{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T12:23:54Z","timestamp":1784118234665,"version":"3.55.0"},"reference-count":44,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2022,2,10]],"date-time":"2022-02-10T00:00:00Z","timestamp":1644451200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Plants"],"abstract":"<jats:p>This study reports the effects of sulfur (S) deprivation in cultures of Galdieria sulphuraria (Cyanidiophyceae). Galdieria is a unicellular red alga that usually grows, forming biomats on rocks, in S-rich environments. These are volcanic areas, where S is widespread since H2S is the prevalent form of gas. The glutathione content in Galdieria sulphuraria is much higher than that found in the green algae and even under conditions of S deprivation for 7 days, it remains high. On the other hand, the S deprivation causes a decrease in the total protein content and a significant increase in soluble protein fraction. This suggests that in the conditions of S starvation, the synthesis of enzymatic proteins, that metabolically support the cell in the condition of nutritional stress, could be up regulated. Among these enzymatic proteins, those involved in cell detoxification, due to the accumulation of ROS species, have been counted.<\/jats:p>","DOI":"10.3390\/plants11040481","type":"journal-article","created":{"date-parts":[[2022,2,11]],"date-time":"2022-02-11T02:35:51Z","timestamp":1644546951000},"page":"481","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Sulfur Starvation in Extremophilic Microalga Galdieria sulphuraria: Can Glutathione Contribute to Stress Tolerance?"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5791-2885","authenticated-orcid":false,"given":"Giovanna","family":"Salbitani","sequence":"first","affiliation":[{"name":"Dipartimento di Biologia, Universit\u00e0 di Napoli Federico II, Via Cinthia 21, 80126 Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Perrone","sequence":"additional","affiliation":[{"name":"Dipartimento di Biologia, Universit\u00e0 di Napoli Federico II, Via Cinthia 21, 80126 Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2472-0435","authenticated-orcid":false,"given":"Luigi","family":"Rosati","sequence":"additional","affiliation":[{"name":"Dipartimento di Biologia, Universit\u00e0 di Napoli Federico II, Via Cinthia 21, 80126 Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1647-3593","authenticated-orcid":false,"given":"Carmen","family":"Laezza","sequence":"additional","affiliation":[{"name":"Dipartimento di Agraria, Universit\u00e0 di Napoli Federico II, Portici, 80055 Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simona","family":"Carfagna","sequence":"additional","affiliation":[{"name":"Dipartimento di Biologia, Universit\u00e0 di Napoli Federico II, Via Cinthia 21, 80126 Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,2,10]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.1080\/14786419.2018.1425853","article-title":"Antioxidant and anti-proliferative properties of extracts from heterotrophic cultures of Galdieria sulphuraria","volume":"33","author":"Bottone","year":"2019","journal-title":"Nat. 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