{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T20:31:33Z","timestamp":1791232293739,"version":"4.1.0"},"reference-count":447,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2018,8,13]],"date-time":"2018-08-13T00:00:00Z","timestamp":1534118400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007201","name":"Utah Science Technology and Research","doi-asserted-by":"publisher","award":["A34637"],"award-info":[{"award-number":["A34637"]}],"id":[{"id":"10.13039\/100007201","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007201","name":"Utah Science Technology and Research","doi-asserted-by":"publisher","award":["A35813"],"award-info":[{"award-number":["A35813"]}],"id":[{"id":"10.13039\/100007201","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007199","name":"Utah Agricultural Experiment Station","doi-asserted-by":"publisher","award":["UTAO-1345"],"award-info":[{"award-number":["UTAO-1345"]}],"id":[{"id":"10.13039\/100007199","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathogens"],"abstract":"<jats:p>Japanese encephalitis virus (JEV), a mosquito-borne zoonotic flavivirus, is an enveloped positive-strand RNA virus that can cause a spectrum of clinical manifestations, ranging from mild febrile illness to severe neuroinvasive disease. Today, several killed and live vaccines are available in different parts of the globe for use in humans to prevent JEV-induced diseases, yet no antivirals are available to treat JEV-associated diseases. Despite the progress made in vaccine research and development, JEV is still a major public health problem in southern, eastern, and southeastern Asia, as well as northern Oceania, with the potential to become an emerging global pathogen. In viral replication, the entry of JEV into the cell is the first step in a cascade of complex interactions between the virus and target cells that is required for the initiation, dissemination, and maintenance of infection. Because this step determines cell\/tissue tropism and pathogenesis, it is a promising target for antiviral therapy. JEV entry is mediated by the viral glycoprotein E, which binds virions to the cell surface (attachment), delivers them to endosomes (endocytosis), and catalyzes the fusion between the viral and endosomal membranes (membrane fusion), followed by the release of the viral genome into the cytoplasm (uncoating). In this multistep process, a collection of host factors are involved. In this review, we summarize the current knowledge on the viral and cellular components involved in JEV entry into host cells, with an emphasis on the initial virus-host cell interactions on the cell surface.<\/jats:p>","DOI":"10.3390\/pathogens7030068","type":"journal-article","created":{"date-parts":[[2018,8,13]],"date-time":"2018-08-13T11:27:13Z","timestamp":1534159633000},"page":"68","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":69,"title":["Early Events in Japanese Encephalitis Virus Infection: Viral Entry"],"prefix":"10.3390","volume":"7","author":[{"given":"Sang-Im","family":"Yun","sequence":"first","affiliation":[{"name":"Department of Animal, Dairy, and Veterinary Sciences, College of Agriculture and Applied Sciences, Utah State University, Logan, UT 84322, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3974-3405","authenticated-orcid":false,"given":"Young-Min","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Animal, Dairy, and Veterinary Sciences, College of Agriculture and Applied Sciences, Utah State University, Logan, UT 84322, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2018,8,13]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1099\/jgv.0.000672","article-title":"ICTV virus taxonomy profile: Flaviviridae","volume":"98","author":"Simmonds","year":"2017","journal-title":"J. Gen. Virol."},{"key":"ref_2","unstructured":"King, A.M.Q., Adams, M.J., Carstens, E.B., and Lefkowitz, E.J. (2012). Virus Taxonomy: 9th Report of the International Committee on Taxonomy of Viruses, Elsevier Academic Press."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/S0065-3527(03)59008-X","article-title":"Origins, evolution, and vector\/host coadaptations within the genus Flavivirus","volume":"59","author":"Gould","year":"2003","journal-title":"Adv. Virus Res."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1038\/nrmicro1006","article-title":"Transmission cycles, host range, evolution and emergence of arboviral disease","volume":"2","author":"Weaver","year":"2004","journal-title":"Nat. Rev. Microbiol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"453","DOI":"10.20506\/rst.34.2.2371","article-title":"Tick-borne encephalitis","volume":"34","author":"Valarcher","year":"2015","journal-title":"Rev. Sci. Tech."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.vetmic.2009.08.025","article-title":"Zoonotic mosquito-borne flaviviruses: Worldwide presence of agents with proven pathogenicity and potential candidates of future emerging diseases","volume":"140","author":"Weissenbock","year":"2010","journal-title":"Vet. Microbiol."},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Kuno, G., Mackenzie, J.S., Junglen, S., Hubalek, Z., Plyusnin, A., and Gubler, D.J. (2017). Vertebrate reservoirs of arboviruses: Myth, synonym of amplifier, or reality?. Viruses, 9.","DOI":"10.3390\/v9070185"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1099\/0022-1317-81-3-781","article-title":"Phylogeny of the genus Flavivirus using complete coding sequences of arthropod-borne viruses and viruses with no known vector","volume":"81","author":"Billoir","year":"2000","journal-title":"J. Gen. Virol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"11773","DOI":"10.1128\/JVI.01543-15","article-title":"Ecuador Paraiso Escondido virus, a new flavivirus isolated from New World sand flies in Ecuador, is the first representative of a novel clade in the genus Flavivirus","volume":"89","author":"Alkan","year":"2015","journal-title":"J. Virol."},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Blitvich, B.J., and Firth, A.E. (2017). A review of flaviviruses that have no known arthropod vector. Viruses, 9.","DOI":"10.3390\/v9060154"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1927","DOI":"10.3390\/v7041927","article-title":"Insect-specific flaviviruses: A systematic review of their discovery, host range, mode of transmission, superinfection exclusion potential and genomic organization","volume":"7","author":"Blitvich","year":"2015","journal-title":"Viruses"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"4911","DOI":"10.3390\/v7092851","article-title":"Insect-specific virus discovery: Significance for the arbovirus community","volume":"7","author":"Bolling","year":"2015","journal-title":"Viruses"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1111\/j.1863-2378.2008.01208.x","article-title":"The zoonotic flaviviruses of southern, south-eastern and eastern Asia, and Australasia: The potential for emergent viruses","volume":"56","author":"Mackenzie","year":"2009","journal-title":"Zoonoses Public Health"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"S98","DOI":"10.1038\/nm1144","article-title":"Emerging flaviviruses: The spread and resurgence of Japanese encephalitis, West Nile and dengue viruses","volume":"10","author":"Mackenzie","year":"2004","journal-title":"Nat. Med."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1002\/rmv.712","article-title":"Neuroinvasive flavivirus infections","volume":"22","author":"Sips","year":"2012","journal-title":"Rev. Med. Virol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1007\/s13365-014-0285-z","article-title":"Flaviviruses, an expanding threat in public health: Focus on dengue, West Nile, and Japanese encephalitis virus","volume":"20","author":"Daep","year":"2014","journal-title":"J. Neurovirol."},{"key":"ref_17","first-page":"1","article-title":"The Japanese encephalitis serological group of flaviviruses: A brief introduction to the group","volume":"267","author":"Mackenzie","year":"2002","journal-title":"Curr. Top. Microbiol. Immunol."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1080\/1040841X.2016.1230974","article-title":"Waiting in the wings: The potential of mosquito transmitted flaviviruses to emerge","volume":"43","author":"Smith","year":"2017","journal-title":"Crit. Rev. Microbiol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.jneuroim.2017.03.001","article-title":"Zika virus: History, epidemiology, transmission, and clinical presentation","volume":"308","author":"Song","year":"2017","journal-title":"J. Neuroimmunol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0065-3527(08)00401-6","article-title":"The history and evolution of human dengue emergence","volume":"72","author":"Vasilakis","year":"2008","journal-title":"Adv. Virus Res."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.ijid.2016.04.025","article-title":"Yellow fever cases in Asia: Primed for an epidemic","volume":"48","author":"Wasserman","year":"2016","journal-title":"Int. J. Infect. Dis."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.vetmic.2009.08.024","article-title":"Zoonotic tick-borne flaviviruses","volume":"140","author":"Dobler","year":"2010","journal-title":"Vet. Microbiol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1056\/NEJMp058263","article-title":"Control of Japanese encephalitis\u2014Within our grasp?","volume":"355","author":"Solomon","year":"2006","journal-title":"N. Engl. J. Med."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.pneurobio.2010.01.008","article-title":"Overview: Japanese encephalitis","volume":"91","author":"Misra","year":"2010","journal-title":"Prog. Neurobiol."},{"key":"ref_25","first-page":"11","article-title":"Japanese encephalitis virus: Ecology and epidemiology","volume":"267","author":"Endy","year":"2002","journal-title":"Curr. Top. Microbiol. Immunol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3201\/eid1501.080311","article-title":"Past, present, and future of Japanese encephalitis","volume":"15","author":"Erlanger","year":"2009","journal-title":"Emerg. Infect. Dis."},{"key":"ref_27","unstructured":"Tabor, E. (2007). Emerging Viruses in Human Populations, Elsevier."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1146\/annurev.ento.54.110807.090510","article-title":"Ecology and geographical expansion of Japanese encephalitis virus","volume":"54","author":"Ritchie","year":"2009","journal-title":"Annu. Rev. Entomol."},{"key":"ref_29","first-page":"49","article-title":"Japanese encephalitis as an emerging virus: The emergence and spread of Japanese encephalitis virus in Australasia","volume":"267","author":"Mackenzie","year":"2002","journal-title":"Curr. Top. Microbiol. Immunol."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1136\/pmj.78.918.205","article-title":"Japanese viral encephalitis","volume":"78","author":"Tiroumourougane","year":"2002","journal-title":"Postgrad. Med. J."},{"key":"ref_31","unstructured":"World Health Organization (WHO) (2006). Japanese encephalitis vaccines. Wkly. Epidemiol. Rec., 81, 331\u2013340."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"263","DOI":"10.4161\/hv.26902","article-title":"Japanese encephalitis: The virus and vaccines","volume":"10","author":"Yun","year":"2014","journal-title":"Hum. Vaccin. Immunother."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"631","DOI":"10.4269\/ajtmh.2000.62.631","article-title":"Isolation of Japanese encephalitis virus from mosquitoes (Diptera: Culicidae) collected in the Western Province of Papua New Guinea, 1997\u20131998","volume":"62","author":"Johansen","year":"2000","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"282","DOI":"10.5694\/j.1326-5377.2004.tb06274.x","article-title":"Japanese encephalitis acquired near Port Moresby: Implications for residents and travellers to Papua New Guinea","volume":"181","author":"Hanson","year":"2004","journal-title":"Med. J. Aust."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"533","DOI":"10.5694\/j.1326-5377.1999.tb127878.x","article-title":"Japanese encephalitis in north Queensland, Australia, 1998","volume":"170","author":"Hanna","year":"1999","journal-title":"Med. J. Aust."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"256","DOI":"10.5694\/j.1326-5377.1996.tb124960.x","article-title":"An outbreak of Japanese encephalitis in the Torres Strait, Australia, 1995","volume":"165","author":"Hanna","year":"1996","journal-title":"Med. J. Aust."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"80","DOI":"10.4269\/ajtmh.1997.56.80","article-title":"Isolation of Japanese encephalitis virus from Culex annulirostris in Australia","volume":"56","author":"Ritchie","year":"1997","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"900","DOI":"10.3201\/eid0705.017524","article-title":"Wind-blown mosquitoes and introduction of Japanese encephalitis into Australia","volume":"7","author":"Ritchie","year":"2001","journal-title":"Emerg. Infect. Dis."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"21","DOI":"10.4269\/ajtmh.2006.75.21","article-title":"Short report: The first isolation of Japanese encephalitis virus from mosquitoes collected from mainland Australia","volume":"75","author":"Montgomery","year":"2006","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.3201\/eid1411.071368","article-title":"Domestic pigs and Japanese encephalitis virus infection, Australia","volume":"14","author":"Ritchie","year":"2008","journal-title":"Emerg. Infect. Dis."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1093\/infdis\/167.5.1053","article-title":"Outbreak of Japanese encephalitis on the island of Saipan, 1990","volume":"167","author":"Paul","year":"1993","journal-title":"J. Infect. Dis."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1111\/j.1348-0421.1994.tb01866.x","article-title":"Detection of West Nile and Japanese encephalitis viral genome sequences in cerebrospinal fluid from acute encephalitis cases in Karachi, Pakistan","volume":"38","author":"Igarashi","year":"1994","journal-title":"Microbiol. Immunol."},{"key":"ref_43","doi-asserted-by":"crossref","unstructured":"Li, M.H., Fu, S.H., Chen, W.X., Wang, H.Y., Guo, Y.H., Liu, Q.Y., Li, Y.X., Luo, H.M., Da, W., and Duo Ji, D.Z. (2011). Genotype V Japanese encephalitis virus is emerging. PLoS Negl. Trop. Dis., 5.","DOI":"10.1371\/journal.pntd.0001231"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"934","DOI":"10.3201\/eid1705.101417","article-title":"Japanese encephalitis, Tibet, China","volume":"17","author":"Li","year":"2011","journal-title":"Emerg. Infect. Dis."},{"key":"ref_45","doi-asserted-by":"crossref","unstructured":"Ravanini, P., Huhtamo, E., Ilaria, V., Crobu, M.G., Nicosia, A.M., Servino, L., Rivasi, F., Allegrini, S., Miglio, U., and Magri, A. (2012). Japanese encephalitis virus RNA detected in Culex pipiens mosquitoes in Italy. Euro Surveill, 17.","DOI":"10.2807\/ese.17.28.20221-en"},{"key":"ref_46","doi-asserted-by":"crossref","unstructured":"Platonov, A., Rossi, G., Karan, L., Mironov, K., Busani, L., and Rezza, G. (2012). Does the Japanese encephalitis virus (JEV) represent a threat for human health in Europe? Detection of JEV RNA sequences in birds collected in Italy. Euro Surveill, 17.","DOI":"10.2807\/ese.17.32.20241-en"},{"key":"ref_47","doi-asserted-by":"crossref","unstructured":"Zeller, H. (2012). Is Japanese encephalitis emerging in Europe?. Euro Surveill, 17.","DOI":"10.2807\/ese.17.32.20242-en"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1089\/vbz.2008.0052","article-title":"Potential for the emergence of Japanese encephalitis virus in California","volume":"9","author":"Nett","year":"2009","journal-title":"Vector Borne Zoonotic Dis."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"665","DOI":"10.4269\/ajtmh.1959.8.665","article-title":"Ecologic studies of Japanese encephalitis virus in Japan. III. Mosquito factors. Zootropism and vertical flight of Culex tritaeniorhynchus with observations on variations in collections from animal-baited traps in different habitats","volume":"8","author":"Scherer","year":"1959","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_50","doi-asserted-by":"crossref","unstructured":"Su, C.L., Yang, C.F., Teng, H.J., Lu, L.C., Lin, C., Tsai, K.H., Chen, Y.Y., Chen, L.Y., Chang, S.F., and Shu, P.Y. (2014). Molecular epidemiology of Japanese encephalitis virus in mosquitoes in Taiwan during 2005\u20132012. PLoS Negl. Trop. Dis., 8.","DOI":"10.1371\/journal.pntd.0003122"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1093\/jmedent\/34.6.651","article-title":"Japanese encephalitis in south Arcot district, Tamil Nadu, India: A three-year longitudinal study of vector abundance and infection frequency","volume":"34","author":"Gajanana","year":"1997","journal-title":"J. Med. Entomol."