{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T15:55:01Z","timestamp":1785426901873,"version":"3.56.0"},"reference-count":171,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2026,5,31]],"date-time":"2026-05-31T00:00:00Z","timestamp":1780185600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pharmaceuticals"],"abstract":"<jats:p>Background: The genus Satureja L. (savory) includes approximately 200 aromatic herb and shrub species distributed worldwide. These plants are widely used in traditional and modern medicine, culinary practices, and agriculture. This review summarises knowledge on the traditional uses, phytochemistry, and pharmacological activities of Satureja species published between March 2014 and 2025. Methods: Peer-reviewed literature was searched on Web of Knowledge, PubMed, Scopus, and SciFinder using the keywords \u201cSatureja\u201d and \u201csavory.\u201d A total of 171 relevant articles were analyzed, focusing on ethnomedicinal use, chemical constituents, and pharmacological effects. Results: Recent ethnobotanical studies documented the use of local medicinal plants, including Satureja, in several European regions. Phytochemical research identified major groups of compounds such as essential oils, flavonoids, phenolic acids, jasmonates, di- and triterpenes, and steroids. Essential oils are the most studied and show high variability among species due to environmental and genetic factors. Pharmacological research largely highlights antimicrobial, antioxidant, and antitumor activities, as well as protective effects against chemotherapy-induced side effects. Additional studies report neurological benefits, including prevention of opioid analgesic tolerance, antiepileptic activity, and memory-enhancing effects. Satureja species have been the subject of various innovative developments aimed at preserving food quality, improving coating materials in the food industry, and developing new environmentally friendly biopesticides. Conclusions: Future research should prioritize the study of individual bioactive compounds, their mechanisms of action, and structure\u2013activity relationships. Advances in nanoformulations and modern extraction technologies offer promising directions to support the medicinal and food-industry applications of Satureja-derived products.<\/jats:p>","DOI":"10.3390\/ph19060875","type":"journal-article","created":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T01:08:02Z","timestamp":1780535282000},"page":"875","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Current Knowledge of the Genus Satureja: A Comprehensive Review of Its Traditional Use, Phytochemistry, Pharmacological Activity and Non-Medical Applications"],"prefix":"10.3390","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-2125-4349","authenticated-orcid":false,"given":"Marah","family":"Alburqan","sequence":"first","affiliation":[{"name":"Institute of Pharmacognosy, University of Szeged, E\u00f6tv\u00f6s Str. 6, 6720 Szeged, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katalin","family":"Veres","sequence":"additional","affiliation":[{"name":"Institute of Pharmacognosy, University of Szeged, E\u00f6tv\u00f6s Str. 6, 6720 Szeged, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2887-6392","authenticated-orcid":false,"given":"Judit","family":"Hohmann","sequence":"additional","affiliation":[{"name":"Institute of Pharmacognosy, University of Szeged, E\u00f6tv\u00f6s Str. 6, 6720 Szeged, Hungary"},{"name":"HUN-REN\u2013USZ Biologically Active Natural Products Research Group, University of Szeged, E\u00f6tv\u00f6s Str. 6, 6720 Szeged, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,5,31]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/(SICI)1099-1026(199801\/02)13:1<1::AID-FFJ672>3.0.CO;2-4","article-title":"Essential oils from two Peruvian Satureja species","volume":"13","author":"Senatore","year":"1998","journal-title":"Flav. Frag. J."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"375","DOI":"10.3109\/13880209.2015.1043560","article-title":"A pharmacological and phytochemical overview on Satureja","volume":"54","author":"Tepe","year":"2016","journal-title":"Pharm. Biol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.jep.2010.10.058","article-title":"Experimental study on Satureja montana as a treatment for premature ejaculation","volume":"133","author":"Zavatti","year":"2011","journal-title":"J. Ethnopharmacol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"536","DOI":"10.25135\/rnp.358.2207.2522","article-title":"Essential oil of Satureja montana L. from Herzegovina: Assessment of composition, antispasmodic, and antidiarrheal effects","volume":"17","author":"Drakul","year":"2023","journal-title":"Rec. Nat. Prod."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"454","DOI":"10.3923\/ijp.2010.346.353","article-title":"An update on pharmacology of Satureja species; from antioxidant, antimicrobial, antidiabetes and anti-hyperlipidemic to reproductive stimulation","volume":"6","author":"Momtaz","year":"2010","journal-title":"Int. J. Pharmacol."},{"key":"ref_6","unstructured":"Zargari, A. (1990). Medicinal Plants, University of Tehran Pub."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1530","DOI":"10.1111\/jam.13282","article-title":"Sensitivity of Candida albicans to essential oils: Are they an alternative to antifungal agents?","volume":"121","author":"Bona","year":"2016","journal-title":"J. Appl. Microbiol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.2174\/1389450116666150202161926","article-title":"Antimicrobial and antioxidant properties of Satureja montana L. and S. subspicata Vis. (Lamiaceae)","volume":"16","author":"Kremer","year":"2015","journal-title":"Curr. Drug. Targets"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"102562","DOI":"10.1016\/j.jksus.2023.102562","article-title":"Evaluation of some essential traditional medicinal plants for their potential free scavenging and antioxidant properties","volume":"35","author":"Jafri","year":"2023","journal-title":"J. King Saud. Univ. Sci."},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Miguel, M.G., da Silva, C.I., Farah, L., Castro Braga, F., and Figueiredo, A.C. (2020). Effect of essential oils on the release of TNF-\u03b1 and CCL2 by LPS-stimulated THP-1 Cells. Plants, 10.","DOI":"10.3390\/plants10010050"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"113969","DOI":"10.1016\/j.fct.2023.113969","article-title":"Novel landmarks on the journey from natural products to pharmaceutical formulations: Phytochemical, biological, toxicological and computational activities of Satureja hortensis L.","volume":"179","author":"Huwaimel","year":"2023","journal-title":"Food Chem. Toxicol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1093\/ecam\/nen018","article-title":"Effects of Satureja khuzestanica on serum glucose, lipids and markers of oxidative stress in patients with type 2 diabetes mellitus: A double-blind randomized controlled trial","volume":"7","author":"Rahimi","year":"2010","journal-title":"Evid. Based Complement. Altern. Med."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.jams.2016.04.003","article-title":"A Critical Overview on the Pharmacological and Clinical Aspects of Popular Satureja Species","volume":"9","author":"Jafari","year":"2016","journal-title":"J. Acupunct. Meridian Stud."