{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T03:18:57Z","timestamp":1792293537690,"version":"4.4.0"},"reference-count":64,"publisher":"MDPI AG","issue":"16","license":[{"start":{"date-parts":[[2022,8,12]],"date-time":"2022-08-12T00:00:00Z","timestamp":1660262400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001321","name":"NRF","doi-asserted-by":"publisher","award":["UID 120980"],"award-info":[{"award-number":["UID 120980"]}],"id":[{"id":"10.13039\/501100001321","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001321","name":"NRF","doi-asserted-by":"publisher","award":["RDG D113"],"award-info":[{"award-number":["RDG D113"]}],"id":[{"id":"10.13039\/501100001321","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Sefako Makgatho Health Sciences University Research and Development","award":["UID 120980"],"award-info":[{"award-number":["UID 120980"]}]},{"name":"Sefako Makgatho Health Sciences University Research and Development","award":["RDG D113"],"award-info":[{"award-number":["RDG D113"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Plants"],"abstract":"<jats:p>Viscum continuum E. Mey. Ex Sprague is a woody evergreen semi-parasitic shrub that grows on the branches of other trees. It is used by African traditional healers for post-stroke management. This study reports on the qualitative phytochemical screening and the antioxidant and antimicrobial activities of Viscum continuum\u2019s acetone, methanol, hexane and dichloromethane extracts. Standard protocols for the phytochemical screening of extracts were employed. TLC bio-autography was used for qualitative antioxidants analysis. Assays: 2,2-diphenyl-1-picrylhydrazyl, H2O2 free-radical scavenging and ferric chloride reducing power were carried out for quantitative antioxidant analysis. The antimicrobial potential of extracts was screened using disc diffusion, bio-autography and broth micro-dilution. The results indicate the presence of alkaloids, phenolics and tannins in all extracts. Acetone and methanol revealed significant amount of saponins, phenolics, tannins and terpenoids. The extracts exhibited significant antioxidant potential on TLC with positive compound bands at an Rf range of 0.05\u20130.89. DPPH, H2O2 and the reduction of Fe3+ to Fe2+ assays indicated that methanol extract has a strong antioxidant potential, followed by acetone, DCM and lastly hexane. The extracts of Viscum continuum show the potential to be antibacterial agents. It can be concluded that Viscum continuum extracts contain phytochemicals which are capable of mitigating against chronic health conditions such as cancer, stroke and stress-related and infectious diseases.<\/jats:p>","DOI":"10.3390\/plants11162094","type":"journal-article","created":{"date-parts":[[2022,8,12]],"date-time":"2022-08-12T01:51:11Z","timestamp":1660269071000},"page":"2094","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Phytochemical Screening, Antioxidant and Antibacterial Properties of Extracts of Viscum continuum E. Mey. Ex Sprague, a South African Mistletoe"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5096-5367","authenticated-orcid":false,"given":"Sipho","family":"Mapfumari","sequence":"first","affiliation":[{"name":"Department of Pharmaceutical Sciences, School of Pharmacy, Sefako Makgatho Health Sciences University, P.O. Box 218, Pretoria 0208, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0938-0073","authenticated-orcid":false,"given":"Noel-David","family":"Nogbou","sequence":"additional","affiliation":[{"name":"Department of Microbiology, School of Medicine, Sefako Makgatho Health Sciences University, P.O Box 211, Pretoria 0208, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Musyoki","sequence":"additional","affiliation":[{"name":"Department of Microbiology, School of Medicine, Sefako Makgatho Health Sciences University, P.O Box 211, Pretoria 0208, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stanley","family":"Gololo","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, School of Science and Technology, Sefako Makgatho Health Sciences University, P.O Box 235, Pretoria 0208, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8613-2543","authenticated-orcid":false,"given":"Mmamosheledi","family":"Mothibe","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Faculty of Pharmacy, Rhodes University, P.O. Box 94, Grahams Town 6139, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8178-1221","authenticated-orcid":false,"given":"Kokoette","family":"Bassey","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, School of Pharmacy, Sefako Makgatho Health Sciences University, P.O. Box 218, Pretoria 0208, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,8,12]]},"reference":[{"key":"ref_1","first-page":"231","article-title":"Full Length Original Research Paper","volume":"6","author":"Tariq","year":"2014","journal-title":"Int. J. Drug Dev. Res."},{"key":"ref_2","first-page":"168","article-title":"Phytochemistry of Medicinal Plants","volume":"1","author":"Saxena","year":"2013","journal-title":"J. Pharmacogn. 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