},{"key":"ref_52","doi-asserted-by":"crossref","unstructured":"Lindahl, J.F., Stahl, K., Chirico, J., Boqvist, S., Thu, H.T., and Magnusson, U. (2013). Circulation of Japanese encephalitis virus in pigs and mosquito vectors within Can Tho city, Vietnam. PLoS Negl. Trop. Dis., 7.","DOI":"10.1371\/journal.pntd.0002153"},{"key":"ref_53","doi-asserted-by":"crossref","unstructured":"Seo, H.J., Kim, H.C., Klein, T.A., Ramey, A.M., Lee, J.H., Kyung, S.G., Park, J.Y., Cho, Y.S., Cho, I.S., and Yeh, J.Y. (2013). Molecular detection and genotyping of Japanese encephalitis virus in mosquitoes during a 2010 outbreak in the Republic of Korea. PLoS ONE, 8.","DOI":"10.1371\/journal.pone.0055165"},{"key":"ref_54","doi-asserted-by":"crossref","unstructured":"Tao, Z., Liu, G., Wang, M., Wang, H., Lin, X., Song, L., Wang, S., Wang, H., Liu, X., and Cui, N. (2014). Molecular epidemiology of Japanese encephalitis virus in mosquitoes during an outbreak in China, 2013. Sci. Rep., 4.","DOI":"10.1038\/srep04908"},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1603\/ME11148","article-title":"Culex annulirostris (Diptera: Culicidae) host feeding patterns and Japanese encephalitis virus ecology in northern Australia","volume":"49","author":"Jansen","year":"2012","journal-title":"J. Med. Entomol."},{"key":"ref_56","first-page":"599","article-title":"Rates of infection with Japanese encephalitis virus of two culicine species of mosquito in Taiwan","volume":"44","author":"Okuno","year":"1971","journal-title":"Bull. World Health Organ."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"477","DOI":"10.4269\/ajtmh.1976.25.477","article-title":"Japanese encephalitis virus in Northern Taiwan, 1969\u20131973","volume":"25","author":"Detels","year":"1976","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1093\/jmedent\/29.3.436","article-title":"Japanese encephalitis virus in Bangkok: Factors influencing vector infections in three suburban communities","volume":"29","author":"Gingrich","year":"1992","journal-title":"J. Med. Entomol."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/0035-9203(93)90080-A","article-title":"Japanese encephalitis in Sri Lanka: Comparison of vector and virus ecology in different agro-climatic areas","volume":"87","author":"Peiris","year":"1993","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1093\/jmedent\/34.3.257","article-title":"Abundance, parity, and Japanese encephalitis virus infection of mosquitoes (Diptera: Culicidae) in Sepang District, Malaysia","volume":"34","author":"Vythilingam","year":"1997","journal-title":"J. Med. Entomol."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1093\/oxfordjournals.aje.a112008","article-title":"Study of Japanese encephalitis virus in Chiangmai Valley, Thailand. IV. Vector studies","volume":"100","author":"Gould","year":"1974","journal-title":"Am. J. Epidemiol."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1016\/0035-9203(86)90397-4","article-title":"Virus isolations from mosquitoes collected during the 1982 Japanese encephalitis epidemic in northern Thailand","volume":"80","author":"Leake","year":"1986","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"654","DOI":"10.4269\/ajtmh.1992.46.654","article-title":"Mosquito blood feeding patterns as a factor in the epidemiology of Japanese encephalitis in southern India","volume":"46","author":"Reuben","year":"1992","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_64","doi-asserted-by":"crossref","unstructured":"Kim, H., Cha, G.W., Jeong, Y.E., Lee, W.G., Chang, K.S., Roh, J.Y., Yang, S.C., Park, M.Y., Park, C., and Shin, E.H. (2015). Detection of Japanese encephalitis virus genotype V in Culex orientalis and Culex pipiens (Diptera: Culicidae) in Korea. PLoS ONE, 10.","DOI":"10.1371\/journal.pone.0116547"},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"3195","DOI":"10.1007\/s00436-014-3983-9","article-title":"Aedes japonicus japonicus (Diptera: Culicidae) from Germany have vector competence for Japanese encephalitis virus but are refractory to infection with West Nile virus","volume":"113","author":"Huber","year":"2014","journal-title":"Parasitol. Res."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/mve.12083","article-title":"Evaluation of a temperate climate mosquito, Ochlerotatus detritus (=Aedes detritus), as a potential vector of Japanese encephalitis virus","volume":"29","author":"Impoinvil","year":"2015","journal-title":"Med. Vet. Entomol."},{"key":"ref_67","doi-asserted-by":"crossref","unstructured":"De Wispelaere, M., Despres, P., and Choumet, V. (2017). European Aedes albopictus and Culex pipiens are competent vectors for Japanese encephalitis virus. PLoS Negl. Trop. Dis., 11.","DOI":"10.1371\/journal.pntd.0005294"},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1093\/jmedent\/34.6.745","article-title":"Susceptibility of three laboratory strains of Aedes albopictus (Diptera: Culicidae) to Japanese encephalitis virus from Taiwan","volume":"34","author":"Weng","year":"1997","journal-title":"J. Med. Entomol."},{"key":"ref_69","first-page":"611","article-title":"Vectors of Japanese encephalitis virus (JEV): Species complexes of the vectors","volume":"20","author":"Sucharit","year":"1989","journal-title":"Southeast Asian J. Trop. Med. Public Health"},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"732","DOI":"10.4269\/ajtmh.1989.41.732","article-title":"Japanese encephalitis virus infection in mosquitoes reared from field-collected immatures and in wild-caught males","volume":"41","author":"Dhanda","year":"1989","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"548","DOI":"10.4269\/ajtmh.1989.40.548","article-title":"Experimental vertical transmission of Japanese encephalitis virus by Culex tritaeniorhynchus and other mosquitoes","volume":"40","author":"Rosen","year":"1989","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"557","DOI":"10.4269\/ajtmh.1989.40.557","article-title":"A longitudinal study of the prevalence of Japanese encephalitis virus in adult and larval Culex tritaeniorhynchus mosquitoes in northern Taiwan","volume":"40","author":"Rosen","year":"1989","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1126\/science.203035","article-title":"Transovarial transmission of Japanese encephalitis virus by mosquitoes","volume":"199","author":"Rosen","year":"1978","journal-title":"Science"},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"49","DOI":"10.3201\/eid2401.171297","article-title":"Japanese encephalitis virus transmitted via blood transfusion, Hong Kong, China","volume":"24","author":"Cheng","year":"2018","journal-title":"Emerg. Infect. Dis."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"651","DOI":"10.4269\/ajtmh.1959.8.651","article-title":"Ecologic studies of Japanese encephalitis virus in Japan. II. Mosquito infection","volume":"8","author":"Buescher","year":"1959","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"719","DOI":"10.4269\/ajtmh.1959.8.719","article-title":"Ecologic studies of Japanese encephalitis virus in Japan. IX. Epidemiologic correlations and conclusions","volume":"8","author":"Buescher","year":"1959","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"698","DOI":"10.4269\/ajtmh.1959.8.698","article-title":"Ecologic studies of Japanese encephalitis virus in Japan. VI. Swine infection","volume":"8","author":"Scherer","year":"1959","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_78","first-page":"157","article-title":"Experimental studies on the susceptibility of domestic pigs to West Nile virus followed by Japanese encephalitis virus infection and vice versa","volume":"38","author":"Ilkal","year":"1994","journal-title":"Acta Virol."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"760","DOI":"10.4269\/ajtmh.2012.12-0141","article-title":"North American birds as potential amplifying hosts of Japanese encephalitis virus","volume":"87","author":"Nemeth","year":"2012","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"678","DOI":"10.4269\/ajtmh.1959.8.678","article-title":"Ecologic studies of Japanese encephalitis virus in Japan. IV. Avian infection","volume":"8","author":"Buescher","year":"1959","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1080\/00034983.1957.11685827","article-title":"Investigation of domestic pigs as a potential reservoir of Japanese B encephalitis virus on Singapore Island","volume":"51","author":"Hale","year":"1957","journal-title":"Ann. Trop. Med. Parasitol."},{"key":"ref_82","first-page":"17","article-title":"Japanese encephalitis in Malaya. II. Distribution of neutralizing antibodies in man and animals","volume":"59","author":"Pond","year":"1954","journal-title":"Am. J. Hyg."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"420","DOI":"10.4269\/ajtmh.1988.38.420","article-title":"Ecological studies of Japanese encephalitis virus in Hokkaido: Interepidemic outbreaks of swine abortion and evidence for the virus to overwinter locally","volume":"38","author":"Takashima","year":"1988","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_84","first-page":"363","article-title":"Experimental stillbirth in pregnant swine infected with Japanese encephalitis virus","volume":"24","author":"Shimizu","year":"1954","journal-title":"Jpn. J. Exp. Med."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"130","DOI":"10.7774\/cevr.2015.4.2.130","article-title":"The present and future of veterinary vaccines for Japanese encephalitis in Korea","volume":"4","author":"Nah","year":"2015","journal-title":"Clin. Exp. Vaccine Res."},{"key":"ref_86","first-page":"465","article-title":"The effect of vaccination with a live attenuated strain of Japanese encephalitis virus on stillbirths in swine in Taiwan","volume":"46","author":"Hsu","year":"1972","journal-title":"Bull. World Health Organ."},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"77","DOI":"10.4269\/ajtmh.1970.19.77","article-title":"Studies of arthropod-borne virus infections in Chiroptera. VI. Isolation of Japanese B encephalitis virus from naturally infected bats","volume":"19","author":"Sulkin","year":"1970","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"939","DOI":"10.3201\/eid1506.081525","article-title":"Japanese encephalitis viruses from bats in Yunnan, China","volume":"15","author":"Wang","year":"2009","journal-title":"Emerg. Infect. Dis."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"457","DOI":"10.4269\/ajtmh.2009.81.457","article-title":"Transmission of Japanese encephalitis virus from the black flying fox, Pteropus alecto, to Culex annulirostris mosquitoes, despite the absence of detectable viremia","volume":"81","author":"Smith","year":"2009","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"88","DOI":"10.4269\/ajtmh.1970.19.88","article-title":"Studies of arthropod-borne virus infections in Chiroptera. VII. Serologic evidence of natural Japanese B encephalitis virus infection in bats","volume":"19","author":"Miura","year":"1970","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"418","DOI":"10.4269\/ajtmh.1966.15.418","article-title":"Studies of arthropod-borne virus infections in Chiroptera. IV. The immune response of the big brown bat (Eptesicus f. fuscus) maintained at various environmental temperatures to experimental Japanese B encephalitis virus infection","volume":"15","author":"Sulkin","year":"1966","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_92","first-page":"101","article-title":"Japanese B encephalitis in bats during simulated hibernation","volume":"67","year":"1958","journal-title":"Am. J. Hyg."},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1136\/vr.157.6.168","article-title":"Japanese encephalitis in a racing thoroughbred gelding in Hong Kong","volume":"157","author":"Lam","year":"2005","journal-title":"Vet. Rec."},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1111\/j.2042-3306.1972.tb03900.x","article-title":"Japanese encephalitis in horses in Japan","volume":"4","author":"Nakamura","year":"1972","journal-title":"Equine Vet. J."},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1292\/jvms.61.877","article-title":"Seroepizootiological survey of Japanese encephalitis virus and Getah virus in regional horse race tracks from 1991 to 1997 in Japan","volume":"61","author":"Sugiura","year":"1999","journal-title":"J. Vet. Med. Sci."},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1292\/jvms.68.293","article-title":"Isolation and genetic analysis of Japanese encephalitis virus from a diseased horse in Japan","volume":"68","author":"Yamanaka","year":"2006","journal-title":"J. Vet. Med. Sci."},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"742","DOI":"10.4269\/ajtmh.1964.13.742","article-title":"Experimental infection of horses with Japanese encephalitis virus by mosquito bite","volume":"13","author":"Gould","year":"1964","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1016\/j.vaccine.2005.07.083","article-title":"Analysis of yearly changes in levels of antibodies to Japanese encephalitis virus nonstructural 1 protein in racehorses in central Japan shows high levels of natural virus activity still exist","volume":"24","author":"Konishi","year":"2006","journal-title":"Vaccine"},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"111","DOI":"10.4142\/jvs.2012.13.2.111","article-title":"Isolation and genetic characterization of Japanese encephalitis virus from equines in India","volume":"13","author":"Gulati","year":"2012","journal-title":"J. Vet. Sci."},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1111\/j.1751-0813.1968.tb04908.x","article-title":"Japanese B encephalitis in a horse","volume":"44","author":"Kheng","year":"1968","journal-title":"Aust. Vet. J."},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"381","DOI":"10.4142\/jvs.2008.9.4.381","article-title":"Serosurveillance for Japanese encephalitis, Akabane, and Aino viruses for Thoroughbred horses in Korea","volume":"9","author":"Yang","year":"2008","journal-title":"J. Vet. Sci."},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"3448","DOI":"10.1128\/JCM.00737-13","article-title":"Nonsuppurative encephalomyelitis in a calf in Japan and isolation of Japanese encephalitis virus genotype 1 from the affected calf","volume":"51","author":"Katayama","year":"2013","journal-title":"J. Clin. Microbiol."},{"key":"ref_103","doi-asserted-by":"crossref","unstructured":"Kako, N., Suzuki, S., Sugie, N., Kato, T., Yanase, T., Yamakawa, M., and Shirafuji, H. (2014). Japanese encephalitis in a 114-month-old cow: Pathological investigation of the affected cow and genetic characterization of Japanese encephalitis virus isolate. BMC Vet. Res., 10.","DOI":"10.1186\/1746-6148-10-63"},{"key":"ref_104","first-page":"111","article-title":"Studies on Japanese encephalitis of cattle\u20141. Bovine encephalitis caused by natural infection with Japanese encephalitis virus","volume":"23","author":"Shimizu","year":"1951","journal-title":"Natl. Inst. Anim. Health Q."},{"key":"ref_105","first-page":"119","article-title":"Studies on Japanese encephalitis of cattle\u20142. Experimental infection of calves with virus of Japanese encephalitis","volume":"23","author":"Shimizu","year":"1951","journal-title":"Natl. Inst. Anim. Health Q."},{"key":"ref_106","doi-asserted-by":"crossref","first-page":"45","DOI":"10.4142\/jvs.2007.8.1.45","article-title":"Sero-survey on Aino, Akabane, Chuzan, bovine ephemeral fever and Japanese encephalitis virus of cattle and swine in Korea","volume":"8","author":"Lim","year":"2007","journal-title":"J. Vet. Sci."},{"key":"ref_107","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1016\/0035-9203(88)90536-6","article-title":"Absence of viraemia in cattle after experimental infection with Japanese encephalitis virus","volume":"82","author":"Ilkal","year":"1988","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"key":"ref_108","first-page":"242","article-title":"Sero-positivity of domestic animals against Japanese encephalitis in Bareilly area, U.P","volume":"27","author":"Mall","year":"1995","journal-title":"J. Commun. Dis."},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.cimid.2016.08.002","article-title":"Serological evidence of widespread West Nile virus and Japanese encephalitis virus infection in native domestic ducks (Anas platyrhynchos var domesticus) in Kuttanad region, Kerala, India","volume":"48","author":"Kalaiyarasu","year":"2016","journal-title":"Comp. Immunol. Microbiol. Infect. Dis."