},{"key":"ref_14","doi-asserted-by":"crossref","unstructured":"Ejaz, A., Waliat, S., Arshad, M.S., Khalid, W., Khalid, M.Z., Rasul Suleria, H.A., Luca, M.I., Mironeasa, C., Batariuc, A., and Ungureanu-Iuga, M. (2023). A comprehensive review of summer savory (Satureja hortensis L.): Promising ingredient for production of functional foods. Front. Pharmacol., 14.","DOI":"10.3389\/fphar.2023.1198970"},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"Fierascu, I., Dinu-Pirvu, C.E., Fierascu, R.C., Velescu, B.S., Anuta, V., Ortan, A., and Jinga, V. (2018). Phytochemical Profile and Biological Activities of Satureja hortensis L.: A Review of the Last Decade. Molecules, 23.","DOI":"10.3390\/molecules23102458"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1080\/10412905.2021.1885512","article-title":"Integrative review on ethnobotany, essential oil, phytochemical, agronomy, molecular and pharmacological properties of Satureja species","volume":"33","author":"Sefidkon","year":"2021","journal-title":"J. Essent. Oil Res."},{"key":"ref_17","first-page":"4513792","article-title":"Ethnobotanical Study of Medicinal Plants Used in Central Macedonia, Greece","volume":"1","author":"Tsioutsiou","year":"2019","journal-title":"Evid. Based Complement. Altern. Med."},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Cavalloro, V., Robustelli della Cuna, F.S., Quai, E., Preda, S., Bracco, F., Martino, E., and Collina, S. (2022). Walking around the Autonomous Province of Trento (Italy): An Ethnobotanical Investigation. Plants, 11.","DOI":"10.3390\/plants11172246"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.jep.2014.04.003","article-title":"Ethnobotanical study of medicinal plants of Sirjan in Kerman Province, Iran","volume":"154","author":"Nasab","year":"2014","journal-title":"J. Ethnopharmacol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"113186","DOI":"10.1016\/j.jep.2020.113186","article-title":"Traditional uses of autochthonous medicinal and ritual plants and other remedies for health in Eastern and South-Eastern Serbia","volume":"261","author":"Marin","year":"2020","journal-title":"J. Ethnopharmacol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1007\/s13197-017-2512-0","article-title":"Chemical composition and biological properties of Satureja avromanica Maroofi","volume":"54","author":"Abdali","year":"2017","journal-title":"J. Food. Sci. Technol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1080\/0972060X.2016.1216332","article-title":"Essential oil constituents and biological activities of different ecotypes of Satureja bachtiarica Bunge. as a traditional herbal drug in southwestern, Iran","volume":"19","author":"Alizadeh","year":"2016","journal-title":"J. Essent. Oil-Bear. Plants"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1007\/s11094-018-1766-9","article-title":"A Study on Essential Oil Chemical Compositions, Antioxidant, and Antimicrobial Activities of Native and Endemic Satureja Species Growing in Iran","volume":"52","author":"Jafari","year":"2018","journal-title":"Pharm. Chem. J."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"112719","DOI":"10.1016\/j.indcrop.2020.112719","article-title":"Bakhtiari savory (Satureja bachtiarica Bunge.) essential oil and its chemical profile, antioxidant activities, and leaf micromorphology under green and conventional extraction techniques","volume":"154","author":"Memarzadeh","year":"2020","journal-title":"Ind. Crop Prod."},{"key":"ref_25","first-page":"10021","article-title":"Chemical composition, insecticidal and allelopathic properties of EOs obtained from wild and cultivated Moroccan Satureja calamintha (L.)","volume":"3","author":"Abbad","year":"2023","journal-title":"J. Nat. Pestic. Res."},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Baghouz, A., Bouchelta, Y., Es-safi, I., El Brahimi, R., Imtara, H., AlZain, M.N., Noman, O.M., Shahat, A.A., and Guemmouh, R. (2024). Biocidal activity of Ziziphora hispanica L. and Satureja calamintha Scheele L. essential oils against the Callosobruchus maculatus (Fabricius) pest on cowpea seeds during storage. Front. Sustain. Food Syst., 8.","DOI":"10.3389\/fsufs.2024.1329100"},{"key":"ref_27","first-page":"213","article-title":"Chemical composition of the essential oil of Satureja calamintha subsp. Nepeta of west Algerian","volume":"6","author":"Bouzidi","year":"2018","journal-title":"Mor. J. Chem."},{"key":"ref_28","doi-asserted-by":"crossref","unstructured":"El Brahimi, R., El Barnossi, A., El Moussaoui, A., Chebaibi, M., Kachkoul, R., Baghouz, A., Nafidi, H.A., Salamatullah, A.M., Bourhia, M., and Bari, A. (2023). Phytochemistry and biological activities of essential oils from Satureja calamintha Nepeta. Separations, 10.","DOI":"10.3390\/separations10060344"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1080\/0972060X.2025.2589959","article-title":"Essential oil of Algerian endemic Satureja candidissima (Munby): A study of its biological activities","volume":"28","author":"Krimat","year":"2025","journal-title":"J. Essent. Oil-Bear. Plants"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"4043","DOI":"10.1080\/07391102.2024.2301742","article-title":"In silico and in vitro studies: Investigating the chemical composition, DFT, molecular docking, and dynamic simulation of Satureja candidissima (Munby) Briq essential oil as a potential antibacterial agent","volume":"43","author":"Saidi","year":"2025","journal-title":"J. Biomol. Struct. Dyn."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"559","DOI":"10.13005\/bpj\/3108","article-title":"Chemotaxonomic Characteristics of Satureja coerulea (Lamiaceae family) based on Analysis of its Bioactive Compounds","volume":"18","author":"Shanaida","year":"2025","journal-title":"Biomed. Pharmacol. J."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1080\/0972060X.2014.901603","article-title":"Seasonal variation in yield and composition of essential oil from Satureja cuneifolia Ten. growing wild in Lebanon","volume":"18","author":"Cazier","year":"2015","journal-title":"J. Essent. Oil-Bear. Plants"},{"key":"ref_33","first-page":"1944","article-title":"Chemical profile, in vitro pharmacological activity and Satureja cuneifolia Ten. evaluation of essential oil based on distillation time","volume":"34","author":"Temel","year":"2023","journal-title":"Int. J. Environ. Health Res."},{"key":"ref_34","doi-asserted-by":"crossref","unstructured":"Perrino, E.V., Valerio, F., Jallali, S., Trani, A., and Mezzapesa, G.N. (2021). Ecological and biological properties of Satureja cuneifolia Ten. and Thymus spinulosus Ten.: Two wild officinal species of conservation concern in Apulia (Italy). A Preliminary survey. Plants, 10.","DOI":"10.3390\/plants10091952"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1002\/ptr.5552","article-title":"Binary and tertiary mixtures of Satureja hortensis and Origanum vulgare essential oils as potent antimicrobial agents against Helicobacter pylori","volume":"30","author":"Lesjak","year":"2016","journal-title":"Phytother. Res."},{"key":"ref_36","doi-asserted-by":"crossref","unstructured":"Bimbirait\u0117-Survilien\u0117, K., Stankevi\u010dius, M., \u0160u\u0161tauskait\u0117, S., G\u0119gotek, A., Maru\u0161ka, A., Skrzydlewska, E., Barsteigien\u0117, Z., Aku\u0146eca, I., Raga\u017einskien\u0117, O., and Luko\u0161ius, A. (2021). Evaluation of chemical composition, radical scavenging and antitumor activities of Satureja hortensis L. herb extracts. Antioxididants, 10.","DOI":"10.3390\/antiox10010053"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1080\/13880209.2025.2572669","article-title":"Adjuvant potential of Satureja hortensis metabolites with antibiotics against Gram-positive and Gram-negative bacterial strains","volume":"63","author":"Alburqan","year":"2025","journal-title":"Pharm. Biol."