{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T10:03:24Z","timestamp":1789639404422,"version":"4.0.0"},"reference-count":40,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T00:00:00Z","timestamp":1789430400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr. Rep.","Pediatric Reports"],"abstract":"<jats:p>Background\/Objectives: Childhood cancer profoundly affects families, particularly parents, who assume demanding caregiving roles associated with significant emotional and social burden that remain underexplored qualitatively. To explore the experiences of parents of children with cancer during the disease process: diagnosis, treatment, follow-up, and their child\u2019s progress. Methods: An exploratory qualitative interview study was conducted using individual semi-structured interviews with six parents of children with cancer in Spain. Participants were intentionally recruited through a parent association. Interviews were conducted online, audio- and video-recorded with consent, transcribed verbatim, and analyzed using thematic analysis following Braun and Clarke. Sullivan\u2019s interpersonal theory was subsequently used as a conceptual framework to interpret the emerging themes, particularly in relation to interpersonal anxiety, security, emotional regulation, and significant relationships. Results: Six parents were included in the analysis, representing heterogeneous clinical trajectories, including active treatment, remission, and bereavement. Five axes, 12 categories, and 52 codes were identified. Parents described uncertainty and emotional disruption around diagnosis, the coexistence of perceived strength and distress during treatment, changes in family and interpersonal relationships, continuing concerns following remission, and profound grief and continuing bonds following the death of a child. These findings were interpreted through Sullivan\u2019s interpersonal framework. Conclusions: This exploratory study suggests that parents\u2019 experiences of childhood cancer are shaped by changes in interpersonal relationships, emotional regulation, perceived security, and support networks across different phases of the illness. The findings highlight potential areas for psychosocial support, although they should be interpreted cautiously given the small and heterogeneous sample.<\/jats:p>","DOI":"10.3390\/pediatric18050120","type":"journal-article","created":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T10:32:01Z","timestamp":1789468321000},"page":"120","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Experiences of Parents of Children with Cancer During Their Child\u2019s Illness: A Qualitative Interview Study in a Spanish Context"],"prefix":"10.3390","volume":"18","author":[{"given":"Fernando","family":"Santamar\u00eda-Fraile","sequence":"first","affiliation":[{"name":"Valladolid University Clinical Hospital, 47003 Valladolid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"conceptualization","vocabulary":"credit"},{"role":"methodology","vocabulary":"credit"},{"role":"formal-analysis","vocabulary":"credit"},{"role":"writing-original-draft","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2532-8307","authenticated-orcid":false,"given":"Rosa M.","family":"C\u00e1rdaba-Garc\u00eda","sequence":"additional","affiliation":[{"name":"Department of Nursing, University of Valladolid, 47005 Valladolid, Spain"},{"name":"Nursing Care Research Group, University of Valladolid, 47005 Valladolid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"conceptualization","vocabulary":"credit"},{"role":"methodology","vocabulary":"credit"},{"role":"writing-original-draft","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"},{"role":"software","vocabulary":"credit"},{"role":"formal-analysis","vocabulary":"credit"}]},{"given":"Inmaculada","family":"P\u00e9rez","sequence":"additional","affiliation":[{"name":"Department of Nursing, University of Valladolid, 47005 Valladolid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"formal-analysis","vocabulary":"credit"},{"role":"investigation","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4739-9760","authenticated-orcid":false,"given":"Ver\u00f3nica","family":"Velasco-Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Department of Nursing, University