{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T13:35:18Z","timestamp":1787578518710,"version":"build-2736575974"},"reference-count":104,"publisher":"MDPI AG","issue":"13","license":[{"start":{"date-parts":[[2022,6,25]],"date-time":"2022-06-25T00:00:00Z","timestamp":1656115200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Plants"],"abstract":"<jats:p>Caryocar coriaceum is an endemic tree of Brazil, occurring mainly in the northeast region in the Cerrado environment. The species, popularly known as \u201cpequi\u201d, produces fruits that are used in the manufacture of oil for food and medicinal purposes. This work reviewed studies conducted with the species, highlighting its ethnomedicinal use, its pharmacological potential, including its chemical constituents, and its cultural and socioeconomic importance. Information was obtained through the main scientific research platforms. The keyword \u201cCaryocar coriaceum\u201d was used as the main index for searching the following platforms: PubMed\u00ae, PubMed Central\u00ae, SciElo, Scopus\u00ae and Web of ScienceTM. The compiled papers demonstrate that C. coriaceum has great medicinal, economic and cultural importance for northeastern Brazil. Popularly, the fruits of C. coriaceum are used to treat broncho-pulmonary diseases (bronchitis, colds and flu). The fixed oil is widely used to relieve pain from various causes in the treatment of inflammation, flu, eczema, burns, fever, rickets, indigestion, heart murmurs, fatigue and erectile dysfunction. Some of these uses are corroborated by pharmacological trials, which have demonstrated the antioxidant, healing, anti-inflammatory, gastroprotective, antinociceptive and antimicrobial properties of the species. Chemically, fatty acids and phenolic compounds are the main constituents recorded for the species. Due to its medicinal properties, the fruits and oil of C. coriaceum have a high commercial demand and are one of the main forms of subsistence activities for local populations. On the other hand, the extractive practice of the fruits, associated with anthropic factors and its physiological nature, makes the species threatened with extinction. Thus, public management policies are highly necessary in order to avoid its extinction.<\/jats:p>","DOI":"10.3390\/plants11131685","type":"journal-article","created":{"date-parts":[[2022,6,26]],"date-time":"2022-06-26T21:01:41Z","timestamp":1656277301000},"page":"1685","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Caryocar coriaceum Wittm. (Caryocaraceae): Botany, Ethnomedicinal Uses, Biological Activities, Phytochemistry, Extractivism and Conservation Needs"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0966-9750","authenticated-orcid":false,"given":"Jos\u00e9 Weverton","family":"Almeida-Bezerra","sequence":"first","affiliation":[{"name":"Department of Botany, Federal University of Pernambuco\u2013UFPE, Recife 50670-901, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2081-8304","authenticated-orcid":false,"given":"Jos\u00e9 Jailson Lima","family":"Bezerra","sequence":"additional","affiliation":[{"name":"Department of Botany, Federal University of Pernambuco\u2013UFPE, Recife 50670-901, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0581-2609","authenticated-orcid":false,"given":"Viviane Bezerra da","family":"Silva","sequence":"additional","affiliation":[{"name":"Department of Botany, Federal University of Pernambuco\u2013UFPE, Recife 50670-901, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6634-4207","authenticated-orcid":false,"given":"Henrique Douglas Melo","family":"Coutinho","sequence":"additional","affiliation":[{"name":"Department of Biological Chemistry, Regional University of Cariri\u2013URCA, Crato 63105-000, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Galberto Martins da","family":"Costa","sequence":"additional","affiliation":[{"name":"Department of Biological Chemistry, Regional University of Cariri\u2013URCA, Crato 63105-000, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5934-5201","authenticated-orcid":false,"given":"Nat\u00e1lia","family":"Cruz-Martins","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal"},{"name":"Institute for Research and Innovation in Health (i3S), University of Porto, 4200-319 Porto, Portugal"},{"name":"Institute of Research and Advanced Training in Health Sciences and Technologies (CESPU), Rua Central de Gandra, 1317, 4585-116 Gandra PRD, Portugal"},{"name":"TOXRUN\u2014Toxicology Research Unit, University Institute of Health Sciences, CESPU, CRL, 4585-116 Gandra, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9938-0151","authenticated-orcid":false,"given":"Christophe","family":"Hano","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Eure et Loir Campus, University of Orleans, 28000 Chartres, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6657-585X","authenticated-orcid":false,"given":"Saulo Almeida de","family":"Menezes","sequence":"additional","affiliation":[{"name":"Biotechnology Center, Federal University of Rio Grande do Sul\u2013UFRGS, Porto Alegre 91501-970, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5898-1257","authenticated-orcid":false,"given":"Maria Flaviana Bezerra","family":"Morais-Braga","sequence":"additional","affiliation":[{"name":"Department of Biological Chemistry, Regional University of Cariri\u2013URCA, Crato 63105-000, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio Fernando Morais de","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Department of Botany, Federal University of Pernambuco\u2013UFPE, Recife 50670-901, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,6,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1590\/2175-7860201667527","article-title":"Flora das cangas da Serra dos Caraj\u00e1s, Par\u00e1, Brasil: Caryocaraceae","volume":"67","author":"Nunes","year":"2016","journal-title":"Rodrigu\u00e9sia"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"D507","DOI":"10.1051\/ocl\/2017040","article-title":"Pequi: A brazilian fruit with potential uses for the fat industry","volume":"24","author":"Guedes","year":"2017","journal-title":"OCL"},{"key":"ref_3","first-page":"335","article-title":"Rhizoboleae","volume":"12","author":"Wittmack","year":"1886","journal-title":"Fl. 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