminthic drugs. However these drugs cannot prevent reinfection and drug resistance has already been observed in veterinary models. This highlights the need for a combined approach for controlling Strongyloides that includes both clinical treatment and environmental control methods. Currently, nematicides are widely used to control plant parasites. The review suggests that due to the species\u2019 similarity and similar modes of action, these nematicides could also be used to control animal and human parasitic nematodes in the environment.<\/jats:p>","DOI":"10.3390\/pathogens5040059","type":"journal-article","created":{"date-parts":[[2016,9,30]],"date-time":"2016-09-30T10:06:56Z","timestamp":1475230016000},"page":"59","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Advocating for both Environmental and Clinical Approaches to Control Human Strongyloidiasis"],"prefix":"10.3390","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9573-2818","authenticated-orcid":false,"given":"Meruyert","family":"Beknazarova","sequence":"first","affiliation":[{"name":"School of the Environment, Flinders University, GPO Box 2100, Adelaide 5001, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8940-3508","authenticated-orcid":false,"given":"Harriet","family":"Whiley","sequence":"additional","affiliation":[{"name":"School of the Environment, Flinders University, GPO Box 2100, Adelaide 5001, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5677-9576","authenticated-orcid":false,"given":"Kirstin","family":"Ross","sequence":"additional","affiliation":[{"name":"School of the Environment, Flinders University, GPO Box 2100, Adelaide 5001, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2016,9,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/S0065-308X(08)60036-6","article-title":"Human strongyloidiasis","volume":"38","author":"Grove","year":"1995","journal-title":"Adv. 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