{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T09:28:09Z","timestamp":1786958889343,"version":"build-2736575974"},"reference-count":52,"publisher":"MDPI AG","issue":"16","license":[{"start":{"date-parts":[[2026,8,16]],"date-time":"2026-08-16T00:00:00Z","timestamp":1786838400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100009096","name":"F\u0131rat University","doi-asserted-by":"publisher","award":["MF.22.46"],"award-info":[{"award-number":["MF.22.46"]}],"id":[{"id":"10.13039\/100009096","id-type":"DOI","asserted-by":"publisher"}]},{"award":["MF.22.46"],"award-info":[{"award-number":["MF.22.46"]}],"id":[{"id":"https:\/\/ror.org\/05teb7b63","id-type":"ROR","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Plants"],"abstract":"<jats:p>Indoor air pollution caused by volatile organic compounds (VOCs) is a major environmental and public health concern. Ethanol is a common indoor VOC released from cleaning products, disinfectants, and industrial activities. This study evaluated the capacity of Ficus elastica Roxb. to remove airborne ethanol under controlled chamber conditions. Response Surface Methodology was applied to optimise the effects of initial ethanol concentration, relative humidity, and exposure time on removal efficiency. The model predicted a maximum removal efficiency of 97.16%, which was experimentally validated with an average efficiency of 96.2%, confirming the model\u2019s reliability. Analysis of variance identified exposure time as the most influential factor affecting ethanol removal. Desorption experiments showed only limited and transient ethanol re-emission, indicating that ethanol was not merely adsorbed but also partially metabolised by the plant. Scanning electron microscopy revealed structural changes in stomatal morphology after prolonged exposure. Biochemical analyses demonstrated increased total phenolic content, flavonoid content, and antioxidant capacity, whereas a moderate decline in total chlorophyll reflected physiological stress accompanied by enhanced defence responses, indicating adaptive tolerance to prolonged ethanol exposure. These findings demonstrate the potential of F. elastica as an effective and sustainable botanical biofiltration system for improving indoor air quality.<\/jats:p>","DOI":"10.3390\/plants15162484","type":"journal-article","created":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T08:05:41Z","timestamp":1786953941000},"page":"2484","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Removal of Ethanol from Indoor Air by Ficus elastica Roxb.: Process Optimisation and Post-Removal Desorption Dynamics"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4204-8638","authenticated-orcid":false,"given":"Abayhan","family":"Buran","sequence":"first","affiliation":[{"name":"Bioengineering Department, Faculty of Engineering, F\u0131rat University, Elaz\u0131\u011f 23119, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aykut","family":"Topdemir","sequence":"additional","affiliation":[{"name":"Bioengineering Department, Faculty of Engineering, F\u0131rat University, Elaz\u0131\u011f 23119, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,8,16]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1038\/sj.jea.7500309","article-title":"Variability of Environmental Exposures to Volatile Organic Compounds","volume":"14","author":"Rappaport","year":"2004","journal-title":"J. Expo. Sci. Environ. Epidemiol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"2205458","DOI":"10.1002\/advs.202205458","article-title":"Unique Photoactivated Time-resolved Response in 2D GeS for Selective Detection of Volatile Organic Compounds","volume":"10","author":"Mohammadzadeh","year":"2023","journal-title":"Adv. Sci."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1186\/s12940-018-0410-1","article-title":"Exposure to Volatile Organic Compounds and Airway Inflammation","volume":"17","author":"Kwon","year":"2018","journal-title":"Environ. Health"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1111\/ina.12667","article-title":"Volatile Organic Compounds in 169 Energy-efficient Dwellings in Switzerland","volume":"30","author":"Shen","year":"2020","journal-title":"Indoor Air"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"882","DOI":"10.3155\/1047-3289.59.7.882","article-title":"Investigation of the Treatability of the Primary Indoor Volatile Organic Compounds on Activated Carbon Fiber Cloths at Typical Indoor Concentrations","volume":"59","author":"Meng","year":"2009","journal-title":"J. Air Waste Manag. Assoc."