{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T17:46:56Z","timestamp":1782496016399,"version":"3.54.5"},"reference-count":77,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T00:00:00Z","timestamp":1771891200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005375","name":"Latvian Council of Science","doi-asserted-by":"publisher","award":["lzp-2020\/1-0422"],"award-info":[{"award-number":["lzp-2020\/1-0422"]}],"id":[{"id":"10.13039\/501100005375","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Plants"],"abstract":"<jats:p>Inspired by the lack of wide-scale family level screenings, the profile of tocochromanols in Berberidaceae family species belonging to the Berberis, Mahonia, Caulophyllum, Jeffersonia and Podophyllum genera was studied. Seeds were acquired from botanical gardens around the world and tocopherol and tocotrienol content was tested using ultrasound-assisted extraction in ethanol (UAEE) and compared to saponification protocol and analyzed by an RP-HPLC-FLD system. The UAEE protocol produced 93% average tocochromanol recovery compared to the saponification protocol. All investigated samples were tocotrienol-dominated, the lowest proportions being in B. regeliana, B. thunbergii and B. aristata at means of 55%, 56% and 58%, respectively. The main tocochromanol constituents were \u03b1-tocotrienol and \u03b3-tocotrienol. The highest \u03b1-tocotrienol content was observed in B. tchonskyana at 9.14 mg 100 g\u22121 dw, and the highest \u03b3-tocotrienol and sum of free tocochromanol content was observed in J. diphylla at 18.00 and 23.76 mg 100 g\u22121 dw, respectively. Principal component analysis and k-means cluster analysis based on a free tocochromanol profile indicated \u03b3-tocotrienol and \u03b1-tocotrienol content as the main differentiators. However, a comprehensive sample set could only be collected for the Berberis genus, warranting further research into Berberidaceae seed tocochromanols.<\/jats:p>","DOI":"10.3390\/plants15050676","type":"journal-article","created":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T15:05:27Z","timestamp":1771945527000},"page":"676","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Tocotrienol-Dominated Berberidaceae Species\u2019 Seed Tocochromanols: Screening via Ultrasound-Assisted Extraction in Ethanol"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8083-8676","authenticated-orcid":false,"given":"Danija","family":"Lazdi\u0146a","sequence":"first","affiliation":[{"name":"Institute of Horticulture, Graudu 1, LV-3701 Dobele, Latvia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5764-0143","authenticated-orcid":false,"given":"Inga","family":"Mi\u0161ina","sequence":"additional","affiliation":[{"name":"Institute of Horticulture, Graudu 1, LV-3701 Dobele, Latvia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-1281-8200","authenticated-orcid":false,"given":"Krists","family":"Dukurs","sequence":"additional","affiliation":[{"name":"Institute of Horticulture, Graudu 1, LV-3701 Dobele, Latvia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3908-2296","authenticated-orcid":false,"given":"Pawe\u0142","family":"G\u00f3rna\u015b","sequence":"additional","affiliation":[{"name":"Institute of Horticulture, Graudu 1, LV-3701 Dobele, Latvia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,2,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Salehi, B., Selamoglu, Z., Sener, B., Kilic, M., Kumar Jugran, A., de Tommasi, N., Sinisgalli, C., Milella, L., Rajkovic, J., and Flaviana, B. (2019). Berberis plants\u2014Drifting from farm to food applications, phytotherapy, and phytopharmacology. Foods, 8.","DOI":"10.3390\/foods8100522"},{"key":"ref_2","unstructured":"Royal Botanic Gardens, K (2026, February 05). Berberidaceae Juss. Available online: https:\/\/powo.science.kew.org\/taxon\/urn:lsid:ipni.org:names:30000989-2\/general-information."},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Och, A., Podg\u00f3rski, R., and Nowak, R. (2020). Biological activity of berberine\u2014A summary update. Toxins, 12.","DOI":"10.3390\/toxins12110713"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"111188","DOI":"10.1016\/j.colsurfb.2020.111188","article-title":"Nano-based delivery systems for berberine: A modern anti-cancer herbal medicine","volume":"194","author":"Majidzadeh","year":"2020","journal-title":"Colloids Surf. B"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.ejphar.2015.05.068","article-title":"Current knowledge and pharmacological profile of berberine: An update","volume":"761","author":"Kumar","year":"2015","journal-title":"Eur. J. Pharmacol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1007\/s12161-021-02136-8","article-title":"Berberis vulgaris fruit: Determination of phenolic compounds in extracts obtained by supercritical CO2 and soxhlet methods using HPLC","volume":"15","year":"2022","journal-title":"Food Anal. Methods"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1080\/0735-260291044179","article-title":"The function of tocopherols and tocotrienols in plants","volume":"21","author":"Alegre","year":"2002","journal-title":"Crit. Rev. Plant Sci."