{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T15:18:05Z","timestamp":1786375085123,"version":"build-2736575974"},"reference-count":48,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2020,6,24]],"date-time":"2020-06-24T00:00:00Z","timestamp":1592956800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Institute of Health and Biometric Research of Alicante (ISABIAL)\/FISABIO Foundation","award":["UGP-16-158"],"award-info":[{"award-number":["UGP-16-158"]}]},{"name":"Collaboration agreement regulated under the Law of Patronage between ISABIAL\/FISABIO and the Foundation Mundo Sano, Spain.","award":["."],"award-info":[{"award-number":["."]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathogens"],"abstract":"<jats:p>Strongyloides stercoralis infection is frequently underdiagnosed since many infections remain asymptomatic. Aim: To estimate the prevalence and characteristics of asymptomatic S. stercoralis infection in Latin American migrants attending a community-based screening program for Chagas disease in Spain. Methodology: Three community-based Chagas disease screening campaigns were performed in Alicante (Spain) in 2016, 2017, and 2018. Serological testing for S. stercoralis infection was performed using a non-automatized IVD-ELISA detecting IgG (DRG Instruments GmbH, Marburg, Germany). Results: Of the 616 migrants from Central and South America who were screened, 601 were included in the study: 100 children and adolescents (&lt;18 years of age) and 501 adults. Among the younger group, 6 participants tested positive (prevalence 6%, 95% confidence interval [CI] 2.5% to 13.1%), while 60 adults did so (prevalence 12%, 95% CI 9.3% to 15.3%). S. stercoralis infection was more common in men than in women (odds ratio adjusted [ORa] 2.28, 95% CI 1.289 to 4.03) and in those from Bolivia (ORa 2.03, 95% CI 1.15 to 3.59). Prevalence increased with age (ORa 1.02, 95% CI 0.99 to 1.05). In contrast, a university education had a protective effect (ORa 0.29, 95% CI 0.31 to 0.88). Forty-one (41\/66; 62.1%) of the total cases of S. stercoralis infection were treated at the health care center. Positive stool samples were observed in 19.5% of the followed-up positive cases. Conclusion: Incorporating serological screening for S. stercoralis into community-based screening for Chagas disease is a useful intervention to detect asymptomatic S. stercoralis infection in Central and South American migrants and an opportunity to tackle neglected tropical diseases in a transversal way. The remaining challenge is to achieve patients\u2019 adherence to the medical follow-up.<\/jats:p>","DOI":"10.3390\/pathogens9060511","type":"journal-article","created":{"date-parts":[[2020,6,24]],"date-time":"2020-06-24T08:54:50Z","timestamp":1592988890000},"page":"511","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Asymptomatic Strongyloidiasis among Latin American Migrants in Spain: A Community-Based Approach"],"prefix":"10.3390","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3976-6700","authenticated-orcid":false,"given":"Violeta","family":"Ramos-Sesma","sequence":"first","affiliation":[{"name":"Internal Medicine Service, HLA Inmaculada Hospital, 18004 Granada, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7727-1587","authenticated-orcid":false,"given":"Miriam","family":"Navarro","sequence":"additional","affiliation":[{"name":"Public Health, Science History and Gynecology Department, Universidad Miguel Hern\u00e1ndez, 03550 Sant Joan d\u2019Alacant, Alicante, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9125-7706","authenticated-orcid":false,"given":"Jara","family":"Llenas-Garc\u00eda","sequence":"additional","affiliation":[{"name":"Internal Medicine Service, Vega Baja Hospital-FISABIO, Orihuela, 03314 Alicante, Spain"},{"name":"Clinica Medicine Department, University Miguel Hern\u00e1ndez de Elche, 03550 Sant Joan d\u2019Alacant, Alicante, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Concepci\u00f3n","family":"Gil-Anguita","sequence":"additional","affiliation":[{"name":"Internal Medicine Service, Marina 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Service, Marina Baixa Hospital, La Vila Joiosa, 03570 Alicante, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1979-0949","authenticated-orcid":false,"given":"Mar\u00eda-Paz","family":"Ventero-Mart\u00edn","sequence":"additional","affiliation":[{"name":"Microbiology Service, General University Hospital of Alicante -ISABIAL, 03010 Alicante, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana-Mar\u00eda","family":"Garijo-Sainz","sequence":"additional","affiliation":[{"name":"Internal Medicine Service, Marina Baixa Hospital, La Vila Joiosa, 03570 Alicante, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda","family":"Garc\u00eda-L\u00f3pez","sequence":"additional","affiliation":[{"name":"Internal Medicine Service, Vega Baja Hospital-FISABIO, Orihuela, 03314 Alicante, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4113-6986","authenticated-orcid":false,"given":"Ana-Isabel","family":"Pujades-T\u00e1rraga","sequence":"additional","affiliation":[{"name":"Internal Medicine Service, Marina Baixa Hospital, La Vila Joiosa, 03570 Alicante, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Bernal-Alcaraz","sequence":"additional","affiliation":[{"name":"Internal Medicine Service, Vega Baja Hospital-FISABIO, Orihuela, 03314 Alicante, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Santonja","sequence":"additional","affiliation":[{"name":"Internal Medicine Service, Marina Baixa Hospital, La Vila Joiosa, 03570 Alicante, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro","family":"Guevara-Hern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Internal Medicine Service, Vega Baja Hospital-FISABIO, Orihuela, 03314 Alicante, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2597-3100","authenticated-orcid":false,"given":"Mar\u00eda","family":"Flores-Ch\u00e1vez","sequence":"additional","affiliation":[{"name":"Foundation Mundo Sano, 28046 Madrid, Spain"},{"name":"Parasitology Service, National Center of Microbiology, 28222 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8950-5766","authenticated-orcid":false,"given":"Jos\u00e9-Mar\u00eda","family":"Saugar","sequence":"additional","affiliation":[{"name":"Parasitology Service, National Center of Microbiology, 28222 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6501-9867","authenticated-orcid":false,"given":"Jos\u00e9-Manuel","family":"Ramos-Rinc\u00f3n","sequence":"additional","affiliation":[{"name":"Clinica Medicine Department, University 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