{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T11:04:50Z","timestamp":1791284690629,"version":"4.1.0"},"reference-count":78,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2023,9,30]],"date-time":"2023-09-30T00:00:00Z","timestamp":1696032000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"South African National Research Foundation (NRF)","award":["117898"],"award-info":[{"award-number":["117898"]}]},{"name":"South African National Research Foundation (NRF)","award":["117872"],"award-info":[{"award-number":["117872"]}]},{"name":"NRF Thuthuka","award":["117898"],"award-info":[{"award-number":["117898"]}]},{"name":"NRF Thuthuka","award":["117872"],"award-info":[{"award-number":["117872"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pharmaceuticals"],"abstract":"<jats:p>Plants of the Suregada Roxb. ex Rottler (formerly Gelonium Roxb. ex Willd) are utilized to treat various ailments, namely, hepatic, gum diseases, pyrexia, eczema, and venereal diseases. This review links the reported compounds to ethnomedicinal uses through pharmacological activities. The compounds possess anticancer, anti-allergic, antibacterial, anti-inflammatory, antioxidant, and anti-HIV properties. From the previous reports, 32 known species of the Suregada genus have been investigated morphologically, and nine were investigated for their phytochemistry and pharmacology. Phytochemistry, ethnomedicinal, and pharmacological uses of the other 23 Suregada species are not known and\/or not reported. In this review, abietane diterpenoids are the main compounds expressed by the Suregada, accounting for 71 of the 114 reported compounds. Ten triterpenoids and sterols, one aliphatic, two lignans, five flavonoids, and twenty-one nitrogen-containing compounds have been reported from the genus.<\/jats:p>","DOI":"10.3390\/ph16101390","type":"journal-article","created":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T16:57:06Z","timestamp":1696179426000},"page":"1390","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Ethnomedicinal Uses, Phytochemistry and Pharmacological Properties of Suregada Genus: A Review"],"prefix":"10.3390","volume":"16","author":[{"given":"Mandisa","family":"Mangisa","sequence":"first","affiliation":[{"name":"Department of Chemistry, Tshwane University of Technology, Private Bag X680, Pretoria 0001, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3771-128X","authenticated-orcid":false,"given":"Douglas","family":"Kemboi","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Tshwane University of Technology, Private Bag X680, Pretoria 0001, South Africa"},{"name":"Department of Chemistry, University of Kabianga, Kericho 2030, Kenya"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2123-7774","authenticated-orcid":false,"given":"Gerda","family":"Fouche","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Pretoria, Private Bag X20, Pretoria 0001, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rudzani","family":"Nthambeleni","sequence":"additional","affiliation":[{"name":"Biosciences, Council for Scientific and Industrial Research, Pretoria 0001, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8079-7774","authenticated-orcid":false,"given":"Moses Kiprotich","family":"Langat","sequence":"additional","affiliation":[{"name":"Science Department, Royal Botanic Gardens, Kew TW9 3DS, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5444-4457","authenticated-orcid":false,"given":"Clemence","family":"Tarirai","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, Tshwane University of Technology, Private Bag X680, Pretoria 0001, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Cheek","sequence":"additional","affiliation":[{"name":"Science Department, Royal Botanic Gardens, Kew TW9 3DS, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4195-5607","authenticated-orcid":false,"given":"Odwa","family":"Gonyela","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Tshwane University of Technology, Private Bag X680, Pretoria 0001, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vuyelwa Jacqueline","family":"Tembu","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Tshwane University of Technology, Private Bag X680, Pretoria 0001, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,9,30]]},"reference":[{"key":"ref_1","unstructured":"(2022, August 11). 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