},{"key":"ref_110","first-page":"881","article-title":"Experimental viraemia and transmission of Japanese encephalitis virus by mosquitoes in domestic ducks","volume":"66","author":"Dhanda","year":"1977","journal-title":"Indian J. Med. Res."},{"key":"ref_111","doi-asserted-by":"crossref","first-page":"309","DOI":"10.7883\/yoken.JJID.2007.309","article-title":"Survey of the antibody against Japanese encephalitis virus in Ryukyu wild boars (Sus scrofa riukiuanus) in Okinawa, Japan","volume":"60","author":"Nidaira","year":"2007","journal-title":"Jpn. J. Infect. Dis."},{"key":"ref_112","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1292\/jvms.71.1035","article-title":"Detection of antibodies against Japanese encephalitis virus in raccoons, raccoon dogs and wild boars in Japan","volume":"71","author":"Ohno","year":"2009","journal-title":"J. Vet. Med. Sci."},{"key":"ref_113","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1017\/S0950268806007710","article-title":"Detection of antibodies to Japanese encephalitis virus in the wild boars in Hiroshima prefecture, Japan","volume":"135","author":"Hamano","year":"2007","journal-title":"Epidemiol. Infect."},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"197","DOI":"10.4142\/jvs.2007.8.2.197","article-title":"The seroprevalence of Japanese encephalitis virus in goats raised in Korea","volume":"8","author":"Yang","year":"2007","journal-title":"J. Vet. Sci."},{"key":"ref_115","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.vetmic.2017.01.014","article-title":"Japanese encephalitis virus infection, diagnosis and control in domestic animals","volume":"201","author":"Mansfield","year":"2017","journal-title":"Vet. Microbiol."},{"key":"ref_116","doi-asserted-by":"crossref","first-page":"242","DOI":"10.4269\/ajtmh.13-0161","article-title":"Age-related susceptibility to Japanese encephalitis virus in domestic ducklings and chicks","volume":"90","author":"Cleton","year":"2014","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_117","doi-asserted-by":"crossref","unstructured":"Ricklin, M.E., Garcia-Nicolas, O., Brechbuhl, D., Python, S., Zumkehr, B., Posthaus, H., Oevermann, A., and Summerfield, A. (2016). Japanese encephalitis virus tropism in experimentally infected pigs. Vet. Res., 47.","DOI":"10.1186\/s13567-016-0319-z"},{"key":"ref_118","doi-asserted-by":"crossref","unstructured":"Ricklin, M.E., Garcia-Nicolas, O., Brechbuhl, D., Python, S., Zumkehr, B., Nougairede, A., Charrel, R.N., Posthaus, H., Oevermann, A., and Summerfield, A. (2016). Vector-free transmission and persistence of Japanese encephalitis virus in pigs. Nat. Commun., 7.","DOI":"10.1038\/ncomms10832"},{"key":"ref_119","doi-asserted-by":"crossref","unstructured":"Miller, R.H., Masuoka, P., Klein, T.A., Kim, H.C., Somer, T., and Grieco, J. (2012). Ecological niche modeling to estimate the distribution of Japanese encephalitis virus in Asia. PLoS Negl. Trop. Dis., 6.","DOI":"10.1371\/journal.pntd.0001678"},{"key":"ref_120","doi-asserted-by":"crossref","unstructured":"Le Flohic, G., Porphyre, V., Barbazan, P., and Gonzalez, J.P. (2013). Review of climate, landscape, and viral genetics as drivers of the Japanese encephalitis virus ecology. PLoS Negl. Trop. Dis., 7.","DOI":"10.1371\/journal.pntd.0002208"},{"key":"ref_121","doi-asserted-by":"crossref","unstructured":"Lord, J.S., Gurley, E.S., and Pulliam, J.R. (2015). Rethinking Japanese encephalitis virus transmission: A framework for implicating host and vector species. PLoS Negl. Trop. Dis., 9.","DOI":"10.1371\/journal.pntd.0004074"},{"key":"ref_122","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1099\/vir.0.062208-0","article-title":"Flavivirus RNA methylation","volume":"95","author":"Dong","year":"2014","journal-title":"J. Gen. Virol."},{"key":"ref_123","doi-asserted-by":"crossref","first-page":"4640","DOI":"10.3390\/v7082837","article-title":"Flaviviral replication complex: Coordination between RNA synthesis and 5\u2032-RNA capping","volume":"7","author":"Klema","year":"2015","journal-title":"Viruses"},{"key":"ref_124","doi-asserted-by":"crossref","first-page":"8362","DOI":"10.1128\/JVI.00814-06","article-title":"West Nile virus 5\u2032-cap structure is formed by sequential guanine N-7 and ribose 2\u2032-O methylations by nonstructural protein 5","volume":"80","author":"Ray","year":"2006","journal-title":"J. Virol."},{"key":"ref_125","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1038\/nature09489","article-title":"2\u2032-O methylation of the viral mRNA cap evades host restriction by IFIT family members","volume":"468","author":"Daffis","year":"2010","journal-title":"Nature"},{"key":"ref_126","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1038\/ni.1979","article-title":"Ribose 2\u2032-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5","volume":"12","author":"Zust","year":"2011","journal-title":"Nat. Immunol."},{"key":"ref_127","doi-asserted-by":"crossref","first-page":"7909","DOI":"10.1128\/JVI.02541-08","article-title":"3\u2032 cis-acting elements that contribute to the competence and efficiency of Japanese encephalitis virus genome replication: Functional importance of sequence duplications, deletions, and substitutions","volume":"83","author":"Yun","year":"2009","journal-title":"J. Virol."},{"key":"ref_128","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.1261\/rna.993608","article-title":"A complex RNA motif defined by three discontinuous 5-nucleotide-long strands is essential for flavivirus RNA replication","volume":"14","author":"Song","year":"2008","journal-title":"RNA"},{"key":"ref_129","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.virusres.2015.02.006","article-title":"Functions of the 3\u2032 and 5\u2032 genome RNA regions of members of the genus Flavivirus","volume":"206","author":"Brinton","year":"2015","journal-title":"Virus Res."},{"key":"ref_130","doi-asserted-by":"crossref","unstructured":"Ng, W.C., Soto-Acosta, R., Bradrick, S.S., Garcia-Blanco, M.A., and Ooi, E.E. (2017). The 5\u2032 and 3\u2032 untranslated regions of the flaviviral genome. Viruses, 9.","DOI":"10.3390\/v9060137"},{"key":"ref_131","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.tim.2016.01.002","article-title":"RNA structure duplications and flavivirus host adaptation","volume":"24","author":"Villordo","year":"2016","journal-title":"Trends Microbiol."},{"key":"ref_132","doi-asserted-by":"crossref","first-page":"5133","DOI":"10.1128\/JVI.78.10.5133-5138.2004","article-title":"Accumulation of a 3\u2032-terminal genome fragment in Japanese encephalitis virus-infected mammalian and mosquito cells","volume":"78","author":"Lin","year":"2004","journal-title":"J. Virol."},{"key":"ref_133","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/j.chom.2008.10.007","article-title":"A highly structured, nuclease-resistant, noncoding RNA produced by flaviviruses is required for pathogenicity","volume":"4","author":"Pijlman","year":"2008","journal-title":"Cell Host Microbe"},{"key":"ref_134","doi-asserted-by":"crossref","first-page":"11395","DOI":"10.1128\/JVI.01047-10","article-title":"An RNA pseudoknot is required for production of yellow fever virus subgenomic RNA by the host nuclease XRN1","volume":"84","author":"Silva","year":"2010","journal-title":"J. Virol."},{"key":"ref_135","doi-asserted-by":"crossref","first-page":"11407","DOI":"10.1128\/JVI.01159-10","article-title":"RNA structures required for production of subgenomic flavivirus RNA","volume":"84","author":"Funk","year":"2010","journal-title":"J. Virol."},{"key":"ref_136","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1126\/science.aah3963","article-title":"Zika virus produces noncoding RNAs using a multi-pseudoknot structure that confounds a cellular exonuclease","volume":"354","author":"Akiyama","year":"2016","journal-title":"Science"},{"key":"ref_137","doi-asserted-by":"crossref","first-page":"2029","DOI":"10.1261\/rna.034330.112","article-title":"A noncoding RNA produced by arthropod-borne flaviviruses inhibits the cellular exoribonuclease XRN1 and alters host mRNA stability","volume":"18","author":"Moon","year":"2012","journal-title":"RNA"},{"key":"ref_138","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.coviro.2014.04.002","article-title":"Flavivirus RNAi suppression: Decoding non-coding RNA","volume":"7","author":"Pijlman","year":"2014","journal-title":"Curr. Opin. Virol."},{"key":"ref_139","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.virusres.2015.01.026","article-title":"Functional non-coding RNAs derived from the flavivirus 3\u2032 untranslated region","volume":"206","author":"Clarke","year":"2015","journal-title":"Virus Res."},{"key":"ref_140","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.virusres.2015.09.009","article-title":"Standing your ground to exoribonucleases: Function of flavivirus long non-coding RNAs","volume":"212","author":"Charley","year":"2016","journal-title":"Virus Res."},{"key":"ref_141","doi-asserted-by":"crossref","unstructured":"Kim, J.K., Kim, J.M., Song, B.H., Yun, S.I., Yun, G.N., Byun, S.J., and Lee, Y.M. (2015). Profiling of viral proteins expressed from the genomic RNA of Japanese encephalitis virus using a panel of 15 region-specific polyclonal rabbit antisera: Implications for viral gene expression. PLoS ONE, 10.","DOI":"10.1371\/journal.pone.0124318"},{"key":"ref_142","unstructured":"Knipe, D.M., Howley, P.M., Cohen, J.I., Griffin, D.E., Lamb, R.A., Martin, M.A., Racaniello, V.R., and Roizman, B. (2013). Fields Virology, Wolters Kluwer Health."},{"key":"ref_143","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/0042-6822(87)90208-X","article-title":"Expression of Japanese encephalitis virus antigens in Escherichia coli","volume":"158","author":"Mason","year":"1987","journal-title":"Virology"},{"key":"ref_144","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/0042-6822(90)90470-C","article-title":"Production of yellow fever virus proteins in infected cells: Identification of discrete polyprotein species and analysis of cleavage kinetics using region-specific polyclonal antisera","volume":"177","author":"Chambers","year":"1990","journal-title":"Virology"},{"key":"ref_145","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/0042-6822(85)90156-4","article-title":"Sequence analysis of the viral core protein and the membrane-associated proteins V1 and NV2 of the flavivirus West Nile virus and of the genome sequence for these proteins","volume":"145","author":"Castle","year":"1985","journal-title":"Virology"},{"key":"ref_146","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/0042-6822(85)90129-1","article-title":"Sequence analysis of the membrane protein V3 of the flavivirus West Nile virus and of its gene","volume":"147","author":"Wengler","year":"1985","journal-title":"Virology"},{"key":"ref_147","doi-asserted-by":"crossref","first-page":"6218","DOI":"10.1073\/pnas.90.13.6218","article-title":"Flavivirus premembrane protein cleavage and spike heterodimer secretion require the function of the viral proteinase NS3","volume":"90","author":"Lobigs","year":"1993","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_148","doi-asserted-by":"crossref","first-page":"2141","DOI":"10.1128\/JVI.72.3.2141-2149.1998","article-title":"Signal peptidase cleavage at the flavivirus C-prM junction: Dependence on the viral NS2B-3 protease for efficient processing requires determinants in C, the signal peptide, and prM","volume":"72","author":"Stocks","year":"1998","journal-title":"J. Virol."},{"key":"ref_149","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.antiviral.2015.03.014","article-title":"The flavivirus NS2B-NS3 protease-helicase as a target for antiviral drug development","volume":"118","author":"Luo","year":"2015","journal-title":"Antivir. Res."},{"key":"ref_150","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/0042-6822(86)90082-6","article-title":"Primary structure of the West Nile flavivirus genome region coding for all nonstructural proteins","volume":"149","author":"Castle","year":"1986","journal-title":"Virology"},{"key":"ref_151","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1099\/0022-1317-69-1-23","article-title":"Gene mapping and positive identification of the non-structural proteins NS2A, NS2B, NS3, NS4B and NS5 of the flavivirus Kunjin and their cleavage sites","volume":"69","author":"Speight","year":"1988","journal-title":"J. Gen. Virol."},{"key":"ref_152","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/0042-6822(91)90540-R","article-title":"Processing of nonstructural proteins NS4A and NS4B of dengue 2 virus In vitro and in vivo","volume":"185","author":"Preugschat","year":"1991","journal-title":"Virology"},{"key":"ref_153","doi-asserted-by":"crossref","first-page":"2327","DOI":"10.1128\/jvi.67.4.2327-2335.1993","article-title":"Cleavage at a novel site in the NS4A region by the yellow fever virus NS2B-3 proteinase is a prerequisite for processing at the downstream 4A\/4B signalase site","volume":"67","author":"Lin","year":"1993","journal-title":"J. Virol."},{"key":"ref_154","doi-asserted-by":"crossref","first-page":"3794","DOI":"10.1128\/jvi.68.6.3794-3802.1994","article-title":"NS2B-3 proteinase-mediated processing in the yellow fever virus structural region: In vitro and in vivo studies","volume":"68","author":"Amberg","year":"1994","journal-title":"J. Virol."},{"key":"ref_155","doi-asserted-by":"crossref","first-page":"5765","DOI":"10.1128\/jvi.68.9.5765-5771.1994","article-title":"Processing of the intracellular form of the West Nile virus capsid protein by the viral NS2B-NS3 protease: An In vitro study","volume":"68","author":"Yamshchikov","year":"1994","journal-title":"J. Virol."},{"key":"ref_156","doi-asserted-by":"crossref","first-page":"8475","DOI":"10.1128\/jvi.71.11.8475-8481.1997","article-title":"Proteolytic activation of tick-borne encephalitis virus by furin","volume":"71","author":"Stadler","year":"1997","journal-title":"J. Virol."},{"key":"ref_157","doi-asserted-by":"crossref","first-page":"1852","DOI":"10.1128\/jvi.63.5.1852-1860.1989","article-title":"Proper processing of dengue virus nonstructural glycoprotein NS1 requires the N-terminal hydrophobic signal sequence and the downstream nonstructural protein NS2A","volume":"63","author":"Falgout","year":"1989","journal-title":"J. Virol."},{"key":"ref_158","doi-asserted-by":"crossref","first-page":"7232","DOI":"10.1128\/jvi.69.11.7232-7243.1995","article-title":"Evidence that flavivirus NS1-NS2A cleavage is mediated by a membrane-bound host protease in the endoplasmic reticulum","volume":"69","author":"Falgout","year":"1995","journal-title":"J. Virol."},{"key":"ref_159","doi-asserted-by":"crossref","first-page":"4573","DOI":"10.1128\/jvi.64.9.4573-4577.1990","article-title":"Cleavage of dengue virus NS1-NS2A requires an octapeptide sequence at the C terminus of NS1","volume":"64","author":"Hori","year":"1990","journal-title":"J. Virol."},{"key":"ref_160","doi-asserted-by":"crossref","unstructured":"Firth, A.E., and Atkins, J.F. (2009). A conserved predicted pseudoknot in the NS2A-encoding sequence of West Nile and Japanese encephalitis flaviviruses suggests NS1\u2032 may derive from ribosomal frameshifting. Virol. J., 6.","DOI":"10.1186\/1743-422X-6-14"},{"key":"ref_161","doi-asserted-by":"crossref","first-page":"1641","DOI":"10.1128\/JVI.01979-09","article-title":"NS1\u2032 of flaviviruses in the Japanese encephalitis virus serogroup is a product of ribosomal frameshifting and plays a role in viral neuroinvasiveness","volume":"84","author":"Melian","year":"2010","journal-title":"J. Virol."},{"key":"ref_162","doi-asserted-by":"crossref","first-page":"1959","DOI":"10.1099\/vir.0.043844-0","article-title":"A single nucleotide mutation in NS2A of Japanese encephalitis-live vaccine virus (SA14-14-2) ablates NS1\u2032 formation and contributes to attenuation","volume":"93","author":"Ye","year":"2012","journal-title":"J. Gen. Virol."},{"key":"ref_163","doi-asserted-by":"crossref","first-page":"2575","DOI":"10.1099\/jgv.0.000574","article-title":"Comparison of the live-attenuated Japanese encephalitis vaccine SA14-14-2 strain with its pre-attenuated virulent parent SA14 strain: Similarities and differences In vitro and in vivo","volume":"97","author":"Yun","year":"2016","journal-title":"J. Gen. Virol."},{"key":"ref_164","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0168-1702(03)00181-3","article-title":"Molecular characterization of the full-length genome of the Japanese encephalitis viral strain K87P39","volume":"96","author":"Yun","year":"2003","journal-title":"Virus Res."