{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T00:15:28Z","timestamp":1791245728775,"version":"4.1.0"},"reference-count":114,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2025,2,20]],"date-time":"2025-02-20T00:00:00Z","timestamp":1740009600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100012725","name":"Tecnol\u00f3gico Nacional de M\u00e9xico","doi-asserted-by":"publisher","award":["20024.24-P"],"award-info":[{"award-number":["20024.24-P"]}],"id":[{"id":"10.13039\/100012725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Plants"],"abstract":"<jats:p>Medicinal plants represent promising sources for the treatment of gastrointestinal disorders because of their abundance in bioactive compounds with therapeutic properties. Throughout history, various plant species have been used to alleviate digestive ailments, and studies have revealed the presence of metabolites with anti-inflammatory, antibacterial, antiviral, antiparasitic, antidiarrheal, antioxidant, and anticancer activities. The secondary metabolites responsible for these properties include alkaloids, terpenoids, and phenolic compounds, with the latter, particularly flavonoids, being the most associated with their bioactivities. Gastrointestinal diseases, such as gastritis, peptic ulcers, gastroesophageal reflux disease, inflammatory bowel disease, irritable bowel syndrome, and gastrointestinal cancer, are caused primarily by bacteria, parasites, viruses, and the consumption of raw or undercooked foods. These conditions significantly impact human health, necessitating the development of safer and more effective therapeutic alternatives. After an extensive literature review, several plant species with widespread use in the treatment of these disorders were identified, including Matricaria chamomilla, Mentha spicata, Melissa officinalis, Artemisia ludoviciana, Flourensia cernua, Phoradendron californicum, and Turnera difusa. This study revealed that the analyzed plants are rich in bioactive compounds, which confer their medicinal properties. However, many other plants commonly used to treat digestive disorders have been scarcely studied, highlighting the need for further research.<\/jats:p>","DOI":"10.3390\/plants14050642","type":"journal-article","created":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T03:47:46Z","timestamp":1740109666000},"page":"642","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Exploring the Therapeutic Potential of Medicinal Plants in the Context of Gastrointestinal Health: A Review"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-5188-7523","authenticated-orcid":false,"given":"Antonio","family":"Juli\u00e1n-Flores","sequence":"first","affiliation":[{"name":"Bioprocesses & Bioproducts Group, Food Research Department, School of Chemistry, Autonomous University of Coahuila, Saltillo 25280, Coahuila, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7983-9022","authenticated-orcid":false,"given":"Pedro","family":"Aguilar-Z\u00e1rate","sequence":"additional","affiliation":[{"name":"Laboratorio Nacional CONAHCYT de Apoyo a la Evaluaci\u00f3n de Productos Bi\u00f3ticos (LaNAEPBi), Unidad de Servicio, Tecnol\u00f3gico Nacional de M\u00e9xico\/I.T. de Ciudad Valles, Ciudad Valles 79010, San Luis Potos\u00ed, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1750-2467","authenticated-orcid":false,"given":"Mariela R.","family":"Michel","sequence":"additional","affiliation":[{"name":"Laboratorio Nacional CONAHCYT de Apoyo a la Evaluaci\u00f3n de Productos Bi\u00f3ticos (LaNAEPBi), Unidad de Servicio, Tecnol\u00f3gico Nacional de M\u00e9xico\/I.T. de Ciudad Valles, Ciudad Valles 79010, San Luis Potos\u00ed, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2596-8301","authenticated-orcid":false,"given":"Leonardo","family":"Sep\u00falveda-Torre","sequence":"additional","affiliation":[{"name":"Bioprocesses & Bioproducts Group, Food Research Department, School of Chemistry, Autonomous University of Coahuila, Saltillo 25280, Coahuila, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1614-5701","authenticated-orcid":false,"given":"Cristian","family":"Torres-Le\u00f3n","sequence":"additional","affiliation":[{"name":"Research Center and Ethnobiological Garden, Autonomous University of Coahuila, Viesca 27480, Coahuila, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5867-8672","authenticated-orcid":false,"given":"Crist\u00f3bal N.","family":"Aguilar","sequence":"additional","affiliation":[{"name":"Bioprocesses & Bioproducts Group, Food Research Department, School of Chemistry, Autonomous University of Coahuila, Saltillo 25280, Coahuila, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6535-2558","authenticated-orcid":false,"given":"M\u00f3nica L.","family":"Ch\u00e1vez-Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Bioprocesses & Bioproducts Group, Food Research Department, School of Chemistry, Autonomous University of Coahuila, Saltillo 25280, Coahuila, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,2,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"103698","DOI":"10.1016\/j.ridd.2020.103698","article-title":"Relationship between parent-reported gastrointestinal symptoms, sleep problems, autism spectrum disorder symptoms, and behavior problems in children and adolescents with 22q11.2 deletion syndrome","volume":"104","author":"Leader","year":"2020","journal-title":"Res. 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