{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T21:39:35Z","timestamp":1792273175811,"version":"4.4.0"},"reference-count":275,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2024,10,30]],"date-time":"2024-10-30T00:00:00Z","timestamp":1730246400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Datta Meghe College of Pharmacy, Datta Meghe Institute of Higher Education and Research (Deemed to be University), Sawangi (M), Wardha, India"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pharmaceutics"],"abstract":"<jats:p>Microneedle technology revolutionizes ocular drug delivery by addressing challenges in treating ocular diseases. This review explores its potential impact, recent advancements, and clinical uses. This minimally invasive technique offers precise control of drug delivery to the eye, with various microneedle types showing the potential to penetrate barriers in the cornea and sclera, ensuring effective drug delivery. Recent advancements have improved safety and efficacy, offering sustained and controlled drug delivery for conditions like age-related macular degeneration and glaucoma. While promising, challenges such as regulatory barriers and long-term biocompatibility persist. Overcoming these through interdisciplinary research is crucial. Ultimately, microneedle drug delivery presents a revolutionary method with the potential to significantly enhance ocular disease treatment, marking a new era in eye care.<\/jats:p>","DOI":"10.3390\/pharmaceutics16111398","type":"journal-article","created":{"date-parts":[[2024,10,30]],"date-time":"2024-10-30T12:25:39Z","timestamp":1730291139000},"page":"1398","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["Revolutionizing Eye Care: Exploring the Potential of Microneedle Drug Delivery"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3301-5941","authenticated-orcid":false,"given":"Satish","family":"Rojekar","sequence":"first","affiliation":[{"name":"Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Swapnali","family":"Parit","sequence":"additional","affiliation":[{"name":"Institute of Chemical Technology, Marathwada Campus, Jalna 431203, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4145-4060","authenticated-orcid":false,"given":"Amol D.","family":"Gholap","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics, St. John Institute of Pharmacy and Research, Palghar 401404, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajit","family":"Manchare","sequence":"additional","affiliation":[{"name":"Institute of Chemical Technology, Marathwada Campus, Jalna 431203, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6513-3336","authenticated-orcid":false,"given":"Sopan N.","family":"Nangare","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics, H. 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