{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T21:18:20Z","timestamp":1792617500840,"version":"4.5.0"},"reference-count":92,"publisher":"MDPI AG","issue":"16","license":[{"start":{"date-parts":[[2024,8,17]],"date-time":"2024-08-17T00:00:00Z","timestamp":1723852800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key R&amp;D Program of China","doi-asserted-by":"publisher","award":["2023YFE1304303"],"award-info":[{"award-number":["2023YFE1304303"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key R&amp;D Program of China","doi-asserted-by":"publisher","award":["2022SZX32"],"award-info":[{"award-number":["2022SZX32"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key R&amp;D Program of China","doi-asserted-by":"publisher","award":["1122014"],"award-info":[{"award-number":["1122014"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"name":"projects of Science &amp; Technology Specific Projects in Agricultural High-tech Industrial Demonstration Area of the Yellow River Delta","award":["2023YFE1304303"],"award-info":[{"award-number":["2023YFE1304303"]}]},{"name":"projects of Science &amp; Technology Specific Projects in Agricultural High-tech Industrial Demonstration Area of the Yellow River Delta","award":["2022SZX32"],"award-info":[{"award-number":["2022SZX32"]}]},{"name":"projects of Science &amp; Technology Specific Projects in Agricultural High-tech Industrial Demonstration Area of the Yellow River Delta","award":["1122014"],"award-info":[{"award-number":["1122014"]}]},{"name":"Start-up Foundation for High Talents of Qingdao Agricultural University","award":["2023YFE1304303"],"award-info":[{"award-number":["2023YFE1304303"]}]},{"name":"Start-up Foundation for High Talents of Qingdao Agricultural University","award":["2022SZX32"],"award-info":[{"award-number":["2022SZX32"]}]},{"name":"Start-up Foundation for High Talents of Qingdao Agricultural University","award":["1122014"],"award-info":[{"award-number":["1122014"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Plants"],"abstract":"<jats:p>Sorghum (Sorghum bicolor) holds a significant position as the fifth most vital cereal crop globally. Its drought resistance and robust biomass production, coupled with commendable nutritional value, make sorghum a promising choice for animal feed. Nevertheless, the utilization of sorghum in animal production faces hurdles of dhurrin (a cyanogenic glycoside) poisoning. While dhurrin serves as a protective secondary metabolite during sorghum growth, the resulting highly toxic hydrogen cyanide poses a significant threat to animal safety. This review extensively examines the biometabolic processes of dhurrin, the pivotal genes involved in the regulation of dhurrin biosynthesis, and the factors influencing dhurrin content in sorghum. It delves into the impact of dhurrin on animal production and explores measures to mitigate its content, aiming to provide insights for advancing research on dhurrin metabolism regulation in sorghum and its rational utilization in animal production.<\/jats:p>","DOI":"10.3390\/plants13162291","type":"journal-article","created":{"date-parts":[[2024,8,19]],"date-time":"2024-08-19T03:43:28Z","timestamp":1724039008000},"page":"2291","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Dhurrin in Sorghum: Biosynthesis, Regulation, Biological Function and Challenges for Animal Production"],"prefix":"10.3390","volume":"13","author":[{"given":"Bo","family":"Wang","sequence":"first","affiliation":[{"name":"Qingdao Key Laboratory of Specialty Plant Germplasm Innovation and Utilization in Saline Soils of Coastal Beach, Qingdao Agricultural University, Qingdao 266109, China"},{"name":"Key Laboratory of National Forestry and Grassland Administration on Grassland Resources and Ecology in the Yellow River Delta, Qingdao Agricultural University, Qingdao 266109, China"},{"name":"College of Grassland Science, Qingdao Agricultural University, Qingdao 266109, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wangdan","family":"Xiong","sequence":"additional","affiliation":[{"name":"Qingdao Key Laboratory of Specialty Plant Germplasm Innovation and Utilization in Saline Soils of Coastal Beach, Qingdao Agricultural University, Qingdao 266109, China"},{"name":"Key Laboratory of National Forestry and Grassland Administration on Grassland Resources and Ecology in the Yellow River Delta, Qingdao Agricultural University, Qingdao 266109, China"},{"name":"College of Grassland Science, Qingdao Agricultural University, Qingdao 266109, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7252-3041","authenticated-orcid":false,"given":"Yanjun","family":"Guo","sequence":"additional","affiliation":[{"name":"Qingdao Key Laboratory of Specialty Plant Germplasm Innovation and Utilization in Saline Soils of Coastal Beach, Qingdao Agricultural University, Qingdao 266109, China"},{"name":"Key Laboratory of National Forestry and Grassland Administration on Grassland Resources and Ecology in the Yellow River Delta, Qingdao Agricultural University, Qingdao 266109, China"},{"name":"College of Grassland Science, Qingdao Agricultural University, Qingdao 266109, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,8,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/S2095-3119(17)61728-3","article-title":"Research progress on plant tolerance to soil salinity and alkalinity in sorghum","volume":"17","author":"Huang","year":"2018","journal-title":"J. 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