{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T12:46:21Z","timestamp":1785415581339,"version":"3.56.0"},"reference-count":21,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"University of Tennessee"},{"id":[{"id":"https:\/\/ror.org\/020f3ap87","id-type":"ROR","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Reports"],"abstract":"<jats:p>Background: Critically ill children requiring extracorporeal membrane oxygenation (ECMO) support are at high risk of immobility, deconditioning, and muscle loss. There is a lack of screening and diagnostic tools to quantify muscle loss in this population. Objective: This study aims to evaluate the use of bedside ultrasound as a practical and effective method for detecting muscle loss in this high-risk group. Materials and Methods: This is a secondary analysis of a prospective observational clinical study conducted between January 2024 and January 2025 that used ultrasound to describe muscle loss in critically ill children aged 2 to 18 years. Results: The primary study enrolled 35 patients, five of whom required ECMO support. All patients who required ECMO showed significant muscle loss (&gt;10%) in the quadriceps femoris, as measured by muscle thickness and cross-sectional area, compared with baseline measurements obtained before ECMO cannulation. Conclusions: Point-of-care muscle ultrasound could be a reliable, cost-effective tool for assessing muscle loss in pediatric patients on ECMO.<\/jats:p>","DOI":"10.3390\/pediatric18030063","type":"journal-article","created":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T10:15:27Z","timestamp":1777630527000},"page":"63","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Point-of-Care Ultrasound Detects Rapid Muscle Loss in Pediatric ECMO Patients\u2014A Secondary Analysis Paper"],"prefix":"10.3390","volume":"18","author":[{"given":"Mohammad","family":"Sabobeh","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Critical Care Medicine, The University of Tennessee Health and Science Center, Memphis, TN 38163, USA"},{"name":"Department of Pediatric Medicine, St. Jude Children\u2019s Research Hospital, Memphis, TN 38105, USA"},{"name":"Department of Pediatrics, Critical Care Medicine, The University of South Alabama Women and Children\u2019s Hospital, Mobile, AL 36604, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3112-8739","authenticated-orcid":false,"given":"Elizabeth","family":"Seewer","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Critical Care Medicine, The University of Tennessee Health and Science Center, Memphis, TN 38163, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William Hunt","family":"Stafford","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Critical Care Medicine, The University of Tennessee Health and Science Center, Memphis, TN 38163, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Chiriboga","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Critical Care Medicine, The University of Tennessee Health and Science Center, Memphis, TN 38163, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9031-645X","authenticated-orcid":false,"given":"Thomas","family":"Spentzas","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Critical Care Medicine, The University of Tennessee Health and Science Center, Memphis, TN 38163, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shyam","family":"Popat","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Critical Care Medicine, The University of Tennessee Health and Science Center, Memphis, TN 38163, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alyssa","family":"Clark","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Critical Care Medicine, The University of Tennessee Health and Science Center, Memphis, TN 38163, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David B.","family":"Kantor","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Critical Care, and Pain Medicine, Boston Children\u2019s Hospital, Boston, MA 02115, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0869-2841","authenticated-orcid":false,"given":"Hitesh S.","family":"Sandhu","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Critical Care Medicine, The University of Tennessee Health and Science Center, Memphis, TN 38163, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saad","family":"Ghafoor","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Critical Care Medicine, The University of Tennessee Health and Science Center, Memphis, TN 38163, USA"},{"name":"Department of Pediatric Medicine, St. Jude Children\u2019s Research Hospital, Memphis, TN 38105, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,5,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2763","DOI":"10.21037\/tp-20-298","article-title":"A narrative review of skeletal muscle atrophy in critically ill children: Pathogenesis and chronic sequelae","volume":"10","author":"Ong","year":"2021","journal-title":"Transl. 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