of Valladolid, 47005 Valladolid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baldomero","family":"de Maya-S\u00e1chez","sequence":"additional","affiliation":[{"name":"Department of Nursing, University of Valladolid, 47005 Valladolid, Spain"},{"name":"Nursing Care Research Group, University of Valladolid, 47005 Valladolid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"formal-analysis","vocabulary":"credit"},{"role":"data-curation","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9388-8074","authenticated-orcid":false,"given":"Carlos","family":"Durantez-Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Department of Nursing, University of Valladolid, 47005 Valladolid, Spain"},{"name":"Nursing Care Research Group, University of Valladolid, 47005 Valladolid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"formal-analysis","vocabulary":"credit"},{"role":"data-curation","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6031-6619","authenticated-orcid":false,"given":"Luc\u00eda","family":"P\u00e9rez-P\u00e9rez","sequence":"additional","affiliation":[{"name":"Department of Nursing, University of Valladolid, 47005 Valladolid, Spain"},{"name":"Nursing Care Research Group, University of Valladolid, 47005 Valladolid, Spain"},{"name":"Valladolid West Primary Care Management (SACYL), 47012 Valladolid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"formal-analysis","vocabulary":"credit"},{"role":"methodology","vocabulary":"credit"},{"role":"writing-original-draft","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"}]}],"member":"1968","published-online":{"date-parts":[[2026,9,15]]},"reference":[{"key":"ref_1","unstructured":"National Cancer Institute (2026, July 01). Childhood Cancers, Available online: https:\/\/www.cancer.gov\/types\/childhood-cancers."},{"key":"ref_2","unstructured":"(2026, July 01). Registro Espa\u00f1ol de Tumores Infantiles [Spanish Registry of Childhood Tumors]. Informes RETI-SEHOP. Available online: https:\/\/www.uv.es\/uvweb\/registro-espanyol-tumores-infantiles-RETI-SEHOP\/es\/cancer-infantil-cifras\/informes-reti-sehop-1285944920873.html."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"102022","DOI":"10.1016\/j.ejon.2021.102022","article-title":"Predictors of parenting stress in parents of children with cancer","volume":"54","author":"Boztepe","year":"2021","journal-title":"Eur. J. Oncol. Nurs."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"e244531","DOI":"10.1001\/jamanetworkopen.2024.4531","article-title":"Mental Health Care Utilization Among Parents of Children with Cancer","volume":"7","author":"Hu","year":"2024","journal-title":"JAMA Netw. Open"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"e2137250","DOI":"10.1001\/jamanetworkopen.2021.37250","article-title":"Association Between Children with Life-Threatening Conditions and Their Parents\u2019 and Siblings\u2019 Mental and Physical Health","volume":"4","author":"Feudtner","year":"2021","journal-title":"JAMA Netw. Open"},{"key":"ref_6","first-page":"18","article-title":"\u00bfEspecializaci\u00f3n o simetr\u00eda en la participaci\u00f3n laboral de las parejas? Un marco anal\u00edtico para estudiar las diferencias de g\u00e9nero en Espa\u00f1a","volume":"9","author":"Tejero","year":"2024","journal-title":"Quad. Pol\u00edtiques Fam."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1002\/pon.5689","article-title":"Social support and siblings of children with cancer: A scoping review","volume":"30","author":"Wawrzynski","year":"2021","journal-title":"Psychooncology"},{"key":"ref_8","unstructured":"Barton, F. (1996). Harry Stack Sullivan. Interpersonal Theory and Psychotherapy, Rouledge."},{"key":"ref_9","first-page":"114","article-title":"Prevalence of Anxiety, Depression, and Post-Traumatic Stress Disorder among Children and Adolescents with Cancer: A Systematic Review and Meta-Analysis","volume":"39","author":"Chan","year":"2022","journal-title":"J. Pediatr. Hematol. Oncol. Nurs."