{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T05:23:27Z","timestamp":1773725007798,"version":"3.50.1"},"reference-count":154,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2023,4,5]],"date-time":"2023-04-05T00:00:00Z","timestamp":1680652800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001843","name":"Science and Engineering Research Board","doi-asserted-by":"publisher","award":["SERB Act 2008"],"award-info":[{"award-number":["SERB Act 2008"]}],"id":[{"id":"10.13039\/501100001843","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001843","name":"Science and Engineering Research Board","doi-asserted-by":"publisher","award":["CRG\/2021\/005402"],"award-info":[{"award-number":["CRG\/2021\/005402"]}],"id":[{"id":"10.13039\/501100001843","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001843","name":"Science and Engineering Research Board","doi-asserted-by":"publisher","award":["2021-14161"],"award-info":[{"award-number":["2021-14161"]}],"id":[{"id":"10.13039\/501100001843","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001409","name":"Department of Science and Technology (DST)","doi-asserted-by":"publisher","award":["SERB Act 2008"],"award-info":[{"award-number":["SERB Act 2008"]}],"id":[{"id":"10.13039\/501100001409","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001409","name":"Department of Science and Technology (DST)","doi-asserted-by":"publisher","award":["CRG\/2021\/005402"],"award-info":[{"award-number":["CRG\/2021\/005402"]}],"id":[{"id":"10.13039\/501100001409","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001409","name":"Department of Science and Technology (DST)","doi-asserted-by":"publisher","award":["2021-14161"],"award-info":[{"award-number":["2021-14161"]}],"id":[{"id":"10.13039\/501100001409","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Indian Council of Medical Research","award":["SERB Act 2008"],"award-info":[{"award-number":["SERB Act 2008"]}]},{"name":"Indian Council of Medical Research","award":["CRG\/2021\/005402"],"award-info":[{"award-number":["CRG\/2021\/005402"]}]},{"name":"Indian Council of Medical Research","award":["2021-14161"],"award-info":[{"award-number":["2021-14161"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pharmaceutics"],"abstract":"<jats:p>Arthritis is the inflammation and tenderness of the joints because of some metabolic, infectious, or constitutional reasons. Existing arthritis treatments help in controlling the arthritic flares, but more advancement is required to cure arthritis meticulously. Biomimetic nanomedicine represents an exceptional biocompatible treatment to cure arthritis by minimizing the toxic effect and eliminating the boundaries of current therapeutics. Various intracellular and extracellular pathways can be targeted by mimicking the surface, shape, or movement of the biological system to form a bioinspired or biomimetic drug delivery system. Different cell-membrane-coated biomimetic systems, and extracellular-vesicle-based and platelets-based biomimetic systems represent an emerging and efficient class of therapeutics to treat arthritis. The cell membrane from various cells such as RBC, platelets, macrophage cells, and NK cells is isolated and utilized to mimic the biological environment. Extracellular vesicles isolated from arthritis patients can be used as diagnostic tools, and plasma or MSCs-derived extracellular vesicles can be used as a therapeutic target for arthritis. Biomimetic systems guide the nanomedicines to the targeted site by hiding them from the surveillance of the immune system. Nanomedicines can be functionalized using targeted ligand and stimuli-responsive systems to reinforce their efficacy and minimize off-target effects. This review expounds on various biomimetic systems and their functionalization for the therapeutic targets of arthritis treatment, and discusses the challenges for the clinical translation of the biomimetic system.<\/jats:p>","DOI":"10.3390\/pharmaceutics15041150","type":"journal-article","created":{"date-parts":[[2023,4,5]],"date-time":"2023-04-05T05:42:44Z","timestamp":1680673364000},"page":"1150","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["A Bird\u2019s Eye View of Various Cell-Based Biomimetic Nanomedicines for the Treatment of Arthritis"],"prefix":"10.3390","volume":"15","author":[{"given":"Nupur","family":"Vasdev","sequence":"first","affiliation":[{"name":"National Institute of Pharmaceutical Education and Research (NIPER), Ahmedabad, Department of Pharmaceuticals, Ministry of Chemicals and Fertilizers, Opposite Air Force Station, Palaj, Gandhinagar 382355, Gujarat, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bhakti","family":"Pawar","sequence":"additional","affiliation":[{"name":"National Institute of Pharmaceutical Education and Research (NIPER), Ahmedabad, Department of Pharmaceuticals, Ministry of Chemicals and Fertilizers, Opposite Air Force Station, Palaj, Gandhinagar 382355, Gujarat, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tanisha","family":"Gupta","sequence":"additional","affiliation":[{"name":"National Institute of Pharmaceutical Education and Research (NIPER), Ahmedabad, Department of Pharmaceuticals, Ministry of Chemicals and Fertilizers, Opposite Air Force Station, Palaj, Gandhinagar 382355, Gujarat, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahi","family":"Mhatre","sequence":"additional","affiliation":[{"name":"National Institute of Pharmaceutical Education and Research (NIPER), Ahmedabad, Department of Pharmaceuticals, Ministry of Chemicals and Fertilizers, Opposite Air Force Station, Palaj, Gandhinagar 382355, Gujarat, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3024-3148","authenticated-orcid":false,"given":"Rakesh Kumar","family":"Tekade","sequence":"additional","affiliation":[{"name":"National Institute of Pharmaceutical Education and Research (NIPER), Ahmedabad, Department of Pharmaceuticals, Ministry of Chemicals and Fertilizers, Opposite Air Force Station, Palaj, Gandhinagar 382355, Gujarat, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,4,5]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.mcna.2019.10.007","article-title":"Osteoarthritis: Pathology, Diagnosis, and Treatment Options","volume":"104","author":"Abramoff","year":"2020","journal-title":"Med. Clin. N. Am."