{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T23:38:49Z","timestamp":1788910729819,"version":"build-2803163510"},"reference-count":151,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2023,5,31]],"date-time":"2023-05-31T00:00:00Z","timestamp":1685491200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Romanian National Authority for Scientific Research and Innovation","award":["9N\/2019, PN 19110302"],"award-info":[{"award-number":["9N\/2019, PN 19110302"]}]},{"name":"Romanian National Authority for Scientific Research and Innovation","award":["PN 19070502"],"award-info":[{"award-number":["PN 19070502"]}]},{"name":"Romanian National Authority for Scientific Research and Innovation","award":["9N\/2019, PN 19110303"],"award-info":[{"award-number":["9N\/2019, PN 19110303"]}]},{"name":"Romanian National Authority for Scientific Research and Innovation","award":["19PFE\/30.12.2021"],"award-info":[{"award-number":["19PFE\/30.12.2021"]}]},{"name":"Romanian National Authority for Scientific Research and Innovation","award":["20N\/2023, PN 23150301"],"award-info":[{"award-number":["20N\/2023, PN 23150301"]}]},{"name":"Romanian National Authority for Scientific Research and Innovation","award":["12N\/2019"],"award-info":[{"award-number":["12N\/2019"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Plants"],"abstract":"<jats:p>In addition to the naturopathic medicines based on the antiseptic, anti-inflammatory, anticancer, or antioxidant properties of plant extracts that have been capitalized upon through the pharmaceutical industry, the increasing interest of the food industry in this area requires potent new materials capable of supporting this market. This study aimed to evaluate the in vitro amino acid contents and antioxidant activities of ethanolic extracts from sixteen plants. Our results show high accumulated amino acid contents, mainly of proline, glutamic, and aspartic acid. The most consistent values of essential amino acids were isolated from T. officinale, U. dioica, C. majus, A. annua, and M. spicata. The results of the 2,2-diphenyl-1-pycrylhydrazyl (DPPH) radical scavenging assay indicate that R. officinalis was the most potent antioxidant, followed by four other extracts (in decreasing order): T. serpyllum, C. monogyna, S. officinalis, and M. koenigii. The network and principal component analyses found four natural groupings between samples based on DPPH free radical scavenging activity content. Each plant extracts\u2019 antioxidant action was discussed based on similar results found in the literature, and a lower capacity was observed for most species. An overall ranking of the analyzed plant species can be accomplished due to the range of experimental methods. The literature review revealed that these natural antioxidants represent the best side-effect-free alternatives to synthetic additives, especially in the food processing industry.<\/jats:p>","DOI":"10.3390\/plants12112183","type":"journal-article","created":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T02:12:45Z","timestamp":1685585565000},"page":"2183","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Comparative Amino Acid Profile and Antioxidant Activity in Sixteen Plant Extracts from Transylvania, Romania"],"prefix":"10.3390","volume":"12","author":[{"given":"Andreea Maria","family":"Iordache","sequence":"first","affiliation":[{"name":"National Research and Development Institute for Cryogenics and Isotopic Technologies, 4 Uzinei Str., 240050 R\u00e2mnicu V\u00e2lcea, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4084-1950","authenticated-orcid":false,"given":"Constantin","family":"Nechita","sequence":"additional","affiliation":[{"name":"National Research and Development Institute for Forestry \u201cMarin Dracea\u201d Calea Bucovinei, 73 Bis, 725100 Campulung Moldovenesc, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula","family":"Podea","sequence":"additional","affiliation":[{"name":"Chemistry Department, Faculty of Chemistry and Chemical Engineering, Babe\u0219-Bolyai University, Arany Janos 11, 400028 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niculina Sonia","family":"\u0218uvar","sequence":"additional","affiliation":[{"name":"National Institute for Research and Development in Mine Safety and Protection to Explosion, 32-34 General Vasile Milea Str., 332047 Petro\u0219ani, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cornelia","family":"Mesaro\u1e63","sequence":"additional","affiliation":[{"name":"Department of Biophysics, Faculty of Pharmacy, George Emil Palade University of Medicine, Pharmacy, Science and Technology of T\u00e2rgu Mure\u0219, 38 Gh. Marinescu Str., 540139 T\u00e2rgu Mure\u015f, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cezara","family":"Voica","sequence":"additional","affiliation":[{"name":"National Institute for Research and Development of Isotopic and Molecular Technologies, 67-103 Donat Str., 400293 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramona","family":"Bleiziffer","sequence":"additional","affiliation":[{"name":"Biomolecular Physics Department, Faculty of Physics, Babe\u0219-Bolyai University, Kog\u0103lniceanu 1, 400084 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica","family":"Culea","sequence":"additional","affiliation":[{"name":"Biomolecular Physics Department, Faculty of Physics, Babe\u0219-Bolyai University, Kog\u0103lniceanu 1, 400084 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,5,31]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.joim.2021.07.003","article-title":"An overview of the anti-SARS-CoV-2 properties of Artemisia annua, its antiviral action, protein-associated mechanisms, and repurposing for COVID-19 treatment","volume":"19","author":"Fuzimoto","year":"2021","journal-title":"J. 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