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"e12527","DOI":"10.1111\/jfs.12527","article-title":"Effects of Thymus daenensis and Satureja hortensis L. essential oils on quality properties of Iranian Doogh","volume":"38","author":"Sasanian","year":"2018","journal-title":"J. Food. Saf."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"13","DOI":"10.14715\/cmb\/2017.64.15.3","article-title":"Antifungal activity of the essential oils of some medicinal plants against human and plant fungal pathogens","volume":"64","author":"Mafakheri","year":"2018","journal-title":"Cell. Mol. Biol."},{"key":"ref_40","doi-asserted-by":"crossref","unstructured":"Kim, J.E., Lee, J.E., Huh, M.J., Lee, S.C., Seo, S.M., Kwon, J.H., and Park, I.K. (2019). Fumigant antifungal activity via reactive oxygen species of Thymus vulgaris and Satureja hortensis essential oils and constituents against Raffaelea quercus-mongolicae and Rhizoctonia solani. Biomolecules, 9.","DOI":"10.3390\/biom9100561"},{"key":"ref_41","first-page":"1005","article-title":"Evaluation of genetic diversity of summer savory (Satureja hortensis L.) accessions based on morphological and phytochemical characteristics","volume":"36","author":"Fathi","year":"2021","journal-title":"Int. J. Med. Aromat. Plants Res."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"3711","DOI":"10.1080\/14786419.2022.2099390","article-title":"Comparison monoterpene and sesquiterpene, herbage yield of Satureja hortensis, Thymus vulgaris, and Salvia officinalis from the Fars province of Iran","volume":"37","author":"Yasuj","year":"2023","journal-title":"Nat. Prod. Res."},{"key":"ref_43","doi-asserted-by":"crossref","unstructured":"\u0160trbac, F., Bosco, A., Maurelli, M.P., Ratajac, R., Stojanovi\u0107, D., Simin, N., Or\u010di\u0107, D., Pu\u0161i\u0107, I., Krnjaji\u0107, S., and Sotiraki, S. (2022). Anthelmintic properties of essential oils to control gastrointestinal nematodes in sheep\u2014In vitro and in vivo studies. Vet. Sci., 9.","DOI":"10.3390\/vetsci9020093"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"e70733","DOI":"10.1002\/fsn3.70733","article-title":"Phytochemical Traits and Biological Activity of Satureja hortensis and Satureja macrantha as Culinary Spices Using GC\u2013MS\/MS and LC\u2013MS\/MS Techniques","volume":"13","author":"Elmdoustazar","year":"2025","journal-title":"Food Sci. Nutr."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"17812","DOI":"10.3390\/ijms160817812","article-title":"Composition, cytotoxic and antimicrobial activities of Satureja intermedia C.A. mey essential oil","volume":"16","author":"Iriti","year":"2015","journal-title":"Int. J. Mol. Sci."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"70","DOI":"10.5812\/ircmj.4989","article-title":"In vitro cytotoxic and antimicrobial activity of essential oil from Satureja intermedia","volume":"15","author":"Sadeghi","year":"2013","journal-title":"Iran. Red. Crescent. Med. J."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"19","DOI":"10.5812\/jjnpp-146767","article-title":"Chemical composition, Cholinesterase inhibitory effect and Cytotoxic activity study of essential oils extracted from different parts of Satureja isophylla Rech. f","volume":"19","author":"Aghaaliakbari","year":"2024","journal-title":"Jundishapur J. Nat. Pharm. Prod."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"183","DOI":"10.11646\/phytotaxa.441.2.5","article-title":"Satureja kermanica (Lamiaceae) a new species from south-east of Iran, inferred from molecular and morphological evidence","volume":"441","author":"Bordbar","year":"2020","journal-title":"Phytotaxa"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/j.foodchem.2019.03.076","article-title":"Development and characterization of biocomposite films made from kefiran, carboxymethyl cellulose and Satureja khuzestanica essential oil","volume":"289","author":"Hasheminya","year":"2019","journal-title":"Food. Chem."},{"key":"ref_50","first-page":"841","article-title":"Extraction and identification of the components of Thymbra spicata L. and Satureja khuzestanica Jamzad Oils native to Ilam province by headspace-solid phase microextraction (HS-SPME) and gas chromatography-mass spectrometry (GC-MS)","volume":"3","author":"Shahmohammadi","year":"2021","journal-title":"J. Med. Pharm. Chem. Res."},{"key":"ref_51","first-page":"e30034","article-title":"The antibacterial activity of Satureja khuzestanica essential oil against clinical isolates of E. coli","volume":"11","author":"Mahboubi","year":"2016","journal-title":"J. Nat. Pharm. Prod."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"111549","DOI":"10.1016\/j.indcrop.2019.111549","article-title":"Essential oil profile in relation to geographic origin and plant organ of Satureja kitaibelii Wierzb. ex Heuff","volume":"139","author":"Marin","year":"2019","journal-title":"Ind. Crop. Prod."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3897\/pharmacia.72.e146435","article-title":"Essential oil composition of Satureja kitaibelii Wierzb. ex Heuff. from the central Danubian plain, Bulgaria","volume":"72","author":"Gavrilov","year":"2025","journal-title":"Pharmacia"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"e202301418","DOI":"10.1002\/cbdv.202301418","article-title":"New facts on the antimicrobial Essential oil of Satureja kitaibelii","volume":"21","year":"2024","journal-title":"Chem. Biodivers."},{"key":"ref_55","doi-asserted-by":"crossref","unstructured":"Hudz, N., Makowicz, E., Shanaida, M., Bia\u0142o\u0144, M., Jasicka-Misiak, I., Yezerska, O., Svydenko, L., and Wieczorek, P.P. (2020). Phytochemical evaluation of tinctures and essential oil obtained from Satureja montana herb. Molecules, 25.","DOI":"10.3390\/molecules25204763"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1111\/lam.13659","article-title":"Bactericidal and antioxidant effects of essential oils from Satureja montana L., Myristica fragrans H. and Cymbopogon flexuosus","volume":"74","author":"Rezende","year":"2022","journal-title":"Lett. Appl. Microbiol."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"3143","DOI":"10.1080\/14786419.2018.1516661","article-title":"Comparison of chemical composition and antioxidant activities of two winter savory subspecies (Satureja montana subsp. variegata and Satureja montana subsp. montana) cultivated in Northern Italy","volume":"33","author":"Caprioli","year":"2019","journal-title":"Nat. Prod. Res."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"153","DOI":"10.24326\/asphc.2017.4.15","article-title":"Plant morphological parameters and yield of winter savory depending on the method of plantation establishment","volume":"16","year":"2017","journal-title":"Acta. Sci. Pol. Hortorum Cultus"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.micpath.2018.11.025","article-title":"Satureja montana L. essential oil and its antimicrobial activity alone or in combination with gentamicin","volume":"126","author":"Vitanza","year":"2019","journal-title":"Microb. Pathog."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.indcrop.2014.07.011","article-title":"Chemical composition, antimicrobial, and cytotoxic properties of five Lamiaceae essential oils","volume":"61","year":"2014","journal-title":"Ind. Crops Prod."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"e202500270","DOI":"10.1002\/cbdv.202500270","article-title":"Chemical Composition and Antifungal Effect of the Essential Oils of Thymus vulgaris L., Origanum vulgare L., and Satureja montana L. Against Clinical Isolates of Candida spp.","volume":"22","year":"2025","journal-title":"Chem. Biodivers."