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"j3248","DOI":"10.1136\/bmj.j3248","article-title":"Diagnosis and early management of inflammatory arthritis","volume":"358","author":"Ledingham","year":"2017","journal-title":"BMJ"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1016\/S0140-6736(20)30800-X","article-title":"Psoriatic arthritis: Still room for improvement","volume":"395","author":"Hetland","year":"2020","journal-title":"Lancet"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"2104640","DOI":"10.1002\/adfm.202104640","article-title":"Biomimetic and Bioinspired Intervention Strategies for the Treatment of Rheumatoid Arthritis","volume":"31","author":"Han","year":"2021","journal-title":"Adv. Funct. Mater."},{"key":"ref_5","doi-asserted-by":"crossref","unstructured":"Tang, C.-H. (2019). Research of Pathogenesis and Novel Therapeutics in Arthritis. Int. J. Mol. Sci., 20.","DOI":"10.3390\/ijms20071646"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"2315","DOI":"10.1016\/j.drudis.2021.04.026","article-title":"Integrated nanomaterials for non-invasive photothermal therapy of rheumatoid arthritis","volume":"26","author":"Gadeval","year":"2021","journal-title":"Drug Discov. Today"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.jcis.2019.02.073","article-title":"Nanogold-core multifunctional dendrimer for pulsatile chemo-, photothermal- and photodynamic- therapy of rheumatoid arthritis","volume":"544","author":"Pandey","year":"2019","journal-title":"J. Colloid Interface Sci."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1007\/s00296-020-04731-0","article-title":"The global prevalence of rheumatoid arthritis: A meta-analysis based on a systematic review","volume":"41","author":"Almutairi","year":"2021","journal-title":"Rheumatol. Int."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.joca.2021.04.020","article-title":"Epidemiology of osteoarthritis","volume":"30","author":"Allen","year":"2022","journal-title":"Osteoarthr. Cartil."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1016\/j.apsb.2021.03.013","article-title":"Nanomedicines for the treatment of rheumatoid arthritis: State of art and potential therapeutic strategies","volume":"11","author":"Wang","year":"2021","journal-title":"Acta Pharm. Sin. B"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1080\/17425247.2017.1372746","article-title":"Advanced nanomedicine for rheumatoid arthritis treatment: Focus on active targeting","volume":"14","author":"Chen","year":"2017","journal-title":"Expert Opin. Drug Deliv."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1715","DOI":"10.1093\/rheumatology\/kez286","article-title":"Nanomedicine: An emerging era of theranostics and therapeutics for rheumatoid arthritis","volume":"58","author":"Qamar","year":"2019","journal-title":"Rheumatology"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"5943","DOI":"10.1021\/acsnano.1c11132","article-title":"Biomimetic Nanomedicine-Triggered in Situ Vaccination for Innate and Adaptive Immunity Activations for Bacterial Osteomyelitis Treatment","volume":"16","author":"Lin","year":"2022","journal-title":"ACS Nano"},{"key":"ref_14","doi-asserted-by":"crossref","unstructured":"Singh, E., Osmani, R.A.M., Banerjee, R., Abu Lila, A.S., Moin, A., Almansour, K., Arab, H.H., Alotaibi, H.F., and Khafagy, E.-S. (2022). Poly \u03b5-Caprolactone Nanoparticles for Sustained Intra-Articular Immune Modulation in Adjuvant-Induced Arthritis Rodent Model. Pharmaceutics, 14.","DOI":"10.3390\/pharmaceutics14030519"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"12913","DOI":"10.1039\/C5RA22672D","article-title":"Intra-articular delivery of a methotrexate loaded nanostructured lipid carrier based smart gel for effective treatment of rheumatic diseases","volume":"6","author":"Shinde","year":"2016","journal-title":"RSC Adv."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1016\/j.jsps.2015.02.020","article-title":"Microsponges based novel drug delivery system for augmented arthritis therapy","volume":"23","author":"Osmani","year":"2015","journal-title":"Saudi Pharm. J."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.jconrel.2018.08.033","article-title":"Bioinspired and biomimetic systems for advanced drug and gene delivery","volume":"287","author":"Sabu","year":"2018","journal-title":"J. Control. Release"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1080\/10717544.2021.1938757","article-title":"Cell-derived biomimetic nanocarriers for targeted cancer therapy: Cell membranes and extracellular vesicles","volume":"28","author":"Li","year":"2021","journal-title":"Drug Deliv."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.apsb.2017.12.002","article-title":"Biomimetic nanoparticles for inflammation targeting","volume":"8","author":"Jin","year":"2017","journal-title":"Acta Pharm. Sin. B"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1080\/17425247.2022.2094364","article-title":"Recent progress in therapeutic strategies and biomimetic nanomedicines for rheumatoid arthritis treatment","volume":"19","author":"Li","year":"2022","journal-title":"Expert Opin. Drug Deliv."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.tips.2015.02.001","article-title":"Novel therapeutic targets in rheumatoid arthritis","volume":"36","author":"Koenders","year":"2015","journal-title":"Trends Pharmacol. Sci."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"686155","DOI":"10.3389\/fimmu.2021.686155","article-title":"Promising Therapeutic Targets for Treatment of Rheumatoid Arthritis","volume":"12","author":"Huang","year":"2021","journal-title":"Front. Immunol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1097\/BOR.0b013e32834518a3","article-title":"Pathophysiology of rheumatoid arthritis","volume":"23","author":"Cooles","year":"2011","journal-title":"Curr. Opin. Rheumatol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"101358","DOI":"10.1016\/j.nantod.2021.101358","article-title":"Rheumatoid arthritis microenvironment insights into treatment effect of nanomaterials","volume":"42","author":"Zhu","year":"2022","journal-title":"Nano Today"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.bioactmat.2021.06.006","article-title":"Reactive oxygen species-based nanomaterials for the treatment of myocardial ischemia reperfusion injuries","volume":"7","author":"Zhao","year":"2022","journal-title":"Bioact. Mater."