{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T10:41:53Z","timestamp":1788691313629,"version":"build-2803163510"},"reference-count":82,"publisher":"MDPI AG","issue":"23","license":[{"start":{"date-parts":[[2023,11,24]],"date-time":"2023-11-24T00:00:00Z","timestamp":1700784000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Ministry of Science, Technology, and Innovation, MINCIENCIAS"},{"name":"call Ecosistema Cient\u00edfico-Colombia Cient\u00edfica"},{"name":"Francisco Jos\u00e9 de Caldas Fund"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Plants"],"abstract":"<jats:p>The Colombian Choc\u00f3 is known for its rich biodiversity and to harbor plant species that are under-explored, including the genus Sloanea. This study aimed to analyze the chemical composition of derivatized ethanolic extracts from S. chocoana and S. pittieriana using BSTFA and TMCS through GC\u2013MS, and to assess cell viability of immortalized human non-tumorigenic keratinocytes (HaCaT) and periodontal ligament fibroblast cells using crude extracts through MTS assay. Antioxidant and photoprotective properties were determined using DPPH assay and spectrophotometry. Antifungal activity of extracts against Candida species was developed following the CLSI standard M27, 4th ed. The sun protective factor (SPF) and UVA\/UVB ratio values were calculated using the Mansur equation and the Boots star rating system. The critical wavelength (\u03bbc) was determined by calculating the integrated optical density curve\u2019s area. The transmission of erythema and pigmentation was calculated through equations that use constants to calculate the flux of erythema and pigmentation. The GC\u2013MS analysis identified 37 compounds for S. chocoana and 38 for S. pittieriana, including alkaloids, triterpenoids, and polyphenolics, among others. Both extracts exhibited proliferative effects on periodontal ligament fibroblasts, did not affect the viability of HaCaT cells, and showed excellent antioxidant activities (46.1% and 43.7%). Relevant antifungal activity was observed with S. pittieriana extract against Candida albicans (GM\u2013MIC: 4 \u00b5g\/mL), followed by C. auris and C. glabrata (GM\u2013MIC: 32 \u00b5g\/mL), while S. chocoana extract was active against C. albicans and C. glabrata (GM\u2013MIC: 16 and 32 \u00b5g\/mL, respectively). High SPF values (31.0 and 30.0), \u03bbc (393.98 and 337.81 nm), UVA\/UVB ratio (1.5 and 1.2), and low percentage of transmission of erythema and pigmentation were determined for S. chocoana and S. pittieriana, respectively. Results showed that species of Sloanea constitute a promising alternative as ingredients for developing skincare products, and exhaustive studies are required for their sustainable uses.<\/jats:p>","DOI":"10.3390\/plants12233953","type":"journal-article","created":{"date-parts":[[2023,11,24]],"date-time":"2023-11-24T03:43:59Z","timestamp":1700797439000},"page":"3953","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Sloanea chocoana and S. pittieriana (Elaeocarpaceae): Chemical and Biological Studies of Ethanolic Extracts and Skincare Properties"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2469-6279","authenticated-orcid":false,"given":"Patricia","family":"Quintero-Rinc\u00f3n","sequence":"first","affiliation":[{"name":"Natural Products Group, Universidad Tecnol\u00f3gica del Choc\u00f3, Quibdo 270002, Colombia"},{"name":"Research Group Design and Formulation of Medicines, Cosmetics, and Related, Faculty of Pharmaceutical and Food Sciences, Universidad de Antioquia, Medellin 050010, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nayive","family":"Pino-Ben\u00edtez","sequence":"additional","affiliation":[{"name":"Natural Products Group, Universidad Tecnol\u00f3gica del Choc\u00f3, Quibdo 270002, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8801-6239","authenticated-orcid":false,"given":"Elkin","family":"Galeano","sequence":"additional","affiliation":[{"name":"Bioactive Substances Research Group, Faculty of Pharmaceutical and Food Sciences, Universidad de Antioquia, Medellin 050010, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cris","family":"Rojo-Uribe","sequence":"additional","affiliation":[{"name":"Dermatological Research Group, Faculty of Medicine, Universidad de Antioquia, Medellin 050010, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana C.","family":"Mesa-Arango","sequence":"additional","affiliation":[{"name":"Dermatological Research Group, Faculty of Medicine, Universidad de Antioquia, Medellin 050010, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oscar A.","family":"Fl\u00f3rez-Acosta","sequence":"additional","affiliation":[{"name":"Research Group Design and Formulation of Medicines, Cosmetics, and Related, Faculty of Pharmaceutical and Food Sciences, Universidad de Antioquia, Medellin 050010, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,11,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"131","DOI":"10.3897\/phytokeys.160.54993","article-title":"A new rare and endemic species of Sloanea (Elaeocarpaceae) from the Choc\u00f3 region of Ecuador","volume":"160","year":"2020","journal-title":"PhytoKeys"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"61","DOI":"10.3417\/2022628","article-title":"Sloanea pilosa (Elaeocarpaceae), a Rare and New Emergent Tree Species from the Ecuadorian Amazon","volume":"30","author":"Andino","year":"2022","journal-title":"Novon"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"257","DOI":"10.4067\/S0717-66432013000200007","article-title":"Revisi\u00f3n de la secci\u00f3n Brevispicae del g\u00e9nero Sloanea (Elaeocarpaceae) en Bolivia. 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