},{"key":"ref_10","first-page":"71","article-title":"Factors Associated with Post-Traumatic Growth in Korean Survivors of Childhood Cancer","volume":"49","author":"Kim","year":"2022","journal-title":"Oncol. Nurs. Forum"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1093\/intqhc\/mzm042","article-title":"Consolidated criteria for reporting qualitative research (COREQ): A 32-item checklist for interviews and focus groups","volume":"19","author":"Tong","year":"2007","journal-title":"Int. J. Qual. Health Care"},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Guba, E., and Lincoln, Y.S. (1985). Naturalistic Inquiry, Sage Publications.","DOI":"10.1016\/0147-1767(85)90062-8"},{"key":"ref_13","unstructured":"(2026, July 01). Ley Org\u00e1nica 3\/2018, de 5 de Diciembre, de Protecci\u00f3n de Datos Personales y Garant\u00eda de los Derechos Digitales. Available online: https:\/\/www.boe.es\/buscar\/act.php?id=BOE-A-2018-16673."},{"key":"ref_14","doi-asserted-by":"crossref","unstructured":"World Medical Association (2013). World Medical Association Declaration of Helsinki: Ethical principles for medical research involving human subjects. JAMA, 310, 2191\u20132194.","DOI":"10.1001\/jama.2013.281053"},{"key":"ref_15","unstructured":"(2026, July 01). Reglamento (UE) 2016\/679 del Parlamento Europeo y del Consejo de 27 de Abril de 2016 Relativo a la Protecci\u00f3n de Las Personas F\u00edsicas en lo Que Respecta al Tratamiento de Datos Personales y a la Libre Circulaci\u00f3n de Estos Datos y Por el Que se Deroga la Directiva 95\/46\/CE (Reglamento General de Protecci\u00f3n de Datos). Available online: https:\/\/eur-lex.europa.eu\/legal-content\/ES\/TXT\/?uri=celex:32016R0679."},{"key":"ref_16","first-page":"56","article-title":"Activism, Coping, and Hopefulness Among Parents of Children with Cancer","volume":"41","author":"Neenan","year":"2024","journal-title":"J. Pediatr. Hematol. Oncol. Nurs."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1093\/jpepsy\/jsac097","article-title":"Profiles of Resilience, Distress, and Posttraumatic Growth in Parents of Children with Cancer and the Relation to Subsequent Parenting and Family Functioning","volume":"48","author":"Cook","year":"2023","journal-title":"J. Pediatr. Psychol."},{"key":"ref_18","first-page":"1","article-title":"Experiencias y necesidades percibidas por los ni\u00f1os y adolescentes con c\u00e1ncer y por sus familias","volume":"16","year":"2005","journal-title":"NURE Investig."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"e29850","DOI":"10.1002\/pbc.29850","article-title":"Prospective registration of symptoms and times to diagnosis in children and adolescents with central nervous system tumors: A study of the Swedish Childhood Cancer Registry","volume":"69","author":"Rask","year":"2022","journal-title":"Pediatr. Blood Cancer"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1093\/jpepsy\/jsae077","article-title":"Posttraumatic stress symptoms in parents of children with newly diagnosed cancer: 1-year trajectories and relationship variables as predictors","volume":"49","author":"Vogt","year":"2024","journal-title":"J. Pediatr. Psychol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1080\/24694193.2023.2168790","article-title":"What Was on the Parents\u2019 Minds? Changes Over Time in Topics of Person-Centred Information for Mothers and Fathers of Children with Cancer","volume":"46","author":"Olsson","year":"2023","journal-title":"Compr. Child. Adolesc. Nurs."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"e31726","DOI":"10.1002\/pbc.31726","article-title":"Illness Uncertainty in Parents of Children with Cancer-An Exploratory Analysis to Inform Intervention Development","volume":"72","author":"Mazzola","year":"2025","journal-title":"Pediatr. Blood Cancer"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"e98","DOI":"10.1016\/j.pedn.2023.06.015","article-title":"Nursing practice to fulfill the information needs of parents of hospitalized children with cancer and related factors","volume":"72","author":"Hashimoto","year":"2023","journal-title":"J. Pediatr. Nurs."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1017\/S1478951520000449","article-title":"A review of psychosocial interventions targeting families of children with cancer","volume":"19","author":"Koumarianou","year":"2021","journal-title":"Palliat. Support. Care"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1093\/jpepsy\/jsae048","article-title":"In their own words: Advice from parents of children with cancer","volume":"49","author":"Davies","year":"2024","journal-title":"J. Pediatr. Psychol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1136\/archdischild-2022-324905","article-title":"Experiences and support needs of par-ents\/caregivers of children with cancer through the COVID-19 pandemic in the UK: A longitudinal study","volume":"108","author":"Gamble","year":"2023","journal-title":"Arch. Dis. Child."