{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T15:39:11Z","timestamp":1792597151951,"version":"4.5.0"},"reference-count":74,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2024,4,17]],"date-time":"2024-04-17T00:00:00Z","timestamp":1713312000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pharmaceuticals"],"abstract":"<jats:p>The present study focused on the mushroom Ganoderma, which has been used in Eastern countries for centuries as a food and medicinal source. Specifically, the fruiting bodies of Ganoderma applanatum from the Kerala Forest Research Institute in Thirussur, Kerala, India, were analyzed for their nutritional and medicinal properties. The methanolic extracts of G. applanatum were used to examine secondary metabolites and proximate profiles, revealing the presence of various phytochemicals such as terpenoids, phenolics, glycosides, alkaloids, flavonoids, and saponins. Further analysis revealed the presence of significant amounts of calcium, sodium, phosphorus, and manganese. The compounds were characterized using chromatographic analysis, FTIR, and GC-MS, which revealed potential therapeutic compounds with C-H and C-O bonds in the amide group, \u03b2-glycosides, and C-C\/C-O vibrations of phenolic substances. Mushroom extract at a concentration of 100 \u00b5g mL\u22121 exhibited potent antimicrobial activity against various pathogens. This study suggests that G. applanatum has a rich biochemical composition and pharmacological potential, making it a promising candidate for drug development and traditional medicine, and contributes valuable insights into its diverse therapeutic applications.<\/jats:p>","DOI":"10.3390\/ph17040509","type":"journal-article","created":{"date-parts":[[2024,4,17]],"date-time":"2024-04-17T08:22:44Z","timestamp":1713342164000},"page":"509","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Comprehensive Analysis of Bioactive Compounds in Wild Ganoderma applanatum Mushroom from Kerala, South India: Insights into Dietary Nutritional, Mineral, Antimicrobial, and Antioxidant Activities"],"prefix":"10.3390","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2037-0741","authenticated-orcid":false,"given":"Akbar","family":"Rijia","sequence":"first","affiliation":[{"name":"Department of Biology, The Gandhigram Rural Institute (Deemed to be University), Gandhigram, Dindigul 624302, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6508-5840","authenticated-orcid":false,"given":"Raman","family":"Krishnamoorthi","sequence":"additional","affiliation":[{"name":"Pharmaceutics Laboratory, Graduate Institute of Natural Products, Chang Gung University, Kweishan, Taoyuan 33302, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-8896-3348","authenticated-orcid":false,"given":"Madhusoodhanan","family":"Rasmi","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Bharathidasan University, Tiruchirappalli 620024, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4808-367X","authenticated-orcid":false,"given":"Pambayan Ulagan","family":"Mahalingam","sequence":"additional","affiliation":[{"name":"Department of Biology, The Gandhigram Rural Institute (Deemed to be University), Gandhigram, Dindigul 624302, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3703-5461","authenticated-orcid":false,"given":"Kwang-sun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Chemistry Institute for Functional Materials, Pusan National University, Busan 46241, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,4,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1007\/s40011-015-0574-1","article-title":"Chemical Constituents, Antioxidative and Antibacterial Properties of Medicinal Mushrooms Collected from Similipal Biosphere Reserve, Odisha, India","volume":"87","author":"Singdevsachan","year":"2017","journal-title":"Proc. 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