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1038\/s41413-018-0016-9","article-title":"Rheumatoid arthritis: Pathological mechanisms and modern pharmacologic therapies","volume":"6","author":"Guo","year":"2018","journal-title":"Bone Res."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"92","DOI":"10.2174\/1871523011107020092","article-title":"Current and Future Therapeutic Targets of Rheumatoid Arthritis","volume":"10","author":"Zhou","year":"2011","journal-title":"Anti-Inflamm. Anti-Allergy Agents Med. Chem."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"246","DOI":"10.2174\/157339708786263915","article-title":"Update on Targets of Biologic Therapies for Rheumatoid Arthritis","volume":"4","author":"Rasheed","year":"2008","journal-title":"Curr. Rheumatol. Rev."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"20059","DOI":"10.1074\/jbc.R700016200","article-title":"JAK-STAT Signaling: From Interferons to Cytokines","volume":"282","author":"Schindler","year":"2007","journal-title":"J. Biol. Chem."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1038\/nri1226","article-title":"Regulation of JAK\u2013STAT signalling in the immune system","volume":"3","author":"Shuai","year":"2003","journal-title":"Nat. Rev. Immunol."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1186\/gb-2004-5-12-253","article-title":"The Janus kinases (Jaks)","volume":"5","author":"Yamaoka","year":"2004","journal-title":"Genome Biol."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1007\/s00281-017-0623-3","article-title":"Future therapeutic targets in rheumatoid arthritis?","volume":"39","author":"Cheung","year":"2017","journal-title":"Semin. Immunopathol."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"245","DOI":"10.2174\/1874312901206010245","article-title":"The Therapeutic Potential for PI3K Inhibitors in Autoimmune Rheumatic Diseases","volume":"6","author":"Clatworthy","year":"2012","journal-title":"Open Rheumatol. J."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1126\/science.296.5573.1655","article-title":"The Phosphoinositide 3-Kinase Pathway","volume":"296","author":"Cantley","year":"2002","journal-title":"Science"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"108793","DOI":"10.1016\/j.clim.2021.108793","article-title":"Recent advances on signaling pathways and their inhibitors in rheumatoid arthritis","volume":"230","author":"Liu","year":"2021","journal-title":"Clin. Immunol."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.autrev.2009.08.003","article-title":"The Wnt signaling pathway and rheumatoid arthritis","volume":"9","author":"Rabelo","year":"2010","journal-title":"Autoimmun. Rev."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s13317-020-00135-z","article-title":"NF-\u03baB signaling in rheumatoid arthritis with focus on fibroblast-like synoviocytes","volume":"11","author":"Farhadi","year":"2020","journal-title":"Autoimmun. Highlights"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1038\/s41392-023-01331-9","article-title":"Signaling pathways in rheumatoid arthritis: Implications for targeted therapy","volume":"8","author":"Ding","year":"2023","journal-title":"Signal Transduct. Target."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"5245","DOI":"10.4049\/jimmunol.178.8.5245","article-title":"Granulocyte-Macrophage Colony-Stimulating Factor (CSF) and Macrophage CSF-Dependent Macrophage Phenotypes Display Differences in Cytokine Profiles and Transcription Factor Activities: Implications for CSF Blockade in Inflammation1","volume":"178","author":"Fleetwood","year":"2007","journal-title":"J. Immunol."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"R170","DOI":"10.1186\/ar2079","article-title":"MLN51 and GM-CSF involvement in the proliferation of fibroblast-like synoviocytes in the pathogenesis of rheumatoid arthritis","volume":"8","author":"Jang","year":"2006","journal-title":"Arthritis Res. Ther."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1038\/nature07781","article-title":"Innate immune recognition of infected apoptotic cells directs TH17 cell differentiation","volume":"458","author":"Torchinsky","year":"2009","journal-title":"Nature"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.mtchem.2019.06.001","article-title":"Biomimetic nanostructures\/cues as drug delivery systems: A review","volume":"13","author":"Rasheed","year":"2019","journal-title":"Mater. Today Chem."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1016\/j.jconrel.2020.09.012","article-title":"Cell membrane coated nanocarriers-an efficient biomimetic platform for targeted therapy","volume":"327","author":"Dash","year":"2020","journal-title":"J. Control. Release"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1517\/17425247.2012.720969","article-title":"Antibodies against polyethylene glycol in healthy subjects and in patients treated with PEG-conjugated agents","volume":"9","author":"Garay","year":"2012","journal-title":"Expert Opin. Drug Deliv."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"27406","DOI":"10.1039\/D1RA05021D","article-title":"Recent progress of biomimetic motions\u2014From microscopic micro\/nanomotors to macroscopic actuators and soft robotics","volume":"11","author":"Zeng","year":"2021","journal-title":"RSC Adv."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1109\/TRO.2020.3033705","article-title":"Implementing rat-like motion for a small-sized biomimetic robot based on extraction of key movement joints","volume":"37","author":"Shi","year":"2020","journal-title":"IEEE Trans. Robot."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1038\/nnano.2007.149","article-title":"Bacteria-mediated delivery of nanoparticles and cargo into cells","volume":"2","author":"Akin","year":"2007","journal-title":"Nat. Nanotechnol."