},{"key":"ref_62","first-page":"1122","article-title":"Evaluation of antibacterial potential of Satureja montana L., Ocimum basilicum L. and Salvia officinalis L. essential oils against reproductive tract pathogens in cattle and their toxicity impact on endometrial and kidney cells","volume":"45","author":"Ratajac","year":"2025","journal-title":"Pak. Vet. J."},{"key":"ref_63","doi-asserted-by":"crossref","unstructured":"Basha, E., Mamo\u00e7i, E., Sharma, A., Hodaj-\u00c7eliku, E., Zejnelhoxha, S., Medeleanu, M.L., Socaci, S.A., and Bisha, B. (2025). Essential Oils from Wild Albanian Lamiaceae: GC-MS Profiling, Biological Activity, and Enhanced Delivery via Nanoencapsulation. Molecules, 30.","DOI":"10.20944\/preprints202507.1209.v1"},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1007\/s40415-015-0215-1","article-title":"Assessment of EO constituents and main agro-morphological variability in Satureja mutica populations","volume":"39","author":"Karimi","year":"2016","journal-title":"Braz. J. Bot."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"120288","DOI":"10.1016\/j.ijpharm.2021.120288","article-title":"Core-shell chitosan\/PVA-based nanofibrous scaffolds loaded with Satureja mutica or Oliveria decumbens essential oils as enhanced antimicrobial wound dressing","volume":"597","author":"Barzegar","year":"2021","journal-title":"Int. J. Pharm."},{"key":"ref_66","doi-asserted-by":"crossref","unstructured":"Al-Maharik, N., and Jaradat, N. (2021). Phytochemical Profile, Antimicrobial, Cytotoxic, and Antioxidant Activities of Fresh and Air-Dried Satureja nabateorum Essential Oils. Molecules, 27.","DOI":"10.3390\/molecules27010125"},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"5757","DOI":"10.21873\/anticanres.11159","article-title":"Antioxidant and antiproliferative properties of the essential oils of Satureja thymbra and Satureja parnassica and their major constituents","volume":"36","author":"Fitsiou","year":"2016","journal-title":"Anticancer Res."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1007\/s13596-021-00596-1","article-title":"Study of compounds, cytotoxicity and biological activities of EO of Satureja rechingeri Jamzad","volume":"22","author":"Arman","year":"2022","journal-title":"Adv. Tradit. Med."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1007\/s00284-023-03604-6","article-title":"Effective Inhibition of Listeria monocytogenes Biofilm Formation by Satureja rechingeri Essential Oil: Mechanisms and Implications","volume":"81","author":"Maktabi","year":"2024","journal-title":"Curr. Microbiol."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"141629","DOI":"10.1016\/j.ijbiomac.2025.141629","article-title":"Development and characterization of Plantago major L. seeds mucilage-polyvinyl alcohol nano-biocomposite films incorporating Satureja sahendica Bornm. Essential oil nanoemulsion and zinc oxide nanoparticles","volume":"306","author":"Hasheminya","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"e1700239","DOI":"10.1002\/cbdv.201700239","article-title":"Phytochemical composition and antioxidant activities of the essential oil and extracts of Satureja subspicata\u00a0Vis. growing in Bosnia and Herzegovina","volume":"14","author":"Carev","year":"2017","journal-title":"Chem. Biodivers."},{"key":"ref_72","doi-asserted-by":"crossref","unstructured":"Khalil, N., El-Jalel, L., Yousif, M., and Gonaid, M. (2020). Altitude impact on the chemical profile and biological activities of Satureja thymbra L. essential oil. BMC Complement. Med. Ther., 20.","DOI":"10.1186\/s12906-020-02982-9"},{"key":"ref_73","doi-asserted-by":"crossref","unstructured":"Anastasiou, T.I., Mandalakis, M., Krigas, N., V\u00e9zignol, T., Lazari, D., Katharios, P., Dailianis, T., and Antonopoulou, E. (2020). Comparative Evaluation of essential oils from Medicinal-Aromatic Plants of Greece: Chemical Composition, Antioxidant Capacity and Antimicrobial Activity against Bacterial Fish Pathogens. Molecules, 25.","DOI":"10.3390\/molecules25010148"},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"e202402136","DOI":"10.1002\/cbdv.202402136","article-title":"Phytochemical Profiling and Bioactive Properties of Essential Oils from Endemic Palestinian Satureja thymbrifolia","volume":"22","author":"Jaradat","year":"2025","journal-title":"Chem. Biodivers."},{"key":"ref_75","doi-asserted-by":"crossref","unstructured":"Sierra-Quitian, A.G., Prieto-Rodr\u00edguez, J.A., and Pati\u00f1o-Ladino, O.J. (2025). Insecticidal Activity of Monoterpenoids Against Sitophilus zeamais Motschulsky and Tribolium castaneum Herbst: Preliminary Structure\u2013Activity Relationship Study. Int. J. Mol. Sci., 26.","DOI":"10.3390\/ijms26073407"},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1007\/s11130-019-0716-3","article-title":"Phytochemical properties of Satureja kitaibelii, potential natural antioxidants: A new insight","volume":"74","year":"2019","journal-title":"Plant. Food Hum. Nutr."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"21221","DOI":"10.1038\/s41598-022-25668-3","article-title":"Bioactivity and phenolics profile of aqueous and ethyl acetate extracts of Satureja kitaibelii Wierzb. ex Heuff. obtained by ultrasound-assisted extraction","volume":"12","year":"2022","journal-title":"Sci. Rep."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.fct.2018.05.001","article-title":"Summer savory (Satureja hortensis L.) extract: Phytochemical profile and modulation of cisplatin-induced liver, renal and testicular toxicity","volume":"118","author":"Boroja","year":"2018","journal-title":"Food Chem. Toxicol."},{"key":"ref_79","first-page":"674","article-title":"Quantification of secondary metabolites of Satureja pilosa (Lamiaceae) by LC-HRMS and evaluation of antioxidant and cholinergic activities","volume":"18","year":"2024","journal-title":"Rec. Nat. Prod."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.fitote.2015.06.012","article-title":"A new bioactive monoterpene\u2013flavonoid from Satureja khuzistanica","volume":"105","author":"Malmir","year":"2015","journal-title":"Fitoterapia"},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1016\/j.indcrop.2015.07.059","article-title":"Metabolite profiling for caffeic acid oligomers in Satureja biflora","volume":"76","author":"Moghadam","year":"2015","journal-title":"Ind. Crop. Prod."},{"key":"ref_82","first-page":"723","article-title":"Satureja subspicata and S. horvatii Extracts induce overexpression of the BCl-2 family of anti-apoptotic genes and reduce micronuclei frequency in mice","volume":"13","author":"Lojo","year":"2018","journal-title":"Nat. Prod. Commun."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1590\/1519-6984.224654","article-title":"Chemical compositions, radical scavenging capacities and antimicrobial activities in seeds of Satureja hortensis L. and Mentha spicata L. subsp. spicata from Turkey","volume":"81","author":"Emre","year":"2021","journal-title":"Braz. J. Biol."},{"key":"ref_84","first-page":"209","article-title":"Polyphenolic Content, Antioxidant Potential and Antimicrobial Activity of Satureja boissieri","volume":"37","author":"Aras","year":"2018","journal-title":"Iran. J. Chem. Chem. Eng."