{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T01:34:41Z","timestamp":1792805681331,"version":"4.5.0"},"reference-count":41,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2020,5,4]],"date-time":"2020-05-04T00:00:00Z","timestamp":1588550400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"University Development Cooperation Program of 2017, of the Miguel Hern\u00e1ndez University of Elche, Spain.","award":["2017\/2"],"award-info":[{"award-number":["2017\/2"]}],"id":[{"id":"https:\/\/ror.org\/01azzms13","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathogens"],"abstract":"<jats:p>Strongyloidiasis is a soil-transmitted helminthiasis with a high global prevalence. Objectives: We aimed to evaluate the prevalence of Strongyloides stercoralis infection and assess strongyloidiasis serology as a screening technique in the Peruvian Amazon. Material and Methods: We performed a cross-sectional study of strongyloidiasis in 300 pregnant women in Iquitos (Peru) from 1 May 2019 to 15 June 2019. Women were tested using serology (Strongyloides IgG IVD-ELISA kit) as an index test and the modified Baermann technique and\/or charcoal fecal culture as the parasitological reference standard. Results: The reference tests showed S. stercoralis in the stool of 30 women (prevalence: 10%; 95% confidence interval [CI] 7.1% to 13.9%), while 101 women tested positive on the blood test (prevalence: 33.7%; 95% CI 28.6% to 39.4%). Fourteen of the 15 women (93.3%) with positive results according to the modified Baermann technique, and 14 of the 23 women (56.5%) with positive charcoal cultures also had positive serological results. Serology showed a sensitivity of 63.3% and a negative predictive value of 94.4%. Conclusion: In Iquitos, pregnant women have a high prevalence of S stercoralis. S. stercoralis ELISA could be an excellent tool for population-based screening, as it has a high negative predictive value that can help to rule out the presence of active infection.<\/jats:p>","DOI":"10.3390\/pathogens9050348","type":"journal-article","created":{"date-parts":[[2020,5,4]],"date-time":"2020-05-04T14:00:43Z","timestamp":1588600843000},"page":"348","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["A Cross-Sectional Study of Seroprevalence of Strongyloidiasis in Pregnant Women (Peruvian Amazon Basin)"],"prefix":"10.3390","volume":"9","author":[{"given":"Sonia","family":"Ortiz-Mart\u00ednez","sequence":"first","affiliation":[{"name":"Consultorio El Ballestero, Servicio de Salud Castellano Manchego, 2614 Albacete, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6501-9867","authenticated-orcid":false,"given":"Jos\u00e9-Manuel","family":"Ramos-Rinc\u00f3n","sequence":"additional","affiliation":[{"name":"Departamento de Medicina Cl\u00ednica, Universidad Miguel Hern\u00e1ndez de Elche, 03550 Alicante, Spain"},{"name":"Servicio de Medicina Interna, Hospital General Universitario de Alicante, 03010 Alicante, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda-Esteyner","family":"V\u00e1squez-Chasnamote","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n de Recursos Naturales, Universidad Nacional de la Amazonia Peruana, 16001 Iquitos, Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jhonatan","family":"Alarc\u00f3n-Balde\u00f3n","sequence":"additional","affiliation":[{"name":"Laboratorio Cl\u00ednico. Asociaci\u00f3n Civil Selva Amaz\u00f3nica, 16001 Iquitos, Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge","family":"Parraguez-de-la-Cruz","sequence":"additional","affiliation":[{"name":"Laboratorio Cl\u00ednico. Asociaci\u00f3n Civil Selva Amaz\u00f3nica, 16001 Iquitos, Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga-Nohelia","family":"Gamboa-Paredes","sequence":"additional","affiliation":[{"name":"Asistente de Investigaci\u00f3n, Asociaci\u00f3n Civil Selva Amaz\u00f3nica, 16001 Iquitos, Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Schillyk-Guerra","sequence":"additional","affiliation":[{"name":"Laboratorio Cl\u00ednico. Asociaci\u00f3n Civil Selva Amaz\u00f3nica, 16001 Iquitos, Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis-Alfredo","family":"Espinoza-Venegas","sequence":"additional","affiliation":[{"name":"Servicio de Enfermedades Infecciosas y Medicina Tropical, Hospital Regional de Loreto, 16001 Iquitos, Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viviana-Vanessa","family":"Pinedo-Cancino","sequence":"additional","affiliation":[{"name":"Laboratorio de Biolog\u00eda Molecular e Inmunolog\u00eda, Unidad Especializada del LIPNAA-CIRNA, Universidad Nacional de la Amazonia Peruana, 16001 Iquitos, Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9816-3208","authenticated-orcid":false,"given":"Ram\u00f3n","family":"Perez-Tanoira","sequence":"additional","affiliation":[{"name":"Servicio de Microbiologia, Hospital Universitario Pr\u00edncipe de Asturias, 28802 Alcal\u00e1 de Henares, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel","family":"G\u00f3rgolas-Hern\u00e1ndez-Mora","sequence":"additional","affiliation":[{"name":"Divisi\u00f3n de Enfermedades Infecciosas, Hospital Universitario Fundaci\u00f3n Jim\u00e9nez D\u00edaz, 28040 Madrid, Spain"},{"name":"Departamento de Medicina, Universidad Aut\u00f3noma de Madrid, 28029 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Casap\u00eda-Morales","sequence":"additional","affiliation":[{"name":"Servicio de Enfermedades Infecciosas y Medicina Tropical, Hospital Regional de Loreto, 16001 Iquitos, Peru"},{"name":"Departamento M\u00e9dico, Asociaci\u00f3n C\u00edvica Selva Amaz\u00f3nica, 16001 Iquitos, Peru"},{"name":"Facultad de Medicina, Universidad Nacional de la Amazonia Peruana, 496 Iquitos, Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Spanish-Peruvian Chagas, HTLV and Strongyloides Network","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,5,4]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.idc.2018.10.006","article-title":"Strongyloidiasis: A Neglected Tropical Disease","volume":"33","author":"Krolewiecki","year":"2019","journal-title":"Infect. 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