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"121551","DOI":"10.1016\/j.ijpharm.2022.121551","article-title":"Micro\/nanorobots for precise drug delivery via targeted transport and triggered release: A review","volume":"616","author":"Xu","year":"2022","journal-title":"Int. J. Pharm."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"256","DOI":"10.7150\/thno.22764","article-title":"Multimodal theranostic nanoformulations permit magnetic resonance bioimaging of antiretroviral drug particle tissue-cell biodistribution","volume":"8","author":"Kevadiya","year":"2018","journal-title":"Theranostics"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"7357","DOI":"10.1021\/acs.nanolett.6b02577","article-title":"The effect of cage shape on nanoparticle-based drug carriers: Anticancer drug release and efficacy via receptor blockade using dextran-coated iron oxide nanocages","volume":"16","author":"Rampersaud","year":"2016","journal-title":"Nano Lett."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"4294","DOI":"10.1002\/adma.201400303","article-title":"Colloidal RBC-Shaped, Hydrophilic, and Hollow Mesoporous Carbon Nanocapsules for Highly Efficient Biomedical Engineering","volume":"26","author":"Chen","year":"2014","journal-title":"Adv. Mater."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.actbio.2020.05.026","article-title":"Self-assembling prodrug nanotherapeutics for synergistic tumor targeted drug delivery","volume":"111","author":"Wang","year":"2020","journal-title":"Acta Biomater."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"128752","DOI":"10.1016\/j.snb.2020.128752","article-title":"Self-folded microrobot for active drug delivery and rapid ultrasound-triggered drug release","volume":"324","author":"Darmawan","year":"2020","journal-title":"Sens. Actuators B Chem."},{"key":"ref_54","doi-asserted-by":"crossref","unstructured":"Singh, A.K., Yadav, T.P., Pandey, B., Gupta, V., and Singh, S.P. (2019). Engineering nanomaterials for smart drug release: Recent advances and challenges. Appl. Target. Nano Drugs Deliv. Syst., 411\u2013449.","DOI":"10.1016\/B978-0-12-814029-1.00015-6"},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"119929","DOI":"10.1016\/j.biomaterials.2020.119929","article-title":"Layered self-assemblies for controlled drug delivery: A translational overview","volume":"242","author":"Sarode","year":"2020","journal-title":"Biomaterials"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.addr.2017.07.019","article-title":"The role of mucus in cell-based models used to screen mucosal drug delivery","volume":"124","author":"Lechanteur","year":"2018","journal-title":"Adv. Drug Deliv. Rev."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"120033","DOI":"10.1016\/j.carbpol.2022.120033","article-title":"Advances in the development of cyclodextrin-based nanogels\/microgels for biomedical applications: Drug delivery and beyond","volume":"297","author":"Topuz","year":"2022","journal-title":"Carbohydr. Polym."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"17080","DOI":"10.1021\/acsnano.1c03800","article-title":"Cell membrane-coated mimics: A methodological approach for fabrication, characterization for therapeutic applications, and challenges for clinical translation","volume":"15","author":"Chugh","year":"2021","journal-title":"ACS Nano"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1016\/j.bbamem.2014.01.006","article-title":"The basic structure and dynamics of cell membranes: An update of the Singer\u2013Nicolson model","volume":"1838","year":"2014","journal-title":"Biochim. Biophys. Acta (BBA)-Biomembr."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1021\/acsnano.6b06477","article-title":"Nanoparticles coated with neutrophil membranes can effectively treat cancer metastasis","volume":"11","author":"Kang","year":"2017","journal-title":"ACS Nano"},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"1903301","DOI":"10.1002\/advs.201903301","article-title":"Artificial mini dendritic cells boost T cell\u2013based immunotherapy for ovarian cancer","volume":"7","author":"Cheng","year":"2020","journal-title":"Adv. Sci."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1038\/nbt.3330","article-title":"Principles of nanoparticle design for overcoming biological barriers to drug delivery","volume":"33","author":"Blanco","year":"2015","journal-title":"Nat. Biotechnol."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.addr.2015.09.012","article-title":"PEGylation as a strategy for improving nanoparticle-based drug and gene delivery","volume":"99","author":"Suk","year":"2016","journal-title":"Adv. Drug Deliv. Rev."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"10980","DOI":"10.1073\/pnas.1106634108","article-title":"Erythrocyte membrane-camouflaged polymeric nanoparticles as a biomimetic delivery platform","volume":"108","author":"Hu","year":"2011","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"2939","DOI":"10.1039\/D0BM00015A","article-title":"Delivery of dual miRNA through CD44-targeted mesoporous silica nanoparticles for enhanced and effective triple-negative breast cancer therapy","volume":"8","author":"Ahir","year":"2020","journal-title":"Biomater. Sci."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1021\/acsnano.1c07556","article-title":"Biomimetic Hybrid Membrane-Coated Xuetongsu Assisted with Laser Irradiation for Efficient Rheumatoid Arthritis Therapy","volume":"16","author":"Yu","year":"2022","journal-title":"ACS Nano"},{"key":"ref_67","doi-asserted-by":"crossref","unstructured":"Li, J., Li, S., Li, C., Li, H., Liu, C., Zhang, P., Gong, P., and Cai, L. (2020). T cell\/Macrophage Dual-Targeting Biomimetic Triptolide Self-Assembly Nanodrugs for Rheumatoid Arthritis Therapy by Inflammatory Microenvironment Remodeling. ChemRxiv.","DOI":"10.26434\/chemrxiv.11894904.v1"},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/j.jconrel.2020.01.054","article-title":"TRAIL-expressing cell membrane nanovesicles as an anti-inflammatory platform for rheumatoid arthritis therapy","volume":"320","author":"Shi","year":"2020","journal-title":"J. Control. Release"},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1021\/acs.nanolett.8b03439","article-title":"Route to rheumatoid arthritis by macrophage-derived microvesicle-coated nanoparticles","volume":"19","author":"Li","year":"2018","journal-title":"Nano Lett."