{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T13:38:51Z","timestamp":1790948331944,"version":"4.1.0"},"reference-count":58,"publisher":"MDPI AG","issue":"24","license":[{"start":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T00:00:00Z","timestamp":1764892800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Major Special Science and Technology Project of Anhui Province","award":["202303a07020005"],"award-info":[{"award-number":["202303a07020005"]}]},{"name":"Traditional Chinese Medicine high-level key discipline construction project of National Administration of Traditional Chinese Medicine\u2014Science of Chinese medicinal material resources","award":["zyyzdxk-2023095"],"award-info":[{"award-number":["zyyzdxk-2023095"]}]},{"name":"Scientific Research Team Program of Anhui Colleges and Universities","award":["2022AH010036"],"award-info":[{"award-number":["2022AH010036"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Plants"],"abstract":"<jats:p>Dendrobium huoshanense, a rare and endangered medicinal orchid species endemic to Huoshan County, Anhui Province, faces a severe limit of wild resources. Its medicinal efficacy derives from unique chemical constituents, which vary significantly across cultivation modes. We systematically compared sensory properties and nutritional constituents (polysaccharides, flavonoids, alkaloids, bibenzyls, minerals, and free amino acids) between D. huoshanense in three cultivation modes\u2014greenhouse cultivation, understory gravel cultivation, and wild-simulated cultivation. Additionally, the gastroprotective effects of wild-simulated cultivated D. huoshanense on gastric mucosal epithelial cells were evaluated. Results demonstrated that wild-simulated cultivation yielded significantly higher levels of nutritional constituents compared to gravel and greenhouse cultivation. Furthermore, wild-simulated cultivated D. huoshanense exhibited notable protective effects against gastric mucosal epithelial cell damage. This study not only elucidates the influence of cultivation modes on the chemical profile of D. huoshanense but also provides scientific evidence supporting its gastric protective properties, offering a foundation for its sustainable utilization and quality-oriented cultivation.<\/jats:p>","DOI":"10.3390\/plants14243718","type":"journal-article","created":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T15:11:24Z","timestamp":1764947484000},"page":"3718","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Quality Evaluation of Dendrobium huoshanense Under Different Cultivation Modes and Its Protective Effect on Ethanol-Induced Injury in GES-1 Cells"],"prefix":"10.3390","volume":"14","author":[{"given":"Xinxin","family":"Li","sequence":"first","affiliation":[{"name":"College of Pharmacy, Anhui University of Chinese Medicine, Hefei 230012, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziting","family":"Zhu","sequence":"additional","affiliation":[{"name":"College of Pharmacy, Anhui University of Chinese Medicine, Hefei 230012, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Wu","sequence":"additional","affiliation":[{"name":"College of Pharmacy, Anhui University of Chinese Medicine, Hefei 230012, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nianjun","family":"Yu","sequence":"additional","affiliation":[{"name":"College of Pharmacy, Anhui University of Chinese Medicine, Hefei 230012, China"},{"name":"Ministry of Education-Anhui Joint Collaborative Innovation Center for Quality Improvement of Anhui Genuine Chinese Medicinal Materials, Hefei 230012, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huiqun","family":"Xie","sequence":"additional","affiliation":[{"name":"College of Pharmacy, Anhui University of Chinese Medicine, Hefei 230012, China"},{"name":"Ministry of Education-Anhui Joint Collaborative Innovation Center for Quality Improvement of Anhui Genuine Chinese Medicinal Materials, Hefei 230012, China"},{"name":"Institute of Traditional Chinese Medicine Resources Protection and Development, Anhui Academy of Chinese Medicine, Hefei 230012, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lan","family":"Han","sequence":"additional","affiliation":[{"name":"College of Pharmacy, Anhui University of Chinese Medicine, Hefei 230012, China"},{"name":"Ministry of Education-Anhui Joint Collaborative Innovation Center for Quality Improvement of Anhui Genuine Chinese Medicinal Materials, Hefei 230012, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daiyin","family":"Peng","sequence":"additional","affiliation":[{"name":"College of Pharmacy, Anhui University of Chinese Medicine, Hefei 230012, China"},{"name":"Ministry of Education-Anhui Joint Collaborative Innovation Center for Quality Improvement of Anhui Genuine Chinese Medicinal Materials, Hefei 230012, China"},{"name":"Institute of Traditional Chinese Medicine Resources Protection and Development, Anhui Academy of Chinese Medicine, Hefei 230012, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,12,5]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Li, M., Trapika, I., Tang, S.Y.S., Cho, J.L., Qi, Y., Li, C.G., Li, Y., Yao, M., Yang, D., and Liu, B. 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