{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T05:27:08Z","timestamp":1786685228560,"version":"build-2736575974"},"reference-count":25,"publisher":"MDPI AG","issue":"16","license":[{"start":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T00:00:00Z","timestamp":1786492800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100016107","name":"Science and Technology Department of Tibet Autonomous Region","doi-asserted-by":"crossref","award":["XZ202301ZY0009N"],"award-info":[{"award-number":["XZ202301ZY0009N"]}],"id":[{"id":"10.13039\/501100016107","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32570381"],"award-info":[{"award-number":["32570381"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["30971558"],"award-info":[{"award-number":["30971558"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["91631109"],"award-info":[{"award-number":["91631109"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"award":["32570381"],"award-info":[{"award-number":["32570381"]}],"id":[{"id":"https:\/\/ror.org\/01h0zpd94","id-type":"ROR","asserted-by":"publisher"}]},{"award":["30971558"],"award-info":[{"award-number":["30971558"]}],"id":[{"id":"https:\/\/ror.org\/01h0zpd94","id-type":"ROR","asserted-by":"publisher"}]},{"award":["91631109"],"award-info":[{"award-number":["91631109"]}],"id":[{"id":"https:\/\/ror.org\/01h0zpd94","id-type":"ROR","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Plants"],"abstract":"<jats:p>Bryophytes possess a gene family repertoire substantially larger than vascular plants, yet the functional evolution of their transcription factors remains poorly understood. We conducted a nested analysis across 144 bryophyte genomes, cataloging 58 transcription factor families and deeply characterizing the C2H2 zinc-finger protein family. We identified 8246 C2H2 zinc-finger genes classified into four structural types based on zinc-finger architecture. Domain-level scanning of 11,565 zinc fingers revised Z-type frequency from ~20% to 4.2%. The plant-specific Q-type was most prevalent in mosses and least prevalent in liverworts, with the major Q-type radiation occurring in seed plants. C2H2 zinc-finger gene expansion in mosses was driven by whole-genome duplication, and gene count correlated with genome size. Through re-analysis of publicly available RNA-seq datasets, cross-species expression profiling showed that mosses mobilized 23\u201328% of their C2H2 zinc-finger repertoires under dehydration, whereas the liverwort Marchantia polymorpha showed no significant response to osmotic stress and only a weak, transient response to salt. Notably, the aluminum-tolerance regulator STOP1 was downregulated under dehydration. Together, these results suggest a marked divergence in stress-responsive C2H2-ZFP deployment between mosses and liverworts, although the underlying mechanisms remain to be validated functionally.<\/jats:p>","DOI":"10.3390\/plants15162452","type":"journal-article","created":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T12:53:48Z","timestamp":1786539228000},"page":"2452","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Bryophyte Transcription Factor Landscape Reveals Lineage-Specific Zinc-Finger Protein Evolution and Differential Stress Mobilization Between Mosses and Liverworts"],"prefix":"10.3390","volume":"15","author":[{"given":"Xiangxi","family":"He","sequence":"first","affiliation":[{"name":"Key Laboratory of Plant Gene Resources and Biotechnology for Carbon Reduction and Environmental Improvement, Beijing Municipal Government, College of Life Sciences, Capital Normal University, Beijing 100048, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-2326-9079","authenticated-orcid":false,"given":"Fengjun","family":"Leng","sequence":"additional","affiliation":[{"name":"Key Laboratory of Plant Gene Resources and Biotechnology for Carbon Reduction and Environmental Improvement, Beijing Municipal Government, College of Life Sciences, Capital Normal University, Beijing 100048, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuyi","family":"Yan","sequence":"additional","affiliation":[{"name":"Key Laboratory of Plant Gene Resources and Biotechnology for Carbon Reduction and Environmental Improvement, Beijing Municipal Government, College of Life Sciences, Capital Normal University, Beijing 100048, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-7665-3542","authenticated-orcid":false,"given":"Yong","family":"Hu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Plant Gene Resources and Biotechnology for Carbon Reduction and Environmental Improvement, Beijing Municipal Government, College of Life Sciences, Capital Normal University, Beijing 100048, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yikun","family":"He","sequence":"additional","affiliation":[{"name":"Key Laboratory of Plant Gene Resources and Biotechnology for Carbon Reduction and Environmental Improvement, Beijing Municipal Government, College of Life Sciences, Capital Normal University, Beijing 100048, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,8,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2105","DOI":"10.1126\/science.290.5499.2105","article-title":"Arabidopsis transcription factors: Genome-wide comparative analysis among eukaryotes","volume":"290","author":"Riechmann","year":"2000","journal-title":"Science"},{"key":"ref_2","first-page":"E4858","article-title":"Transcription factor evolution in eukaryotes and the assembly of the regulatory toolkit in multicellular lineages","volume":"110","author":"Torruella","year":"2013","journal-title":"Proc. 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