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1002\/ejlt.201300319","article-title":"An alternative RP-HPLC method for the separation and determination of tocopherol and tocotrienol homologues as butter authenticity markers: A comparative study between two European countries","volume":"116","author":"Siger","year":"2014","journal-title":"Eur. J. Lipid Sci. Technol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.foodcont.2016.06.011","article-title":"Free tocopherols as chemical markers for Arabica coffee adulteration with maize and coffee by-products","volume":"70","author":"Tavares","year":"2016","journal-title":"Food Control"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1016\/j.phytochem.2006.04.004","article-title":"Differential distribution of tocopherols and tocotrienols in photosynthetic and non-photosynthetic tissues","volume":"67","author":"Horvath","year":"2006","journal-title":"Phytochemistry"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.foodchem.2019.05.185","article-title":"Less widespread plant oils as a good source of vitamin E","volume":"296","author":"Trela","year":"2019","journal-title":"Food Chem."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"112386","DOI":"10.1016\/j.foodres.2022.112386","article-title":"Free tocopherols and tocotrienols in 82 plant species\u2019 oil: Chemotaxonomic relation as demonstrated by PCA and HCA","volume":"164","author":"Siger","year":"2023","journal-title":"Food Res. Int."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"107535","DOI":"10.1016\/j.jfca.2025.107535","article-title":"Domination of tocotrienols over tocopherols in seed oils of sixteen species belonging to the Apiaceae family","volume":"142","year":"2025","journal-title":"J. Food Compos. Anal."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1080\/12538078.2007.10516050","article-title":"Fatty acids and tocochromanol patterns of some Turkish Apiaceae (Umbelliferae) plants; a chemotaxonomic approach","volume":"154","author":"Bagci","year":"2007","journal-title":"Acta Bot. Gall."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1002\/lipi.19950970107","article-title":"Untersuchungen \u00fcber die tocopherol-und tocotrienolzusammensetzung der samen\u00f6le einiger vertreter der familie Apiaceae","volume":"97","author":"Ivanov","year":"1995","journal-title":"Lipid\/Fett"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0031-9422(03)00300-5","article-title":"Evolution of secondary metabolites from an ecological and molecular phylogenetic perspective","volume":"64","author":"Wink","year":"2003","journal-title":"Phytochemistry"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/BF00983210","article-title":"A chemotaxonomical study of some Boraginaceae: Pyrrolizidine alkaloids and phenolic compounds","volume":"137","author":"Huizing","year":"1981","journal-title":"Plant Syst. Evol."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.bse.2018.09.002","article-title":"Survey of pyrrolizidine alkaloids in the tribe Lithospermeae (Boraginaceae) from Pan-Himalaya and their chemotaxonomic significance","volume":"81","author":"Ahmad","year":"2018","journal-title":"Biochem. Syst. Ecol."},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"Hajib, A., El Harkaoui, S., Choukri, H., Khouchlaa, A., Aourabi, S., El Menyiy, N., Bouyahya, A., and Matthaeus, B. (2023). Apiaceae family an important source of petroselinic fatty acid: Abundance, biosynthesis, chemistry, and biological proprieties. Biomolecules, 13.","DOI":"10.3390\/biom13111675"},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"Lazdi\u0146a, D., Mi\u0161ina, I., and G\u00f3rna\u015b, P. (2025). Tocotrienols in eleven species of Hypericum genus leaves. Molecules, 30.","DOI":"10.3390\/molecules30030662"},{"key":"ref_21","doi-asserted-by":"crossref","unstructured":"Mi\u0161ina, I., Lazdi\u0146a, D., and G\u00f3rna\u015b, P. (2025). Tocochromanols in the leaves of plants in the Hypericum and Clusia