{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T15:30:45Z","timestamp":1789659045400,"version":"4.0.1"},"reference-count":90,"publisher":"MDPI AG","issue":"18","license":[{"start":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T00:00:00Z","timestamp":1789344000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Comisi\u00f3n Sectorial de Investigaci\u00f3n Cient\u00edfica, Universidad de la Rep\u00fablica","id":[{"id":"https:\/\/ror.org\/030bbe882","id-type":"ROR","asserted-by":"crossref"}]},{"id":[{"id":"https:\/\/ror.org\/030bbe882","id-type":"ROR","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100024018","name":"Programa de Desarrollo de las Ciencias B\u00e1sicas","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100024018","id-type":"DOI","asserted-by":"crossref"},{"id":"https:\/\/ror.org\/00jkr8r49","id-type":"ROR","asserted-by":"crossref"}]},{"id":[{"id":"https:\/\/ror.org\/00jkr8r49","id-type":"ROR","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Plants"],"abstract":"<jats:p>Botrytis cinerea causes gray mold disease in numerous plant species, including economically important solanaceous crops. To investigate the molecular interaction between B. cinerea and Solanum tuberosum, we performed dual RNA-seq analyses of infected potato leaves at 24 and 72 h post inoculation (hpi). A total of 5932 potato genes were differentially expressed during infection, including genes associated with pathogen perception, hormone signaling, transcriptional regulation, and defense responses to biotic stress. In parallel, 2162 fungal genes showed differential expression, including genes encoding plant cell-wall-degrading enzymes, reactive oxygen species-related proteins, detoxification enzymes, toxins, and candidate secreted effectors. Comparative analyses with an independent transcriptomic dataset from tomato infected with B. cinerea revealed both shared and distinct transcriptional patterns. Similar expression patterns were observed for genes associated with jasmonic acid, ethylene signaling, and stress responses, while differences were found in the induction of genes involved in specialized metabolism. Potato exhibited increased expression of genes associated with germacrene B and \u03b1-farnesene biosynthesis, whereas tomato showed induction of genes related to viridiflorene and costunolide production. In addition, fungal genes involved in botrydial biosynthesis and several secreted virulence-associated enzymes showed stronger induction during tomato infection. These findings provide new insights into the transcriptional responses of potato to B. cinerea infection and the similarities and differences observed in comparison with tomato.<\/jats:p>","DOI":"10.3390\/plants15182815","type":"journal-article","created":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T09:34:01Z","timestamp":1789378441000},"page":"2815","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparative Transcriptomic Analysis of Potato and Tomato Responses to Botrytis cinerea Infection"],"prefix":"10.3390","volume":"15","author":[{"given":"Alfonso","family":"Alvarez","sequence":"first","affiliation":[{"name":"Laboratorio de Fisiolog\u00eda Vegetal, Facultad de Ciencias, Universidad de la Rep\u00fablica, Montevideo 11400, Uruguay"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"conceptualization","vocabulary":"credit"},{"role":"methodology","vocabulary":"credit"},{"role":"investigation","vocabulary":"credit"},{"role":"data-curation","vocabulary":"credit"},{"role":"formal-analysis","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-3716-9862","authenticated-orcid":false,"given":"Ver\u00f3nica","family":"Giacri","sequence":"additional","affiliation":[{"name":"Laboratorio de Fisiolog\u00eda Vegetal, Facultad de Ciencias, Universidad de la Rep\u00fablica, Montevideo 11400, Uruguay"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"investigation","vocabulary":"credit"}]},{"given":"Agustina","family":"Taglioretti","sequence":"additional","affiliation":[{"name":"Laboratorio de Fisiolog\u00eda Vegetal, Facultad de Ciencias, Universidad de la Rep\u00fablica, Montevideo 11400, Uruguay"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"formal-analysis","vocabulary":"credit"}]},{"given":"Guillermo","family":"Reboledo","sequence":"additional","affiliation":[{"name":"Departamento de Biolog\u00eda Molecular, Instituto de Investigaciones Biol\u00f3gicas Clemente Estable, Montevideo 11600, Uruguay"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"formal-analysis","vocabulary":"credit"}]},{"given":"In\u00e9s","family":"Ponce de Le\u00f3n","sequence":"additional","affiliation":[{"name":"Departamento de Biolog\u00eda Molecular, Instituto de Investigaciones Biol\u00f3gicas Clemente Estable, Montevideo 11600, Uruguay"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"conceptualization","vocabulary":"credit"},{"role":"methodology","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"}]},{"given":"Marcos","family":"Montesano","sequence":"additional","affiliation":[{"name":"Laboratorio de Fisiolog\u00eda Vegetal, Facultad de Ciencias, Universidad de la Rep\u00fablica, Montevideo 11400, Uruguay"},{"name":"Departamento de Biolog\u00eda Molecular, Instituto de Investigaciones Biol\u00f3gicas Clemente Estable, Montevideo 11600, Uruguay"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"conceptualization","vocabulary":"credit"},{"role":"methodology","vocabulary":"credit"},{"role":"investigation","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"}]}],"member":"1968","published-online":{"date-parts":[[2026,9,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1111\/nph.14877","article-title":"Multiple strategies for pathogen perception by plant immune receptors","volume":"219","author":"Cesari","year":"2018","journal-title":"New Phytol."},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Ziv, C., Zhao, Z., Gao, Y.G., and Xia, Y. 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