{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T05:07:03Z","timestamp":1792040823809,"version":"4.4.0"},"reference-count":131,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2023,12,27]],"date-time":"2023-12-27T00:00:00Z","timestamp":1703635200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Plants"],"abstract":"<jats:p>Daucus carota L., a member of the Apiaceae family, comprises 13 subspecies, with one being cultivated (D. carota L. ssp. sativus (Hoffm.) Arcang.) and the remaining being wild. Traditionally, the wild carrot has been recognized for its antilithic, diuretic, carminative, antiseptic, and anti-inflammatory properties and has been employed in the treatment of urinary calculus, cystitis, gout, prostatitis, and cancer. While extensive literature is available on the phytochemical, pharmacological, and therapeutic evaluations of the cultivated carrot, limited information has been published on the wild carrot. A thorough search was conducted on the phytochemical composition, folk-medicine uses, and pharmacological properties of wild carrot subspecies (Daucus carota L. ssp. carota). Various electronic databases were consulted, and the literature spanning from 1927 to early 2023 was reviewed. Thirteen wild Daucus carota subspecies were analyzed, revealing over 310 compounds, including terpenoids, phenylpropenoids, flavonoids, and phenolic acids, with 40 constituting more than 3% of the composition. This review also highlights the antioxidant, anticancer, antipyretic, analgesic, antibacterial, antifungal, hypolipidemic, and hepato- and gastroprotective properties of wild carrot subspecies. Existing in vitro and in vivo studies support their traditional uses in treating infections, inflammation, and cancer. However, further research on other subspecies is required to confirm additional applications. Well-designed preclinical and clinical trials are still necessary to establish the safety and efficacy of wild Daucus carota for human use.<\/jats:p>","DOI":"10.3390\/plants13010093","type":"journal-article","created":{"date-parts":[[2023,12,28]],"date-time":"2023-12-28T09:56:27Z","timestamp":1703757387000},"page":"93","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["The Wild Carrot (Daucus carota): A Phytochemical and Pharmacological Review"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8475-5683","authenticated-orcid":false,"given":"Jana","family":"Ismail","sequence":"first","affiliation":[{"name":"Pharmaceutical Sciences Department, School of Pharmacy, Lebanese American University, Byblos 1102-2801, Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9924-2496","authenticated-orcid":false,"given":"Wassim N.","family":"Shebaby","sequence":"additional","affiliation":[{"name":"Pharmaceutical Sciences Department, School of Pharmacy, Lebanese American University, Byblos 1102-2801, Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joey","family":"Daher","sequence":"additional","affiliation":[{"name":"Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, Byblos 1102-2801, Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joelle C.","family":"Boulos","sequence":"additional","affiliation":[{"name":"Institute of Pharmacy and Biomedical Sciences, Department of Pharmaceutical Biology, Johannes Gutenberg University, 55128 Mainz, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8033-6951","authenticated-orcid":false,"given":"Robin","family":"Taleb","sequence":"additional","affiliation":[{"name":"Department of Natural Sciences, School of Arts and Sciences, Lebanese American University, Byblos 1102-2801, Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8275-7263","authenticated-orcid":false,"given":"Costantine F.","family":"Daher","sequence":"additional","affiliation":[{"name":"Department of Natural Sciences, School of Arts and Sciences, Lebanese American University, Byblos 1102-2801, Lebanon"},{"name":"Alice Ramez Chagoury School of Nursing, Lebanese American University, Byblos 1102-2801, Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamad","family":"Mroueh","sequence":"additional","affiliation":[{"name":"Pharmaceutical Sciences Department, School of Pharmacy, Lebanese American University, Byblos 1102-2801, Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,12,27]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1080\/0972060X.2010.10643785","article-title":"Composition of the essential oil from Daucus carota ssp. carota growing wild in Vienna","volume":"13","author":"Chizzola","year":"2010","journal-title":"J. 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