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1183\/09059180.00000714","article-title":"Volatile Organic Compounds and Risk of Asthma and Allergy: A Systematic Review","volume":"24","author":"Nurmatov","year":"2015","journal-title":"Eur. Respir. Rev."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1183\/09031936.00153509","article-title":"Exposure to Volatile Organic Compounds and Loss of Pulmonary Function in the Elderly","volume":"36","author":"Yoon","year":"2010","journal-title":"Eur. Respir. J."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1598","DOI":"10.1016\/j.rmed.2013.07.015","article-title":"Higher Prevalence of Breathlessness in Elderly Exposed to Indoor Aldehydes and VOCs in a Representative Sample of French Dwellings","volume":"107","author":"Bentayeb","year":"2013","journal-title":"Respir. Med."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Cheng, W., Chen, Y., and Shih, S. (2023). Volatile Organic Compound Emissions from Indoor Fragrance Diffusers. Atmosphere, 14.","DOI":"10.3390\/atmos14061012"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"517","DOI":"10.4168\/aair.2014.6.6.517","article-title":"Relationship between Indoor Air Pollutant Levels and Residential Environment in Children with Atopic Dermatitis","volume":"6","author":"Lee","year":"2014","journal-title":"Allergy Asthma Immunol. Res."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"e202100486","DOI":"10.1002\/cplu.202100486","article-title":"Renewable Activated Carbon Filters Bearing Photocatalytic Particles for Volatile Organic Compound Removal","volume":"87","author":"Kim","year":"2022","journal-title":"Chempluschem"},{"key":"ref_12","first-page":"3","article-title":"An Emerging Paradox: Toward a Better Understanding of the Potential Benefits and Adversity of Microbe Exposures in the Indoor Environment","volume":"27","author":"Hernandez","year":"2016","journal-title":"Indoor Air"},{"key":"ref_13","unstructured":"Centers for Disease Control and Prevention (CDC) (2026, August 04). National Institute for Occupational Safety and Health (NIOSH) NIOSH Pocket Guide to Chemical Hazards\u2014Ethyl Alcohol (CAS 64-17-5), Available online: https:\/\/www.cdc.gov\/niosh\/npg\/npgd0262.html."},{"key":"ref_14","first-page":"959070","article-title":"Short Communication: Is Ethanol-Based Hand Sanitizer Involved in Acute Pancreatitis after Excessive Disinfection?\u2014An Evaluation with the Use of PBPK Model","volume":"2012","author":"Artigou","year":"2012","journal-title":"J. Toxicol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1177\/1082013217735951","article-title":"Delaying Microbial Proliferation in Freshly Peeled Shallots by Active Packaging Incorporating Ethanol Vapour-Controlled Release Sachets and Low Storage Temperature","volume":"24","author":"Utto","year":"2017","journal-title":"Food Sci. Technol. Int."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"230","DOI":"10.21273\/HORTSCI.49.2.230","article-title":"Volatile Toluene and Xylene Removal Efficiency of Foliage Plants as Affected by Top to Root Zone Size","volume":"49","author":"Jung","year":"2014","journal-title":"HortScience"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1111\/ina.12473","article-title":"Biofiltration of Airborne VOCs with Green Wall Systems\u2014Microbial and Chemical Dynamics","volume":"28","author":"Mikkonen","year":"2018","journal-title":"Indoor Air"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"445","DOI":"10.11628\/ksppe.2018.21.6.445","article-title":"Applied Horticultural Biotechnology for the Mitigation of Indoor Air Pollution","volume":"21","author":"Torpy","year":"2018","journal-title":"J. People Plants Environ."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/s11869-017-0518-4","article-title":"Testing the Single-Pass VOC Removal Efficiency of an Active Green Wall Using Methyl Ethyl Ketone (MEK)","volume":"11","author":"Torpy","year":"2017","journal-title":"Air Qual. Atmos. Health"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1016\/j.chemosphere.2018.06.048","article-title":"Towards Practical Indoor Air Phytoremediation: A Review","volume":"208","author":"Pettit","year":"2018","journal-title":"Chemosphere"},{"key":"ref_21","unstructured":"Rausch, K.D., and Belyea, R.L. (2005). Coproducts from Bioprocessing of Corn. Proceedings of the American Society of Agricultural and Biological Engineers, ASAE."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"26","DOI":"10.24425\/aep.2021.136445","article-title":"Removal of Cyclohexane and Ethanol from Air in Biotrickling Filters Inoculated with Candida Albicans and Candida Subhashii","volume":"47","author":"Rybarczyk","year":"2021","journal-title":"Arch. Environ. Prot."