{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T20:13:42Z","timestamp":1790712822019,"version":"4.1.0"},"reference-count":40,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2023,1,14]],"date-time":"2023-01-14T00:00:00Z","timestamp":1673654400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001807","name":"FAPESP","doi-asserted-by":"crossref","award":["2016\/10896-0"],"award-info":[{"award-number":["2016\/10896-0"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Plants"],"abstract":"<jats:p>Lipoxygenases (LOXs) are enzymes that catalyze the addition of an oxygen molecule to unsaturated fatty acids, thus forming hydroperoxides. In plants, these enzymes are encoded by a multigene family found in several organs with varying activity patterns, by which they are classified as LOX9 or LOX13. They are involved in several physiological functions, such as growth, fruit development, and plant defense. Despite several studies on genes of the LOX family in plants, most studies are restricted to a single species or a few closely related species. This study aimed to analyze the diversity, evolution, and expression of LOX genes in angiosperm species. We identified 247 LOX genes among 23 species of angiosperms and basal plants. Phylogenetic analyses identified clades supporting LOX13 and two main clades for LOX9: LOX9_A and LOX9_B. Eudicot species such as Tarenaya hassleriana, Capsella rubella, and Arabidopsis thaliana did not present LOX9_B genes; however, LOX9_B was present in all monocots used in this study. We identified that there were potential new subcellular localization patterns and conserved residues of oxidation for LOX9 and LOX13 yet unexplored. In summary, our study provides a basis for the further functional and evolutionary study of lipoxygenases in angiosperms.<\/jats:p>","DOI":"10.3390\/plants12020398","type":"journal-article","created":{"date-parts":[[2023,1,16]],"date-time":"2023-01-16T04:06:47Z","timestamp":1673842007000},"page":"398","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Genome-Wide Analysis of Lipoxygenase (LOX) Genes in Angiosperms"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5406-0661","authenticated-orcid":false,"given":"Paula","family":"Camargo","sequence":"first","affiliation":[{"name":"Group of Genomics and Transcriptomes in Plants, Department of Biodiversity, Institute of Biosciences, S\u00e3o Paulo State University, UNESP, Rio Claro 13506-900, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nat\u00e1lia","family":"Calzado","sequence":"additional","affiliation":[{"name":"Group of Genomics and Transcriptomes in Plants, Department of Biodiversity, Institute of Biosciences, S\u00e3o Paulo State University, UNESP, Rio Claro 13506-900, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilara","family":"Budzinski","sequence":"additional","affiliation":[{"name":"Group of Genomics and Transcriptomes in Plants, Department of Biodiversity, Institute of Biosciences, S\u00e3o Paulo State University, UNESP, Rio Claro 13506-900, SP, Brazil"},{"name":"Departamento de Gen\u00e9tica, Escola Superior de Agricultura \u201cLuiz de Queiroz\u201d, University of S\u00e3o Paulo, USP, Piracicaba 13418-900, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1290-0853","authenticated-orcid":false,"given":"Douglas","family":"Domingues","sequence":"additional","affiliation":[{"name":"Group of Genomics and Transcriptomes in Plants, Department of Biodiversity, Institute of Biosciences, S\u00e3o Paulo State University, UNESP, Rio Claro 13506-900, SP, Brazil"},{"name":"Departamento de Gen\u00e9tica, Escola Superior de Agricultura \u201cLuiz de Queiroz\u201d, University of S\u00e3o Paulo, USP, Piracicaba 13418-900, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,1,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1007\/s12374-020-09241-x","article-title":"Plant Lipoxygenases and their role in plant physiology","volume":"63","author":"Viswanath","year":"2020","journal-title":"J. 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