genera. Molecules, 30.","DOI":"10.3390\/molecules30030709"},{"key":"ref_22","doi-asserted-by":"crossref","unstructured":"Lazdi\u0146a, D., Mi\u0137elsone, I., Mi\u0161ina, I., Dukurs, K., Ben\u00edtez-Gonz\u00e1lez, A.M., Stinco, C.M., Mel\u00e9ndez-Mart\u00ednez, A.J., and G\u00f3rna\u015b, P. (2025). Species- and age-dependent prenyllipid accumulation in Hypericum species\u2019 leaves. Plants, 14.","DOI":"10.3390\/plants14142239"},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Lazdi\u0146a, D., Mi\u0161ina, I., Dukurs, K., and G\u00f3rna\u015b, P. (2026). Taxonomy\u2014Dependent seed tocochromanol composition in the Rutaceae family: Application of sustainable approach for their extraction. Plants, 15.","DOI":"10.3390\/plants15030455"},{"key":"ref_24","first-page":"1","article-title":"Taxonomy and chemotaxonomy of the genus Hypericum","volume":"5","author":"Crockett","year":"2011","journal-title":"Med. Aromat. Plant Sci. Biotechnol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"108893","DOI":"10.1016\/j.jfca.2026.108893","article-title":"Seed tocochromanol-based chemotaxonomy of Euroasian grapevine (Vitaceae) species","volume":"150","author":"Dukurs","year":"2026","journal-title":"J. Food Compos. Anal."},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Lazdi\u0146a, D., Mi\u0161ina, I., Dukurs, K., and G\u00f3rna\u015b, P. (2026). Tocotrienol dominance in Celastraceae family species\u2019 seeds: Phylogenetic patterns. Appl. Sci., 16.","DOI":"10.3390\/app16031521"},{"key":"ref_27","doi-asserted-by":"crossref","unstructured":"Lazdi\u0146a, D., Mi\u0161ina, I., Dukurs, K., and G\u00f3rna\u015b, P. (2026). Screening of tocopherol and tocotrienol diversity in Cornus species seeds using a sustainable extraction protocol. Molecules, 31.","DOI":"10.3390\/molecules31030519"},{"key":"ref_28","doi-asserted-by":"crossref","unstructured":"Lazdi\u0146a, D., Mi\u0161ina, I., Dukurs, K., and G\u00f3rna\u015b, P. (2026). Tocotrienol-dominated profiles in Ilex genus (Aquifoliaceae) seeds and their relationship to plant phylogeny. Diversity, 18.","DOI":"10.3390\/d18020091"},{"key":"ref_29","doi-asserted-by":"crossref","unstructured":"Ortiz-Viedma, J., Bastias-Montes, J.M., Char, C., Vega, C., Quintriqueo, A., Gall\u00f3n-Bedoya, M., Flores, M., Aguilera, J.M., Miranda, J.M., and Barros-Vel\u00e1zquez, J. (2023). Sequential biorefining of bioactive compounds of high functional value from calafate pomace (Berberis microphylla) using supercritical CO2 and pressurized liquids. Antioxidants, 12.","DOI":"10.3390\/antiox12020323"},{"key":"ref_30","first-page":"100950","article-title":"Valorization of extracts from maqui (Aristotelia chilensis) and calafate (Berberis microphylla) biowaste blends by supercritical fluid and pressurized liquid extraction","volume":"15","year":"2024","journal-title":"J. Agric. Food Res."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"S2914","DOI":"10.1080\/10942912.2017.1382509","article-title":"Antioxidant activity of Berberis integerrima seed oil as a natural antioxidant on the oxidative stability of soybean oil","volume":"20","author":"Tavakoli","year":"2017","journal-title":"Int. J. Food Prop."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"8","DOI":"10.14302\/issn.2379-7835.ijn-14-478","article-title":"Physicochemical and fatty acids composition of Barberry integerrima seed","volume":"1","author":"Tavakoli","year":"2016","journal-title":"Int. J. Nutr."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"6560","DOI":"10.3390\/molecules27196560","article-title":"Free and esterified tocopherols, tocotrienols and other extractable and non-extractable tocochromanol-related molecules: Compendium of knowledge, future perspectives and recommendations for chromatographic techniques, tools, and approaches used for tocochromanol determination","volume":"27","author":"Siger","year":"2022","journal-title":"Molecules"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"113107","DOI":"10.1016\/j.scienta.2024.113107","article-title":"Cranberry (Vaccinium macrocarpon Aiton) seeds: An exceptional source of tocotrienols","volume":"331","author":"Sipeniece","year":"2024","journal-title":"Sci. Hortic."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"140913","DOI":"10.1016\/j.foodchem.2024.140913","article-title":"Simultaneous extraction of tocochromanols and flavan-3-ols from the grape seeds: Analytical and industrial aspects","volume":"462","author":"Perkons","year":"2025","journal-title":"Food Chem."