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1038\/s41565-018-0254-4","article-title":"Neutrophil membrane-coated nanoparticles inhibit synovial inflammation and alleviate joint damage in inflammatory arthritis","volume":"13","author":"Zhang","year":"2018","journal-title":"Nat. Nanotechnol."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"2101349","DOI":"10.1002\/adhm.202101349","article-title":"White blood cell membrane-coated nanoparticles: Recent development and medical applications","volume":"11","author":"Wang","year":"2022","journal-title":"Adv. Healthc. Mater."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"109855","DOI":"10.1016\/j.compositesb.2022.109855","article-title":"Neutrophil-erythrocyte hybrid membrane-coated hollow copper sulfide nanoparticles for targeted and photothermal\/anti-inflammatory therapy of osteoarthritis","volume":"237","author":"Xue","year":"2022","journal-title":"Compos. Part B Eng."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1038\/aps.2017.12","article-title":"Engineering exosomes as refined biological nanoplatforms for drug delivery","volume":"38","author":"Luan","year":"2017","journal-title":"Acta Pharmacol. Sin."},{"key":"ref_74","doi-asserted-by":"crossref","unstructured":"Cosenza, S., Ruiz, M., Maumus, M., Jorgensen, C., and No\u00ebl, D. (2017). Pathogenic or Therapeutic Extracellular Vesicles in Rheumatic Diseases: Role of Mesenchymal Stem Cell-Derived Vesicles. Int. J. Mol. Sci., 18.","DOI":"10.3390\/ijms18040889"},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1146\/annurev-cellbio-101512-122326","article-title":"Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles","volume":"30","author":"Colombo","year":"2014","journal-title":"Annu. Rev. Cell Dev. Biol."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1021\/acs.biochem.0c00631","article-title":"Effect of Surface Modification with Hydrocarbyl Groups on the Exocytosis of Nanoparticles","volume":"60","author":"Ho","year":"2021","journal-title":"Biochemistry"},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"461773","DOI":"10.1016\/j.chroma.2020.461773","article-title":"Modern isolation and separation techniques for extracellular vesicles","volume":"1636","author":"Liangsupree","year":"2021","journal-title":"J. Chromatogr. A"},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"207","DOI":"10.7150\/thno.62708","article-title":"Harnessing Tissue-derived Extracellular Vesicles for Osteoarthritis Theranostics","volume":"12","author":"Yin","year":"2022","journal-title":"Theranostics"},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"2428915","DOI":"10.1155\/2016\/2428915","article-title":"Extracellular Vesicles and Autophagy in Osteoarthritis","volume":"2016","author":"Gao","year":"2016","journal-title":"BioMed Res. Int."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1007\/s00223-018-0494-1","article-title":"Basic Calcium Phosphate Crystals Induce Osteoarthritis-Associated Changes in Phenotype Markers in Primary Human Chondrocytes by a Calcium\/Calmodulin Kinase 2-Dependent Mechanism","volume":"104","author":"Rong","year":"2019","journal-title":"Calcif. Tissue Int."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1186\/s13075-016-1178-8","article-title":"Extracellular vesicles in the pathogenesis of rheumatoid arthritis and osteoarthritis","volume":"18","author":"Withrow","year":"2016","journal-title":"Arthritis Res."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"2857","DOI":"10.1002\/art.10587","article-title":"Cell-derived microparticles in synovial fluid from inflamed arthritic joints support coagulation exclusively via a factor VII-dependent mechanism","volume":"46","author":"Berckmans","year":"2002","journal-title":"Arthritis Rheum."},{"key":"ref_83","first-page":"R536-544","article-title":"Synovial microparticles from arthritic patients modulate chemokine and cytokine release by synoviocytes","volume":"7","author":"Berckmans","year":"2005","journal-title":"Arthritis Res."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"3809","DOI":"10.1002\/art.22276","article-title":"Association of citrullinated proteins with synovial exosomes","volume":"54","author":"Skriner","year":"2006","journal-title":"Arthritis Rheum."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"7385","DOI":"10.4049\/jimmunol.176.12.7385","article-title":"A membrane form of TNF-alpha presented by exosomes delays T cell activation-induced cell death","volume":"176","author":"Zhang","year":"2006","journal-title":"J. Immunol."},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1186\/s12951-020-00675-6","article-title":"Exosome-based biomimetic nanoparticles targeted to inflamed joints for enhanced treatment of rheumatoid arthritis","volume":"18","author":"Yan","year":"2020","journal-title":"J. Nanobiotechnol."},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"6440","DOI":"10.4049\/jimmunol.174.10.6440","article-title":"Exosomes derived from IL-10-treated dendritic cells can suppress inflammation and collagen-induced arthritis","volume":"174","author":"Kim","year":"2005","journal-title":"J. Immunol."},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.biomaterials.2017.11.028","article-title":"MSC exosomes mediate cartilage repair by enhancing proliferation, attenuating apoptosis and modulating immune reactivity","volume":"156","author":"Zhang","year":"2018","journal-title":"Biomaterials"},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"e2213373119","DOI":"10.1073\/pnas.2213373119","article-title":"Photoacoustic image-guided biomimetic nanoparticles targeting rheumatoid arthritis","volume":"119","author":"Chen","year":"2022","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1186\/s12951-022-01447-0","article-title":"Microvesicle-camouflaged biomimetic nanoparticles encapsulating a metal-organic framework for targeted rheumatoid arthritis therapy","volume":"20","author":"Wang","year":"2022","journal-title":"J. Nanobiotechnol."},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/s12951-023-01773-x","article-title":"Peptide-anchored neutrophil membrane-coated biomimetic nanodrug for targeted treatment of rheumatoid arthritis","volume":"21","author":"Yang","year":"2023","journal-title":"J. Nanobiotechnol."