},{"key":"ref_85","doi-asserted-by":"crossref","unstructured":"Y\u0131ld\u0131z, A.N., \u00c7ar\u0131k\u00e7\u0131, S., Dirmenci, T., Kartal, M., G\u00fclcin, I., and G\u00f6ren, A.C. (2025). Secondary Metabolite Profiling of Satureja aintabensis P.H. Davis and Satureja spicigera (K. Koch) Boiss. by LC-HRMS and Evaluation of Antioxidant and Anticholinergic Activities. Life, 15.","DOI":"10.3390\/life15081272"},{"key":"ref_86","doi-asserted-by":"crossref","unstructured":"Teofilovi\u0107, B., Gligori\u0107, E., Nini\u0107, M., Vukmirovi\u0107, S., Gagi\u0107, \u017d., Mandi\u0107-Kova\u010devi\u0107, N., Tubi\u0107, B., \u0110ukanovi\u0107, \u0110., and Gruji\u0107-Leti\u0107, N. (2025). Green Extraction Combined with Chemometric Approach: Profiling Phytochemicals and Antioxidant Properties of Ten Species of the Lamiaceae Family. Separations, 12.","DOI":"10.3390\/separations12060155"},{"key":"ref_87","doi-asserted-by":"crossref","unstructured":"Samani, R.M., D\u2019Urso, G., Nazzaro, F., Fratianni, F., Masullo, M., and Piacente, S. (2024). Phytochemical Investigation and Biofilm-Inhibitory Activity of Bachtiari Savory (Satureja bachtiarica Bunge) Aerial Parts. Plants, 13.","DOI":"10.3390\/plants13010067"},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1016\/j.indcrop.2017.09.063","article-title":"Summer savory extracts prepared by novel extraction methods resulted in enhanced biological activity","volume":"109","year":"2017","journal-title":"Ind. Crop Prod."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"112640","DOI":"10.1016\/j.indcrop.2020.112640","article-title":"Using HPLC and multivariate analyses to investigate variations in the polyphenolic compounds as well as antioxidant and antiglycative activities of some Lamiaceae species native to Iran","volume":"154","author":"Rahimmalek","year":"2020","journal-title":"Ind. Crops Prod."},{"key":"ref_90","doi-asserted-by":"crossref","unstructured":"Ma\u0161kovi\u0107, J.M., Jakovljevi\u0107, V., \u017divkovi\u0107, V., Miti\u0107, M., Kur\u0107ubi\u0107, L.V., Miti\u0107, J., and Ma\u0161kovi\u0107, P.Z. (2024). Optimization of Ultrasound-Assisted Extraction of Phenolics from Satureja hortensis L. and Antioxidant Activity: Response Surface Methodology Approach. Processes, 12.","DOI":"10.3390\/pr12092042"},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"e202500328","DOI":"10.1002\/cbdv.202500328","article-title":"Enzyme inhibitory and antioxidant potential with phytochemical analysis of Satureja hasturkii H. Duman & Dirmenci: A new record from T\u00fcrkiye","volume":"22","author":"Buyukyildirim","year":"2025","journal-title":"Chem. Biodivers."},{"key":"ref_92","doi-asserted-by":"crossref","unstructured":"Abdelshafeek, K.A., Osman, A.F., Mouneir, S.M., Elhenawy, A.A., and Abdallah, W.E. (2023). Phytochemical profile, comparative evaluation of Satureja montana alcoholic extract for antioxidants, anti-inflammatory and molecular docking studies. BMC Complement. Med. Ther., 23.","DOI":"10.1186\/s12906-023-03913-0"},{"key":"ref_93","doi-asserted-by":"crossref","unstructured":"Jakupovi\u0107, L., Strawa, J.W., Ni\u017ei\u0107 Nodilo, L., Marijan, M., Hafner, A., Jakimiuk, K., Tomczykowa, M., Tomczyk, M., and Kon\u010di\u0107, M.Z. (2025). Cosmeceutical and Wound-Healing Activities of Green Hydroxypropyl-\u03b2-Cyclodextrin-Glycerol-Based Satureja montana Extracts. Molecules, 30.","DOI":"10.3390\/molecules30122638"},{"key":"ref_94","doi-asserted-by":"crossref","unstructured":"Pavlovi\u0107, O.M., Kolarevi\u0107, S., \u0110or\u0111evi\u0107, J., Jovanovi\u0107 Mari\u0107, J., Luni\u0107, T., Mandi\u0107, M., Kra\u010dun Kolarevi\u0107, M., \u017divkovi\u0107, J., Alimpi\u0107 Aradski, A., and Marin, P.D. (2021). A study of phytochemistry, genoprotective activity, and antitumor effects of extracts of the selected Lamiaceae species. Plants, 10.","DOI":"10.3390\/plants10112306"},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"e202302109","DOI":"10.1002\/cbdv.202302109","article-title":"Variation in Phenolic Content, Antioxidant Activity and Alpha-amylase and Acetylcholinesterase Inhibitory Capacities of Different Extracts from Tunisian Satureja barceloi (Willk) L.","volume":"21","author":"Raadani","year":"2024","journal-title":"Chem. Biodivers."},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"150","DOI":"10.7546\/CRABS.2022.01.18","article-title":"GC-MS-based metabolite profiling of wild and in vitro growing plants of Satureja montana L.","volume":"75","author":"Vrancheva","year":"2022","journal-title":"C. R. Acad. Bulg. Sci."},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"e2400823","DOI":"10.1002\/ardp.202400823","article-title":"Depsides from Origanum dictamnus and Satureja pilosa as selective inhibitors of carbonic anhydrases: Isolation, structure elucidation, X-ray crystallography","volume":"358","author":"Paloukopoulou","year":"2025","journal-title":"Arch. Pharm."},{"key":"ref_98","doi-asserted-by":"crossref","unstructured":"\u0160imunovi\u0107, K., Bucar, F., Klan\u010dnik, A., Pompei, F., Paparella, A., and Smole Mo\u017eina, S. (2020). In vitro effect of the common culinary herb winter savory (Satureja montana) against the infamous food pathogen Campylobacter jejuni. Foods, 9.","DOI":"10.3390\/foods9040537"},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.phytochem.2019.05.011","article-title":"Isolation and functional characterization of an antifungal hydrophilic peptide, Skh-AMP1, derived from Satureja khuzistanica leaves","volume":"164","author":"Khani","year":"2019","journal-title":"Phytochemistry"},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"235","DOI":"10.15171\/apb.2018.028","article-title":"Phytochemical synthesis of silver nanoparticles by two techniques using Saturaja rechengri Jamzad extract: Identifying and comparing in vitro anti-proliferative activities","volume":"8","author":"Narchin","year":"2018","journal-title":"Adv. Pharm. Bull."},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1080\/01480545.2024.2362180","article-title":"Enhanced antibacterial and genoprotective properties of nanoliposomal Satureja hortensis L. essential oil","volume":"48","author":"Cagal","year":"2025","journal-title":"Drug. Chem. Toxicol."},{"key":"ref_102","doi-asserted-by":"crossref","unstructured":"Yuan, Y., Hui, X., Liu, Z., Sun, J., Raka, R.N., Xiao, J., Zhang, Z., and Wu, H. (2025). Investigation of differential multi-mode antibacterial mechanisms of essential oils of Satureja montana L. and Leptospermum scoparium JR Forst. & G. Forst. against Porphyromonas gingivalis. BMC Complement. Med. Ther., 25.","DOI":"10.1186\/s12906-025-05007-5"},{"key":"ref_103","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1111\/jam.13639","article-title":"Antibacterial, antibiofilm and antiquorum sensing effects of Thymus daenensis and Satureja hortensis essential oils against Staphylococcus aureus isolates","volume":"124","author":"Sharifi","year":"2018","journal-title":"J. Appl. Microbiol."},{"key":"ref_104","doi-asserted-by":"crossref","unstructured":"Maravi\u0107-Vlahovi\u010dek, G., Kindl, M., Andri\u010devi\u0107, K., Obrani\u0107, S., and Vladimir-Kne\u017eevi\u0107, S. (2025). Modulatory Effects of Satureja montana L. Essential Oil on Biofilm Formation and Virulence Factors of Pseudomonas aeruginosa. Pharmaceuticals, 18.","DOI":"10.3390\/ph18091269"},{"key":"ref_105","doi-asserted-by":"crossref","unstructured":"Mandalakis, M., Anastasiou, T.I., Martou, N., Keisaris, S., Greveniotis, V., Katharios, P., Lazari, D., Krigas, N., and Antonopoulou, E. (2021). Antibacterial effects of essential oils of seven medicinal-aromatic plants against the fish pathogen Aeromonas veronii bv. sobria: To blend or not to blend?. Molecules, 26.","DOI":"10.3390\/molecules26092731"},{"key":"ref_106","doi-asserted-by":"crossref","first-page":"e12350","DOI":"10.1111\/hel.12350","article-title":"Binary mixture of Satureja hortensis and Origanum vulgare subsp. hirtum essential oils: In vivo therapeutic efficiency against Helicobacter pylori infection","volume":"22","author":"Harmati","year":"2017","journal-title":"Helicobacter"},{"key":"ref_107","doi-asserted-by":"crossref","unstructured":"Fratini, F., Pecorini, C., Resci, I., Copelotti, E., Nocera, F.P., Najar, B., and Mancini, S. (2025). Evaluation of the Synergistic Antimicrobial Activity of Essential Oils and Cecropin A Natural Peptide on Gram-Negative Bacteria. Animals, 15.","DOI":"10.3390\/ani15020282"},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"122181","DOI":"10.1016\/j.ijpharm.2022.122181","article-title":"Interaction of a natural compound nanoemulsion with Gram negative and Gram positive bacterial membrane; a mechanism based study using a microfluidic chip and DESI technique","volume":"626","author":"Alvand","year":"2022","journal-title":"Int. J. Pharm."