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"46235","DOI":"10.1038\/srep46235","article-title":"Dependence of Plant Uptake and Diffusion of Polycyclic Aromatic Hydrocarbons on the Leaf Surface Morphology and Micro-Structures of Cuticular Waxes","volume":"7","author":"Li","year":"2017","journal-title":"Sci. Rep."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1007\/s11270-025-08504-y","article-title":"Evaluating the Benzene Removal Efficiency of Ficus Elastica in Closed-Chamber Conditions","volume":"236","author":"Sharma","year":"2025","journal-title":"Water Air Soil Pollut."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"9963512","DOI":"10.1155\/ina\/9963512","article-title":"Removal of Toluene From Indoor Air Under Optimal Conditions Using Ficus Elastica Roxb. Plants Obtained by Micropropagation","volume":"2026","author":"Buran","year":"2026","journal-title":"Indoor Air"},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Fahad, S., Bajwa, A.A., Nazir, U., Anjum, S.A., Farooq, A., Zohaib, A., Sadia, S., Nasim, W., Adkins, S., and Saud, S. (2017). Crop Production under Drought and Heat Stress: Plant Responses and Management Options. Front. Plant Sci., 8.","DOI":"10.3389\/fpls.2017.01147"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1021\/es071552l","article-title":"Direct Measurement of VOC Diffusivities in Tree Tissues: Impacts on Tree-Based Phytoremediation and Plant Contamination","volume":"42","author":"Baduru","year":"2008","journal-title":"Environ. Sci. Technol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2136\/vzj2012.0081","article-title":"Subsurface and Plant Contamination During Natural Attenuation and Phytoremediation of Silt Loam Contaminated with Chlorinated Organic Compounds","volume":"12","author":"Cho","year":"2013","journal-title":"Vadose Zone J."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"595","DOI":"10.4236\/jsea.2012.58068","article-title":"Comparison of Radial Basis Function Neural Network and Response Surface Methodology for Predicting Performance of Biofilter Treating Toluene","volume":"05","author":"Deshmukh","year":"2012","journal-title":"J. Softw. Eng. Appl."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"765","DOI":"10.21273\/HORTSCI.50.5.765","article-title":"Phytoremediation of Indoor Air","volume":"50","author":"Thomas","year":"2015","journal-title":"HortScience"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"126875","DOI":"10.1016\/j.jhazmat.2021.126875","article-title":"Modelling Botanical Biofiltration of Indoor Air Streams Contaminated by Volatile Organic Compounds","volume":"422","author":"Masi","year":"2022","journal-title":"J. Hazard. Mater."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1038\/s41370-019-0175-9","article-title":"Potted Plants Do Not Improve Indoor Air Quality: A Review and Analysis of Reported VOC Removal Efficiencies","volume":"30","author":"Cummings","year":"2019","journal-title":"J. Expo. Sci. Environ. Epidemiol."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/s11270-006-9124-z","article-title":"The Potted-Plant Microcosm Substantially Reduces Indoor Air VOC Pollution: I. Office Field-Study","volume":"175","author":"Wood","year":"2006","journal-title":"Water Air Soil Pollut."},{"key":"ref_34","first-page":"476","article-title":"Effect of Bacterial Population from Rhizosphere of Various Foliage Plants on Removal of Indoor Volatile Organic Compounds","volume":"28","author":"Chun","year":"2010","journal-title":"Korean J. Hortic. Sci."},{"key":"ref_35","first-page":"45","article-title":"A Research on the Ability of Absorbing Formaldehyde Among Five Species of Indoor Ornamentals","volume":"34","author":"Xiong","year":"2009","journal-title":"Environ. Sci. Manag."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1111\/j.1600-0668.2005.00421.x","article-title":"Volatile Organic Compound (VOC) Adsorption on Material: Influence of Gas Phase Concentration, Relative Humidity and VOC Type","volume":"16","author":"Huang","year":"2006","journal-title":"Indoor Air"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"171","DOI":"10.4491\/eer.2018.444","article-title":"Excellent Toluene Removal via Adsorption by Honeycomb Adsorbents under High Temperature and Humidity Conditions","volume":"25","author":"Cho","year":"2019","journal-title":"Environ. Eng. Res."