},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.jconrel.2021.11.019","article-title":"M2-type exosomes nanoparticles for rheumatoid arthritis therapy via macrophage re-polarization","volume":"341","author":"Li","year":"2022","journal-title":"J. Control. Release Off. J. Control. Release Soc."},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"5036","DOI":"10.1021\/acsnano.9b01710","article-title":"Secreted Protein Acidic and Rich in Cysteine Mediated Biomimetic Delivery of Methotrexate by Albumin-Based Nanomedicines for Rheumatoid Arthritis Therapy","volume":"13","author":"Liu","year":"2019","journal-title":"ACS Nano"},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.biomaterials.2019.02.006","article-title":"MSC exosomes alleviate temporomandibular joint osteoarthritis by attenuating inflammation and restoring matrix homeostasis","volume":"200","author":"Zhang","year":"2019","journal-title":"Biomaterials"},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"eabe0083","DOI":"10.1126\/sciadv.abe0083","article-title":"Metabolically engineered stem cell-derived exosomes to regulate macrophage heterogeneity in rheumatoid arthritis","volume":"7","author":"You","year":"2021","journal-title":"Sci. Adv."},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1080\/1061186X.2022.2077949","article-title":"ZIF-8 nanoparticles coated with macrophage-derived microvesicles for sustained, targeted delivery of dexamethasone to arthritic joints","volume":"30","author":"Wang","year":"2022","journal-title":"J. Drug Target."},{"key":"ref_97","doi-asserted-by":"crossref","unstructured":"Tram\u015b, E., Malesa, K., Pomianowski, S., and Kami\u0144ski, R. (2022). Role of Platelets in Osteoarthritis-Updated Systematic Review and Meta-Analysis on the Role of Platelet-Rich Plasma in Osteoarthritis. Cells, 11.","DOI":"10.3390\/cells11071080"},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1038\/s41584-019-0187-9","article-title":"Platelets: Emerging facilitators of cellular crosstalk in rheumatoid arthritis","volume":"15","author":"Page","year":"2019","journal-title":"Nat. Rev. Rheumatol."},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"1901","DOI":"10.1021\/acs.accounts.8b00202","article-title":"Cell-Like Micromotors","volume":"51","author":"Gao","year":"2018","journal-title":"Acc. Chem. Res."},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.copbio.2018.11.010","article-title":"Platelet for drug delivery","volume":"58","author":"Lu","year":"2019","journal-title":"Curr. Opin. Biotechnol."},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ejpb.2022.01.004","article-title":"Biomimetic platelet membrane-coated nanoparticles for targeted therapy","volume":"172","author":"Han","year":"2022","journal-title":"Eur. J. Pharm. Biopharm. Off. J. Arb. Pharm. Verfahr."},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"2677","DOI":"10.2217\/nnm-2017-0225","article-title":"Cell membrane coated nanoparticles: Next-generation therapeutics","volume":"12","author":"Narain","year":"2017","journal-title":"Nanomedicine"},{"key":"ref_103","doi-asserted-by":"crossref","first-page":"6086","DOI":"10.1007\/s12274-018-2126-5","article-title":"Drug targeting through platelet membrane-coated nanoparticles for the treatment of rheumatoid arthritis","volume":"11","author":"He","year":"2018","journal-title":"Nano Res."},{"key":"ref_104","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1038\/nature15373","article-title":"Nanoparticle biointerfacing by platelet membrane cloaking","volume":"526","author":"Hu","year":"2015","journal-title":"Nature"},{"key":"ref_105","doi-asserted-by":"crossref","unstructured":"Noh, I. (2018). Biomimetic Medical Materials: From Nanotechnology to 3D Bioprinting, Springer.","DOI":"10.1007\/978-981-13-0445-3"},{"key":"ref_106","doi-asserted-by":"crossref","first-page":"4431","DOI":"10.2147\/IJN.S200284","article-title":"Cell membrane camouflaged nanoparticles: A new biomimetic platform for cancer photothermal therapy","volume":"14","author":"Wu","year":"2019","journal-title":"Int. J. Nanomed."},{"key":"ref_107","doi-asserted-by":"crossref","first-page":"3262","DOI":"10.1021\/acsnano.7b00376","article-title":"Unveiling the in Vivo Protein Corona of Circulating Leukocyte-like Carriers","volume":"11","author":"Corbo","year":"2017","journal-title":"ACS Nano"},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"863","DOI":"10.7150\/thno.11852","article-title":"Cell or cell membrane-based drug delivery systems","volume":"5","author":"Tan","year":"2015","journal-title":"Theranostics"},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1016\/j.drudis.2016.06.005","article-title":"Biofunctionalized nanoparticles: An emerging drug delivery platform for various disease treatments","volume":"21","author":"Bose","year":"2016","journal-title":"Drug Discov. Today"},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1080\/1042819042000201989","article-title":"Role of CD47 in Erythroid Cells and in Autoimmunity","volume":"45","author":"Oldenborg","year":"2004","journal-title":"Leuk. Lymphoma"},{"key":"ref_111","doi-asserted-by":"crossref","first-page":"6225","DOI":"10.1002\/smll.201502388","article-title":"Red Blood Cell Membrane as a Biomimetic Nanocoating for Prolonged Circulation Time and Reduced Accelerated Blood Clearance","volume":"11","author":"Rao","year":"2015","journal-title":"Small"},{"key":"ref_112","doi-asserted-by":"crossref","first-page":"2181","DOI":"10.1021\/nl500618u","article-title":"Cancer Cell Membrane-Coated Nanoparticles for Anticancer Vaccination and Drug Delivery","volume":"14","author":"Fang","year":"2014","journal-title":"Nano Lett."