{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T18:34:07Z","timestamp":1787164447252,"version":"build-2736575974"},"reference-count":107,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T00:00:00Z","timestamp":1768521600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Plants"],"abstract":"<jats:p>Antimicrobial resistance represents a critical challenge to global public health, driving the search for bioactive compounds in medicinal plants. The Fabaceae family stands out for its chemical richness and pharmacological properties; however, in the state of Tamaulipas, Mexico\u2014an area of high diversity due to its location between the Nearctic and Neotropical regions\u2014this flora remains largely unexplored. The objective of this review was to analyze the global scientific literature on the Fabaceae of Tamaulipas, integrating floristic records, phytochemistry, and antimicrobial activity. Of the 347 species recorded in the state, only 60 have phytochemical studies, and 43 have documented medicinal uses. The results show that extraction methods predominantly use polar solvents to isolate phenolic compounds, flavonoids, and alkaloids, which show efficacy against pathogens such as Staphylococcus aureus, Escherichia coli, and Candida albicans. Despite limited local ethnobotanical documentation, the potential demonstrated by these species in other regions positions Tamaulipas as a strategic reservoir. This review identifies research gaps and emphasizes the need for systematic studies that validate traditional uses and prioritize bioprospecting of the flora of northeastern Mexico for the development of new therapeutic alternatives.<\/jats:p>","DOI":"10.3390\/plants15020278","type":"journal-article","created":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T14:46:33Z","timestamp":1768574793000},"page":"278","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Phytochemical Diversity and Antimicrobial Potential of Fabaceae Species Occurring in Tamaulipas, Mexico: A Systematic Review"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-6417-5323","authenticated-orcid":false,"given":"Paulina Rachel","family":"Guti\u00e9rrez-Dur\u00e1n","sequence":"first","affiliation":[{"name":"Instituto Tecnol\u00f3gico de Ciudad Victoria, Tecnol\u00f3gico Nacional de M\u00e9xico\/Instituto Tecnol\u00f3gico de Ciudad Victoria, Avenida Tecnol\u00f3gico No. 1301, C.P., Ciudad Victoria 87010, Mexico"},{"name":"Departamento de Bacteriolog\u00eda, Facultad de Medicina Veterinaria y Zootecnia, Universidad Aut\u00f3noma de Tamaulipas, Carretera Victoria-Mante km. 5 A.P. N\u00b0 263, C.P., Ciudad Victoria 87000, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5360-2684","authenticated-orcid":false,"given":"Jorge V\u00edctor","family":"Horta-Vega","sequence":"additional","affiliation":[{"name":"Instituto Tecnol\u00f3gico de Ciudad Victoria, Tecnol\u00f3gico Nacional de M\u00e9xico\/Instituto Tecnol\u00f3gico de Ciudad Victoria, Avenida Tecnol\u00f3gico No. 1301, C.P., Ciudad Victoria 87010, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8470-3843","authenticated-orcid":false,"given":"Fabi\u00e1n Eliseo","family":"Olazar\u00e1n-Santib\u00e1\u00f1ez","sequence":"additional","affiliation":[{"name":"Departamento de Bacteriolog\u00eda, Facultad de Medicina Veterinaria y Zootecnia, Universidad Aut\u00f3noma de Tamaulipas, Carretera Victoria-Mante km. 5 A.P. N\u00b0 263, C.P., Ciudad Victoria 87000, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3490-6391","authenticated-orcid":false,"given":"Juan","family":"Flores-Gracia","sequence":"additional","affiliation":[{"name":"Instituto Tecnol\u00f3gico de Ciudad Victoria, Tecnol\u00f3gico Nacional de M\u00e9xico\/Instituto Tecnol\u00f3gico de Ciudad Victoria, Avenida Tecnol\u00f3gico No. 1301, C.P., Ciudad Victoria 87010, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7590-319X","authenticated-orcid":false,"given":"Hugo Br\u00edgido","family":"Barrios-Garc\u00eda","sequence":"additional","affiliation":[{"name":"Departamento de Bacteriolog\u00eda, Facultad de Medicina Veterinaria y Zootecnia, Universidad Aut\u00f3noma de Tamaulipas, Carretera Victoria-Mante km. 5 A.P. N\u00b0 263, C.P., Ciudad Victoria 87000, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,1,16]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"429","DOI":"10.4014\/jmb.1608.08024","article-title":"Antimicrobial Activity of Basil, Oregano, and Thyme Essential Oils","volume":"27","author":"Sakkas","year":"2017","journal-title":"J. Microbiol. Biotechnol."},{"key":"ref_2","unstructured":"Rodr\u00edguez-Flores, O.R., Centeno, E.A., and Betanco, R.A. (2005). Plantas Utilizadas Para el Tratamiento de Enfermedades en los Animales Dom\u00e9sticos, Reserva Natural El Tisey."},{"key":"ref_3","unstructured":"Organizaci\u00f3n Mundial de la Salud (2025). Cuidados Innovadores Para las Condiciones Cr\u00f3nicas, Organizaci\u00f3n Mundial de la Salud."},{"key":"ref_4","unstructured":"Organizaci\u00f3n Mundial de Sanidad Animal (2025). 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