},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"114296","DOI":"10.1016\/j.colsurfb.2024.114296","article-title":"Enhancing leachate management with antibacterial nanocomposites incorporating plant-based carbon dots and Satureja khuzestanica essential oils","volume":"245","author":"Rezaei","year":"2025","journal-title":"Colloids. Surf. B"},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"40291","DOI":"10.1038\/s41598-025-24039-y","article-title":"Antifungal efficacy of plant essential oil nanoemulsions against cucumber powdery mildew","volume":"15","author":"Abbasi","year":"2025","journal-title":"Sci. Rep."},{"key":"ref_111","doi-asserted-by":"crossref","unstructured":"Vanti, G., Tomou, E.M., Stojkovi\u0107, D., \u0106iri\u0107, A., Bilia, A.R., and Skaltsa, H. (2021). Nanovesicles loaded with Origanum onites and Satureja thymbra essential oils and their activity against food-borne pathogens and spoilage microorganisms. Molecules, 26.","DOI":"10.3390\/molecules26082124"},{"key":"ref_112","doi-asserted-by":"crossref","first-page":"35699","DOI":"10.1038\/s41598-025-19622-2","article-title":"Chemical profile and bioactivity of essential oils from five Turkish thyme species against white mold fungal disease agent Sclerotinia sclerotiorum","volume":"15","author":"Maral","year":"2025","journal-title":"Sci. Rep."},{"key":"ref_113","doi-asserted-by":"crossref","unstructured":"B\u01ceie\u015f, M.H., Gy\u00f6rke, A., Cotu\u0163iu, V.D., Boros, Z., Cozma-Petru\u021b, A., Filip, L., Vlase, L., Vlase, A.M., Cri\u015fan, G., and Sp\u00eenu, M. (2023). The in vitro anticoccidial activity of some herbal extracts against Eimeria spp. oocysts isolated from piglets. Pathogens, 12.","DOI":"10.3390\/pathogens12020258"},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1007\/s11686-023-00780-0","article-title":"Investigating the Effect of Satureja khuzestanica Essential oil on MDR1 Gene Expression in Leishmania major","volume":"69","author":"Jahanshahi","year":"2024","journal-title":"Acta. Parasitol."},{"key":"ref_115","doi-asserted-by":"crossref","unstructured":"Les, F., Galiffa, V., C\u00e1sedas, G., Moliner, C., Maggi, F., L\u00f3pez, V., and G\u00f3mez-Rinc\u00f3n, C. (2024). Essential Oils of Two Subspecies of Satureja montana L. against Gastrointestinal Parasite Anisakis simplex and Acetylcholinesterase Inhibition. Molecules, 29.","DOI":"10.3390\/molecules29194640"},{"key":"ref_116","doi-asserted-by":"crossref","unstructured":"\u0160trbac, F., Krnjaji\u0107, S., Ratajac, R., Rinaldi, L., Musella, V., Castagna, F., Stojanovi\u0107, D., Simin, N., Or\u010di\u0107, D., and Bosco, A. (2025). Anthelmintic activity of winter savory (Satureja montana L.) essential oil against gastrointestinal nematodes of sheep. BMC Vet. Res., 21.","DOI":"10.1186\/s12917-025-04771-3"},{"key":"ref_117","first-page":"347","article-title":"Anti-Trichomonas vaginalis activities and apoptotic effects of some Iranian medicinal plants","volume":"35","author":"Mahmoudvand","year":"2018","journal-title":"Trop. Biomed."},{"key":"ref_118","doi-asserted-by":"crossref","first-page":"e00871","DOI":"10.1016\/j.btre.2024.e00871","article-title":"Protective role of savory essential oil on vital organs in rats against deleterious effects induced by lead acetate","volume":"45","author":"Aboubaker","year":"2025","journal-title":"Biotechnol. Rep."},{"key":"ref_119","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1080\/15321819.2019.1629592","article-title":"Satureja hortensis induces cell death and inhibited cell cycle progression in K562 myelogenous and Jurkat T cell leukemia cell lines","volume":"40","author":"Asadipour","year":"2019","journal-title":"J. Immunoass. Immunochem."},{"key":"ref_120","doi-asserted-by":"crossref","unstructured":"Vladi\u0107, J., \u0106ebovi\u0107, T., Vidovi\u0107, S., and Joki\u0107, S. (2020). Evaluation of anticancer activity of Satureja montana supercritical and spray-dried extracts on Ehrlich\u2019s Ascites carcinoma bearing mice. Plants, 9.","DOI":"10.3390\/plants9111532"},{"key":"ref_121","doi-asserted-by":"crossref","first-page":"12490","DOI":"10.1038\/s41598-024-63205-6","article-title":"Antioxidant, anti-amylase, anti-lipase, and efficiency of Satureja fatty acid on the anti-inflammatory parameters in lipopolysaccharide-stimulated macrophage through Nrf2\/NF-kB\/NADH oxidase pathway","volume":"14","author":"Obeidnejad","year":"2024","journal-title":"Sci. Rep."},{"key":"ref_122","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.5530\/pres.20252194","article-title":"Investigating the Expression of Apoptosis and Metastasis Genes in Satureja khuzistanica along with Nisin and Doxorubicin in Colorectal Cancer","volume":"17","author":"Kheiri","year":"2025","journal-title":"Pharmacog. Res."},{"key":"ref_123","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1080\/15321819.2018.1480495","article-title":"Inhibition of LPS-induced inflammatory responses by Satureja hortensis extracts in J774.1 macrophages","volume":"39","author":"Farzaneh","year":"2018","journal-title":"J. Immunoass. Immunochem."},{"key":"ref_124","doi-asserted-by":"crossref","first-page":"31866","DOI":"10.1038\/srep31866","article-title":"The anti-inflammatory properties of Satureja khuzistanica Jamzad EO attenuate the effects of traumatic brain injuries in rats","volume":"6","author":"Abbasloo","year":"2016","journal-title":"Sci. Rep."},{"key":"ref_125","first-page":"114","article-title":"Anti-inflammatory and in vitro antioxidant activities of Satureja montana dry extract","volume":"66","author":"Vilmosh","year":"2024","journal-title":"Fol. Med."},{"key":"ref_126","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1111\/and.12421","article-title":"Cytoprotective and anti-apoptotic effects of Satureja khuzestanica essential oil against busulfan-mediated sperm damage and seminiferous tubules destruction in adult male mice","volume":"48","author":"Nasimi","year":"2016","journal-title":"Andrologia"},{"key":"ref_127","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.cbi.2014.11.001","article-title":"Protective effect of Satureja montana extract on cyclophosphamide-induced testicular injury in rats","volume":"224","author":"Shahin","year":"2014","journal-title":"Chem. Biol. Interact."},{"key":"ref_128","first-page":"7605","article-title":"The effect of mucoadhesive gel containing Satureja hortensis extract 1% on severity of chemotherapy-induced mucositis pain in children: A randomized clinical trial","volume":"6","author":"Bostanabad","year":"2018","journal-title":"Int. J. Pediatr."