{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T05:13:32Z","timestamp":1790745212589,"version":"4.1.0"},"reference-count":37,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2020,2,19]],"date-time":"2020-02-19T00:00:00Z","timestamp":1582070400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathogens"],"abstract":"<jats:p>Although Corynebacterium striatum is part of the human flora, it has recently drawn attention both for its multidrug resistance and its role as an invasive infection\/outbreak agent. This cross-sectional study aimed to determine the antimicrobial resistance and clonal relationships among C. striatum strains. In total, 81 C. striatum strains were identified using Phoenix-100TM (BD, Sparks, MD, USA). The antimicrobial resistance of the strains was determined using the Kirby\u2013Bauer disk diffusion method. Clonal relatedness among the strains was performed via arbitrarily primed polymerase chain reaction (AP-PCR). All 81 C. striatum strains were resistant to penicillin, cefotaxime, ciprofloxacin, and tetracycline, but susceptible to vancomycin and linezolid. The resistance rates to gentamicin, erythromycin, and clindamycin were 34.6%, 79%, and 87.7% respectively. AP-PCR results showed no predominant clone among the C. striatum strains. Corynebacterium striatum is reportedly the cause of an increasing number of invasive infections\/outbreaks. Moreover, treatment options are limited. The study showed that vancomycin, linezolid, and gentamicin can be selected for the empirical treatment of C. striatum infections. Although no single-clone outbreak was observed in our hospital, small clonal circulations were observed within some units, indicating cross-contamination. Therefore, a comprehensive infection control program is warranted in future.<\/jats:p>","DOI":"10.3390\/pathogens9020136","type":"journal-article","created":{"date-parts":[[2020,2,20]],"date-time":"2020-02-20T03:20:03Z","timestamp":1582168803000},"page":"136","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["Antimicrobial Resistance and Molecular Epidemiology of Corynebacterium striatum Isolated in a Tertiary Hospital in Turkey"],"prefix":"10.3390","volume":"9","author":[{"given":"Nergis","family":"Asgin","sequence":"first","affiliation":[{"name":"Department of Medical Microbiology, Faculty of Medicine, Karabuk University, 78100 Karabuk, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baris","family":"Otlu","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, Faculty of Medicine, Inonu University, 44280 Malatya, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,2,19]]},"reference":[{"key":"ref_1","first-page":"2373","article-title":"Other Coryneform Bacteria and Rhodococci","volume":"Volume 2","author":"Bennet","year":"2015","journal-title":"Mandell, Douglas, and Bennett\u2019s Principles and Practice of Infectious Diseases"},{"key":"ref_2","first-page":"474","article-title":"Coryneform Gram-Positive Rods","volume":"Volume 1","author":"Jorgensen","year":"2015","journal-title":"Manual of Clinical Microbiology"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.diagmicrobio.2012.07.001","article-title":"Microbiological investigation and clinical significance of Corynebacterium spp. in respiratory specimens","volume":"74","author":"Nhan","year":"2012","journal-title":"Diagn. 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