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"120321","DOI":"10.1016\/j.indcrop.2024.120321","article-title":"Tocopherol and tocotrienol homologue recovery from Hypericum perforatum L. and extraction residues after hydroethanolic extraction","volume":"224","year":"2025","journal-title":"Ind. Crops Prod."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"7657","DOI":"10.1038\/s41598-018-25997-2","article-title":"Occurrence of tocopheryl fatty acid esters in vegetables and their non-digestibility by artificial digestion juices","volume":"8","author":"Darwisch","year":"2018","journal-title":"Sci. Rep."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1094\/CCHEM-84-1-0056","article-title":"Oat tocols: Saponification vs. direct extraction and analysis in high-oil genotypes","volume":"84","author":"Peterson","year":"2007","journal-title":"Cereal Chem."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.chroma.2013.03.036","article-title":"Combination of saponification and dispersive liquid\u2013liquid microextraction for the determination of tocopherols and tocotrienols in cereals by reversed-phase high-performance liquid chromatography","volume":"1300","author":"Shammugasamy","year":"2013","journal-title":"J. Chromatogr. A"},{"key":"ref_40","doi-asserted-by":"crossref","unstructured":"Kut, K., Tama, A., Furdak, P., Bartosz, G., and Sadowska-Bartosz, I. (2024). Generation of hydrogen peroxide and phenolic content in plant-material-based beverages and spices. Processes, 12.","DOI":"10.3390\/pr12010166"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1002\/ejlt.200900058","article-title":"Tocopherols and tocotrienols in grape seeds from 14 cultivars grown in Korea","volume":"111","author":"Wie","year":"2009","journal-title":"Eur. J. Lipid Sci. Technol."},{"key":"ref_42","doi-asserted-by":"crossref","unstructured":"Fern\u00e1ndez-Mar\u00edn, B., M\u00edguez, F., M\u00e9ndez-Fern\u00e1ndez, L., Agut, A., Becerril, J.M., Garc\u00eda-Plazaola, J.I., Kranner, I., and Colville, L. (2017). Seed carotenoid and tocochromanol composition of wild Fabaceae species is shaped by phylogeny and ecological factors. Front. Plant Sci., 8.","DOI":"10.3389\/fpls.2017.01428"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/s11130-018-0706-x","article-title":"Selected uncommon legumes as a source of essential fatty acids, tocopherols, tocotrienols, sterols, carotenoids, and squalene","volume":"74","author":"Czubinski","year":"2019","journal-title":"Plant Foods Hum. Nutr."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"2078","DOI":"10.1002\/jsfa.9400","article-title":"Diversity of oil yield, fatty acids, tocopherols, tocotrienols, and sterols in the seeds of 19 interspecific grapes crosses","volume":"99","author":"Grygier","year":"2019","journal-title":"J. Sci. Food Agric."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1016\/j.molp.2022.01.015","article-title":"A well-supported nuclear phylogeny of Poaceae and implications for the evolution of C4 photosynthesis","volume":"15","author":"Huang","year":"2022","journal-title":"Mol. Plant"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"e11","DOI":"10.1093\/jxb\/erx005","article-title":"A portrait of the C4 photosynthetic family on the 50th anniversary of its discovery: Species number, evolutionary lineages, and Hall of Fame","volume":"68","author":"Sage","year":"2017","journal-title":"J. Exp. Bot."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1007\/s11738-021-03350-x","article-title":"Tocopherol as plant protector: An overview of tocopherol biosynthesis enzymes and their role as antioxidant and signaling molecules","volume":"44","author":"Ali","year":"2022","journal-title":"Acta Physiol. Plant."},{"key":"ref_48","doi-asserted-by":"crossref","unstructured":"Hsieh, C.-L., Yu, C.-C., Huang, Y.-L., and Chung, K.-F. (2022). Mahonia vs. Berberis unloaded: Generic delimitation and infrafamilial classification of Berberidaceae based on plastid phylogenomics. Front. Plant Sci., 12.","DOI":"10.3389\/fpls.2021.720171"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"148959","DOI":"10.1016\/j.gene.2024.148959","article-title":"Chloroplast genome evolution of Berberis (Berberidaceae): Implications for phylogeny and metabarcoding","volume":"933","author":"Li","year":"2025","journal-title":"Gene"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.phytochem.2013.07.008","article-title":"Vitamin E analyses in seeds reveal a dominant presence of tocotrienols over tocopherols in the Arecaceae family","volume":"95","author":"Siles","year":"2013","journal-title":"Phytochemistry"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1016\/S0031-9422(98)00641-4","article-title":"Chemotaxonomic