},{"key":"ref_129","doi-asserted-by":"crossref","unstructured":"Coban, F., Lan, Y., Yetisgin, G., Yuca, H., Ayd\u0131n, B., Ang\u0131n, H., Demirci, B., and Karakaya, S. (2025). Phytochemical composition and bioactivities of Satureja montana L. and Satureja hortensis L.: Culinary herbs with antidiabetic, anticholinesterase, and antioxidant potential. PLoS ONE, 20.","DOI":"10.1371\/journal.pone.0332178"},{"key":"ref_130","doi-asserted-by":"crossref","unstructured":"Roosta, S., Ghasemi, F., Mokhayeri, Y., Choobkar, S., Nikbakht, M.R., and Falahi, E. (2024). Effects of Satureja Khuzestanica supplementation on glycemic indices and lipid profile in type-2 diabetes patients: A randomized controlled clinical-trial. BMC Complement. Med. Ther., 24.","DOI":"10.1186\/s12906-024-04384-7"},{"key":"ref_131","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1111\/jpn.13220","article-title":"Independent and combined effects of Satureja khuzistanica essential oils and acetic acid on prevalence and intensity of fatty liver syndrome in broiler chickens","volume":"104","author":"Mirderikvandi","year":"2020","journal-title":"J. Anim. Physiol. Anim. Nutr."},{"key":"ref_132","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1007\/s11011-015-9773-y","article-title":"Satureja bachtiarica ameliorate beta-amyloid induced memory impairment, oxidative stress and cholinergic deficit in animal model of Alzheimer\u2019s disease","volume":"31","author":"Soodi","year":"2016","journal-title":"Metab. Brain. Dis."},{"key":"ref_133","doi-asserted-by":"crossref","first-page":"2909","DOI":"10.1111\/are.12742","article-title":"Extracts of Oliviera decumbens and Satureja khuzestanica as immunostimulants affect some innate immunity indices of Cyprinus carpio against Aeromonas hydrophila infection","volume":"47","author":"Alishahi","year":"2015","journal-title":"Aquac. Res."},{"key":"ref_134","doi-asserted-by":"crossref","unstructured":"S\u00e1nchez-Quintero, M.J., Delgado, J., Medina-Vera, D., Becerra-Mu\u00f1oz, V.M., Queipo-Ortu\u00f1o, M.I., Est\u00e9vez, M., Plaza-Andrades, I., Rodr\u00edguez-Capit\u00e1n, J., S\u00e1nchez, P.L., and Crespo-Leiro, M.G. (2022). Beneficial effects of essential oils from the Mediterranean diet on gut microbiota and their metabolites in ischemic heart disease and type-2 diabetes mellitus. Nutrients, 14.","DOI":"10.3390\/nu14214650"},{"key":"ref_135","doi-asserted-by":"crossref","unstructured":"Demyashkin, G., Tokov, A., Belokopytov, D., Shchekin, V., Borovaya, T., Lukash, D., Yuferov, D., Kulchenko, N., Tarasov, V., and Blinova, E. (2025). Effects of Satureja montana L. and Origanum vulgare L. Hydrolates in Rabbit Burn Wound Model: Evaluation of Inflammatory, Antioxidant Activity, and Pro-Regenerative Properties in the Skin. Int. J. Mol. Sci., 26.","DOI":"10.3390\/ijms26178628"},{"key":"ref_136","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1016\/j.ijbiomac.2020.06.086","article-title":"Development of Satureja cuneifolia-loaded sodium alginate\/polyethylene glycol scaffolds produced by 3D-printing technology as a diabetic wound dressing material","volume":"161","author":"Ilhan","year":"2020","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_137","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/s11418-013-0796-6","article-title":"Satureja khuzestanica prevents the development of morphine analgesic tolerance through suppression of spinal glial cell activation in rats","volume":"69","author":"Ebrahimi","year":"2015","journal-title":"J. Nat. Med."},{"key":"ref_138","doi-asserted-by":"crossref","first-page":"465","DOI":"10.32598\/bcn.2021.1665.1","article-title":"Effects of Satureja bachtiarica essential oil in preventing seizure in pentylenetetrazol-kindled mice","volume":"13","author":"Rabiei","year":"2022","journal-title":"Basic Clin. Neurosci."},{"key":"ref_139","doi-asserted-by":"crossref","first-page":"103236","DOI":"10.1016\/j.jksus.2024.103236","article-title":"Evaluation of the cardioprotective activity of summer savory (Satureja hortensis L.) extract in experimental rats with Isoproterenol-induced myocardial infarction","volume":"36","author":"Muthukumar","year":"2024","journal-title":"J. King Saud. Univ. Sci."},{"key":"ref_140","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.ijbiomac.2017.08.003","article-title":"Application of tragacanth gum impregnated with Satureja khuzistanica essential oil as a natural coating for enhancement of postharvest quality and shelf life of button mushroom (Agaricus bisporus)","volume":"106","author":"Nasiri","year":"2018","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_141","doi-asserted-by":"crossref","first-page":"5","DOI":"10.5812\/jkums.69640","article-title":"The Effects of Satureja hortensis L. essential oil on the Growth and Survival of Salmonella typhimorium in Minced Poultry Meat During Refrigerated Storage","volume":"22","author":"Azimi","year":"2018","journal-title":"J. Kermanshah. Univ. Med. Sci."},{"key":"ref_142","doi-asserted-by":"crossref","unstructured":"Toplu, Y., and \u00d6nl\u00fc, H. (2025). Anti-Listerial Effects of Satureja hortensis Essential Oils in Ready-to-Eat Poultry Meat Stored at Different Temperatures. Microbiol. Res., 16.","DOI":"10.3390\/microbiolres16090195"},{"key":"ref_143","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/s00425-025-04837-4","article-title":"Satureja montana L. essential oil and montmorillonite nanoclay modulate the phenylpropanoid pathway and polyphenols biosynthesis of tomato plants suffering from bacterial spot disease","volume":"262","author":"Guido","year":"2025","journal-title":"Planta"},{"key":"ref_144","doi-asserted-by":"crossref","first-page":"e202402093","DOI":"10.1002\/cbdv.202402093","article-title":"Chemical Composition and Synergistic Antimicrobial Effects of Essential Oils From Four Commonly Used Satureja Species in Combination With Two Conventional Antibiotics","volume":"22","author":"Abbad","year":"2025","journal-title":"Chem. Biodivers."},{"key":"ref_145","first-page":"672","article-title":"Amelioration of altered antioxidant enzyme activity by Satureja khuzistanica essential oil in alloxan-induced diabetic rats","volume":"12","author":"Ahmadvand","year":"2014","journal-title":"Chin. J. Nat. Med."},{"key":"ref_146","doi-asserted-by":"crossref","first-page":"121032","DOI":"10.1016\/j.ijpharm.2021.121032","article-title":"A microfluidic chip for visual investigation of the interaction of nanoemulsion of Satureja khuzistanica essential oil and a model gram-negative bacteria","volume":"607","author":"Alvand","year":"2021","journal-title":"Int. J. Pharm."},{"key":"ref_147","doi-asserted-by":"crossref","first-page":"213","DOI":"10.56499\/jppres19.611_7.3.213","article-title":"A screening of anti breast cancer effects and antioxidant activity of twenty medicinal plants gathered from Chaharmahal va Bakhtyari province","volume":"7","author":"Lorigooini","year":"2019","journal-title":"Iran. J. Pharm. Pharmacogn. Res."},{"key":"ref_148","first-page":"31","article-title":"A comparative study on the analgesic properties of five members of Lamiaceae family using two pain models","volume":"5","author":"Asghari","year":"2018","journal-title":"Res. J. Pharm."},{"key":"ref_149","doi-asserted-by":"crossref","unstructured":"B\u0103ie\u015f, M.-H., Gherman, C., Boros, Z., Olah, D., Vlase, A.