},{"key":"ref_113","doi-asserted-by":"crossref","first-page":"6981","DOI":"10.1039\/C5NR07588B","article-title":"Monocyte cell membrane-derived nanoghosts for targeted cancer therapy","volume":"8","author":"Krishnamurthy","year":"2016","journal-title":"Nanoscale"},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"9806","DOI":"10.1039\/C5NR02470F","article-title":"Erythrocyte membrane-coated NIR-triggered biomimetic nanovectors with programmed delivery for photodynamic therapy of cancer","volume":"7","author":"Ding","year":"2015","journal-title":"Nanoscale"},{"key":"ref_115","doi-asserted-by":"crossref","first-page":"4975","DOI":"10.1021\/nn501040h","article-title":"Core\u2013Shell Supramolecular Gelatin Nanoparticles for Adaptive and \u201cOn-Demand\u201d Antibiotic Delivery","volume":"8","author":"Li","year":"2014","journal-title":"ACS Nano"},{"key":"ref_116","doi-asserted-by":"crossref","first-page":"8884","DOI":"10.1039\/c3nr03064d","article-title":"Lipid-insertion enables targeting functionalization of erythrocyte membrane-cloaked nanoparticles","volume":"5","author":"Fang","year":"2013","journal-title":"Nanoscale 5"},{"key":"ref_117","doi-asserted-by":"crossref","unstructured":"Noh, I. (2018). Biomimetic Medical Materials: From Nanotechnology to 3D Bioprinting, Springer.","DOI":"10.1007\/978-981-13-0445-3"},{"key":"ref_118","doi-asserted-by":"crossref","first-page":"1901","DOI":"10.1021\/acs.accounts.8b00202","article-title":"Cell-like micromotors","volume":"51","author":"Gao","year":"2018","journal-title":"Acc. Chem. Res."},{"key":"ref_119","doi-asserted-by":"crossref","first-page":"102511","DOI":"10.1016\/j.autrev.2020.102511","article-title":"Exosomes: Effectual players in rheumatoid arthritis","volume":"19","author":"Tavasolian","year":"2020","journal-title":"Autoimmun. Rev."},{"key":"ref_120","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1021\/acsami.0c19468","article-title":"Treatment of Rheumatoid Arthritis by Serum Albumin Nanoparticles Coated with Mannose to Target Neutrophils","volume":"13","author":"Lyu","year":"2021","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"ref_121","first-page":"167","article-title":"Programmable materials and the nature of the DNA bond","volume":"347","author":"Jones","year":"2020","journal-title":"Spherical Nucleic Acids"},{"key":"ref_122","doi-asserted-by":"crossref","first-page":"2001669","DOI":"10.1002\/advs.202001669","article-title":"DNA Nanostructures and DNA-Functionalized Nanoparticles for Cancer Theranostics","volume":"7","author":"Nicolson","year":"2020","journal-title":"Adv. Sci."},{"key":"ref_123","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1038\/mt.2008.99","article-title":"Bone-protective Effects of Nonviral Gene Therapy With Folate\u2013Chitosan DNA Nanoparticle Containing Interleukin-1 Receptor Antagonist Gene in Rats With Adjuvant-induced Arthritis","volume":"16","author":"Fernandes","year":"2008","journal-title":"Mol. Ther."},{"key":"ref_124","doi-asserted-by":"crossref","first-page":"1803549","DOI":"10.1002\/adma.201803549","article-title":"Hyaluronic Acid\u2013Based Activatable Nanomaterials for Stimuli-Responsive Imaging and Therapeutics: Beyond CD44-Mediated Drug Delivery","volume":"31","author":"Choi","year":"2019","journal-title":"Adv. Mater."},{"key":"ref_125","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1080\/21691401.2018.1460373","article-title":"Recent approaches for targeted drug delivery in rheumatoid arthritis diagnosis and treatment","volume":"46","author":"Varshosaz","year":"2018","journal-title":"Artif. Cells Nanomed. Biotechnol."},{"key":"ref_126","doi-asserted-by":"crossref","first-page":"2167","DOI":"10.1016\/S0142-9612(01)00349-0","article-title":"Characterization of biodegradable drug delivery vehicles with the adhesive properties of leukocytes","volume":"23","author":"Eniola","year":"2002","journal-title":"Biomaterials"},{"key":"ref_127","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1021\/acs.molpharmaceut.0c00295","article-title":"Nanomedicine for the Treatment of Rheumatoid Arthritis","volume":"18","author":"Jeong","year":"2021","journal-title":"Mol. Pharm."},{"key":"ref_128","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1186\/ar327","article-title":"Suppression of murine collagen-induced arthritis by targeted apoptosis of synovial neovasculature","volume":"3","author":"Gerlag","year":"2001","journal-title":"Arthritis Res. Ther."},{"key":"ref_129","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1016\/j.addr.2006.09.020","article-title":"Thermo- and pH-responsive polymers in drug delivery","volume":"58","author":"Schmaljohann","year":"2006","journal-title":"Adv. Drug Deliv. Rev."},{"key":"ref_130","doi-asserted-by":"crossref","first-page":"1803717","DOI":"10.1002\/adma.201803717","article-title":"Effective and Targeted Human Orthotopic Glioblastoma Xenograft Therapy via a Multifunctional Biomimetic Nanomedicine","volume":"30","author":"Zou","year":"2018","journal-title":"Adv. Mater."},{"key":"ref_131","doi-asserted-by":"crossref","first-page":"1901541","DOI":"10.1002\/adhm.201901541","article-title":"Recent Advances in Nanotheranostics for Treat-to-Target of Rheumatoid Arthritis","volume":"9","author":"Wang","year":"2020","journal-title":"Adv. Healthc. Mater."},{"key":"ref_132","doi-asserted-by":"crossref","first-page":"121874","DOI":"10.1016\/j.ijpharm.2022.121874","article-title":"Development of pH-sensitive dextran-based methotrexate nanodrug for rheumatoid arthritis therapy through inhibition of JAK-STAT pathways","volume":"622","author":"Wang","year":"2022","journal-title":"Int. J. Pharm."},{"key":"ref_133","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.jconrel.2011.01.030","article-title":"Glutathione-responsive nano-vehicles as a promising platform for targeted intracellular drug and gene delivery","volume":"152","author":"Cheng","year":"2011","journal-title":"J. Control. Release"},{"key":"ref_134","doi-asserted-by":"crossref","first-page":"40288","DOI":"10.1039\/C8RA07574C","article-title":"Cancer cell membrane-modified biodegradable mesoporous silica nanocarriers for berberine therapy of liver cancer","volume":"8","author":"Yue","year":"2018","journal-title":"RSC Adv."},{"key":"ref_135","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1007\/s41048-020-00117-8","article-title":"Stimuli-responsive polymeric nanomaterials for rheumatoid arthritis therapy","volume":"6","author":"Xie","year":"2020","journal-title":"Biophys. Rep."