{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T03:20:06Z","timestamp":1782789606630,"version":"3.54.5"},"reference-count":27,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2024,6,14]],"date-time":"2024-06-14T00:00:00Z","timestamp":1718323200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Ministry of Culture and Innovation of Hungary","award":["KDP-2021"],"award-info":[{"award-number":["KDP-2021"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Plants"],"abstract":"<jats:p>The goal of this study was to clarify the role of capsule size and morphology in the alkaloid yield of poppy. In 2023, two industrial varieties from large-scale cultivation were investigated. Three classes of capsule size (large, medium, and small) and four organelles (wall, placenta, disc, and thalamus) of the seedless capsule were studied for their mass proportions and alkaloid contents. In \u2018Meara\u2019, large capsules had 41% lower total alkaloid levels than smaller ones. In \u2018Morgana\u2019, there was no difference in total alkaloids between size groups, but large capsules had higher contents of codeine and thebaine. Among the four organelles, the wall represented the largest mass in both varieties (60\u201367%), while the disc and the thalamus gave the lowest proportions (below 9%). In the variety \u2019Meara\u2019, the highest alkaloid contents appeared in the wall (2.69% d.w.), followed by the placenta, and the other two parts. \u2018Morgana\u2019 accumulated the highest alkaloid content (3.72% d.w.) in the placenta. Morphine follows the trend of the total content, while codeine and thebaine may differ. Accurate information on the accumulation of alkaloids in the generative organs may contribute to increasing effectiveness in target-oriented breeding and optimization of cultivation with an appropriate choice of variety.<\/jats:p>","DOI":"10.3390\/plants13121640","type":"journal-article","created":{"date-parts":[[2024,6,14]],"date-time":"2024-06-14T03:52:53Z","timestamp":1718337173000},"page":"1640","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Alkaloid Accumulation and Distribution within the Capsules of Two Opium Poppy (Papaver somniferum L.) Varieties"],"prefix":"10.3390","volume":"13","author":[{"given":"P\u00e9ter","family":"M\u00e1jer","sequence":"first","affiliation":[{"name":"Department of Medicinal and Aromatic Plants, Institute of Horticultural Sciences, Hungarian University of Agriculture and Life Sciences, 1118 Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4359-0728","authenticated-orcid":false,"given":"\u00c9va Z\u00e1mborin\u00e9","family":"N\u00e9meth","sequence":"additional","affiliation":[{"name":"Department of Medicinal and Aromatic Plants, Institute of Horticultural Sciences, Hungarian University of Agriculture and Life Sciences, 1118 Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,6,14]]},"reference":[{"key":"ref_1","unstructured":"Salavert, A. (2010). Le Pavot (Papaver somniferum) \u00e0 la fin du 6 e Mill\u00e9naire av. J.-C. en Europe Occidentale, Anthropobotanica."},{"key":"ref_2","unstructured":"(2024, April 13). Available online: https:\/\/www.mordorintelligence.com\/industry-reports\/global-poppy-seed-market."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"423","DOI":"10.17221\/222\/2011-PSE","article-title":"Production of morphine and variability of significant characters of Papaver somniferum L","volume":"57","author":"Novak","year":"2011","journal-title":"Plant Soil Environ."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"3215","DOI":"10.2174\/092986709788803295","article-title":"Recent developments in the chemistry of thebaine and its transformation products as pharmacological targets","volume":"16","author":"Berenyi","year":"2009","journal-title":"Curr. Med. Chem."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1007\/s11119-020-09707-5","article-title":"Prediction of poppy thebaine alkaloid concentration using UAS remote sensing","volume":"21","author":"Iqbal","year":"2020","journal-title":"Precis. Agric."},{"key":"ref_6","first-page":"100290","article-title":"The influence of sowing and planting seedlings at different dates in autumn on the yield and quality of the opium poppy (Papaver somniferum L.)","volume":"21","author":"Kara","year":"2021","journal-title":"J. Appl. Res. Med. Aromat. Plants"},{"key":"ref_7","first-page":"333","article-title":"The influence of sowing date on yield and features of low morphine poppy (Papaver somniferum L.) cv. Mieszko","volume":"1","author":"Oleksy","year":"2010","journal-title":"Ro\u015bl. Oleiste"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1071\/AR9840253","article-title":"Losses, by leaching, of alkaloids from the capsule of the poppy (Papaver somniferum L.) during maturation","volume":"35","author":"Hofman","year":"1984","journal-title":"Aust. J. Agric. Res."