-M., Cozma-Petru\u021b, A., Gy\u00f6rke, A., Miere, D., Vlase, L., and Cri\u0219an, G. (2022). The Effects of Allium sativum L., Artemisia absinthium L., Cucurbita pepo L., Coriandrum sativum L., Satureja hortensis L. and Calendula officinalis L. on the Embryogenesis of Ascaris suum Eggs during an In Vitro Experimental Study. Pathogens, 11.","DOI":"10.3390\/pathogens11091065"},{"key":"ref_150","doi-asserted-by":"crossref","unstructured":"Bartels, N., Argyropoulou, A., Al-Ahmad, A., Hellwig, E., Skaltsounis, A.L., Wittmer, A., Vach, K., and Karygianni, L. (2025). Antibiofilm potential of plant extracts: Inhibiting oral microorganisms and Streptococcus mutans. Front. Dent. Med., 6.","DOI":"10.3389\/fdmed.2025.1535753"},{"key":"ref_151","doi-asserted-by":"crossref","first-page":"21917","DOI":"10.1038\/s41598-025-08856-9","article-title":"Effect of nano liposomal herbal extracts against biofilm formation and adherence of Streptococcus mutans","volume":"15","author":"Baseri","year":"2025","journal-title":"Sci. Rep."},{"key":"ref_152","doi-asserted-by":"crossref","unstructured":"Cagnoli, G., Bertelloni, F., and Ebani, V.V. (2024). In Vitro Antibacterial Activity of Essential Oils from Origanum vulgare, Satureja montana, Thymus vulgaris, and Their Blend Against Necrotoxigenic (NTEC), Enteropathogenic (EPEC), and Shiga-Toxin Producing Escherichia coli (STEC) Isolates. Pathogens, 13.","DOI":"10.3390\/pathogens13121077"},{"key":"ref_153","doi-asserted-by":"crossref","first-page":"e4032","DOI":"10.17795\/ijcp-4032","article-title":"An Investigation of the growth inhibitory capacity of several medicinal plants from Iran on tumor cell lines","volume":"8","author":"Esmaeilbeig","year":"2015","journal-title":"Iran. J. Cancer Prev."},{"key":"ref_154","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/j.pharma.2024.01.005","article-title":"Antioxidant and cytotoxicity activity of a nanoemulsion from Satureja kermanica (Lamiaceae)","volume":"82","author":"Hassanabadi","year":"2024","journal-title":"Ann. Pharm. Fr."},{"key":"ref_155","doi-asserted-by":"crossref","unstructured":"Hickl, J., Argyropoulou, A., Al-Ahmad, A., Hellwig, E., Skaltsounis, A.L., Wittmer, A., Vach, K., and Karygianni, L. (2024). Unleashing nature\u2019s defense: Potent antimicrobial power of plant extracts against oral pathogens and Streptococcus mutans biofilms. Front. Oral. Health, 5.","DOI":"10.3389\/froh.2024.1469174"},{"key":"ref_156","first-page":"1466","article-title":"Evaluation of the antioxidant effects and cytotoxic potential of selected herbs used in traditional medicine","volume":"29","author":"Jovanova","year":"2019","journal-title":"J. Anim. Plant Sci."},{"key":"ref_157","doi-asserted-by":"crossref","first-page":"2007","DOI":"10.1007\/s13738-018-1398-8","article-title":"Otentiality of independent component regression in assessment of the peaks responsible for antimicrobial activity of Satureja hortensis L. and Oliveria decumbens Vent. using GC\u2013MS","volume":"15","author":"Masoum","year":"2018","journal-title":"J. Iran. Chem. Soc."},{"key":"ref_158","first-page":"169","article-title":"Satureja khuzestanica mediated synthesis of silver nanoparticles and its evaluation of antineoplastic activity to combat colorectal cancer cell line","volume":"19","author":"Mirhosseini","year":"2020","journal-title":"Iran. J. Pharm. Res."},{"key":"ref_159","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1080\/08957959.2020.1830079","article-title":"Optimization of antioxidant activity and bioactive compounds extraction of winter savory leaves by high hydrostatic pressure","volume":"40","author":"Moreira","year":"2020","journal-title":"High Press. Res."},{"key":"ref_160","first-page":"5","article-title":"Inhibition test of heme detoxification (ITHD) as an approach for detecting antimalarial agents in medicinal plants","volume":"5","author":"Mosaddegh","year":"2018","journal-title":"Res. J. Pharmacogn."},{"key":"ref_161","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1016\/j.ijbiomac.2022.09.044","article-title":"Chitosan nanocomposite incorporated Satureja kermanica essential oil and extract: Synthesis, characterization and antifungal assay","volume":"221","author":"Payandeh","year":"2022","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_162","doi-asserted-by":"crossref","unstructured":"Pereira, G., and Faria, J.M.S. (2024). Activity of Satureja montana Allelochemical Volatiles Against the Pinewood Nematode. Chem. Proc., 16.","DOI":"10.3390\/ecsoc-28-20154"},{"key":"ref_163","doi-asserted-by":"crossref","first-page":"34816","DOI":"10.1038\/s41598-025-18680-w","article-title":"Combined antibacterial effect of essential oils from three Indian medicinal plants and antibiotic tetracycline on MRSA using simplex centroid mixture design","volume":"15","author":"Raikwar","year":"2025","journal-title":"Sci. Rep."},{"key":"ref_164","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1080\/0972060X.2015.1060872","article-title":"Satureja hortensis L. methanolic extract and essential oil exhibit antitumor activity","volume":"19","author":"Ramezani","year":"2016","journal-title":"J. Essent. Oil Bear. Plants"},{"key":"ref_165","first-page":"93","article-title":"In vitro evaluation of acaricidal efficacy of selected essential oils against Dermanyssus gallinae","volume":"44","author":"Ratajac","year":"2024","journal-title":"Pak. Vet. J."},{"key":"ref_166","doi-asserted-by":"crossref","first-page":"21267","DOI":"10.1038\/s41598-025-06160-0","article-title":"Antibacterial activity of a conventional hydrogel and a nanoparticle based hydrogel containing Satureja khuzestanica essential oil","volume":"15","author":"Saboori","year":"2025","journal-title":"Sci. Rep."},{"key":"ref_167","first-page":"200","article-title":"Antioxidant activity of essential oils obtained from aerial part of some Lamiaceae species","volume":"12","author":"Shanaida","year":"2018","journal-title":"Int. J. Green Pharm."},{"key":"ref_168","doi-asserted-by":"crossref","unstructured":"Valentini, F., Colasanti, I.A., Zaratti, C., Filimon, D., Macchia, A., Neri, A., Relucenti, M., Reverberi, M., Allegrini, I., and Guerriero, E. (2025). TiO2 and CaCO3 Microparticles Produced in Aqueous Extracts from Satureja montana: Synthesis, Characterization, and Preliminary Antimicrobial Test. Molecules, 30.","DOI":"10.3390\/molecules30204138"},{"key":"ref_169","doi-asserted-by":"crossref","first-page":"31125","DOI":"10.1038\/s41598-024-82380-0","article-title":"Antifungal activity of essential oils and their potential synergistic effect with amphotericin B","volume":"14","author":"Yuan","year":"2024","journal-title":"Sci. Rep."},{"key":"ref_170","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1089\/jmf.2013.0052","article-title":"Antibacterial and antigelatinolytic effects of Satureja hortensis L. essential oil on epithelial cells exposed to Fusobacterium nucleatum","volume":"18","author":"Keskin","year":"2015","journal-title":"J. Med. Food."},{"key":"ref_171","doi-asserted-by":"crossref","first-page":"e17766","DOI":"10.5812\/jjm.17766","article-title":"Antimicrobial activity of seven essential oils from Iranian aromatic plants against common causes of oral infections","volume":"8","author":"Zomorodian","year":"2015","journal-title":"Jundishapur J. Microbiol."}],"container-title":["Pharmaceuticals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1424-8247\/19\/6\/875\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T01:17:22Z","timestamp":1780535842000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1424-8247\/19\/6\/875"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,31]]},"references-count":171,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2026,6]]}},"alternative-id":["ph19060875"],"URL":"https:\/\/doi.org\/10.3390\/ph19060875","relation":{},"ISSN":["1424-8247"],"issn-type":[{"value":"1424-8247","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,31]]}}}