{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:45:16Z","timestamp":1760060716586,"version":"build-2065373602"},"reference-count":15,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T00:00:00Z","timestamp":1757894400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Reports"],"abstract":"<jats:p>Bacterial meningitis is one of the most serious infections. Salmonella meningitis is associated with a high prevalence of long-term adverse outcomes, often linked to acute complications and a broad range of potential neurological sequelae following the infection. Acute complications such as brain abscesses and chronic complications such as hearing loss and developmental delay. In this report, we present a case of a 2-month-old male patient with seizures, hypoactivity and respiratory symptoms, who was found to have Salmonella bacteremia complicated by Salmonella and Human Herpes Virus-6 (HHV-6) meningitis, as well as rhinovirus bronchiolitis, along with follow-up findings. The patient\u2019s data, including demographics, presenting symptoms, physical examination findings, and whole exome sequence results, as well as investigations such as complete blood count (CBC), cerebrospinal fluid (CSF) analysis, liver enzyme levels, and imaging findings, were collected from the electronic medical record system using a case report form. In addition, immunological workups were performed, as serious Salmonella infections were more common in immunocompromised patients. In the literature, there was no clear correlation between Salmonella and HHV-6 meningitis, rhinovirus bronchiolitis, and the complications that developed in this infant. This case report provides valuable insights into the clinical spectrum and long-term outcomes of patients with Salmonella meningitis.<\/jats:p>","DOI":"10.3390\/pediatric17050094","type":"journal-article","created":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T08:56:46Z","timestamp":1758013006000},"page":"94","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Case Report of Salmonella and HHV-6 Meningitis in an Infant"],"prefix":"10.3390","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8387-4253","authenticated-orcid":false,"given":"Sara","family":"Abed","sequence":"first","affiliation":[{"name":"Department of Pediatrics, King Abdullah Specialized Children\u2019s Hospital, Ministry of National Guard Health Affairs (MNGHA), King Saud Bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, Jeddah 21423, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tahani","family":"Asiri","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, King Abdullah Specialized Children\u2019s Hospital, Ministry of National Guard Health Affairs (MNGHA), Jeddah 21423, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Razan","family":"Alzahrani","sequence":"additional","affiliation":[{"name":"East Jeddah Hospital, Jeddah 22253, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wujud","family":"Hunjur","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, King Abdullah Specialized Children\u2019s Hospital, Ministry of National Guard Health Affairs (MNGHA), Jeddah 21423, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,9,15]]},"reference":[{"key":"ref_1","unstructured":"Hersi, K., Gonzalez, F.J., and Kondamudi, N.P. (2024, March 01). Meningitis. [Updated 2023 Aug 12], StatPearls [Internet], Available online: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK459360\/."},{"key":"ref_2","first-page":"e44147","article-title":"Salmonella Meningitis in a Young Infant: A Case Report","volume":"15","author":"Elouali","year":"2023","journal-title":"Cureus"},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Wu, H.M., Huang, W.Y., Lee, M.L., Yang, A.D., Chaou, K.P., and Hsieh, L.Y. (2011). Clinical features, acute complications, and outcome of Salmonella meningitis in children under one year of age in Taiwan. BMC Infect. Dis., 11, Available online: https:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/1471-2334-11-30.","DOI":"10.1186\/1471-2334-11-30"},{"key":"ref_4","unstructured":"Burrows, W. (1959). Textbook of Microbiology, WB Saunders. 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Pediatr."}],"container-title":["Pediatric Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2036-7503\/17\/5\/94\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T18:45:49Z","timestamp":1760035549000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2036-7503\/17\/5\/94"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,15]]},"references-count":15,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2025,10]]}},"alternative-id":["pediatric17050094"],"URL":"https:\/\/doi.org\/10.3390\/pediatric17050094","relation":{},"ISSN":["2036-7503"],"issn-type":[{"type":"electronic","value":"2036-7503"}],"subject":[],"published":{"date-parts":[[2025,9,15]]}}}