{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T03:17:42Z","timestamp":1792034262682,"version":"4.4.0"},"reference-count":60,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T00:00:00Z","timestamp":1759968000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"European Union\u2014Next-GenerationEU","award":["FAR PNR\u2014DM 737\/2021\u2014BEE-HON"],"award-info":[{"award-number":["FAR PNR\u2014DM 737\/2021\u2014BEE-HON"]}]},{"name":"European Union\u2014Next-GenerationEU","award":["CUP N. J15F22000020001"],"award-info":[{"award-number":["CUP N. J15F22000020001"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Plants"],"abstract":"<jats:p>The aim of this study was to present a comprehensive analysis of honey varieties from different botanical origins, focusing on their phenolic compounds\u2019 composition, volatile profiles, and antioxidant activity. We simultaneously identified and quantified 37 bioactive compounds, including anthocyanins, flavonols, flavones, flavan-3-ols, proanthocyanidins, and phenolic acids, across various honey samples by HPLC-MS\/MS. Total phenolic content (TPC), total flavonoid content (TFC), and antioxidant activity (AOA) were determined using UV-Vis spectrophotometric analysis. The content of phenolic compounds quantified by HPLC-MS\/MS ranged from 19.56 to 243.94 mg\u00b7kg\u22121, highlighting a high presence of these antioxidant compounds (mainly phenolic acids), confirmed also by the positive correlation between TPC and DPPH values. Among volatiles compounds, analyzed by HS-SPME-GC-MS, benzene acetaldehyde and furfural resulted specific for two types of honey samples (H-7 and H-9), highlighting the possibility of searching for chemical markers to characterize honeys of different specie\/origin. This study enhances our understanding of the bioactive potential of honey from different botanical origins and provides a foundation for future research on its health benefits.<\/jats:p>","DOI":"10.3390\/plants14193109","type":"journal-article","created":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T13:19:26Z","timestamp":1760015966000},"page":"3109","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Analysis of the Phenolic Compounds, Volatile Profile, and Evaluation of the Antioxidant Activity of 18 Different Varieties of Honey from the Italian Market"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6053-3712","authenticated-orcid":false,"given":"Doaa","family":"Abouelenein","sequence":"first","affiliation":[{"name":"Chemistry Interdisciplinary Project (ChIP) Research Center, School of Pharmacy, University of Camerino, Via Madonna Delle Carceri, 62032 Camerino, Italy"},{"name":"Research Group of Analytical Food Chemistry, National Food Institute, Technical University of Denmark (DTU), Kemitorvet 202, DK-2800 Lyngby, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4158-5346","authenticated-orcid":false,"given":"Laura","family":"Acquaticci","sequence":"additional","affiliation":[{"name":"Chemistry Interdisciplinary Project (ChIP) Research Center, School of Pharmacy, University of Camerino, Via Madonna Delle Carceri, 62032 Camerino, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1216-1368","authenticated-orcid":false,"given":"Eleonora","family":"Spinozzi","sequence":"additional","affiliation":[{"name":"Chemistry Interdisciplinary Project (ChIP) Research Center, School of Pharmacy, University of Camerino, Via Madonna Delle Carceri, 62032 Camerino, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0497-8386","authenticated-orcid":false,"given":"Agnese","family":"Santanatoglia","sequence":"additional","affiliation":[{"name":"Chemistry Interdisciplinary Project (ChIP) Research Center, School of Pharmacy, University of Camerino, Via Madonna Delle Carceri, 62032 Camerino, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5211-6986","authenticated-orcid":false,"given":"Gulzhan","family":"Khamitova","sequence":"additional","affiliation":[{"name":"Chemistry Interdisciplinary Project (ChIP) Research Center, School of Pharmacy, University of Camerino, Via Madonna Delle Carceri, 62032 Camerino, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1533-1553","authenticated-orcid":false,"given":"Ahmed M.","family":"Mustafa","sequence":"additional","affiliation":[{"name":"Chemistry Interdisciplinary Project (ChIP) Research Center, School of Pharmacy, University of Camerino, Via Madonna Delle Carceri, 62032 Camerino, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6916-7915","authenticated-orcid":false,"given":"Marco","family":"Cespi","sequence":"additional","affiliation":[{"name":"Chemistry Interdisciplinary Project (ChIP) Research Center, School of Pharmacy, University of Camerino, Via Madonna Delle Carceri, 62032 Camerino, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5258-6742","authenticated-orcid":false,"given":"Silvia","family":"Preziuso","sequence":"additional","affiliation":[{"name":"School of Biosciences and Veterinary Medicine, University of Camerino, Via Circonvallazione 93\/95, 62024 Matelica, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Bianchi","sequence":"additional","affiliation":[{"name":"FAR Project Bee-Hon, School of Pharmacy, University of Camerino, 62032 Camerino, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1375-4744","authenticated-orcid":false,"given":"Filippo","family":"Maggi","sequence":"additional","affiliation":[{"name":"Chemistry Interdisciplinary Project (ChIP) Research Center, School of Pharmacy, University of Camerino, Via Madonna Delle Carceri, 62032 Camerino, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5530-877X","authenticated-orcid":false,"given":"Giovanni","family":"Caprioli","sequence":"additional","affiliation":[{"name":"Chemistry Interdisciplinary Project (ChIP) Research Center, School of Pharmacy, University of Camerino, Via Madonna Delle Carceri, 62032 Camerino, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,10,9]]},"reference":[{"key":"ref_1","unstructured":"S\u00e1nchez, C., Castignani, H., and Rabaglio, M. 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