},{"key":"ref_165","doi-asserted-by":"crossref","first-page":"6450","DOI":"10.1128\/JVI.77.11.6450-6465.2003","article-title":"Development and application of a reverse genetics system for Japanese encephalitis virus","volume":"77","author":"Yun","year":"2003","journal-title":"J. Virol."},{"key":"ref_166","doi-asserted-by":"crossref","first-page":"4609","DOI":"10.1128\/JVI.02424-12","article-title":"Membrane topology and function of dengue virus NS2A protein","volume":"87","author":"Xie","year":"2013","journal-title":"J. Virol."},{"key":"ref_167","doi-asserted-by":"crossref","first-page":"2244","DOI":"10.1016\/j.bbamem.2015.06.010","article-title":"Membrane topology of NS2B of dengue virus revealed by NMR spectroscopy","volume":"1848","author":"Li","year":"2015","journal-title":"Biochim. Biophys. Acta"},{"key":"ref_168","doi-asserted-by":"crossref","first-page":"3455","DOI":"10.1128\/JVI.03453-14","article-title":"Characterization of dengue virus NS4A and NS4B protein interaction","volume":"89","author":"Zou","year":"2015","journal-title":"J. Virol."},{"key":"ref_169","doi-asserted-by":"crossref","first-page":"8854","DOI":"10.1074\/jbc.M512697200","article-title":"Subcellular localization and membrane topology of the dengue virus type 2 non-structural protein 4B","volume":"281","author":"Miller","year":"2006","journal-title":"J. Biol. Chem."},{"key":"ref_170","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.virusres.2016.10.005","article-title":"The flavivirus capsid protein: Structure, function and perspectives towards drug design","volume":"227","author":"Oliveira","year":"2017","journal-title":"Virus Res."},{"key":"ref_171","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1016\/j.str.2004.04.024","article-title":"West Nile virus core protein; tetramer structure and ribbon formation","volume":"12","author":"Dokland","year":"2004","journal-title":"Structure"},{"key":"ref_172","doi-asserted-by":"crossref","first-page":"3414","DOI":"10.1073\/pnas.0305892101","article-title":"Solution structure of dengue virus capsid protein reveals another fold","volume":"101","author":"Ma","year":"2004","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_173","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1016\/j.jmb.2018.02.006","article-title":"Crystal structure of the capsid protein from Zika virus","volume":"430","author":"Shang","year":"2018","journal-title":"J. Mol. Biol."},{"key":"ref_174","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1016\/S0092-8674(02)00660-8","article-title":"Structure of dengue virus: Implications for flavivirus organization, maturation, and fusion","volume":"108","author":"Kuhn","year":"2002","journal-title":"Cell"},{"key":"ref_175","doi-asserted-by":"crossref","unstructured":"Mukhopadhyay, S., Kim, B.S., Chipman, P.R., Rossmann, M.G., and Kuhn, R.J. (2003). Structure of West Nile virus. Science, 302.","DOI":"10.1126\/science.1089316"},{"key":"ref_176","doi-asserted-by":"crossref","unstructured":"Wang, X., Li, S.H., Zhu, L., Nian, Q.G., Yuan, S., Gao, Q., Hu, Z., Ye, Q., Li, X.F., and Xie, D.Y. (2017). Near-atomic structure of Japanese encephalitis virus reveals critical determinants of virulence and stability. Nat. Commun., 8.","DOI":"10.1038\/s41467-017-00024-6"},{"key":"ref_177","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1038\/nature17994","article-title":"Structure of the thermally stable Zika virus","volume":"533","author":"Kostyuchenko","year":"2016","journal-title":"Nature"},{"key":"ref_178","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1126\/science.aaf5316","article-title":"The 3.8 A resolution cryo-EM structure of Zika virus","volume":"352","author":"Sirohi","year":"2016","journal-title":"Science"},{"key":"ref_179","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1038\/nsmb.2463","article-title":"Cryo-EM structure of the mature dengue virus at 3.5-A resolution","volume":"20","author":"Zhang","year":"2013","journal-title":"Nat. Struct. Mol. Biol."},{"key":"ref_180","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1038\/nm0897-866","article-title":"Dengue virus infectivity depends on envelope protein binding to target cell heparan sulfate","volume":"3","author":"Chen","year":"1997","journal-title":"Nat. Med."},{"key":"ref_181","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1128\/JVI.80.3.1290-1301.2006","article-title":"West Nile virus discriminates between DC-SIGN and DC-SIGNR for cellular attachment and infection","volume":"80","author":"Davis","year":"2006","journal-title":"J. Virol."},{"key":"ref_182","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1038\/sj.embor.embor866","article-title":"Dendritic-cell-specific ICAM3-grabbing non-integrin is essential for the productive infection of human dendritic cells by mosquito-cell-derived dengue viruses","volume":"4","author":"Altmeyer","year":"2003","journal-title":"EMBO Rep."},{"key":"ref_183","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/j.cell.2005.11.042","article-title":"Cryo-EM reconstruction of dengue virus in complex with the carbohydrate recognition domain of DC-SIGN","volume":"124","author":"Pokidysheva","year":"2006","journal-title":"Cell"},{"key":"ref_184","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1084\/jem.20021840","article-title":"DC-SIGN (CD209) mediates dengue virus infection of human dendritic cells","volume":"197","author":"Tassaneetrithep","year":"2003","journal-title":"J. Exp. Med."},{"key":"ref_185","doi-asserted-by":"crossref","first-page":"8880","DOI":"10.1128\/JVI.00354-15","article-title":"Biology of Zika virus infection in human skin cells","volume":"89","author":"Hamel","year":"2015","journal-title":"J. Virol."},{"key":"ref_186","doi-asserted-by":"crossref","first-page":"69","DOI":"10.3390\/v6010069","article-title":"Flavivirus entry receptors: An update","volume":"6","author":"Meertens","year":"2013","journal-title":"Viruses"},{"key":"ref_187","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.coviro.2012.12.001","article-title":"Flaviviruses: Braking the entering","volume":"3","author":"Pierson","year":"2013","journal-title":"Curr. Opin. Virol."},{"key":"ref_188","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1002\/rmv.1868","article-title":"Japanese encephalitis virus invasion of cell: Allies and alleys","volume":"26","author":"Nain","year":"2016","journal-title":"Rev. Med. Virol."},{"key":"ref_189","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1099\/vir.0.83357-0","article-title":"Functional entry of dengue virus into Aedes albopictus mosquito cells is dependent on clathrin-mediated endocytosis","volume":"89","author":"Acosta","year":"2008","journal-title":"J. Gen. Virol."},{"key":"ref_190","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.virol.2006.01.022","article-title":"Analysis of the endocytic pathway mediating the infectious entry of mosquito-borne flavivirus West Nile into Aedes albopictus mosquito (C6\/36) cells","volume":"349","author":"Chu","year":"2006","journal-title":"Virology"},{"key":"ref_191","doi-asserted-by":"crossref","first-page":"10543","DOI":"10.1128\/JVI.78.19.10543-10555.2004","article-title":"Infectious entry of West Nile virus occurs through a clathrin-mediated endocytic pathway","volume":"78","author":"Chu","year":"2004","journal-title":"J. Virol."},{"key":"ref_192","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.virol.2008.05.012","article-title":"Endocytic pathway followed by dengue virus to infect the mosquito cell line C6\/36 HT","volume":"378","author":"Mosso","year":"2008","journal-title":"Virology"},{"key":"ref_193","doi-asserted-by":"crossref","unstructured":"Van der Schaar, H.M., Rust, M.J., Chen, C., van der Ende-Metselaar, H., Wilschut, J., Zhuang, X., and Smit, J.M. (2008). Dissecting the cell entry pathway of dengue virus by single-particle tracking in living cells. PLoS Pathog., 4.","DOI":"10.1371\/journal.ppat.1000244"},{"key":"ref_194","doi-asserted-by":"crossref","first-page":"e01113","DOI":"10.1128\/JVI.01113-17","article-title":"Rab5 and Rab11 are required for clathrin-dependent endocytosis of Japanese encephalitis virus in BHK-21 cells","volume":"91","author":"Liu","year":"2017","journal-title":"J. Virol."},{"key":"ref_195","doi-asserted-by":"crossref","unstructured":"Yang, S., He, M., Liu, X., Li, X., Fan, B., and Zhao, S. (2013). Japanese encephalitis virus infects porcine kidney epithelial PK15 cells via clathrin- and cholesterol-dependent endocytosis. Virol. J., 10.","DOI":"10.1186\/1743-422X-10-258"},{"key":"ref_196","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1099\/jgv.0.000015","article-title":"Heat shock cognate protein 70 isoform D is required for clathrin-dependent endocytosis of Japanese encephalitis virus in C6\/36 cells","volume":"96","author":"Chuang","year":"2015","journal-title":"J. Gen. Virol."},{"key":"ref_197","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1111\/j.1471-4159.2010.06951.x","article-title":"Critical role of lipid rafts in virus entry and activation of phosphoinositide 3\u2032 kinase\/Akt signaling during early stages of Japanese encephalitis virus infection in neural stem\/progenitor cells","volume":"115","author":"Das","year":"2010","journal-title":"J. Neurochem."},{"key":"ref_198","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1099\/vir.0.18883-0","article-title":"Interference in Japanese encephalitis virus infection of Vero cells by a cationic amphiphilic drug, chlorpromazine","volume":"84","author":"Nawa","year":"2003","journal-title":"J. Gen. Virol."},{"key":"ref_199","doi-asserted-by":"crossref","unstructured":"Ang, F., Wong, A.P., Ng, M.M., and Chu, J.J. (2010). Small interference RNA profiling reveals the essential role of human membrane trafficking genes in mediating the infectious entry of dengue virus. Virol. J., 7.","DOI":"10.1186\/1743-422X-7-24"},{"key":"ref_200","doi-asserted-by":"crossref","unstructured":"Suksanpaisan, L., Susantad, T., and Smith, D.R. (2009). Characterization of dengue virus entry into HepG2 cells. J. Biomed. Sci., 16.","DOI":"10.1186\/1423-0127-16-17"},{"key":"ref_201","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1128\/JVI.01399-12","article-title":"Japanese encephalitis virus infects neuronal cells through a clathrin-independent endocytic mechanism","volume":"87","author":"Kalia","year":"2013","journal-title":"J. Virol."},{"key":"ref_202","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.2217\/fmb-2016-0002","article-title":"Caveolin-1-mediated Japanese encephalitis virus entry requires a two-step regulation of actin reorganization","volume":"11","author":"Xu","year":"2016","journal-title":"Future Microbiol."},{"key":"ref_203","doi-asserted-by":"crossref","first-page":"13407","DOI":"10.1128\/JVI.00903-12","article-title":"Japanese encephalitis virus enters rat neuroblastoma cells via a pH-dependent, dynamin and caveola-mediated endocytosis pathway","volume":"86","author":"Zhu","year":"2012","journal-title":"J. Virol."},{"key":"ref_204","doi-asserted-by":"crossref","unstructured":"Piccini, L.E., Castilla, V., and Damonte, E.B. (2015). Dengue-3 virus entry into Vero cells: Role of clathrin-mediated endocytosis in the outcome of infection. PLoS ONE, 10.","DOI":"10.1371\/journal.pone.0140824"},{"key":"ref_205","doi-asserted-by":"crossref","unstructured":"Acosta, E.G., Castilla, V., and Damonte, E.B. (2012). Differential requirements in endocytic trafficking for penetration of dengue virus. PLoS ONE, 7.","DOI":"10.1371\/journal.pone.0044835"},{"key":"ref_206","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.virusres.2014.02.011","article-title":"Changes in antiviral susceptibility to entry inhibitors and endocytic uptake of dengue-2 virus serially passaged in Vero or C6\/36 cells","volume":"184","author":"Acosta","year":"2014","journal-title":"Virus Res."},{"key":"ref_207","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1128\/jvi.69.2.695-700.1995","article-title":"Oligomeric rearrangement of tick-borne encephalitis virus envelope proteins induced by an acidic pH","volume":"69","author":"Allison","year":"1995","journal-title":"J. Virol."},{"key":"ref_208","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1038\/sj.emboj.7600064","article-title":"Structure of a flavivirus envelope glycoprotein in its low-pH-induced membrane fusion conformation","volume":"23","author":"Bressanelli","year":"2004","journal-title":"EMBO J."},{"key":"ref_209","doi-asserted-by":"crossref","first-page":"5730","DOI":"10.1128\/JVI.00170-10","article-title":"In vitro reconstitution reveals key intermediate states of trimer formation by the dengue virus membrane fusion protein","volume":"84","author":"Liao","year":"2010","journal-title":"J. Virol."},{"key":"ref_210","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1038\/nature02165","article-title":"Structure of the dengue virus envelope protein after membrane fusion","volume":"427","author":"Modis","year":"2004","journal-title":"Nature"},{"key":"ref_211","doi-asserted-by":"crossref","first-page":"4338","DOI":"10.1128\/JVI.02574-08","article-title":"Crystal structure of dengue virus type 1 envelope protein in the postfusion conformation and its implications for membrane fusion","volume":"83","author":"Nayak","year":"2009","journal-title":"J. Virol."},{"key":"ref_212","doi-asserted-by":"crossref","first-page":"3784","DOI":"10.1128\/JVI.76.8.3784-3790.2002","article-title":"Membrane interactions of the tick-borne encephalitis virus fusion protein E at low pH","volume":"76","author":"Stiasny","year":"2002","journal-title":"J. Virol."},{"key":"ref_213","doi-asserted-by":"crossref","unstructured":"Stiasny, K., Kossl, C., Lepault, J., Rey, F.A., and Heinz, F.X. (2007). Characterization of a structural intermediate of flavivirus membrane fusion. PLoS Pathog., 3.","DOI":"10.1371\/journal.ppat.0030020"},{"key":"ref_214","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1006\/viro.1999.0172","article-title":"Membrane fusion activity of tick-borne encephalitis virus and recombinant subviral particles in a liposomal model system","volume":"269","author":"Corver","year":"2000","journal-title":"Virology"},{"key":"ref_215","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1006\/viro.1993.1469","article-title":"Differences between cell membrane fusion activities of two dengue type-1 isolates reflect modifications of viral structure","volume":"196","author":"Despres","year":"1993","journal-title":"Virology"},{"key":"ref_216","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1099\/0022-1317-67-1-157","article-title":"pH-dependent fusion between the flavivirus West Nile and liposomal model membranes","volume":"67","author":"Gollins","year":"1986","journal-title":"J. Gen. Virol."},{"key":"ref_217","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1006\/viro.1993.1252","article-title":"Selection and partial characterization of dengue 2 virus mutants that induce fusion at elevated pH","volume":"194","author":"Guirakhoo","year":"1993","journal-title":"Virology"},{"key":"ref_218","doi-asserted-by":"crossref","first-page":"2085","DOI":"10.1099\/0022-1317-77-9-2085","article-title":"A mouse-attenuated envelope protein variant of Murray Valley encephalitis virus with altered fusion activity","volume":"77","author":"McMinn","year":"1996","journal-title":"J. Gen. Virol."},{"key":"ref_219","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1099\/0022-1317-71-8-1845","article-title":"Low pH-induced cell fusion in flavivirus-infected Aedes albopictus cell cultures","volume":"71","author":"Randolph","year":"1990","journal-title":"J. Gen. Virol."},{"key":"ref_220","doi-asserted-by":"crossref","first-page":"7856","DOI":"10.1128\/JVI.77.14.7856-7862.2003","article-title":"Involvement of lipids in different steps of the flavivirus fusion mechanism","volume":"77","author":"Stiasny","year":"2003","journal-title":"J. Virol."},{"key":"ref_221","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/0168-1702(89)90095-6","article-title":"Flaviviruses can mediate fusion from without in Aedes albopictus mosquito cell cultures","volume":"12","author":"Summers","year":"1989","journal-title":"Virus Res."},{"key":"ref_222","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.chom.2009.04.001","article-title":"Pathogenesis of flavivirus infections: Using and abusing the host cell","volume":"5","author":"Mazzon","year":"2009","journal-title":"Cell Host Microbe"},{"key":"ref_223","doi-asserted-by":"crossref","first-page":"10438","DOI":"10.1128\/JVI.00986-10","article-title":"The endoplasmic reticulum provides the membrane platform for biogenesis of the flavivirus replication complex","volume":"84","author":"Gillespie","year":"2010","journal-title":"J. Virol."