{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T14:53:47Z","timestamp":1788188027082,"version":"build-2803163510"},"reference-count":169,"publisher":"MDPI AG","issue":"13","license":[{"start":{"date-parts":[[2024,7,3]],"date-time":"2024-07-03T00:00:00Z","timestamp":1719964800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006769","name":"Russian Science Foundation","doi-asserted-by":"publisher","award":["23-44-00006"],"award-info":[{"award-number":["23-44-00006"]}],"id":[{"id":"10.13039\/501100006769","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006769","name":"Russian Science Foundation","doi-asserted-by":"publisher","award":["MAUX2302"],"award-info":[{"award-number":["MAUX2302"]}],"id":[{"id":"10.13039\/501100006769","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Ministry of Business, Innovation and Employment (Wellington, NZ)","award":["23-44-00006"],"award-info":[{"award-number":["23-44-00006"]}]},{"name":"Ministry of Business, Innovation and Employment (Wellington, NZ)","award":["MAUX2302"],"award-info":[{"award-number":["MAUX2302"]}]},{"name":"Israel Chemicals Ltd. (ICL)","award":["23-44-00006"],"award-info":[{"award-number":["23-44-00006"]}]},{"name":"Israel Chemicals Ltd. (ICL)","award":["MAUX2302"],"award-info":[{"award-number":["MAUX2302"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Plants"],"abstract":"<jats:p>Phosphorus (P) is an important and irreplaceable macronutrient. It is central to energy and information storage and exchange in living cells. P is an element with a \u201cbroken geochemical cycle\u201d since it lacks abundant volatile compounds capable of closing the P cycle. P fertilizers are critical for global food security, but the reserves of minable P are scarce and non-evenly distributed between countries of the world. Accordingly, the risks of global crisis due to limited access to P reserves are expected to be graver than those entailed by competition for fossil hydrocarbons. Paradoxically, despite the scarcity and value of P reserves, its usage is extremely inefficient: the current waste rate reaches 80% giving rise to a plethora of unwanted consequences such as eutrophication leading to harmful algal blooms. Microalgal biotechnology is a promising solution to tackle this challenge. The proposed review briefly presents the relevant aspects of microalgal P metabolism such as cell P reserve composition and turnover, and the regulation of P uptake kinetics for maximization of P uptake efficiency with a focus on novel knowledge. The multifaceted role of polyPhosphates, the largest cell depot for P, is discussed with emphasis on the P toxicity mediated by short-chain polyPhosphates. Opportunities and hurdles of P bioremoval via P uptake from waste streams with microalgal cultures, either suspended or immobilized, are discussed. Possible avenues of P-rich microalgal biomass such as biofertilizer production or extraction of valuable polyPhosphates and other bioproducts are considered. The review concludes with a comprehensive assessment of the current potential of microalgal biotechnology for ensuring the sustainable usage of phosphorus.<\/jats:p>","DOI":"10.3390\/plants13131834","type":"journal-article","created":{"date-parts":[[2024,7,3]],"date-time":"2024-07-03T11:35:57Z","timestamp":1720006557000},"page":"1834","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Getting Grip on Phosphorus: Potential of Microalgae as a Vehicle for Sustainable Usage of This Macronutrient"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6746-8511","authenticated-orcid":false,"given":"Alexei","family":"Solovchenko","sequence":"first","affiliation":[{"name":"Department of Bioengineering, Faculty of Biology, Lomonosov Moscow State University, 1-12 Leninskie Gory, 119234 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maxence","family":"Plouviez","sequence":"additional","affiliation":[{"name":"The Cawthron Institute, Nelson 7010, New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8618-0687","authenticated-orcid":false,"given":"Inna","family":"Khozin-Goldberg","sequence":"additional","affiliation":[{"name":"Microalgal Biotechnology Laboratory, French Associates Institute for Agriculture and Biotechnology of Drylands, Ben-Gurion University of the Negev, Sde-Boqer Campus, Midreshet Ben-Gurion 8499000, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,7,3]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1104\/pp.89.4.1331","article-title":"31P-nuclear magnetic resonance determination of phosphate compartmentation in leaves of reproductive soybeans (Glycine max L.) as affected by phosphate nutrition","volume":"89","author":"Lauer","year":"1989","journal-title":"Plant Physiol."},{"key":"ref_2","first-page":"1","article-title":"Phosphorus: Back to the Roots","volume":"Volume 48","author":"Lambers","year":"2015","journal-title":"Annual Plant Reviews"},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"White, P.J., and Hammond, J.P. 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