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1017\/S0021859600044312","article-title":"The effect of delayed harvest and leaching on the morphine concentration of poppy (Papaver somniferum L.) capsules","volume":"104","author":"Laughlin","year":"1985","journal-title":"J. Agric. Sci."},{"key":"ref_10","unstructured":"Bern\u00e1th, J. (1999). Poppy: The Genus Papaver, CRC Press."},{"key":"ref_11","unstructured":"Fist, A.J. (2001, January 29\u201331). The Tasmanian poppy industry: A case study of the application of science and technology. Proceedings of the 10th Agronomy Conference \u2018Science and Technology: Delivering Results for Agriculture?\u2019, Hobart, Australia."},{"key":"ref_12","unstructured":"Svachula, V., Vach, M., and Tun, D. (2009). Poppy cultivars from the EU common catalogue-yields and alkaloids spectrum. Prosperous Oil Crops Prague, Bioenergy in Czech Republic."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.1016\/j.agwat.2010.05.011","article-title":"Water stress effects on growth, development and yield of opium poppy (Papaver somniferum L.)","volume":"97","author":"Kamkar","year":"2010","journal-title":"Agric. Water Manag."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"189","DOI":"10.17557\/tjfc.54263","article-title":"Evaluation of selected poppy (Papaver somniferum L.) cultivars: Industrial aspect","volume":"19","author":"Skalicky","year":"2014","journal-title":"Turk. J. Field Crops"},{"key":"ref_15","unstructured":"Cotterill, P. (2013). Method of Altering the Alkaloid Composition in Poppy Plants. (No 8,377,851), U.S. Patent."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1007\/s00217-007-0739-0","article-title":"Evaluation of selected poppy (Papaver somniferum L.) lines by their morphine and other alkaloids contents","volume":"226","author":"Arslan","year":"2008","journal-title":"Eur. Food Res. Technol."},{"key":"ref_17","first-page":"39","article-title":"The effect of autumn and spring sowing on yield, oil and morphine contents in the Turkish poppy (Papaver somniferum L.) cultivars","volume":"22","author":"Kara","year":"2017","journal-title":"Turk. J. Field Crops"},{"key":"ref_18","first-page":"101","article-title":"Breeding aspects of poppy in Slovakia","volume":"1036","year":"2011","journal-title":"Acta Hortic."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"484","DOI":"10.17221\/4062-PSE","article-title":"Split nitrogen doses and their efficiency in poppy (Papaver somniferum L.) nutrition","volume":"50","author":"Richter","year":"2004","journal-title":"Plant Soil Environ."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/0022-474X(80)90010-7","article-title":"Studies on the compositional changes in poppy capsule components during maturation and drying","volume":"16","author":"Nash","year":"1980","journal-title":"J. Stored Prod. Res."},{"key":"ref_21","first-page":"15","article-title":"Variation of dry substance and alkaloid accumulation in the developing capsule of poppy (Papaver somniferum L.)","volume":"28","year":"1989","journal-title":"Herba Hung."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1111\/j.1744-7348.2008.00289.x","article-title":"The latex capacity of opium poppy capsules is fixed early in capsule development and is not a major determinant in morphine yield","volume":"154","author":"Harvest","year":"2009","journal-title":"Ann. Appl. Bot."},{"key":"ref_23","first-page":"29","article-title":"Study of correlation system of variables in poppy cultivars by principal component analysis","volume":"28","year":"1989","journal-title":"Herba Hung."},{"key":"ref_24","unstructured":"(2024, April 18). UPOV Guidelines for the Conduct of Tests for Distinctness, Uniformity and Stability Opium\/Seed Poppy TG\/166\/4. Available online: https:\/\/www.upov.int\/edocs\/tgdocs\/en\/tg166.pdf."},{"key":"ref_25","first-page":"326","article-title":"Correlated response in opium poppy (Papaver somniferum L.)","volume":"17","author":"Singh","year":"1995","journal-title":"Curr. Res. Med. Arom. Plants"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1055\/s-0028-1101536","article-title":"The lacitiferous vessels of Papaver somniferum L","volume":"8","author":"Fairbairn","year":"1960","journal-title":"Planta Med."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"4110","DOI":"10.1105\/tpc.113.115113","article-title":"Morphine biosyntheis in opium poppy involves two cell types: Sieve elements and laticifers","volume":"25","author":"Onoyovwe","year":"2013","journal-title":"Plant Cell"}],"container-title":["Plants"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2223-7747\/13\/12\/1640\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T14:58:25Z","timestamp":1760108305000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2223-7747\/13\/12\/1640"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,14]]},"references-count":27,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2024,6]]}},"alternative-id":["plants13121640"],"URL":"https:\/\/doi.org\/10.3390\/plants13121640","relation":{},"ISSN":["2223-7747"],"issn-type":[{"value":"2223-7747","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,14]]}}}