},{"key":"ref_224","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1016\/j.cell.2010.03.050","article-title":"Viral reorganization of the secretory pathway generates distinct organelles for RNA replication","volume":"141","author":"Hsu","year":"2010","journal-title":"Cell"},{"key":"ref_225","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.chom.2009.03.007","article-title":"Composition and three-dimensional architecture of the dengue virus replication and assembly sites","volume":"5","author":"Welsch","year":"2009","journal-title":"Cell Host Microbe"},{"key":"ref_226","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1038\/nrmicro.2017.170","article-title":"Rewiring cellular networks by members of the Flaviviridae family","volume":"16","author":"Neufeldt","year":"2018","journal-title":"Nat. Rev. Microbiol."},{"key":"ref_227","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1016\/j.virol.2015.02.029","article-title":"Ultrastructure of the replication sites of positive-strand RNA viruses","volume":"479\u2013480","author":"Harak","year":"2015","journal-title":"Virology"},{"key":"ref_228","doi-asserted-by":"crossref","unstructured":"Brand, C., Bisaillon, M., and Geiss, B.J. (2017). Organization of the flavivirus RNA replicase complex. Wiley Interdiscip. Rev. RNA, 8.","DOI":"10.1002\/wrna.1437"},{"key":"ref_229","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.antiviral.2009.11.009","article-title":"Structure and functionality in flavivirus NS-proteins: Perspectives for drug design","volume":"87","author":"Bollati","year":"2010","journal-title":"Antivir. Res."},{"key":"ref_230","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.coviro.2014.09.011","article-title":"Regulation of flavivirus RNA synthesis and replication","volume":"9","author":"Selisko","year":"2014","journal-title":"Curr. Opin. Virol."},{"key":"ref_231","doi-asserted-by":"crossref","first-page":"1672","DOI":"10.1128\/jvi.67.3.1672-1675.1993","article-title":"Proper maturation of the Japanese encephalitis virus envelope glycoprotein requires cosynthesis with the premembrane protein","volume":"67","author":"Konishi","year":"1993","journal-title":"J. Virol."},{"key":"ref_232","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.1126\/science.1153263","article-title":"The flavivirus precursor membrane-envelope protein complex: Structure and maturation","volume":"319","author":"Li","year":"2008","journal-title":"Science"},{"key":"ref_233","doi-asserted-by":"crossref","first-page":"2604","DOI":"10.1093\/emboj\/cdg270","article-title":"Structures of immature flavivirus particles","volume":"22","author":"Zhang","year":"2003","journal-title":"EMBO J."},{"key":"ref_234","doi-asserted-by":"crossref","first-page":"6141","DOI":"10.1128\/JVI.00037-07","article-title":"Structure of immature West Nile virus","volume":"81","author":"Zhang","year":"2007","journal-title":"J. Virol."},{"key":"ref_235","doi-asserted-by":"crossref","first-page":"5480","DOI":"10.1128\/JVI.76.11.5480-5491.2002","article-title":"Folding and dimerization of tick-borne encephalitis virus envelope proteins prM and E in the endoplasmic reticulum","volume":"76","author":"Lorenz","year":"2002","journal-title":"J. Virol."},{"key":"ref_236","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1099\/vir.0.18723-0","article-title":"Cleavage of protein prM is necessary for infection of BHK-21 cells by tick-borne encephalitis virus","volume":"84","author":"Elshuber","year":"2003","journal-title":"J. Gen. Virol."},{"key":"ref_237","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1099\/0022-1317-72-6-1323","article-title":"Fusion activity of flaviviruses: Comparison of mature and immature (prM-containing) tick-borne encephalitis virions","volume":"72","author":"Guirakhoo","year":"1991","journal-title":"J. Gen. Virol."},{"key":"ref_238","doi-asserted-by":"crossref","first-page":"12101","DOI":"10.1128\/JVI.01637-09","article-title":"Association of the pr peptides with dengue virus at acidic pH blocks membrane fusion","volume":"83","author":"Yu","year":"2009","journal-title":"J. Virol."},{"key":"ref_239","doi-asserted-by":"crossref","first-page":"1834","DOI":"10.1126\/science.1153264","article-title":"Structure of the immature dengue virus at low pH primes proteolytic maturation","volume":"319","author":"Yu","year":"2008","journal-title":"Science"},{"key":"ref_240","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1016\/j.str.2004.06.019","article-title":"Conformational changes of the flavivirus E glycoprotein","volume":"12","author":"Zhang","year":"2004","journal-title":"Structure"},{"key":"ref_241","doi-asserted-by":"crossref","first-page":"7210","DOI":"10.1128\/JVI.03690-13","article-title":"Mechanism and significance of cell type-dependent neutralization of flaviviruses","volume":"88","author":"Mukherjee","year":"2014","journal-title":"J. Virol."},{"key":"ref_242","doi-asserted-by":"crossref","unstructured":"Nelson, S., Jost, C.A., Xu, Q., Ess, J., Martin, J.E., Oliphant, T., Whitehead, S.S., Durbin, A.P., Graham, B.S., and Diamond, M.S. (2008). Maturation of West Nile virus modulates sensitivity to antibody-mediated neutralization. PLoS Pathog., 4.","DOI":"10.1371\/journal.ppat.1000060"},{"key":"ref_243","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.virol.2017.12.032","article-title":"The Zika virus envelope protein glycan loop regulates virion antigenicity","volume":"515","author":"Goo","year":"2018","journal-title":"Virology"},{"key":"ref_244","doi-asserted-by":"crossref","first-page":"12067","DOI":"10.1128\/JVI.05559-11","article-title":"The infectivity of prM-containing partially mature West Nile virus does not require the activity of cellular furin-like proteases","volume":"85","author":"Mukherjee","year":"2011","journal-title":"J. Virol."},{"key":"ref_245","doi-asserted-by":"crossref","first-page":"33149","DOI":"10.1074\/jbc.M114.610428","article-title":"Highly conserved residues in the helical domain of dengue virus type 1 precursor membrane protein are involved in assembly, precursor membrane (prM) protein cleavage, and entry","volume":"289","author":"Hsieh","year":"2014","journal-title":"J. Biol. Chem."},{"key":"ref_246","doi-asserted-by":"crossref","first-page":"3448","DOI":"10.1128\/JVI.79.6.3448-3458.2005","article-title":"Nuclear localization of Japanese encephalitis virus core protein enhances viral replication","volume":"79","author":"Mori","year":"2005","journal-title":"J. Virol."},{"key":"ref_247","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1099\/vir.0.83264-0","article-title":"Multiple regions in dengue virus capsid protein contribute to nuclear localization during virus infection","volume":"89","author":"Sangiambut","year":"2008","journal-title":"J. Gen. Virol."},{"key":"ref_248","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.virusres.2009.11.012","article-title":"Nuclear localization of dengue virus capsid protein is required for DAXX interaction and apoptosis","volume":"147","author":"Netsawang","year":"2010","journal-title":"Virus Res."},{"key":"ref_249","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1016\/j.micinf.2010.04.005","article-title":"West Nile virus capsid protein interaction with importin and HDM2 protein is regulated by protein kinase C-mediated phosphorylation","volume":"12","author":"Bhuvanakantham","year":"2010","journal-title":"Microbes Infect."},{"key":"ref_250","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.bbrc.2009.08.108","article-title":"Specific interaction of capsid protein and importin-\u03b1\/\u03b2 influences West Nile virus production","volume":"389","author":"Bhuvanakantham","year":"2009","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"ref_251","doi-asserted-by":"crossref","first-page":"5451","DOI":"10.1128\/JVI.01982-05","article-title":"Nuclear localization of flavivirus RNA synthesis in infected cells","volume":"80","author":"Uchil","year":"2006","journal-title":"J. Virol."},{"key":"ref_252","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1099\/0022-1317-73-5-1125","article-title":"Monoclonal antibodies identify the NS5 yellow fever virus non-structural protein in the nuclei of infected cells","volume":"73","author":"Buckley","year":"1992","journal-title":"J. Gen. Virol."},{"key":"ref_253","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1006\/bbrc.1999.0370","article-title":"The 37-amino-acid interdomain of dengue virus NS5 protein contains a functional NLS and inhibitory CK2 site","volume":"257","author":"Forwood","year":"1999","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"ref_254","doi-asserted-by":"crossref","unstructured":"Tay, M.Y., Smith, K., Ng, I.H., Chan, K.W., Zhao, Y., Ooi, E.E., Lescar, J., Luo, D., Jans, D.A., and Forwood, J.K. (2016). The C-terminal 18 amino acid region of dengue virus NS5 regulates its subcellular localization and contains a conserved arginine residue essential for infectious virus production. PLoS Pathog., 12.","DOI":"10.1371\/journal.ppat.1005886"},{"key":"ref_255","doi-asserted-by":"crossref","first-page":"4545","DOI":"10.1128\/JVI.03083-12","article-title":"Nuclear localization of dengue virus nonstructural protein 5 does not strictly correlate with efficient viral RNA replication and inhibition of type I interferon signaling","volume":"87","author":"Kumar","year":"2013","journal-title":"J. Virol."},{"key":"ref_256","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1111\/j.1600-0854.2007.00579.x","article-title":"Nuclear localization of dengue virus nonstructural protein 5 through its importin \u03b1\/\u03b2-recognized nuclear localization sequences is integral to viral infection","volume":"8","author":"Pryor","year":"2007","journal-title":"Traffic"},{"key":"ref_257","doi-asserted-by":"crossref","first-page":"36399","DOI":"10.1074\/jbc.M204977200","article-title":"The interdomain region of dengue NS5 protein that binds to the viral helicase NS3 contains independently functional importin \u03b21 and importin \u03b1\/\u03b2-recognized nuclear localization signals","volume":"277","author":"Brooks","year":"2002","journal-title":"J. Biol. Chem."},{"key":"ref_258","doi-asserted-by":"crossref","unstructured":"Lopez-Denman, A.J., and Mackenzie, J.M. (2017). The IMPORTance of the nucleus during flavivirus replication. Viruses, 9.","DOI":"10.3390\/v9010014"},{"key":"ref_259","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/j.cell.2006.02.007","article-title":"Virus entry: Open sesame","volume":"124","author":"Marsh","year":"2006","journal-title":"Cell"},{"key":"ref_260","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1126\/science.1094823","article-title":"How viruses enter animal cells","volume":"304","author":"Smith","year":"2004","journal-title":"Science"},{"key":"ref_261","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1080\/13550280152403236","article-title":"Virus receptors in the human central nervous system","volume":"7","author":"Schweighardt","year":"2001","journal-title":"J. Neurovirol."},{"key":"ref_262","doi-asserted-by":"crossref","first-page":"3701","DOI":"10.2174\/1381612043382729","article-title":"Virus attachment and entry offer numerous targets for antiviral therapy","volume":"10","author":"Altmeyer","year":"2004","journal-title":"Curr. Pharm. Des."},{"key":"ref_263","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1021\/acsinfecdis.5b00066","article-title":"Flavivirus entry inhibitors","volume":"1","author":"Wang","year":"2015","journal-title":"ACS Infect. Dis."},{"key":"ref_264","doi-asserted-by":"crossref","first-page":"5605","DOI":"10.1128\/JVI.73.7.5605-5612.1999","article-title":"Mapping of functional elements in the stem-anchor region of tick-borne encephalitis virus envelope protein E","volume":"73","author":"Allison","year":"1999","journal-title":"J. Virol."},{"key":"ref_265","doi-asserted-by":"crossref","first-page":"8142","DOI":"10.1128\/jvi.70.11.8142-8147.1996","article-title":"Structural requirements for low-pH-induced rearrangements in the envelope glycoprotein of tick-borne encephalitis virus","volume":"70","author":"Stiasny","year":"1996","journal-title":"J. Virol."},{"key":"ref_266","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1038\/nsb990","article-title":"Visualization of membrane protein domains by cryo-electron microscopy of dengue virus","volume":"10","author":"Zhang","year":"2003","journal-title":"Nat. Struct. Biol."},{"key":"ref_267","doi-asserted-by":"crossref","first-page":"4268","DOI":"10.1128\/JVI.75.9.4268-4275.2001","article-title":"Mutational evidence for an internal fusion peptide in flavivirus envelope protein E","volume":"75","author":"Allison","year":"2001","journal-title":"J. Virol."},{"key":"ref_268","doi-asserted-by":"crossref","first-page":"13097","DOI":"10.1128\/JVI.76.24.13097-13100.2002","article-title":"Identification of neutralizing epitopes within structural domain III of the West Nile virus envelope protein","volume":"76","author":"Beasley","year":"2002","journal-title":"J. Virol."},{"key":"ref_269","doi-asserted-by":"crossref","first-page":"4002","DOI":"10.1128\/JVI.75.8.4002-4007.2001","article-title":"Biophysical characterization and vector-specific antagonist activity of domain III of the tick-borne flavivirus envelope protein","volume":"75","author":"Bhardwaj","year":"2001","journal-title":"J. Virol."},{"key":"ref_270","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1099\/vir.0.80411-0","article-title":"Inhibition of West Nile virus entry by using a recombinant domain III from the envelope glycoprotein","volume":"86","author":"Chu","year":"2005","journal-title":"J. Gen. Virol."},{"key":"ref_271","doi-asserted-by":"crossref","first-page":"7769","DOI":"10.1128\/JVI.75.16.7769-7773.2001","article-title":"Monoclonal antibodies that bind to domain III of dengue virus E glycoprotein are the most efficient blockers of virus adsorption to Vero cells","volume":"75","author":"Crill","year":"2001","journal-title":"J. Virol."},{"key":"ref_272","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1016\/j.vaccine.2004.03.069","article-title":"Dengue virus: Molecular basis of cell entry and pathogenesis, 25\u201327 June 2003, Vienna, Austria","volume":"23","author":"Halstead","year":"2005","journal-title":"Vaccine"},{"key":"ref_273","doi-asserted-by":"crossref","first-page":"12400","DOI":"10.1073\/pnas.0603488103","article-title":"West Nile virus in complex with the Fab fragment of a neutralizing monoclonal antibody","volume":"103","author":"Kaufmann","year":"2006","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_274","doi-asserted-by":"crossref","first-page":"4901","DOI":"10.1128\/JVI.76.10.4901-4911.2002","article-title":"Mechanism of virulence attenuation of glycosaminoglycan-binding variants of Japanese encephalitis virus and Murray Valley encephalitis virus","volume":"76","author":"Lee","year":"2002","journal-title":"J. Virol."},{"key":"ref_275","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1074\/jbc.M506614200","article-title":"Quantifying the specific binding between West Nile virus envelope domain III protein and the cellular receptor \u03b1v\u03b23 integrin","volume":"281","author":"Lee","year":"2006","journal-title":"J. Biol. Chem."},{"key":"ref_276","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.virol.2005.02.011","article-title":"Differential expression of domain III neutralizing epitopes on the envelope proteins of West Nile virus strains","volume":"335","author":"Li","year":"2005","journal-title":"Virology"},{"key":"ref_277","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.chom.2007.03.002","article-title":"The stoichiometry of antibody-mediated neutralization and enhancement of West Nile virus infection","volume":"1","author":"Pierson","year":"2007","journal-title":"Cell Host Microbe"},{"key":"ref_278","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1038\/375291a0","article-title":"The envelope glycoprotein from tick-borne encephalitis virus at 2 A resolution","volume":"375","author":"Rey","year":"1995","journal-title":"Nature"},{"key":"ref_279","doi-asserted-by":"crossref","first-page":"9557","DOI":"10.1128\/JVI.00080-06","article-title":"Cryptic properties of a cluster of dominant flavivirus cross-reactive antigenic sites","volume":"80","author":"Stiasny","year":"2006","journal-title":"J. Virol."},{"key":"ref_280","doi-asserted-by":"crossref","first-page":"12816","DOI":"10.1128\/JVI.00432-07","article-title":"Type- and subcomplex-specific neutralizing antibodies against domain III of dengue virus type 2 envelope protein recognize adjacent epitopes","volume":"81","author":"Austin","year":"2007","journal-title":"J. Virol."