{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T02:16:18Z","timestamp":1779934578887,"version":"3.53.1"},"reference-count":131,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2023,11,7]],"date-time":"2023-11-07T00:00:00Z","timestamp":1699315200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pharmaceuticals"],"abstract":"<jats:p>Turnera is a genus of plants whose biological activity has been widely studied. The importance of this genus, particularly Turnera diffusa, as a source of treatment for various conditions is evidenced by the large number of new studies that have evaluated its biological activity. Accordingly, the objective of this review was to compile the information published in the last ten years concerning the biological activities reported for Turnera spp. The present work includes 92 publications that evaluate 29 bioactivities and toxicological and genotoxic information on five species of this genus. Among the pharmacological effects reported, the antioxidant, hepatoprotective, neuroprotective, hypoglycemic, and aphrodisiac activities seem more promising. Phytochemicals and standardized plant extracts could offer alternative therapeutic remedies for various diseases. Although several flavonoids, cyanogenic glycosides, monoterpenoids, triterpenoids, and fatty acids have been isolated for Turnera plants, future research should focus on the identification of the main active principles responsible for these pharmacological activities, as well as to perform clinical trials to support the laboratory results.<\/jats:p>","DOI":"10.3390\/ph16111573","type":"journal-article","created":{"date-parts":[[2023,11,7]],"date-time":"2023-11-07T11:23:39Z","timestamp":1699356219000},"page":"1573","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Bioactivity of the Genus Turnera: A Review of the Last 10 Years"],"prefix":"10.3390","volume":"16","author":[{"given":"A\u00edda","family":"Parra-Naranjo","sequence":"first","affiliation":[{"name":"Facultad de Medicina, Departamento de Qu\u00edmica Anal\u00edtica, Universidad Aut\u00f3noma de Nuevo Le\u00f3n, Monterrey 64460, Nuevo Le\u00f3n, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cecilia","family":"Delgado-Montemayor","sequence":"additional","affiliation":[{"name":"Facultad de Medicina, Departamento de Qu\u00edmica Anal\u00edtica, Universidad Aut\u00f3noma de Nuevo Le\u00f3n, Monterrey 64460, Nuevo Le\u00f3n, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7448-5256","authenticated-orcid":false,"given":"Ricardo","family":"Salazar-Aranda","sequence":"additional","affiliation":[{"name":"Facultad de Medicina, Departamento de Qu\u00edmica Anal\u00edtica, Universidad Aut\u00f3noma de Nuevo Le\u00f3n, Monterrey 64460, Nuevo Le\u00f3n, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noem\u00ed","family":"Waksman-Minsky","sequence":"additional","affiliation":[{"name":"Facultad de Medicina, Departamento de Qu\u00edmica Anal\u00edtica, Universidad Aut\u00f3noma de Nuevo Le\u00f3n, Monterrey 64460, Nuevo Le\u00f3n, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,11,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1002\/tax.12210","article-title":"A lineage-based infrageneric classification of Turnera (Turneraceae)","volume":"69","author":"Rocha","year":"2020","journal-title":"Taxon"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.indcrop.2011.12.017","article-title":"Antioxidant and trace element content of damiana (Turnera diffusa Willd) under wild and cultivated conditions in semi-arid zones","volume":"37","author":"Puente","year":"2012","journal-title":"Ind. 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