value of tocopherols in Brassicaceae","volume":"50","author":"Goffman","year":"1999","journal-title":"Phytochemistry"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/S0031-9422(99)00203-4","article-title":"Chemotaxonomic significance of fatty acids and tocopherols in Boraginaceae","volume":"52","author":"Velasco","year":"1999","journal-title":"Phytochemistry"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"14015","DOI":"10.1038\/hortres.2014.15","article-title":"Genetic and phenological variation of tocochromanol (vitamin E) content in wild (Daucus carota L. var. carota) and domesticated carrot (D. carota L. var. sativa)","volume":"1","author":"Luby","year":"2014","journal-title":"Hortic. Res."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"130638","DOI":"10.1016\/j.foodchem.2021.130638","article-title":"Natural diversity in the carotene, tocochromanol and fatty acid composition of crude palm oil","volume":"365","author":"Morcillo","year":"2021","journal-title":"Food Chem."},{"key":"ref_55","doi-asserted-by":"crossref","unstructured":"Georgiadou, E.C., Goulas, V., Ntourou, T., Manganaris, G.A., Kalaitzis, P., and Fotopoulos, V. (2016). Regulation of on-tree vitamin E biosynthesis in olive fruit during successive growing years: The impact of fruit development and environmental cues. Front. Plant Sci., 7.","DOI":"10.3389\/fpls.2016.01656"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1016\/j.plaphy.2006.10.010","article-title":"Accumulation of tocopherols and tocotrienols during seed development of grape (Vitis vinifera L. cv. Albert Lavall\u00e9e)","volume":"44","author":"Horvath","year":"2006","journal-title":"Plant Physiol. Biochem."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"1900386","DOI":"10.1002\/ejlt.201900386","article-title":"Associations between oil yield and profile of fatty acids, sterols, squalene, carotenoids, and tocopherols in seed oil of selected Japanese quince genotypes during fruit development","volume":"122","author":"Sipeniece","year":"2020","journal-title":"Eur. J. Lipid Sci. Technol."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"6058","DOI":"10.1021\/jf0200016","article-title":"Warm temperatures or drought during seed maturation increase free \u03b1-tocopherol in seeds of soybean (Glycine max [L.] Merr.)","volume":"50","author":"Britz","year":"2002","journal-title":"J. Agric. Food Chem."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"13081","DOI":"10.1021\/jf2037714","article-title":"Effects of high temperature stress at different development stages on soybean isoflavone and tocopherol concentrations","volume":"59","author":"Chennupati","year":"2011","journal-title":"J. Agric. Food Chem."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.plantsci.2015.12.005","article-title":"Specific roles of tocopherols and tocotrienols in seed longevity and germination tolerance to abiotic stress in transgenic rice","volume":"244","author":"Chen","year":"2016","journal-title":"Plant Sci."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"3263","DOI":"10.1002\/jsfa.8829","article-title":"Genotype\u00d7 environment interaction on tocochromanol and plastochromanol-8 content in seeds of doubled haploids obtained from F1 hybrid black\u00d7 yellow seeds of winter oilseed rape (Brassica napus L.)","volume":"98","author":"Siger","year":"2018","journal-title":"J. Sci. Food Agric."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"105511","DOI":"10.1016\/j.jfca.2023.105511","article-title":"The effect of the genotype-environment interaction on the concentration of carotenoids, tocochromanol, and phenolic compounds in seeds of Lupinus angustifolius breeding lines","volume":"123","author":"Siger","year":"2023","journal-title":"J. Food Compos. Anal."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"2079","DOI":"10.1007\/s00217-020-03557-1","article-title":"Influence of variety and growing location on carotenoid and vitamin E contents of 184 different durum wheat varieties (Triticum turgidum ssp. durum) in Germany","volume":"246","author":"Groth","year":"2020","journal-title":"Eur. Food Res. Technol."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"103733","DOI":"10.1016\/j.jcs.2023.103733","article-title":"Tocol content in oat varieties grown under different environmental conditions and farming systems","volume":"113","author":"Kotikova","year":"2023","journal-title":"J. Cereal Sci."