},{"key":"ref_281","doi-asserted-by":"crossref","first-page":"46007","DOI":"10.1074\/jbc.M307776200","article-title":"Structural basis of a flavivirus recognized by its neutralizing antibody: Solution structure of the domain III of the Japanese encephalitis virus envelope protein","volume":"278","author":"Wu","year":"2003","journal-title":"J. Biol. Chem."},{"key":"ref_282","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.virol.2009.10.027","article-title":"The dengue virus type 2 envelope protein fusion peptide is essential for membrane fusion","volume":"396","author":"Huang","year":"2010","journal-title":"Virology"},{"key":"ref_283","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.chom.2010.08.007","article-title":"The human immune response to dengue virus is dominated by highly cross-reactive antibodies endowed with neutralizing and enhancing activity","volume":"8","author":"Beltramello","year":"2010","journal-title":"Cell Host Microbe"},{"key":"ref_284","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1099\/vir.0.040238-0","article-title":"Mutation analysis of the cross-reactive epitopes of Japanese encephalitis virus envelope glycoprotein","volume":"93","author":"Chiou","year":"2012","journal-title":"J. Gen. Virol."},{"key":"ref_285","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.rvsc.2016.12.007","article-title":"Integrin \u03b1v\u03b23 promotes infection by Japanese encephalitis virus","volume":"111","author":"Fan","year":"2017","journal-title":"Res. Vet. Sci."},{"key":"ref_286","doi-asserted-by":"crossref","first-page":"2023","DOI":"10.1007\/s00705-014-2042-2","article-title":"Distinct usage of three C-type lectins by Japanese encephalitis virus: DC-SIGN, DC-SIGNR, and LSECtin","volume":"159","author":"Shimojima","year":"2014","journal-title":"Arch. Virol."},{"key":"ref_287","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.virol.2015.11.006","article-title":"DC-SIGN as an attachment factor mediates Japanese encephalitis virus infection of human dendritic cells via interaction with a single high-mannose residue of viral E glycoprotein","volume":"488","author":"Wang","year":"2016","journal-title":"Virology"},{"key":"ref_288","doi-asserted-by":"crossref","first-page":"54533","DOI":"10.1074\/jbc.M410208200","article-title":"Interaction of West Nile virus with \u03b1v\u03b23 integrin mediates virus entry into cells","volume":"279","author":"Chu","year":"2004","journal-title":"J. Biol. Chem."},{"key":"ref_289","doi-asserted-by":"crossref","first-page":"7692","DOI":"10.1128\/JVI.75.16.7692-7702.2001","article-title":"Attenuation of Murray Valley encephalitis virus by site-directed mutagenesis of the hinge and putative receptor-binding regions of the envelope protein","volume":"75","author":"Hurrelbrink","year":"2001","journal-title":"J. Virol."},{"key":"ref_290","doi-asserted-by":"crossref","first-page":"8867","DOI":"10.1128\/JVI.74.19.8867-8875.2000","article-title":"Substitutions at the putative receptor-binding site of an encephalitic flavivirus alter virulence and host cell tropism and reveal a role for glycosaminoglycans in entry","volume":"74","author":"Lee","year":"2000","journal-title":"J. Virol."},{"key":"ref_291","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/0042-6822(90)90029-Q","article-title":"Host cell selection of Murray Valley encephalitis virus variants altered at an RGD sequence in the envelope protein and in mouse virulence","volume":"176","author":"Lobigs","year":"1990","journal-title":"Virology"},{"key":"ref_292","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1006\/viro.1999.0026","article-title":"Mutagenesis of the RGD motif in the yellow fever virus 17D envelope protein","volume":"265","author":"Corver","year":"1999","journal-title":"Virology"},{"key":"ref_293","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1084\/jem.20051352","article-title":"Live attenuated yellow fever 17D infects human DCs and allows for presentation of endogenous and recombinant T cell epitopes","volume":"202","author":"Longman","year":"2005","journal-title":"J. Exp. Med."},{"key":"ref_294","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1016\/j.celrep.2017.10.016","article-title":"Functional analysis of glycosylation of Zika virus envelope protein","volume":"21","author":"Shan","year":"2017","journal-title":"Cell Rep."},{"key":"ref_295","doi-asserted-by":"crossref","first-page":"5668","DOI":"10.1128\/JVI.00293-15","article-title":"Structure-based mutational analysis of several sites in the E protein: Implications for understanding the entry mechanism of Japanese encephalitis virus","volume":"89","author":"Liu","year":"2015","journal-title":"J. Virol."},{"key":"ref_296","doi-asserted-by":"crossref","first-page":"2337","DOI":"10.1128\/JVI.06072-11","article-title":"Crystal structure of the Japanese encephalitis virus envelope protein","volume":"86","author":"Luca","year":"2012","journal-title":"J. Virol."},{"key":"ref_297","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1002\/jmv.20406","article-title":"Fitness of Japanese encephalitis virus to Neuro-2a cells is determined by interactions of the viral envelope protein with highly sulfated glycosaminoglycans on the cell surface","volume":"76","author":"Chiou","year":"2005","journal-title":"J. Med. Virol."},{"key":"ref_298","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1006\/viro.2001.0986","article-title":"Highly sulfated forms of heparin sulfate are involved in Japanese encephalitis virus infection","volume":"286","author":"Su","year":"2001","journal-title":"Virology"},{"key":"ref_299","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1002\/jmv.20025","article-title":"Differential binding efficiency between the envelope protein of Japanese encephalitis virus variants and heparan sulfate on the cell surface","volume":"72","author":"Liu","year":"2004","journal-title":"J. Med. Virol."},{"key":"ref_300","doi-asserted-by":"crossref","first-page":"8271","DOI":"10.1128\/JVI.78.15.8271-8280.2004","article-title":"Common E protein determinants for attenuation of glycosaminoglycan-binding variants of Japanese encephalitis and West Nile viruses","volume":"78","author":"Lee","year":"2004","journal-title":"J. Virol."},{"key":"ref_301","doi-asserted-by":"crossref","first-page":"12510","DOI":"10.1128\/JVI.00458-08","article-title":"Neuroadapted yellow fever virus strain 17D: A charged locus in domain III of the E protein governs heparin binding activity and neuroinvasiveness in the SCID mouse model","volume":"82","author":"Nickells","year":"2008","journal-title":"J. Virol."},{"key":"ref_302","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1006\/viro.2001.1232","article-title":"Heparan sulfate-mediated binding of infectious dengue virus type 2 and yellow fever virus","volume":"292","author":"Germi","year":"2002","journal-title":"Virology"},{"key":"ref_303","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1053\/jhep.2000.18713","article-title":"Heparan sulfate proteoglycans initiate dengue virus infection of hepatocytes","volume":"32","author":"Hilgard","year":"2000","journal-title":"Hepatology"},{"key":"ref_304","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/S0042-6822(02)00097-1","article-title":"Role of heparan sulfate for attachment and entry of tick-borne encephalitis virus","volume":"308","author":"Kroschewski","year":"2003","journal-title":"Virology"},{"key":"ref_305","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1099\/vir.0.037853-0","article-title":"Dengue virus strain DEN2 16681 utilizes a specific glycochain of syndecan-2 proteoglycan as a receptor","volume":"93","author":"Okamoto","year":"2012","journal-title":"J. Gen. Virol."},{"key":"ref_306","doi-asserted-by":"crossref","first-page":"5627","DOI":"10.1128\/JVI.75.12.5627-5637.2001","article-title":"Adaptation of tick-borne encephalitis virus to BHK-21 cells results in the formation of multiple heparan sulfate binding sites in the envelope protein and attenuation in vivo","volume":"75","author":"Mandl","year":"2001","journal-title":"J. Virol."},{"key":"ref_307","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.virol.2013.03.011","article-title":"Mutation of the dengue virus type 2 envelope protein heparan sulfate binding sites or the domain III lateral ridge blocks replication in Vero cells prior to membrane fusion","volume":"441","author":"Roehrig","year":"2013","journal-title":"Virology"},{"key":"ref_308","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1099\/vir.0.037317-0","article-title":"Residues in domain III of the dengue virus envelope glycoprotein involved in cell-surface glycosaminoglycan binding","volume":"93","author":"Watterson","year":"2012","journal-title":"J. Gen. Virol."},{"key":"ref_309","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1021\/acs.biochem.6b01056","article-title":"Interaction of Zika virus envelope protein with glycosaminoglycans","volume":"56","author":"Kim","year":"2017","journal-title":"Biochemistry"},{"key":"ref_310","doi-asserted-by":"crossref","first-page":"7818","DOI":"10.1128\/JVI.75.17.7818-7827.2001","article-title":"Identification of a putative coreceptor on Vero cells that participates in dengue 4 virus infection","volume":"75","year":"2001","journal-title":"J. Virol."},{"key":"ref_311","doi-asserted-by":"crossref","first-page":"9478","DOI":"10.1128\/JVI.05008-11","article-title":"Productive dengue virus infection of human endothelial cells is directed by heparan sulfate-containing proteoglycan receptors","volume":"85","author":"Dalrymple","year":"2011","journal-title":"J. Virol."},{"key":"ref_312","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1006\/viro.1999.9633","article-title":"Analysis of the steps involved in dengue virus entry into host cells","volume":"257","author":"Hung","year":"1999","journal-title":"Virology"},{"key":"ref_313","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1111\/brv.12034","article-title":"Glycosaminoglycans in infectious disease","volume":"88","author":"Kamhi","year":"2013","journal-title":"Biol. Rev. Camb. Philos. Soc."},{"key":"ref_314","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0968-0004(03)00031-8","article-title":"Heparan sulfate proteoglycan as a plasma membrane carrier","volume":"28","author":"Belting","year":"2003","journal-title":"Trends Biochem. Sci."},{"key":"ref_315","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.vaccine.2007.10.047","article-title":"Phenotypic changes in the Japanese encephalitis virus after one passage in Neuro-2a cells: Generation of attenuated strains of the virus","volume":"26","author":"Chiou","year":"2007","journal-title":"Vaccine"},{"key":"ref_316","doi-asserted-by":"crossref","first-page":"2229","DOI":"10.3390\/molecules20022229","article-title":"Human lectins and their roles in viral infections","volume":"20","author":"Mason","year":"2015","journal-title":"Molecules"},{"key":"ref_317","doi-asserted-by":"crossref","first-page":"54","DOI":"10.3109\/08830185.2013.834897","article-title":"DC-SIGN, DC-SIGNR and LSECtin: C-type lectins for infection","volume":"33","author":"Zhang","year":"2014","journal-title":"Int. Rev. Immunol."},{"key":"ref_318","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/S0092-8674(00)80694-7","article-title":"DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells","volume":"100","author":"Geijtenbeek","year":"2000","journal-title":"Cell"},{"key":"ref_319","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/S0092-8674(00)80693-5","article-title":"Identification of DC-SIGN, a novel dendritic cell-specific ICAM-3 receptor that supports primary immune responses","volume":"100","author":"Geijtenbeek","year":"2000","journal-title":"Cell"},{"key":"ref_320","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1016\/S0002-9440(10)63717-0","article-title":"Dynamic populations of dendritic cell-specific ICAM-3 grabbing nonintegrin-positive immature dendritic cells and liver\/lymph node-specific ICAM-3 grabbing nonintegrin-positive endothelial cells in the outer zones of the paracortex of human lymph nodes","volume":"164","author":"Engering","year":"2004","journal-title":"Am. J. Pathol."},{"key":"ref_321","doi-asserted-by":"crossref","first-page":"2670","DOI":"10.1073\/pnas.051631398","article-title":"DC-SIGNR, a DC-SIGN homologue expressed in endothelial cells, binds to human and simian immunodeficiency viruses and activates infection in trans","volume":"98","author":"Pohlmann","year":"2001","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_322","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1084\/jem.193.6.671","article-title":"A dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN)-related protein is highly expressed on human liver sinusoidal endothelial cells and promotes HIV-1 infection","volume":"193","author":"Bashirova","year":"2001","journal-title":"J. Exp. Med."},{"key":"ref_323","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1007\/s00109-008-0350-2","article-title":"DC-SIGN and L-SIGN: The SIGNs for infection","volume":"86","author":"Khoo","year":"2008","journal-title":"J. Mol. Med."},{"key":"ref_324","doi-asserted-by":"crossref","first-page":"37183","DOI":"10.1074\/jbc.M605429200","article-title":"The location of asparagine-linked glycans on West Nile virions controls their interactions with CD209 (dendritic cell-specific ICAM-3 grabbing nonintegrin)","volume":"281","author":"Davis","year":"2006","journal-title":"J. Biol. Chem."},{"key":"ref_325","doi-asserted-by":"crossref","first-page":"7136","DOI":"10.1128\/JVI.00116-07","article-title":"Essential role of dengue virus envelope protein N-glycosylation at asparagine-67 during viral propagation","volume":"81","author":"Mondotte","year":"2007","journal-title":"J. Virol."},{"key":"ref_326","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1093\/infdis\/jir173","article-title":"Lectin switching during dengue virus infection","volume":"203","author":"Dejnirattisai","year":"2011","journal-title":"J. Infect. Dis."},{"key":"ref_327","doi-asserted-by":"crossref","first-page":"23698","DOI":"10.1074\/jbc.M504337200","article-title":"Dendritic cell-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN)-mediated enhancement of dengue virus infection is independent of DC-SIGN internalization signals","volume":"280","author":"Lozach","year":"2005","journal-title":"J. Biol. Chem."},{"key":"ref_328","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1111\/tra.12469","article-title":"Beyond attachment: Roles of DC-SIGN in dengue virus infection","volume":"18","author":"Liu","year":"2017","journal-title":"Traffic"},{"key":"ref_329","doi-asserted-by":"crossref","unstructured":"Shah, M., Wadood, A., Rahman, Z., and Husnain, T. (2013). Interaction and inhibition of dengue envelope glycoprotein with mammalian receptor DC-sign, an in-silico approach. PLoS ONE, 8.","DOI":"10.1371\/journal.pone.0059211"},{"key":"ref_330","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.coviro.2017.06.009","article-title":"Flavivirus structural heterogeneity: Implications for cell entry","volume":"24","author":"Rey","year":"2017","journal-title":"Curr. Opin. Virol."},{"key":"ref_331","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.coviro.2012.02.011","article-title":"Degrees of maturity: The complex structure and biology of flaviviruses","volume":"2","author":"Pierson","year":"2012","journal-title":"Curr. Opin. Virol."},{"key":"ref_332","doi-asserted-by":"crossref","first-page":"7846","DOI":"10.1128\/JVI.00789-08","article-title":"A single N-linked glycosylation site in the Japanese encephalitis virus prM protein is critical for cell type-specific prM protein biogenesis, virus particle release, and pathogenicity in mice","volume":"82","author":"Kim","year":"2008","journal-title":"J. Virol."},{"key":"ref_333","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.actatropica.2017.10.017","article-title":"Associations of DC-SIGN (CD209) promoter -336G\/A polymorphism (rs4804803) with dengue infection: A systematic review and meta-analysis","volume":"177","author":"Pabalan","year":"2018","journal-title":"Acta Trop."},{"key":"ref_334","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.antiviral.2011.10.017","article-title":"Single nucleotide polymorphism in the promoter region of the CD209 gene is associated with human predisposition to severe forms of tick-borne encephalitis","volume":"93","author":"Barkhash","year":"2012","journal-title":"Antivir. Res."