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1007\/s11240-024-02923-1","article-title":"Challenges and Insights in the Acclimatization Step of Micropropagated Woody Plants","volume":"159","author":"Grzelak","year":"2024","journal-title":"Plant Cell Tissue Organ Cult. (PCTOC)"},{"key":"ref_39","doi-asserted-by":"crossref","unstructured":"Acosta-Motos, J.R., Noguera-Vera, L., Barba-Esp\u00edn, G., Piqueras, A., and Hern\u00e1ndez, J.A. (2019). Antioxidant Metabolism and Chlorophyll Fluorescence during the Acclimatisation to Ex Vitro Conditions of Micropropagated Stevia Rebaudiana Bertoni Plants. Antioxidants, 8.","DOI":"10.3390\/antiox8120615"},{"key":"ref_40","doi-asserted-by":"crossref","unstructured":"Xie, Y., Lyu, S., Zhang, Y., and Cai, C. (2022). Adsorption and Degradation of Volatile Organic Compounds by Metal\u2013Organic Frameworks (MOFs): A Review. Materials, 15.","DOI":"10.3390\/ma15217727"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.21273\/HORTSCI.44.5.1377","article-title":"Screening Indoor Plants for Volatile Organic Pollutant Removal Efficiency","volume":"44","author":"Yang","year":"2009","journal-title":"Hortscience"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"6149","DOI":"10.1007\/s11356-016-6065-y","article-title":"Removal Ratio of Gaseous Toluene and Xylene Transported from Air to Root Zone via the Stem by Indoor Plants","volume":"23","author":"Kim","year":"2016","journal-title":"Environ. Sci. Pollut. Res."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1007\/s11869-014-0285-4","article-title":"Phytoremediation of Particulate Matter from Indoor Air by Chlorophytum Comosum L. Plants","volume":"8","author":"Bakera","year":"2015","journal-title":"Air Qual. Atmos. Health"},{"key":"ref_44","first-page":"100274","article-title":"An Absorption Model of Volatile Organic Compound by Plant Leaf: The Most Influential Site in the Absorption Pathway","volume":"23","author":"Yamane","year":"2024","journal-title":"Atmos. Environ. X"},{"key":"ref_45","doi-asserted-by":"crossref","unstructured":"Kask, K., Kaurilind, E., Talts, E., K\u00e4nnaste, A., and Niinemets, \u00dc. (2021). Combined Acute Ozone and Water Stress Alters the Quantitative Relationships between O3 Uptake, Photosynthetic Characteristics and Volatile Emissions in Brassica Nigra. Molecules, 26.","DOI":"10.3390\/molecules26113114"},{"key":"ref_46","doi-asserted-by":"crossref","unstructured":"Shin, J., Lee, Y., Hahm, S., Lee, K., and Park, J. (2023). Effects of Exogenous Ethanol Treatment in Nutrient Solution on Growth and Secondary Metabolite Contents of Three Herb Species in an Indoor Vertical Farming System. Plants, 12.","DOI":"10.3390\/plants12223842"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"144","DOI":"10.5344\/ajev.1965.16.3.144","article-title":"Colorimetry of Total Phenolics with Phosphomolybdic Phosphotungstic Acid Reagents","volume":"16","author":"Singleton","year":"1965","journal-title":"Am. J. Enol. Vitic."},{"key":"ref_48","first-page":"315","article-title":"Teneurs En Principaux Flavonoides Des Fleurs de Crataegus Monogyna Jacq et de Crataegus Laevigata (Poiret D. C) En Fonction de La Vegetation","volume":"65","author":"Lamaison","year":"1990","journal-title":"Pharm. Acta Helv."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"1794","DOI":"10.1021\/jf00055a009","article-title":"Evaluation of the Total Antioxidant Activity as a Marker of the Deterioration of Apple Juice on Storage","volume":"43","author":"Miller","year":"1995","journal-title":"J. Agric. Food Chem."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1104\/pp.24.1.1","article-title":"Copper Enzymes in Isolated Chloroplasts Polyphenoloxidase in Beta Vulgaris","volume":"24","author":"Arnon","year":"1949","journal-title":"J. Plant Physiol."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1042\/bst0110591","article-title":"Determination of Total Carotenoids and Chlorophyll a and b of Leaf Extracts in Different Solvents","volume":"11","author":"Lichtenthaler","year":"1983","journal-title":"Biochem. Soc. Trans."},{"key":"ref_52","unstructured":"Buran, A. (2025). Botanik Hava Filtrasyon Sisteminde Mikro\u00e7o\u011falt\u0131m Y\u00f6ntemi ile Elde Edilen Ficus elastica Roxb. Bitkisi Kullan\u0131larak Kapal\u0131 Ortam Havas\u0131ndaki U\u00e7ucu Organik Bile\u015fiklerin (toluen ve etanol) Uzakla\u015ft\u0131r\u0131lmas\u0131. [PhD Thesis, F\u0131rat University]."}],"container-title":["Plants"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2223-7747\/15\/16\/2484\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T08:59:04Z","timestamp":1786957144000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2223-7747\/15\/16\/2484"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,16]]},"references-count":52,"journal-issue":{"issue":"16","published-online":{"date-parts":[[2026,8]]}},"alternative-id":["plants15162484"],"URL":"https:\/\/doi.org\/10.3390\/plants15162484","relation":{},"ISSN":["2223-7747"],"issn-type":[{"value":"2223-7747","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,16]]}}}