},{"key":"ref_136","doi-asserted-by":"crossref","first-page":"3229","DOI":"10.1021\/acsbiomaterials.1c00412","article-title":"Glutathione Reductase-Sensitive Polymeric Micelles for Controlled Drug Delivery on Arthritic Diseases","volume":"7","author":"Lima","year":"2021","journal-title":"ACS Biomater. Sci. Eng."},{"key":"ref_137","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1021\/acs.accounts.7b00549","article-title":"Nanosystems Based on Magnetic Nanoparticles and Thermo- or pH-Responsive Polymers: An Update and Future Perspectives","volume":"51","author":"Mai","year":"2018","journal-title":"Acc. Chem. Res."},{"key":"ref_138","doi-asserted-by":"crossref","first-page":"1704800","DOI":"10.1002\/adma.201704800","article-title":"Biomimetic Platelet-Camouflaged Nanorobots for Binding and Isolation of Biological Threats","volume":"30","author":"Li","year":"2018","journal-title":"Adv. Mater."},{"key":"ref_139","doi-asserted-by":"crossref","first-page":"3881","DOI":"10.1002\/adfm.201501050","article-title":"Cell-Membrane-Coated Synthetic Nanomotors for Effective Biodetoxification","volume":"25","author":"Wu","year":"2015","journal-title":"Adv. Funct. Mater."},{"key":"ref_140","doi-asserted-by":"crossref","first-page":"4581","DOI":"10.1039\/C9TB00978G","article-title":"Ultrasound-triggered perfluorocarbon-derived nanobombs for targeted therapies of rheumatoid arthritis","volume":"7","author":"Zhu","year":"2019","journal-title":"J. Mater. Chem. B"},{"key":"ref_141","doi-asserted-by":"crossref","first-page":"1630","DOI":"10.1021\/acsnano.7b08219","article-title":"Light-Activatable Red Blood Cell Membrane-Camouflaged Dimeric Prodrug Nanoparticles for Synergistic Photodynamic\/Chemotherapy","volume":"12","author":"Pei","year":"2018","journal-title":"ACS Nano"},{"key":"ref_142","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.biomaterials.2018.01.007","article-title":"NIR-responsive cancer cytomembrane-cloaked carrier-free nanosystems for highly efficient and self-targeted tumor drug delivery","volume":"159","author":"Zhang","year":"2018","journal-title":"Biomaterials"},{"key":"ref_143","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/j.colsurfb.2015.04.048","article-title":"Temperature-responsive polymeric nanospheres containing methotrexate and gold nanoparticles: A multi-drug system for theranostic in rheumatoid arthritis","volume":"133","author":"Reis","year":"2015","journal-title":"Colloids Surf. B Biointerfaces"},{"key":"ref_144","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.biomaterials.2015.05.018","article-title":"Drug-loaded gold\/iron\/gold plasmonic nanoparticles for magnetic targeted chemo-photothermal treatment of rheumatoid arthritis","volume":"61","author":"Kim","year":"2015","journal-title":"Biomaterials"},{"key":"ref_145","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1080\/1061186X.2022.2053539","article-title":"A pH-Driven indomethacin-loaded nanomedicine for effective rheumatoid arthritis therapy by combining with photothermal therapy","volume":"30","author":"Hu","year":"2022","journal-title":"J. Drug Target."},{"key":"ref_146","doi-asserted-by":"crossref","first-page":"2347","DOI":"10.1016\/j.cclet.2021.03.015","article-title":"Challenges in cell membrane-camouflaged drug delivery systems: Development strategies and future prospects","volume":"32","author":"Liu","year":"2021","journal-title":"Chin. Chem. Lett."},{"key":"ref_147","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1038\/s41569-018-0110-0","article-title":"Platelet biology and functions: New concepts and clinical perspectives","volume":"16","author":"Heemskerk","year":"2019","journal-title":"Nat. Rev. Cardiol."},{"key":"ref_148","doi-asserted-by":"crossref","first-page":"8231","DOI":"10.1039\/C4TB00980K","article-title":"Structural elucidation of cell membrane-derived nanoparticles using molecular probes","volume":"2","author":"Fan","year":"2014","journal-title":"J. Mater. Chem. B"},{"key":"ref_149","doi-asserted-by":"crossref","first-page":"11476","DOI":"10.1021\/acs.chemrev.7b00194","article-title":"Form Follows Function: Nanoparticle Shape and Its Implications for Nanomedicine","volume":"117","author":"Kinnear","year":"2017","journal-title":"Chem. Rev."},{"key":"ref_150","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.ejpb.2022.06.014","article-title":"Biomimetic nanotherapeutics: Employing nanoghosts to fight melanoma","volume":"177","author":"Bagasariya","year":"2022","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"ref_151","doi-asserted-by":"crossref","first-page":"2002081","DOI":"10.1002\/adhm.202002081","article-title":"Recent Advances in Cell Membrane-Derived Biomimetic Nanotechnology for Cancer Immunotherapy","volume":"10","author":"Raza","year":"2021","journal-title":"Adv. Healthc. Mater."},{"key":"ref_152","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1039\/C9BM01392J","article-title":"Cell membrane biomimetic nanoparticles for inflammation and cancer targeting in drug delivery","volume":"8","author":"Wang","year":"2020","journal-title":"Biomater. Sci."},{"key":"ref_153","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.jconrel.2016.11.018","article-title":"Quality by design (QbD) approach of pharmacogenomics in drug designing and formulation development for optimization of drug delivery systems","volume":"245","author":"Gupta","year":"2017","journal-title":"J. Control. Release"},{"key":"ref_154","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1080\/03639045.2020.1821055","article-title":"Bridging the gap: Academia, industry and FDA convergence for nanomaterials","volume":"46","author":"Shah","year":"2020","journal-title":"Drug Dev. Ind. Pharm."}],"container-title":["Pharmaceutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1999-4923\/15\/4\/1150\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T19:10:23Z","timestamp":1760123423000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1999-4923\/15\/4\/1150"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,5]]},"references-count":154,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2023,4]]}},"alternative-id":["pharmaceutics15041150"],"URL":"https:\/\/doi.org\/10.3390\/pharmaceutics15041150","relation":{},"ISSN":["1999-4923"],"issn-type":[{"value":"1999-4923","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,5]]}}}