},{"key":"ref_27","unstructured":"Hern\u00e1ndez-Garc\u00eda, M., and Vallejo-Serna, E. (2026). Funcionalidad Familiar en Situaci\u00f3n de C\u00e1ncer Infantil Revisi\u00f3n Integrativa de Literatura Per\u00edodo 2020\u20132025. [Bachelor\u2019s Thesis, Fundaci\u00f3n Universitaria del Areandina]."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"e27677","DOI":"10.1002\/pbc.27677","article-title":"Prevalence of anxiety, depression, and posttraumatic stress disorder in parents of children with cancer: A Meta-analysis","volume":"66","author":"Zabih","year":"2019","journal-title":"Pediatr. Blood Cancer"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1080\/14737140.2023.2245148","article-title":"Pediatric cancer care management during the COVID-19 pandemic: A review of the literature and a single-centre real-life experience of an Italian pediatric oncology unit","volume":"23","author":"Nigro","year":"2023","journal-title":"Expert. Rev. Anticancer. Ther."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"E43","DOI":"10.1097\/NCC.0000000000000841","article-title":"A Systematic Mixed-Studies Review of Hope Experiences in Parents of Children with Cancer","volume":"45","author":"Eche","year":"2022","journal-title":"Cancer Nurs."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"e70018","DOI":"10.1002\/pon.70018","article-title":"How Do Parents with Advanced Cancer Communicate with Their Children? A Systematic Review and Meta-Synthesis of Qualitative Studies","volume":"33","author":"Xu","year":"2024","journal-title":"Psychooncology"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1093\/jpepsy\/jsab100","article-title":"Social Support in Parents of Children with Cancer: A Systematic Review","volume":"47","author":"Gise","year":"2022","journal-title":"J. Pediatr. Psychol."},{"key":"ref_33","first-page":"295","article-title":"Care Needs of Parents of Children with Cancer in a Low-Middle-Income Country","volume":"40","author":"Banayat","year":"2023","journal-title":"J. Pediatr. Hematol. Oncol. Nurs."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"E12","DOI":"10.1097\/NCC.0000000000000258","article-title":"A Systematic Review of the Experiences of Siblings of Children with Cancer","volume":"39","author":"Yang","year":"2016","journal-title":"Cancer Nurs."},{"key":"ref_35","first-page":"95","article-title":"Maternal perception of a child with cancer","volume":"25","year":"2022","journal-title":"J. Mother Child"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1097\/00002820-200403000-00002","article-title":"Gender differences in the use of coping strategies among Taiwanese parents whose children have cancer","volume":"27","author":"Yeh","year":"2004","journal-title":"Cancer Nurs."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1111\/hir.12491","article-title":"Parents of children with cancer require health literacy support to meet their information needs","volume":"41","author":"Tan","year":"2024","journal-title":"Health Inf. Libr. J."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"2711","DOI":"10.1590\/S1413-81232013000900026","article-title":"Impacto da morte do filho sobre a conjugalidade dos pais [The impact of a child\u2019s death on the marital relationship of the parents]","volume":"18","author":"Morelli","year":"2013","journal-title":"Cienc. Saude Coletiva"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1176\/appi.psychotherapy.1977.31.3.417","article-title":"Family sequelae after a child\u2019s death due to cancer","volume":"31","author":"Tietz","year":"1977","journal-title":"Am. J. Psychother."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"102078","DOI":"10.1016\/j.ejon.2021.102078","article-title":"Family resilience factors affecting family adaptation of children with cancer: A cross-sectional study","volume":"56","author":"Park","year":"2022","journal-title":"Eur. J. Oncol. Nurs. Off. J. Eur. Oncol. Nurs. 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