{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T19:33:12Z","timestamp":1776454392780,"version":"3.51.2"},"reference-count":14,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2018,5,22]],"date-time":"2018-05-22T00:00:00Z","timestamp":1526947200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pharmacy"],"abstract":"<jats:p>Appointment-based medication synchronization (ABMS) programs have been associated with increased adherence and persistence to chronic medications. Adherence to statin therapy, angiotensin-converting enzyme inhibitors (ACEIs), angiotensin receptor blockers (ARBs), and non-insulin antidiabetic medications (NIDM) are used to determine a health plan\u2019s Centers for Medicare and Medicaid Services (CMS) Star Rating under a pay-for-performance model. The objective of this study was to evaluate the impact of implementing an ABMS program on overall pharmacy adherence measures for statins, ACEI\/ARBs, and NIDM, as presented through the Electronic Quality Improvement Platform for Plans and Pharmacies (EQuIPP\u00a9) platform. This retrospective, pre-post ABMS program study evaluated EQuIPP\u00a9 generated adherence performance measures, represented as proportion of days covered (PDC), 6-months before and 6- and 12-months after the ABMS service for statin therapy, ACEIs\/ARBs, and NIDM. All adherence measures showed statistically significant improvement in PDC percentage post ABMS implementation, except for NIDM percentage in 6-months post-ABMS service. This study shows that a comprehensive medication synchronization program can enhance adherence measures that are important to health plans to increase CMS Star Rating under a pay-for-performance model.<\/jats:p>","DOI":"10.3390\/pharmacy6020044","type":"journal-article","created":{"date-parts":[[2018,5,22]],"date-time":"2018-05-22T04:34:03Z","timestamp":1526963643000},"page":"44","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Impact of Appointment-Based Medication Synchronization on Proportion of Days Covered for Chronic Medications"],"prefix":"10.3390","volume":"6","author":[{"given":"Nancy","family":"Dao","sequence":"first","affiliation":[{"name":"Western University of Health Sciences College of Pharmacy, Pomona, CA 91766, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sun","family":"Lee","sequence":"additional","affiliation":[{"name":"Western University of Health Sciences College of Pharmacy, Pomona, CA 91766, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Micah","family":"Hata","sequence":"additional","affiliation":[{"name":"Western University of Health Sciences College of Pharmacy, Pomona, CA 91766, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lord","family":"Sarino","sequence":"additional","affiliation":[{"name":"Ralphs Grocery Company, Compton, CA 92620, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2018,5,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Academy of Managed Care Pharmacy, American Pharmacists Association (2014). Medicare star ratings: Stakeholder proceedings on community pharmacy and managed care partnerships in quality. J. Am. Pharm. Assoc. (2003), 54, 228\u2013240.","DOI":"10.1331\/JAPhA.2014.13180"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1016\/j.ahj.2007.12.011","article-title":"Medication nonadherence is associated with a broad range of adverse outcomes in patients with coronary artery disease","volume":"155","author":"Ho","year":"2008","journal-title":"Am. Heart J."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1097\/01.mlr.0000163641.86870.af","article-title":"Impact of medication adherence on hospitalization risk and healthcare cost","volume":"43","author":"Sokol","year":"2005","journal-title":"Med. Care"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1377\/hlthaff.2011.0931","article-title":"An integrated pharmacy-based program improved medication prescription and adherence rates in diabetes patients","volume":"31","author":"Brennan","year":"2012","journal-title":"Health Aff. (Millwood)"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1331\/JAPhA.2013.13082","article-title":"Adherence and persistence associated with an appointment-based medication synchronization program","volume":"53","author":"Holdford","year":"2013","journal-title":"J. Am. Pharm. Assoc. (2003)"},{"key":"ref_6","unstructured":"World Health Organization (2003). Adherence to Long-Term Therapies: Evidence for Action, National Academies Press."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/j.japh.2017.05.016","article-title":"The impact of a retail prescription synchronization program on medication adherence","volume":"57","author":"Girdish","year":"2017","journal-title":"J. Am. Pharm. Assoc. (2003)"},{"key":"ref_8","unstructured":"American Pharmacists Association Foundation (2017, August 10). Pharmacy\u2019s Appointment Based Model a Prescription Synchronization Program that Improves Adherence. Available online: http:\/\/www.aphafoundation.org\/sites\/default\/files\/ckeditor\/files\/ABMWhitePaper-FINAL-20130923(3).pdf."},{"key":"ref_9","first-page":"662","article-title":"Impact of Appointment-Based Medication Synchronization on Existing Users of Chronic Medications","volume":"21","author":"Holdford","year":"2015","journal-title":"J. Manag. Care Spec. Pharm."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.japh.2016.11.008","article-title":"The impact of medication synchronization on quality care criteria in an independent community pharmacy","volume":"57","author":"Hinson","year":"2017","journal-title":"J. Am. Pharm. Assoc. (2003)"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1331\/JAPhA.2015.14242","article-title":"Participant satisfaction with a community-based medication synchronization program","volume":"55","author":"Butler","year":"2015","journal-title":"J. Am. Pharm. Assoc. (2003)"},{"key":"ref_12","unstructured":"(2017, August 15). EQuIPP\u00a9 Website. Available online: http:\/\/www.EQuIPP.org."},{"key":"ref_13","unstructured":"Centers for Medicare and Medicaid Services (2018, May 01). Trends in Part C & D Star Rating Measure Cut Points, Available online: https:\/\/www.cms.gov\/Medicare\/Prescription-Drug-Coverage\/PrescriptionDrugCovGenIn\/Downloads\/2016-Trends-in-Part-C-and-D-Star-Ratings-Cut-Points.pdf."},{"key":"ref_14","first-page":"787","article-title":"Is There a Relationship between Part D Medication Adherence and Part C Intermediate Outcomes Star Ratings Measures?","volume":"22","author":"Ta","year":"2016","journal-title":"J. Manag. Care Spec. Pharm."}],"container-title":["Pharmacy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2226-4787\/6\/2\/44\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T15:05:18Z","timestamp":1760195118000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2226-4787\/6\/2\/44"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5,22]]},"references-count":14,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2018,6]]}},"alternative-id":["pharmacy6020044"],"URL":"https:\/\/doi.org\/10.3390\/pharmacy6020044","relation":{},"ISSN":["2226-4787"],"issn-type":[{"value":"2226-4787","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,5,22]]}}}