},{"key":"ref_335","doi-asserted-by":"crossref","unstructured":"Miller, J.L., de Wet, B.J., Martinez-Pomares, L., Radcliffe, C.M., Dwek, R.A., Rudd, P.M., and Gordon, S. (2008). The mannose receptor mediates dengue virus infection of macrophages. PLoS Pathog., 4.","DOI":"10.1371\/annotation\/98b92fca-fa6e-4bf3-9b39-13b66b640476"},{"key":"ref_336","doi-asserted-by":"crossref","unstructured":"Chen, S.T., Liu, R.S., Wu, M.F., Lin, Y.L., Chen, S.Y., Tan, D.T., Chou, T.Y., Tsai, I.S., Li, L., and Hsieh, S.L. (2012). CLEC5A regulates Japanese encephalitis virus-induced neuroinflammation and lethality. PLoS Pathog., 8.","DOI":"10.1371\/journal.ppat.1002655"},{"key":"ref_337","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1038\/nature07013","article-title":"CLEC5A is critical for dengue virus-induced lethal disease","volume":"453","author":"Chen","year":"2008","journal-title":"Nature"},{"key":"ref_338","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1189\/jlb.0512231","article-title":"The mannose receptor","volume":"92","year":"2012","journal-title":"J. Leukoc. Biol."},{"key":"ref_339","doi-asserted-by":"crossref","first-page":"9792","DOI":"10.1073\/pnas.96.17.9792","article-title":"Myeloid DAP12-associating lectin (MDL)-1 is a cell surface receptor involved in the activation of myeloid cells","volume":"96","author":"Bakker","year":"1999","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_340","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1038\/35642","article-title":"Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells","volume":"391","author":"Lanier","year":"1998","journal-title":"Nature"},{"key":"ref_341","doi-asserted-by":"crossref","first-page":"5337","DOI":"10.1182\/blood-2006-09-048058","article-title":"The DC-SIGN-related lectin LSECtin mediates antigen capture and pathogen binding by human myeloid cells","volume":"109","author":"Colmenares","year":"2007","journal-title":"Blood"},{"key":"ref_342","doi-asserted-by":"crossref","unstructured":"Liu, K., Qian, Y., Jung, Y.S., Zhou, B., Cao, R., Shen, T., Shao, D., Wei, J., Ma, Z., and Chen, P. (2017). mosGCTL-7, a C-type lectin protein, mediates Japanese encephalitis virus infection in mosquitoes. J. Virol., 91.","DOI":"10.1128\/JVI.01348-16"},{"key":"ref_343","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1016\/j.cell.2010.07.038","article-title":"A C-type lectin collaborates with a CD45 phosphatase homolog to facilitate West Nile virus infection of mosquitoes","volume":"142","author":"Cheng","year":"2010","journal-title":"Cell"},{"key":"ref_344","doi-asserted-by":"crossref","unstructured":"Liu, Y., Zhang, F., Liu, J., Xiao, X., Zhang, S., Qin, C., Xiang, Y., Wang, P., and Cheng, G. (2014). Transmission-blocking antibodies against mosquito C-type lectins for dengue prevention. PLoS Pathog., 10.","DOI":"10.1371\/journal.ppat.1003931"},{"key":"ref_345","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1146\/annurev.iy.07.040189.002011","article-title":"The leukocyte common antigen family","volume":"7","author":"Thomas","year":"1989","journal-title":"Annu. Rev. Immunol."},{"key":"ref_346","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1084\/jem.183.4.1707","article-title":"CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation","volume":"183","author":"Byth","year":"1996","journal-title":"J. Exp. Med."},{"key":"ref_347","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1146\/annurev.iy.12.040194.000505","article-title":"CD45: An emerging role as a protein tyrosine phosphatase required for lymphocyte activation and development","volume":"12","author":"Trowbridge","year":"1994","journal-title":"Annu. Rev. Immunol."},{"key":"ref_348","doi-asserted-by":"crossref","first-page":"3829","DOI":"10.4049\/jimmunol.167.7.3829","article-title":"Developmentally regulated changes in glucosidase II association with, and carbohydrate content of, the protein tyrosine phosphatase CD45","volume":"167","author":"Baldwin","year":"2001","journal-title":"J. Immunol."},{"key":"ref_349","doi-asserted-by":"crossref","unstructured":"Luo, H., and Wang, T. (2018). Recent advances in understanding West Nile virus host immunity and viral pathogenesis. F1000Research, 7.","DOI":"10.12688\/f1000research.13362.1"},{"key":"ref_350","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.chom.2010.07.007","article-title":"Direct complement restriction of flavivirus infection requires glycan recognition by mannose-binding lectin","volume":"8","author":"Fuchs","year":"2010","journal-title":"Cell Host Microbe"},{"key":"ref_351","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/j.humimm.2016.05.006","article-title":"Mannose-binding lectin gene (MBL2) polymorphisms related to the mannose-binding lectin low levels are associated to dengue disease severity","volume":"77","author":"Figueiredo","year":"2016","journal-title":"Hum. Immunol."},{"key":"ref_352","doi-asserted-by":"crossref","first-page":"2420","DOI":"10.1016\/j.clinthera.2017.11.002","article-title":"Integrins: Integrating the biology and therapy of cell-cell interactions","volume":"39","author":"Pandolfi","year":"2017","journal-title":"Clin. Ther."},{"key":"ref_353","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/S0042-6822(03)00261-7","article-title":"Characterization of a 105-kDa plasma membrane associated glycoprotein that is involved in West Nile virus binding and infection","volume":"312","author":"Chu","year":"2003","journal-title":"Virology"},{"key":"ref_354","doi-asserted-by":"crossref","first-page":"5212","DOI":"10.1128\/JVI.00008-08","article-title":"West Nile virus entry requires cholesterol-rich membrane microdomains and is independent of \u03b1v\u03b23 integrin","volume":"82","author":"Medigeshi","year":"2008","journal-title":"J. Virol."},{"key":"ref_355","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.1099\/vir.0.052613-0","article-title":"Integrins modulate the infection efficiency of West Nile virus into cells","volume":"94","author":"Schmidt","year":"2013","journal-title":"J. Gen. Virol."},{"key":"ref_356","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1016\/j.bbamem.2008.02.012","article-title":"Membrane-associated stress proteins: More than simply chaperones","volume":"1778","author":"Horvath","year":"2008","journal-title":"Biochim. Biophys. Acta"},{"key":"ref_357","doi-asserted-by":"crossref","unstructured":"Ren, J., Ding, T., Zhang, W., Song, J., and Ma, W. (2007). Does Japanese encephalitis virus share the same cellular receptor with other mosquito-borne flaviviruses on the C6\/36 mosquito cells?. Virol. J., 4.","DOI":"10.1186\/1743-422X-4-83"},{"key":"ref_358","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.virol.2008.10.025","article-title":"Heat shock protein 70 on Neuro2a cells is a putative receptor for Japanese encephalitis virus","volume":"385","author":"Das","year":"2009","journal-title":"Virology"},{"key":"ref_359","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1099\/vir.0.034637-0","article-title":"Association of heat shock protein 70 with lipid rafts is required for Japanese encephalitis virus infection in Huh7 cells","volume":"93","author":"Zhu","year":"2012","journal-title":"J. Gen. Virol."},{"key":"ref_360","doi-asserted-by":"crossref","unstructured":"Nain, M., Mukherjee, S., Karmakar, S.P., Paton, A.W., Paton, J.C., Abdin, M.Z., Basu, A., Kalia, M., and Vrati, S. (2017). GRP78 is an important host factor for Japanese encephalitis virus entry and replication in mammalian cells. J. Virol., 91.","DOI":"10.1128\/JVI.02274-16"},{"key":"ref_361","doi-asserted-by":"crossref","first-page":"2803","DOI":"10.1099\/vir.0.033993-0","article-title":"Identification of heat-shock protein 90\u03b2 in Japanese encephalitis virus-induced secretion proteins","volume":"92","author":"Hung","year":"2011","journal-title":"J. Gen. Virol."},{"key":"ref_362","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1002\/jmv.23248","article-title":"Characterization of putative Japanese encephalitis virus receptor molecules on microglial cells","volume":"84","author":"Thongtan","year":"2012","journal-title":"J. Med. Virol."},{"key":"ref_363","doi-asserted-by":"crossref","first-page":"4557","DOI":"10.1128\/JVI.79.8.4557-4567.2005","article-title":"Heat shock protein 90 and heat shock protein 70 are components of dengue virus receptor complex in human cells","volume":"79","author":"Medina","year":"2005","journal-title":"J. Virol."},{"key":"ref_364","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1002\/jmv.20786","article-title":"Dengue virus entry into liver (HepG2) cells is independent of hsp90 and hsp70","volume":"79","author":"Thepparit","year":"2007","journal-title":"J. Med. Virol."},{"key":"ref_365","doi-asserted-by":"crossref","first-page":"283","DOI":"10.4269\/ajtmh.2007.77.283","article-title":"Evidence that the 45-kD glycoprotein, part of a putative dengue virus receptor complex in the mosquito cell line C6\/36, is a heat-shock related protein","volume":"77","author":"Mosso","year":"2007","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_366","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1007\/s00705-003-0263-x","article-title":"Identification of GRP78 (BiP) as a liver cell expressed receptor element for dengue virus serotype 2","volume":"149","author":"Jindadamrongwech","year":"2004","journal-title":"Arch. Virol."},{"key":"ref_367","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1007\/s00705-012-1596-0","article-title":"Surface proteins of C6\/36 cells involved in dengue virus 4 binding and entry","volume":"158","year":"2013","journal-title":"Arch. Virol."},{"key":"ref_368","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1016\/j.cell.2015.10.046","article-title":"Defining hsp70 subnetworks in dengue virus replication reveals key vulnerability in flavivirus infection","volume":"163","author":"Taguwa","year":"2015","journal-title":"Cell"},{"key":"ref_369","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.jviromet.2008.05.001","article-title":"Identification of dengue virus binding proteins using affinity chromatography","volume":"151","author":"Upanan","year":"2008","journal-title":"J. Virol. Methods"},{"key":"ref_370","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.antiviral.2016.03.017","article-title":"An inducible heat shock protein 70 small molecule inhibitor demonstrates anti-dengue virus activity, validating Hsp70 as a host antiviral target","volume":"130","author":"Howe","year":"2016","journal-title":"Antivir. Res."},{"key":"ref_371","doi-asserted-by":"crossref","first-page":"1358","DOI":"10.1111\/j.1462-5822.2011.01624.x","article-title":"Vimentin binding is critical for infection by the virulent strain of Japanese encephalitis virus","volume":"13","author":"Liang","year":"2011","journal-title":"Cell. Microbiol."},{"key":"ref_372","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1006\/viro.1996.0457","article-title":"Generation and characterization of organ-tropism mutants of Japanese encephalitis virus in vivo and In vitro","volume":"223","author":"Chen","year":"1996","journal-title":"Virology"},{"key":"ref_373","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1016\/j.virusres.2011.06.001","article-title":"Japanese encephalitis virus interacts with vimentin to facilitate its entry into porcine kidney cell line","volume":"160","author":"Das","year":"2011","journal-title":"Virus Res."},{"key":"ref_374","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.virol.2008.06.017","article-title":"Bovine lactoferrin inhibits Japanese encephalitis virus by binding to heparan sulfate and receptor for low density lipoprotein","volume":"379","author":"Chien","year":"2008","journal-title":"Virology"},{"key":"ref_375","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/BF01310788","article-title":"Analysis of virus-cell binding characteristics on the determination of Japanese encephalitis virus susceptibility","volume":"139","author":"Kimura","year":"1994","journal-title":"Arch. Virol."},{"key":"ref_376","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1159\/000097394","article-title":"Entry into and production of the Japanese encephalitis virus from C6\/36 cells","volume":"50","author":"Boonsanay","year":"2007","journal-title":"Intervirology"},{"key":"ref_377","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1016\/j.chom.2012.08.009","article-title":"The TIM and TAM families of phosphatidylserine receptors mediate dengue virus entry","volume":"12","author":"Meertens","year":"2012","journal-title":"Cell Host Microbe"},{"key":"ref_378","doi-asserted-by":"crossref","unstructured":"Jemielity, S., Wang, J.J., Chan, Y.K., Ahmed, A.A., Li, W., Monahan, S., Bu, X., Farzan, M., Freeman, G.J., and Umetsu, D.T. (2013). TIM-family proteins promote infection of multiple enveloped viruses through virion-associated phosphatidylserine. PLoS Pathog., 9.","DOI":"10.1371\/journal.ppat.1003232"},{"key":"ref_379","doi-asserted-by":"crossref","first-page":"4275","DOI":"10.1128\/JVI.03287-13","article-title":"Role of phosphatidylserine receptors in enveloped virus infection","volume":"88","author":"Morizono","year":"2014","journal-title":"J. Virol."},{"key":"ref_380","doi-asserted-by":"crossref","first-page":"14682","DOI":"10.1073\/pnas.1508095112","article-title":"Virion-associated phosphatidylethanolamine promotes TIM1-mediated infection by Ebola, dengue, and West Nile viruses","volume":"112","author":"Richard","year":"2015","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_381","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.celrep.2016.06.028","article-title":"Identification of Zika virus and dengue virus dependency factors using functional genomics","volume":"16","author":"Savidis","year":"2016","journal-title":"Cell Rep."},{"key":"ref_382","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.virol.2018.03.009","article-title":"Infection by Zika viruses requires the transmembrane protein AXL, endocytosis and low pH","volume":"518","author":"Persaud","year":"2018","journal-title":"Virology"},{"key":"ref_383","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.celrep.2016.12.045","article-title":"Axl mediates Zika virus entry in human glial cells and modulates innate immune responses","volume":"18","author":"Meertens","year":"2017","journal-title":"Cell Rep."},{"key":"ref_384","doi-asserted-by":"crossref","first-page":"2024","DOI":"10.1073\/pnas.1620558114","article-title":"AXL-dependent infection of human fetal endothelial cells distinguishes Zika virus from other pathogenic flaviviruses","volume":"114","author":"Richard","year":"2017","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_385","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1161\/CIRCRESAHA.116.309866","article-title":"AXL-mediated productive infection of human endothelial cells by Zika virus","volume":"119","author":"Liu","year":"2016","journal-title":"Circ. Res."},{"key":"ref_386","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/j.stem.2016.03.012","article-title":"Expression analysis highlights AXL as a candidate Zika virus entry receptor in neural stem cells","volume":"18","author":"Nowakowski","year":"2016","journal-title":"Cell Stem Cell"},{"key":"ref_387","doi-asserted-by":"crossref","first-page":"2061","DOI":"10.1099\/jgv.0.000886","article-title":"Axl is not an indispensable factor for Zika virus infection in mice","volume":"98","author":"Wang","year":"2017","journal-title":"J. Gen. Virol."},{"key":"ref_388","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1016\/j.celrep.2017.03.058","article-title":"TAM receptors are not required for Zika virus infection in mice","volume":"19","author":"Hastings","year":"2017","journal-title":"Cell Rep."},{"key":"ref_389","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1128\/JVI.01849-15","article-title":"The phosphatidylserine and phosphatidylethanolamine receptor CD300a binds dengue virus and enhances infection","volume":"90","author":"Carnec","year":"2016","journal-title":"J. Virol."},{"key":"ref_390","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.virol.2013.08.009","article-title":"The interaction between claudin-1 and dengue viral prM\/M protein for its entry","volume":"446","author":"Che","year":"2013","journal-title":"Virology"},{"key":"ref_391","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1016\/j.bbrc.2009.11.172","article-title":"Novel binding between pre-membrane protein and claudin-1 is required for efficient dengue virus entry","volume":"391","author":"Gao","year":"2010","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"ref_392","doi-asserted-by":"crossref","unstructured":"Li, Y., Kakinami, C., Li, Q., Yang, B., and Li, H. (2013). Human apolipoprotein A-I is associated with dengue virus and enhances virus infection through SR-BI. PLoS ONE, 8.","DOI":"10.1371\/journal.pone.0070390"},{"key":"ref_393","doi-asserted-by":"crossref","first-page":"12647","DOI":"10.1128\/JVI.78.22.12647-12656.2004","article-title":"Serotype-specific entry of dengue virus into liver cells: Identification of the 37-kilodalton\/67-kilodalton high-affinity laminin receptor as a dengue virus serotype 1 receptor","volume":"78","author":"Thepparit","year":"2004","journal-title":"J. Virol."