{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T05:01:57Z","timestamp":1787029317188,"version":"build-2736575974"},"reference-count":53,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2021,8,20]],"date-time":"2021-08-20T00:00:00Z","timestamp":1629417600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100009051","name":"Universidad T\u00e9cnica Federico Santa Mar\u00eda","doi-asserted-by":"publisher","award":["DGIIE"],"award-info":[{"award-number":["DGIIE"]}],"id":[{"id":"10.13039\/100009051","id-type":"DOI","asserted-by":"publisher"}]},{"name":"LabSun","award":["I+Di"],"award-info":[{"award-number":["I+Di"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Plants"],"abstract":"<jats:p>Gray mold disease, which is caused by Botrytis cinerea Pers ex. Fr., results in serious economic losses to Lycopersicum esculentum (tomato) crop productivity. In this study, we explored the possibility that mixtures of essential oils (EOs) and their respective hydrolates (HYSs) could be used to control this disease. Thus, EOs and HYSs were obtained from Origanum vulgare, Thymus vulgaris, Citrus limon, and Citrus sinensis by hydrodistillation. In vitro antifungal activities were evaluated, and EC50 values of 15.9 and 19.8 \u00b5g\/mL were obtained for EOs of thyme and oregano, respectively. These activities are due mainly to volatile compounds, thymol and carvacrol. Results from in vivo assays show that although most tomatoes were infested five days after inoculation, the damage was considerably reduced by the application of an EO\/HYS mixture of thyme. The disease incidence indexes of B. cinerea tomato rot, percentage and severity, measured four days after inoculation, were reduced by 70% and 76%, respectively, as compared with the inoculum control. These results suggest that a combination of HYSs and EOs enhances antifungal activity, and that optimization of relative concentrations, volumes, and the nature of the compounds, could design a formulation able to control B. cinerea inoculum on tomato fruits.<\/jats:p>","DOI":"10.3390\/plants10081719","type":"journal-article","created":{"date-parts":[[2021,8,22]],"date-time":"2021-08-22T22:59:27Z","timestamp":1629673167000},"page":"1719","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":39,"title":["Assessing the Control of Postharvest Gray Mold Disease on Tomato Fruit Using Mixtures of Essential Oils and Their Respective Hydrolates"],"prefix":"10.3390","volume":"10","author":[{"given":"Conny","family":"Brito","sequence":"first","affiliation":[{"name":"Departamento de Ingenier\u00eda Qu\u00edmica y Ambiental, Universidad T\u00e9cnica Federico Santa Mar\u00eda, Avenida Espa\u00f1a 1680, Valpara\u00edso 2340000, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrik","family":"Hansen","sequence":"additional","affiliation":[{"name":"Departamento de Ingenier\u00eda Qu\u00edmica y Ambiental, Universidad T\u00e9cnica Federico Santa Mar\u00eda, Avenida Espa\u00f1a 1680, Valpara\u00edso 2340000, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4054-7487","authenticated-orcid":false,"given":"Luis","family":"Espinoza","sequence":"additional","affiliation":[{"name":"Departamento de Qu\u00edmica, Universidad T\u00e9cnica Federico Santa Mar\u00eda, Avenida Espa\u00f1a 1680, Valpara\u00edso 2340000, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mart\u00edn","family":"Fa\u00fandez","sequence":"additional","affiliation":[{"name":"Departamento de Qu\u00edmica, Universidad T\u00e9cnica Federico Santa Mar\u00eda, Avenida Espa\u00f1a 1680, Valpara\u00edso 2340000, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8007-6264","authenticated-orcid":false,"given":"Andr\u00e9s F.","family":"Olea","sequence":"additional","affiliation":[{"name":"Instituto de Ciencias Qu\u00edmicas Aplicadas, Facultad de Ingenier\u00eda, Universidad Aut\u00f3noma de Chile, El Llano Subercaseaux 2801, Santiago 8900000, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebasti\u00e1n","family":"Pino","sequence":"additional","affiliation":[{"name":"LABSUN (Laboratorio Sustentable Natural), Valpara\u00edso 2340000, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7345-1123","authenticated-orcid":false,"given":"Katy","family":"D\u00edaz","sequence":"additional","affiliation":[{"name":"Departamento de Qu\u00edmica, Universidad T\u00e9cnica Federico Santa Mar\u00eda, Avenida Espa\u00f1a 1680, Valpara\u00edso 2340000, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,8,20]]},"reference":[{"key":"ref_1","unstructured":"Jarvis, W. 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