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"2845","DOI":"10.1021\/acs.jafc.0c07571","article-title":"Location and variety but not phosphate starter fertilization influence the profiles of fatty acids, carotenoids, and tocochromanols in kernels of modern corn (Zea mays L.) hybrids cultivated in Germany","volume":"69","author":"Lux","year":"2021","journal-title":"J. Agric. Food Chem."},{"key":"ref_66","doi-asserted-by":"crossref","unstructured":"Delfine, S., Fratianni, A., D\u2019Agostino, A., and Panfili, G. (2022). Influence of drought stress on physiological responses and bioactive compounds in chicory (Cichorium intybus L.): Opportunity for a sustainable agriculture. Foods, 11.","DOI":"10.3390\/foods11223725"},{"key":"ref_67","doi-asserted-by":"crossref","unstructured":"Mi\u0137elsone, I., Sipeniece, E., Mi\u0161ina, I., Bondarenko, E., Segli\u0146a, D., and G\u00f3rna\u015b, P. (2025). Impact of soil on biomass yield and accumulation of lipophilic secondary metabolites in four Hypericum species. Agriculture, 15.","DOI":"10.3390\/agriculture15050526"},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"9465","DOI":"10.1021\/acs.jafc.6b03902","article-title":"Factors affecting tocopherol concentrations in soybean seeds","volume":"64","author":"Carrera","year":"2016","journal-title":"J. Agric. Food Chem."},{"key":"ref_69","doi-asserted-by":"crossref","unstructured":"Rosado, M.J., Marques, G., Rencoret, J., Guti\u00e9rrez, A., Bausch, F., Rosenau, T., Potthast, A., and Del R\u00edo, J.C. (2022). Chemical composition of the lipophilic compounds from the rind and pith of papyrus (Cyperus papyrus L.) stems. Front. Plant Sci., 13.","DOI":"10.3389\/fpls.2022.1097866"},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1016\/S0031-9422(00)89825-8","article-title":"Tocopheryl esters from Nymphea alba and Nuphar luteum","volume":"36","author":"Klink","year":"1994","journal-title":"Phytochemistry"},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1021\/jf304441j","article-title":"Identification of tocopherols, tocotrienols, and their fatty acid esters in residues and distillates of structured lipids purified by short-path distillation","volume":"61","author":"Zou","year":"2013","journal-title":"J. Agric. Food Chem."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"1600027","DOI":"10.1002\/ejlt.201600027","article-title":"Influence of deodorization temperature on formation of tocopherol esters and fatty acids polymers in vegetable oil","volume":"119","author":"Kreps","year":"2017","journal-title":"Eur. J. Lipid Sci. Technol."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1002\/ejlt.201500218","article-title":"Synthesis and analysis of tocopheryl quinone and tocopherol esters with fatty acids in heated sunflower oil","volume":"118","author":"Kreps","year":"2016","journal-title":"Eur. J. Lipid Sci. Technol."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"H762","DOI":"10.1111\/1750-3841.13222","article-title":"Changes in the bioactive compounds content of soybean as a function of grain moisture content and temperature during long-term storage","volume":"81","author":"Ziegler","year":"2016","journal-title":"J. Food Sci."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1021\/jf9912755","article-title":"Changes in tocopherol and plastochromanol-8 contents in seeds and oil of oilseed rape (Brassica napus L.) during storage as influenced by temperature and air oxygen","volume":"48","author":"Goffman","year":"2000","journal-title":"J. Agric. Food Chem."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1017\/S0960258522000101","article-title":"Antioxidant depletion during seed storage under ambient conditions","volume":"32","author":"Stegner","year":"2022","journal-title":"Seed Sci. Res."},{"key":"ref_77","doi-asserted-by":"crossref","unstructured":"M\u00e8ne-Saffran\u00e9, L. (2018). Vitamin E biosynthesis and its regulation in plants. Antioxidants, 7.","DOI":"10.3390\/antiox7010002"}],"container-title":["Plants"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2223-7747\/15\/5\/676\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T05:18:04Z","timestamp":1772083084000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2223-7747\/15\/5\/676"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,24]]},"references-count":77,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2026,3]]}},"alternative-id":["plants15050676"],"URL":"https:\/\/doi.org\/10.3390\/plants15050676","relation":{},"ISSN":["2223-7747"],"issn-type":[{"value":"2223-7747","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,24]]}}}