},{"key":"ref_394","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1159\/000089377","article-title":"Growth and production of the dengue virus in C6\/36 cells and identification of a laminin-binding protein as a candidate serotype 3 and 4 receptor protein","volume":"49","author":"Sakoonwatanyoo","year":"2006","journal-title":"Intervirology"},{"key":"ref_395","doi-asserted-by":"crossref","first-page":"2650","DOI":"10.1128\/JVI.73.4.2650-2657.1999","article-title":"Bacterial lipopolysaccharide inhibits dengue virus infection of primary human monocytes\/macrophages by blockade of virus entry via a CD14-dependent mechanism","volume":"73","author":"Chen","year":"1999","journal-title":"J. Virol."},{"key":"ref_396","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1093\/jb\/mvj067","article-title":"Identification and characterization of carbohydrate molecules in mammalian cells recognized by dengue virus type 2","volume":"139","author":"Aoki","year":"2006","journal-title":"J. Biochem."},{"key":"ref_397","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1111\/j.1348-0421.2010.00293.x","article-title":"Dengue virus type 2 recognizes the carbohydrate moiety of neutral glycosphingolipids in mammalian and mosquito cells","volume":"55","author":"Wichit","year":"2011","journal-title":"Microbiol. Immunol."},{"key":"ref_398","doi-asserted-by":"crossref","first-page":"2610","DOI":"10.4049\/jimmunol.0802806","article-title":"NKp44 receptor mediates interaction of the envelope glycoproteins from the West Nile and dengue viruses with NK cells","volume":"183","author":"Hershkovitz","year":"2009","journal-title":"J. Immunol."},{"key":"ref_399","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.virol.2010.07.015","article-title":"Identification and characterization of prohibitin as a receptor protein mediating DENV-2 entry into insect cells","volume":"406","author":"Kuadkitkan","year":"2010","journal-title":"Virology"},{"key":"ref_400","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1093\/femsre\/fuu004","article-title":"Receptors and routes of dengue virus entry into the host cells","volume":"39","author":"Freire","year":"2015","journal-title":"FEMS Microbiol. Rev."},{"key":"ref_401","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1038\/nrm2216","article-title":"Pathways of clathrin-independent endocytosis","volume":"8","author":"Mayor","year":"2007","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"ref_402","doi-asserted-by":"crossref","first-page":"4881","DOI":"10.1128\/JVI.02210-06","article-title":"Rab5 is required for the cellular entry of dengue and West Nile viruses","volume":"81","author":"Krishnan","year":"2007","journal-title":"J. Virol."},{"key":"ref_403","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.virusres.2011.06.008","article-title":"Infectious dengue-1 virus entry into mosquito C6\/36 cells","volume":"160","author":"Acosta","year":"2011","journal-title":"Virus Res."},{"key":"ref_404","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1111\/j.1462-5822.2009.01345.x","article-title":"Alternative infectious entry pathways for dengue virus serotypes into mammalian cells","volume":"11","author":"Acosta","year":"2009","journal-title":"Cell. Microbiol."},{"key":"ref_405","doi-asserted-by":"crossref","unstructured":"Alhoot, M.A., Wang, S.M., and Sekaran, S.D. (2012). RNA interference mediated inhibition of dengue virus multiplication and entry in HepG2 cells. PLoS ONE, 7.","DOI":"10.1371\/journal.pone.0034060"},{"key":"ref_406","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1139\/W08-107","article-title":"Entry of dengue virus serotype 2 into ECV304 cells depends on clathrin-dependent endocytosis, but not on caveolae-dependent endocytosis","volume":"55","author":"Peng","year":"2009","journal-title":"Can. J. Microbiol."},{"key":"ref_407","doi-asserted-by":"crossref","unstructured":"Alhoot, M.A., Wang, S.M., and Sekaran, S.D. (2011). Inhibition of dengue virus entry and multiplication into monocytes using RNA interference. PLoS Negl. Trop. Dis., 5.","DOI":"10.1371\/journal.pntd.0001410"},{"key":"ref_408","doi-asserted-by":"crossref","unstructured":"Geoghegan, V., Stainton, K., Rainey, S.M., Ant, T.H., Dowle, A.A., Larson, T., Hester, S., Charles, P.D., Thomas, B., and Sinkins, S.P. (2017). Perturbed cholesterol and vesicular trafficking associated with dengue blocking in Wolbachia-infected Aedes aegypti cells. Nat. Commun., 8.","DOI":"10.1038\/s41467-017-00610-8"},{"key":"ref_409","doi-asserted-by":"crossref","unstructured":"Wang, J.L., Zhang, J.L., Chen, W., Xu, X.F., Gao, N., Fan, D.Y., and An, J. (2010). Roles of small GTPase Rac1 in the regulation of actin cytoskeleton during dengue virus infection. PLoS Negl. Trop. Dis., 4.","DOI":"10.1371\/journal.pntd.0000809"},{"key":"ref_410","doi-asserted-by":"crossref","unstructured":"Shrivastava, N., Sripada, S., Kaur, J., Shah, P.S., and Cecilia, D. (2011). Insights into the internalization and retrograde trafficking of dengue 2 virus in BHK-21 cells. PLoS ONE, 6.","DOI":"10.1371\/journal.pone.0025229"},{"key":"ref_411","doi-asserted-by":"crossref","unstructured":"Fernandez-Garcia, M.D., Meertens, L., Chazal, M., Hafirassou, M.L., Dejarnac, O., Zamborlini, A., Despres, P., Sauvonnet, N., Arenzana-Seisdedos, F., and Jouvenet, N. (2016). Vaccine and wild-type strains of yellow fever virus engage distinct entry mechanisms and differentially stimulate antiviral immune responses. mBio, 7.","DOI":"10.1128\/mBio.01956-15"},{"key":"ref_412","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1111\/tra.12335","article-title":"Forty years of clathrin-coated vesicles","volume":"16","author":"Robinson","year":"2015","journal-title":"Traffic"},{"key":"ref_413","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1146\/annurev-biochem-060208-104626","article-title":"Virus entry by endocytosis","volume":"79","author":"Mercer","year":"2010","journal-title":"Annu. Rev. Biochem."},{"key":"ref_414","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1038\/nrm3151","article-title":"Molecular mechanism and physiological functions of clathrin-mediated endocytosis","volume":"12","author":"McMahon","year":"2011","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"ref_415","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1038\/nature07207","article-title":"RNA interference screen for human genes associated with West Nile virus infection","volume":"455","author":"Krishnan","year":"2008","journal-title":"Nature"},{"key":"ref_416","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1038\/nature07967","article-title":"Discovery of insect and human dengue virus host factors","volume":"458","author":"Sessions","year":"2009","journal-title":"Nature"},{"key":"ref_417","doi-asserted-by":"crossref","unstructured":"Le Sommer, C., Barrows, N.J., Bradrick, S.S., Pearson, J.L., and Garcia-Blanco, M.A. (2012). G protein-coupled receptor kinase 2 promotes flaviviridae entry and replication. PLoS Negl. Trop. Dis., 6.","DOI":"10.1371\/journal.pntd.0001820"},{"key":"ref_418","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1172\/JCI89857","article-title":"Anticancer kinase inhibitors impair intracellular viral trafficking and exert broad-spectrum antiviral effects","volume":"127","author":"Bekerman","year":"2017","journal-title":"J. Clin. Investig."},{"key":"ref_419","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1038\/nature09907","article-title":"A diverse range of gene products are effectors of the type I interferon antiviral response","volume":"472","author":"Schoggins","year":"2011","journal-title":"Nature"},{"key":"ref_420","doi-asserted-by":"crossref","first-page":"4246","DOI":"10.1073\/pnas.1720032115","article-title":"Flavivirus internalization is regulated by a size-dependent endocytic pathway","volume":"115","author":"Hackett","year":"2018","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_421","doi-asserted-by":"crossref","first-page":"7797","DOI":"10.1073\/pnas.1424098112","article-title":"RNASEK is required for internalization of diverse acid-dependent viruses","volume":"112","author":"Hackett","year":"2015","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_422","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1016\/j.celrep.2015.06.076","article-title":"RNASEK is a V-ATPase-associated factor required for endocytosis and the replication of rhinovirus, influenza A virus, and dengue virus","volume":"12","author":"Perreira","year":"2015","journal-title":"Cell Rep."},{"key":"ref_423","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1038\/nsmb.1456","article-title":"Viral membrane fusion","volume":"15","author":"Harrison","year":"2008","journal-title":"Nat. Struct. Mol. Biol."},{"key":"ref_424","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1038\/s41594-017-0010-8","article-title":"Structural biology of Zika virus and other flaviviruses","volume":"25","author":"Hasan","year":"2018","journal-title":"Nat. Struct. Mol. Biol."},{"key":"ref_425","doi-asserted-by":"crossref","first-page":"160","DOI":"10.3390\/v3020160","article-title":"Flavivirus cell entry and membrane fusion","volume":"3","author":"Smit","year":"2011","journal-title":"Viruses"},{"key":"ref_426","doi-asserted-by":"crossref","unstructured":"Liu, X., Zhao, X., Na, R., Li, L., Warkentin, E., Witt, J., Lu, X., Yu, Y., Wei, Y., and Peng, G. (2018). The structure differences of Japanese encephalitis virus SA14 and SA14-14-2 E proteins elucidate the virulence attenuation mechanism. Protein Cell.","DOI":"10.1007\/s13238-018-0551-6"},{"key":"ref_427","doi-asserted-by":"crossref","first-page":"11000","DOI":"10.1128\/JVI.01735-06","article-title":"Crystal structure of West Nile virus envelope glycoprotein reveals viral surface epitopes","volume":"80","author":"Kanai","year":"2006","journal-title":"J. Virol."},{"key":"ref_428","doi-asserted-by":"crossref","first-page":"11467","DOI":"10.1128\/JVI.01125-06","article-title":"Crystal structure of the West Nile virus envelope glycoprotein","volume":"80","author":"Nybakken","year":"2006","journal-title":"J. Virol."},{"key":"ref_429","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1128\/JVI.01950-12","article-title":"Structure of the St. Louis encephalitis virus postfusion envelope trimer","volume":"87","author":"Luca","year":"2013","journal-title":"J. Virol."},{"key":"ref_430","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1016\/j.chom.2016.04.013","article-title":"Structures of the Zika virus envelope protein and its complex with a flavivirus broadly protective antibody","volume":"19","author":"Dai","year":"2016","journal-title":"Cell Host Microbe"},{"key":"ref_431","doi-asserted-by":"crossref","first-page":"6986","DOI":"10.1073\/pnas.0832193100","article-title":"A ligand-binding pocket in the dengue virus envelope glycoprotein","volume":"100","author":"Modis","year":"2003","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_432","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1128\/JVI.79.2.1223-1231.2005","article-title":"Variable surface epitopes in the crystal structure of dengue virus type 3 envelope glycoprotein","volume":"79","author":"Modis","year":"2005","journal-title":"J. Virol."},{"key":"ref_433","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1038\/emboj.2011.439","article-title":"Structural insights into the neutralization mechanism of a higher primate antibody against dengue virus","volume":"31","author":"Cockburn","year":"2012","journal-title":"EMBO J."},{"key":"ref_434","doi-asserted-by":"crossref","first-page":"3178","DOI":"10.1128\/JVI.78.6.3178-3183.2004","article-title":"Characterization of a membrane-associated trimeric low-pH-induced form of the class II viral fusion protein E from tick-borne encephalitis virus and its crystallization","volume":"78","author":"Stiasny","year":"2004","journal-title":"J. Virol."},{"key":"ref_435","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.micinf.2010.09.005","article-title":"Molecular mechanisms involved in the early steps of flavivirus cell entry","volume":"13","author":"Kaufmann","year":"2011","journal-title":"Microbes Infect."},{"key":"ref_436","doi-asserted-by":"crossref","unstructured":"Kaufmann, B., Chipman, P.R., Holdaway, H.A., Johnson, S., Fremont, D.H., Kuhn, R.J., Diamond, M.S., and Rossmann, M.G. (2009). Capturing a flavivirus pre-fusion intermediate. PLoS Pathog., 5.","DOI":"10.1371\/journal.ppat.1000672"},{"key":"ref_437","doi-asserted-by":"crossref","first-page":"5159","DOI":"10.1128\/JVI.02099-10","article-title":"The helical domains of the stem region of dengue virus envelope protein are involved in both virus assembly and entry","volume":"85","author":"Lin","year":"2011","journal-title":"J. Virol."},{"key":"ref_438","doi-asserted-by":"crossref","first-page":"8495","DOI":"10.1128\/JVI.05129-11","article-title":"Mutational analysis of the zippering reaction during flavivirus membrane fusion","volume":"85","author":"Pangerl","year":"2011","journal-title":"J. Virol."},{"key":"ref_439","doi-asserted-by":"crossref","unstructured":"Schmidt, A.G., Yang, P.L., and Harrison, S.C. (2010). Peptide inhibitors of dengue virus entry target a late-stage fusion intermediate. PLoS Pathog., 6.","DOI":"10.1371\/journal.ppat.1000851"},{"key":"ref_440","doi-asserted-by":"crossref","first-page":"12549","DOI":"10.1128\/JVI.01440-10","article-title":"Peptide inhibitors of flavivirus entry derived from the E protein stem","volume":"84","author":"Schmidt","year":"2010","journal-title":"J. Virol."},{"key":"ref_441","doi-asserted-by":"crossref","first-page":"9933","DOI":"10.1128\/JVI.01283-13","article-title":"The membrane-proximal \u201cstem\u201d region increases the stability of the flavivirus E protein postfusion trimer and modulates its structure","volume":"87","author":"Stiasny","year":"2013","journal-title":"J. Virol."},{"key":"ref_442","doi-asserted-by":"crossref","first-page":"206","DOI":"10.15252\/embr.201745302","article-title":"The bright and the dark side of human antibody responses to flaviviruses: Lessons for vaccine design","volume":"19","author":"Rey","year":"2018","journal-title":"EMBO Rep."},{"key":"ref_443","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.virol.2016.08.013","article-title":"The ubiquitin-proteasome system is essential for the productive entry of Japanese encephalitis virus","volume":"498","author":"Wang","year":"2016","journal-title":"Virology"},{"key":"ref_444","doi-asserted-by":"crossref","unstructured":"Nour, A.M., Li, Y., Wolenski, J., and Modis, Y. (2013). Viral membrane fusion and nucleocapsid delivery into the cytoplasm are distinct events in some flaviviruses. PLoS Pathog., 9.","DOI":"10.1371\/journal.ppat.1003585"},{"key":"ref_445","doi-asserted-by":"crossref","unstructured":"Byk, L.A., Iglesias, N.G., De Maio, F.A., Gebhard, L.G., Rossi, M., and Gamarnik, A.V. (2016). Dengue virus genome uncoating requires ubiquitination. mBio, 7.","DOI":"10.1128\/mBio.00804-16"},{"key":"ref_446","doi-asserted-by":"crossref","first-page":"2980","DOI":"10.1128\/JVI.02483-10","article-title":"Appraising the roles of CBLL1 and the ubiquitin\/proteasome system for flavivirus entry and replication","volume":"85","author":"Meertens","year":"2011","journal-title":"J. Virol."},{"key":"ref_447","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/0166-0934(90)90021-7","article-title":"Entry and replication of Japanese encephalitis virus in cultured neurogenic cells","volume":"30","author":"Hase","year":"1990","journal-title":"J. Virol. Methods"}],"container-title":["Pathogens"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-0817\/7\/3\/68\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T15:18:22Z","timestamp":1760195902000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-0817\/7\/3\/68"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,13]]},"references-count":447,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2018,9]]}},"alternative-id":["pathogens7030068"],"URL":"https:\/\/doi.org\/10.3390\/pathogens7030068","relation":{},"ISSN":["2076-0817"],"issn-type":[{"value":"2076-0817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8,13]]}}}