{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T07:23:34Z","timestamp":1790148214718,"version":"4.0.1"},"reference-count":77,"publisher":"MDPI AG","issue":"16","license":[{"start":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T00:00:00Z","timestamp":1755734400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico (CNPq)","award":["88887.606273\/2021-00"],"award-info":[{"award-number":["88887.606273\/2021-00"]}]},{"name":"Funda\u00e7\u00e3o Arauc\u00e1ria","award":["88887.606273\/2021-00"],"award-info":[{"award-number":["88887.606273\/2021-00"]}]},{"name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior (CAPES)","award":["88887.606273\/2021-00"],"award-info":[{"award-number":["88887.606273\/2021-00"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Plants"],"abstract":"<jats:p>The native fruits of the Cerrado have an interesting composition of bioactive compounds responsible for antioxidant, anti-inflammatory, and antimicrobial activities, with technological potential for functional industries. This study investigated the extraction of bioactive compounds in cagaita and mamacadela fruits, under different conditions, using eutectic solvents based on choline chloride (CC) with citric acid (CA) or tartaric acid (TA), plus ethanol as reference. For a better understanding of the extracts, their antioxidant capacity was assessed by the DPPH\u2022, FRAP, ABTS\u2022+, and total phenolic compounds and flavonoids assays, as well as for color, water activity, and identification of bioactive compounds by mass spectrometry. Additionally, the carotenoid contents were evaluated in the ethanolic extracts. The results showed that ethanol was efficient for the extraction of flavonoids and presented advantages demonstrated in the antioxidant analyses of ABTS\u2022+ and FRAP. However, eutectic solvents stood out in the extraction of phenolic compounds, with yields 14.0 and 4.5 times higher than ethanol for mamacadela and cagaita, respectively. In addition, when compared to cagaita, mamacadela had twice the carotenoid content. Furthermore, the CC:TA solvent was the most efficient, demonstrating, by DI-ESI-MS, 29 phenolic compounds in mamacadela and 27 in cagaita. Therefore, the extracts obtained present potential for use as natural pigments, adding value to the fruits and encouraging their exploration by industries.<\/jats:p>","DOI":"10.3390\/plants14162596","type":"journal-article","created":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T08:02:44Z","timestamp":1755763364000},"page":"2596","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Enhanced Recovery of Bioactive Compounds from Cagaita and Mamacadela Fruits Using Natural Deep Eutectic Solvents (NADES) and Ethanol: A Comparative Study"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5271-3182","authenticated-orcid":false,"given":"Jaqueline Ferreira","family":"Silva","sequence":"first","affiliation":[{"name":"Postgraduate in Food Sciences, State University of Maring\u00e1, Maring\u00e1 87020-000, Paran\u00e1, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen Torres","family":"Guedes","sequence":"additional","affiliation":[{"name":"Postgraduate in Food Engineering, State University of Maring\u00e1, Maring\u00e1 87020-000, Paran\u00e1, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eloize da Silva","family":"Alves","sequence":"additional","affiliation":[{"name":"Postgraduate in Food Sciences, State University of Maring\u00e1, Maring\u00e1 87020-000, Paran\u00e1, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8208-0950","authenticated-orcid":false,"given":"\u00c9velin Lemos de","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Department of Chemistry, State University of Maring\u00e1, Maring\u00e1 87020-000, Paran\u00e1, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4835-7773","authenticated-orcid":false,"given":"Eduardo Cesar","family":"Meurer","sequence":"additional","affiliation":[{"name":"Food Engineering, Federal University Paran\u00e1, Jandaia do Sul 86900-000, Paran\u00e1, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suelen Siqueira dos","family":"Santos","sequence":"additional","affiliation":[{"name":"Food Engineering, Federal University Paran\u00e1, Jandaia do Sul 86900-000, Paran\u00e1, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7818-6624","authenticated-orcid":false,"given":"M\u00f4nica Regina da Silva","family":"Scapim","sequence":"additional","affiliation":[{"name":"Food Engineering Departament, State University of Maring\u00e1, Maring\u00e1 87020-000, Paran\u00e1, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1204-525X","authenticated-orcid":false,"given":"Grasiele Scaramal","family":"Madrona","sequence":"additional","affiliation":[{"name":"Food Engineering Departament, State University of Maring\u00e1, Maring\u00e1 87020-000, Paran\u00e1, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,8,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"167581","DOI":"10.1016\/j.scitotenv.2023.167581","article-title":"Landscape Changes in the Cerrado: Challenges of Land Clearing, Fragmentation and Land Tenure for Biological Conservation","volume":"906","author":"Pompeu","year":"2024","journal-title":"Sci. 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