{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T05:04:55Z","timestamp":1775624695803,"version":"3.50.1"},"reference-count":53,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T00:00:00Z","timestamp":1775174400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Plants"],"abstract":"<jats:p>X. fastidiosa subsp. pauca (Xfp) is the etiological agent of \u201cOlive Quick Decline Syndrome\u201d (OQDS). Cellina di Nard\u00f2 (Olea europaea L., Oleaceae), one of the major Salento cultivars, is highly susceptible to Xfp, usually showing acute symptoms after infection. NuovOlivo\u00ae a plant-derived formulation made with vegetal oils and water infusion from multi botanical species has been reported as effective against OQDS in plants affected by Xfp. A non-targeted 1H NMR (Nuclear Magnetic Resonance) fingerprinting approach, with unsupervised and supervised analysis, was applied to observe the possible changes in the metabolic profile in leaf samples of cultivars Cellina di Nard\u00f2 naturally affected by Xfp treated with NuovOlivo\u00ae compared to untreated plants. The major differences were observed for the content of quinic acid, malate, mannitol, glucose, oleuropein, and aldehyde derivatives in treated compared to untreated samples. The resulting data indicated a season-dependent plant response to both disease and treatment. Moreover, the overall differences observed between the two investigated years, suggest a general decrease in the differences for the discriminating metabolites over time. The protocol NuovOlivo\u00ae was demonstrated to promote changes in the metabolic profile of olive leaves, suggesting a possible role of this treatment, integrated with good agricultural practices, against Xfp and OQDS.<\/jats:p>","DOI":"10.3390\/plants15071109","type":"journal-article","created":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T00:19:32Z","timestamp":1775434772000},"page":"1109","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["1H NMR Approach for Evaluating the Effects of a Natural Detergent on Olive Trees Infected by Xylella fastidiosa subsp. pauca"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-9506-0966","authenticated-orcid":false,"given":"Miriana Carla","family":"Fazzi","sequence":"first","affiliation":[{"name":"Department of Biological and Environmental Sciences and Technology, University of Salento, 73100 Lecce, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0085-8539","authenticated-orcid":false,"given":"Chiara Roberta","family":"Girelli","sequence":"additional","affiliation":[{"name":"Department of Biological and Environmental Sciences and Technology, University of Salento, 73100 Lecce, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3073-5772","authenticated-orcid":false,"given":"Francesco Paolo","family":"Fanizzi","sequence":"additional","affiliation":[{"name":"Department of Biological and Environmental Sciences and Technology, University of Salento, 73100 Lecce, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2026,4,3]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1525\/gfc.2020.20.2.55","article-title":"Xylella fastidiosa and the Olive Oil Crisis in Puglia","volume":"20","author":"Ipsen","year":"2020","journal-title":"Gastronomica"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Scortichini, M., Manetti, G., Brunetti, A., Lumia, V., Sciarroni, L., and Pilotti, M. 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