{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T22:34:49Z","timestamp":1787870089984,"version":"build-2784847793"},"reference-count":172,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2025,5,24]],"date-time":"2025-05-24T00:00:00Z","timestamp":1748044800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"\u201cVictor Babe\u0219\u201d University of Medicine and Pharmacy Timisoara"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Plants"],"abstract":"<jats:p>The Rosaceae family, comprising over 3000 species, has been extensively investigated for its therapeutic potential, particularly in dermatological applications. Skin illnesses have become in recent years a serious burden worldwide, with more than 3 billion individuals of all ages affected by a skin condition. This review focuses on approximately 50 species from genera such as Rosa, Rubus, Prunus, Potentilla, and especially Eriobotrya japonica, which have shown promising biological effects due to their diverse bioactive compounds. This review provides a current perspective on the recent scientific literature that highlights the role of Rosaceae members in managing various skin disorders. Key dermatological conditions addressed include dermatitis, acne, skin aging, melanoma, and psoriasis. By summarizing both in vitro and in vivo findings, this review underscores the importance of Rosaceae species in the development of plant-based dermatological therapies and encourages further research into their mechanisms of action and clinical potential.<\/jats:p>","DOI":"10.3390\/plants14111605","type":"journal-article","created":{"date-parts":[[2025,5,25]],"date-time":"2025-05-25T20:16:22Z","timestamp":1748204182000},"page":"1605","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Biological Effects of Rosaceae Species in Skin Disorders\u2014An Up-To-Date Overview"],"prefix":"10.3390","volume":"14","author":[{"given":"Andreea Maria","family":"Cristea","sequence":"first","affiliation":[{"name":"University Clinic of Toxicology, Drug Industry, Management and Legislation, Faculty of Pharmacy, \u201cVictor Babes\u201d University of Medicine and Pharmacy, 2nd Eftimie Murgu Square, 300041 Timisoara, Romania"},{"name":"Research Centre for Pharmaco-Toxicological Evaluation, Faculty of Pharmacy, \u201cVictor Babes\u201d University of Medicine and Pharmacy, 2nd Eftimie Murgu Square, 300041 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreea","family":"Smeu","sequence":"additional","affiliation":[{"name":"University Clinic of Toxicology, Drug Industry, Management and Legislation, Faculty of Pharmacy, \u201cVictor Babes\u201d University of Medicine and Pharmacy, 2nd Eftimie Murgu Square, 300041 Timisoara, Romania"},{"name":"Research Centre for Pharmaco-Toxicological Evaluation, Faculty of Pharmacy, \u201cVictor Babes\u201d University of Medicine and Pharmacy, 2nd Eftimie Murgu Square, 300041 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ioan-Alexandru","family":"C\u00eempeanu","sequence":"additional","affiliation":[{"name":"Doctoral School, \u201cVictor Babes\u201d University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrada","family":"Iftode","sequence":"additional","affiliation":[{"name":"University Clinic of Toxicology, Drug Industry, Management and Legislation, Faculty of Pharmacy, \u201cVictor Babes\u201d University of Medicine and Pharmacy, 2nd Eftimie Murgu Square, 300041 Timisoara, Romania"},{"name":"Research Centre for Pharmaco-Toxicological Evaluation, Faculty of Pharmacy, \u201cVictor Babes\u201d University of Medicine and Pharmacy, 2nd Eftimie Murgu Square, 300041 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4866-934X","authenticated-orcid":false,"given":"Sergio","family":"Liga","sequence":"additional","affiliation":[{"name":"Department of Applied Chemistry and Engineering of Organic and Natural Compounds, Faculty of Chemical Engineering, Biotechnologies and Environmental Protection, Politehnica University Timisoara, Vasile P\u00e2rvan No. 6, 300223 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8107-8595","authenticated-orcid":false,"given":"Diana-Simona","family":"Tchiakpe-Antal","sequence":"additional","affiliation":[{"name":"Research Centre for Pharmaco-Toxicological Evaluation, Faculty of Pharmacy, \u201cVictor Babes\u201d University of Medicine and Pharmacy, 2nd Eftimie Murgu Square, 300041 Timisoara, Romania"},{"name":"Department of Pharmaceutical Botany, Faculty of Pharmacy, \u201cVictor Babes\u201d University of Medicine and Pharmacy, 2nd Eftimie Murgu Square, 300041 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daliborca","family":"Vlad","sequence":"additional","affiliation":[{"name":"Biochemistry and Pharmacology Department, Discipline of Pharmacology, \u201cVictor Babes\u201d University of Medicine and Pharmacy, 300041 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina Adriana","family":"Dehelean","sequence":"additional","affiliation":[{"name":"University Clinic of Toxicology, Drug Industry, Management and Legislation, Faculty of Pharmacy, \u201cVictor Babes\u201d University of Medicine and Pharmacy, 2nd Eftimie Murgu Square, 300041 Timisoara, Romania"},{"name":"Research Centre for Pharmaco-Toxicological Evaluation, Faculty of Pharmacy, \u201cVictor Babes\u201d University of Medicine and Pharmacy, 2nd Eftimie Murgu Square, 300041 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Iliescu","sequence":"additional","affiliation":[{"name":"University Clinic of Surgical Semiology I and Thoracic Surgery, Faculty of Medicine, \u201cVictor Babes\u201d University of Timisoara, 2 Eftimie Murgu Square, 300041 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,5,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1111\/jdv.18050","article-title":"Prevalence of most common skin diseases in Europe: A population-based study","volume":"36","author":"Richard","year":"2022","journal-title":"J. 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