{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T04:07:17Z","timestamp":1780632437067,"version":"3.54.1"},"reference-count":102,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T00:00:00Z","timestamp":1780531200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pharmaceuticals"],"abstract":"<jats:p>Sonchus asper (L.) Hill is a widely distributed plant traditionally used as both a food source and a medicinal herb. In recent years, increasing interest in natural, safe, and effective cosmetic ingredients has highlighted the potential of plant-derived bioactive compounds. This review provides an overview of the biological properties of S. asper, with particular emphasis on its relevance in cosmetic applications. The plant is characterized by a rich profile of primary and secondary metabolites, including amino acids, fatty acids, vitamins, phenolic acids, flavonoids, coumarins, and terpenoids. These compounds contribute to a broad spectrum of biological activities, such as strong free radical scavenging activity, modulation of inflammatory pathways, and inhibition of the growth of selected skin-associated pathogens, suggesting its potential as a multifunctional cosmetic ingredient.<\/jats:p>","DOI":"10.3390\/ph19060890","type":"journal-article","created":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T03:24:33Z","timestamp":1780629873000},"page":"890","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Sonchus asper and Its Potential in Cosmetics\u2014A Review"],"prefix":"10.3390","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2995-4065","authenticated-orcid":false,"given":"Dorota","family":"Kasprzak","sequence":"first","affiliation":[{"name":"Department of Beauty Sciences, Faculty of Health Sciences, Vincent Pol University, 2 Choiny Str., 20-816 Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5212-7463","authenticated-orcid":false,"given":"Natalia","family":"Dycha","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy with Medicinal Plants Garden, Medical University of Lublin, 1 Chodzki Str., 20-093 Lublin, Poland"},{"name":"Doctoral School, Medical University of Lublin, 7 Chod\u017aki Str., 20-093 Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2244-4118","authenticated-orcid":false,"given":"Magdalena","family":"Michalak-Tomczyk","sequence":"additional","affiliation":[{"name":"Department of Physiology and Toxicology, Faculty of Medicine, The John Paul II Catholic University of Lublin, Konstantyn\u00f3w 1I Str., 20-708 Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Wawruszak","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biology, Medical University of Lublin, 1 Chodzki Str., 20-093 Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magdalena","family":"Zdzieb\u0142o","sequence":"additional","affiliation":[{"name":"Branch in Sandomierz, Jan Kochanowski University in Kielce, 13a Schinzla Str., 27-600 Sandomierz, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7076-600X","authenticated-orcid":false,"given":"Wirginia","family":"Kukula-Koch","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy with Medicinal Plants Garden, Medical University of Lublin, 1 Chodzki Str., 20-093 Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9961-4226","authenticated-orcid":false,"given":"Grazyna","family":"Ginalska","sequence":"additional","affiliation":[{"name":"Department of Beauty Sciences, Faculty of Health Sciences, Vincent Pol University, 2 Choiny Str., 20-816 Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,6,4]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e70457","DOI":"10.1002\/mnfr.70457","article-title":"Dietary Phytochemicals and Herbal Medicines Re-Program Cellular Networks by Targeting Key Transcription Factors","volume":"70","author":"Lindenmaier","year":"2026","journal-title":"Mol. 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