{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T18:35:12Z","timestamp":1779129312702,"version":"3.51.4"},"reference-count":72,"publisher":"MDPI AG","issue":"21","license":[{"start":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T00:00:00Z","timestamp":1761782400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"AYSS JINR","award":["24-401-07"],"award-info":[{"award-number":["24-401-07"]}]},{"name":"Joint Institute for Nuclear Research-South Africa project","award":["37"],"award-info":[{"award-number":["37"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Plants"],"abstract":"<jats:p>Metal nanoparticles are increasingly used in industry and agriculture to enhance crop yields and combat plant diseases. Their widespread application has led to exposure across all ecosystem components, including humans. However, there is a lack of a comprehensive assessment of the effect of copper nanoparticles on spearmint plants, applied in different ways (root and foliar) in a wide range of concentrations. The effect of copper nanoparticles at the concentration range of 1\u2013100 mg\/L on Mentha spicata L. plants under root exposure and foliar spraying conditions was studied during a 28-day experiment. Copper content in soil and spearmint segments was determined using inductively coupled plasma atomic emission spectroscopy, while the morphology of nanoparticles was characterized using transmission electron microscopy. Foliar spraying showed an inverse relationship between the concentration of copper in solution and root uptake. The highest copper uptake in roots of 27.51 mg\/kg was attained at a nanoparticle concentration of 1 mg\/L. Root exposure inhibited soil microbial activity, with copper mainly accumulating in soil (up to 950.2 mg\/kg) and roots (up to 150.5 mg\/kg). Both application methods stimulated pigment production and antioxidant activity, with root irrigation showing a more pronounced effect. Copper extraction efficiency varied (3\u201364%) depending on exposure method and concentration, raising concerns about transfer along the food chain. Health risk assessment associated with consumption of herbal infusions, prepared from copper-contaminated spearmint leaves, did not show adverse effects when copper levels in the infusion remained below 1.53 mg\/L.<\/jats:p>","DOI":"10.3390\/plants14213318","type":"journal-article","created":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T02:48:28Z","timestamp":1761878908000},"page":"3318","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Features of Translocation of Copper Nanoparticles in Mentha spicata L. and Extraction into Infusion"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5020-0500","authenticated-orcid":false,"given":"Alexandra","family":"Peshkova","sequence":"first","affiliation":[{"name":"Joint Institute for Nuclear Research, 6 Joliot-Curie Str., 141980 Dubna, Russia"},{"name":"Doctoral School of Natural Sciences, Moldova State University, M. Kogalniceanu Str., 75A, MD-2009 Chisinau, Moldova"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0820-887X","authenticated-orcid":false,"given":"Inga","family":"Zinicovscaia","sequence":"additional","affiliation":[{"name":"Joint Institute for Nuclear Research, 6 Joliot-Curie Str., 141980 Dubna, Russia"},{"name":"Horia Hulubei National Institute for R&D in Physics and Nuclear Engineering, 30 Reactorului Str., 077125 M\u0103gurele, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7516-948X","authenticated-orcid":false,"given":"Liliana","family":"Cepoi","sequence":"additional","affiliation":[{"name":"Institute of Microbiology and Biotechnology, Technical University of Moldova, 1 Academiei Str., MD-2028 Chisinau, Moldova"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0752-8153","authenticated-orcid":false,"given":"Ludmila","family":"Rudi","sequence":"additional","affiliation":[{"name":"Institute of Microbiology and Biotechnology, Technical University of Moldova, 1 Academiei Str., MD-2028 Chisinau, Moldova"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2933-0751","authenticated-orcid":false,"given":"Tatiana","family":"Chiriac","sequence":"additional","affiliation":[{"name":"Institute of Microbiology and Biotechnology, Technical University of Moldova, 1 Academiei Str., MD-2028 Chisinau, Moldova"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0099-8590","authenticated-orcid":false,"given":"Serghei","family":"Corcimaru","sequence":"additional","affiliation":[{"name":"Institute of Microbiology and Biotechnology, Technical University of Moldova, 1 Academiei Str., MD-2028 Chisinau, Moldova"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5650-4337","authenticated-orcid":false,"given":"Nikita","family":"Yushin","sequence":"additional","affiliation":[{"name":"Joint Institute for Nuclear Research, 6 Joliot-Curie Str., 141980 Dubna, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9039-7010","authenticated-orcid":false,"given":"Rikus","family":"le Roux","sequence":"additional","affiliation":[{"name":"School for Science and Technology, Faculty of Military Science, Stellenbosch University, Saldanha 7395, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,10,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Michaela Corina, C., Teodora, M., and Lucian, M. 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