{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T12:15:50Z","timestamp":1789992950145,"version":"4.0.1"},"reference-count":53,"publisher":"MDPI AG","issue":"18","license":[{"start":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T00:00:00Z","timestamp":1789689600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100017513","name":"Sichuan Provincial Science and Technology Program","doi-asserted-by":"publisher","award":["2025ZNSFSC0613"],"award-info":[{"award-number":["2025ZNSFSC0613"]}],"id":[{"id":"10.13039\/100017513","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008363","name":"Sichuan Agricultural University","doi-asserted-by":"publisher","award":["2024ZYTS002"],"award-info":[{"award-number":["2024ZYTS002"]}],"id":[{"id":"10.13039\/501100008363","id-type":"DOI","asserted-by":"publisher"}]},{"award":["2024ZYTS002"],"award-info":[{"award-number":["2024ZYTS002"]}],"id":[{"id":"https:\/\/ror.org\/0388c3403","id-type":"ROR","asserted-by":"publisher"}]},{"name":"Provincial College Student Innovation Training Program","award":["S202610626098"],"award-info":[{"award-number":["S202610626098"]}]},{"DOI":"10.13039\/501100007433","name":"Open Fund Project of the Key Laboratory of Southwest Wildlife and Plant Resources Conservation, Ministry of Education, West China Normal University","doi-asserted-by":"publisher","award":["XNYB25-06"],"award-info":[{"award-number":["XNYB25-06"]}],"id":[{"id":"10.13039\/501100007433","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Plants"],"abstract":"<jats:p>Cadmium (Cd) contamination poses a severe threat to the quality of cultivated land and the safe production of food crops and Chinese herbal medicines in China. The Cd accumulation characteristics of Salvia miltiorrhiza are closely associated with rhizosphere microorganisms; however, the underlying regulatory mechanisms remain elusive. In this study, two S. miltiorrhiza genotypes with high or low Cd accumulation (designated SD and SC, respectively) were employed to comparatively analyze the differences in their rhizosphere bacterial community structures. Combined with reinoculation experiments using bacterial strains tolerant to Cd, we aimed to elucidate the mechanistic roles of rhizosphere bacteria in modulating Cd accumulation in S. miltiorrhiza. 16S rRNA sequencing revealed significant differences in the rhizosphere bacterial community structures between SD and SC, with SC exhibiting higher bacterial diversity and richness, confirming a correlation between rhizosphere microbial community composition and Cd accumulation in S. miltiorrhiza. Functional validation demonstrated that strain Bacillus sp. C4, isolated from SC, significantly reduced Cd accumulation in S. miltiorrhiza roots by 20.35%, whereas strain Bacillus sp. D9, isolated from SD, exerted a contrasting effect, drastically increasing root Cd accumulation by 440.97%. Two distinct rhizobacterial strains were identified with contrasting strategies for modulating Cd partitioning in the soil root continuum of S. miltiorrhiza. Strain C4 acts as a Cd excluder: it elevates rhizosphere pH and adsorbs Cd externally, while decreasing pectin and hemicellulose contents in root cell walls to reduce Cd binding sites, collectively impeding Cd entry into roots. In contrast, strain D9 functions as a Cd accumulator through a dual mechanism. It acidifies the rhizosphere to mobilize sparingly soluble Cd, thereby increasing Cd influx. Concurrently, it upregulates hemicellulose abundance in root cell walls, which amplifies Cd binding capacity and promotes root sequestration. Furthermore, inoculation with strain C4 significantly elevated the contents of bioactive components in S. miltiorrhiza, including cryptotanshinone, tanshinone I, tanshinone IIA, and salvianolic acid B, demonstrating a dual beneficial functionality of concurrent Cd reduction and quality improvement. This study offers functional strains that reduce Cd accumulation and enhance pharmacopoeial constituents of S. miltiorrhiza, supporting the production of low-Cd, high-quality medicinal materials in Cd-contaminated farmland.<\/jats:p>","DOI":"10.3390\/plants15182858","type":"journal-article","created":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T11:05:53Z","timestamp":1789988753000},"page":"2858","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Screening of Rhizobacteria Capable of Modulating Cd Accumulation and Enhancing Pharmacopoeial Constituents in Salvia miltiorrhiza"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8502-9758","authenticated-orcid":false,"given":"Jinqiu","family":"Liao","sequence":"first","affiliation":[{"name":"College of Life Sciences, Sichuan Agricultural University, Ya\u2019an 625014, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"methodology","vocabulary":"credit"},{"role":"writing-original-draft","vocabulary":"credit"}]},{"given":"Tong","family":"Peng","sequence":"additional","affiliation":[{"name":"College of Life Sciences, Sichuan Agricultural University, Ya\u2019an 625014, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"data-curation","vocabulary":"credit"}]},{"given":"Zheng\u2019e","family":"Han","sequence":"additional","affiliation":[{"name":"College of Life Sciences, Sichuan Agricultural University, Ya\u2019an 625014, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"writing-original-draft","vocabulary":"credit"}]},{"given":"Kecen","family":"Pan","sequence":"additional","affiliation":[{"name":"College of Life Sciences, Sichuan Agricultural University, Ya\u2019an 625014, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"data-curation","vocabulary":"credit"}]},{"given":"Meishen","family":"Liu","sequence":"additional","affiliation":[{"name":"College of Life Sciences, Sichuan Agricultural University, Ya\u2019an 625014, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"data-curation","vocabulary":"credit"}]},{"given":"Li","family":"Zhang","sequence":"additional","affiliation":[{"name":"College of Science, Sichuan Agricultural University, Ya\u2019an 625014, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"data-curation","vocabulary":"credit"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1346-6235","authenticated-orcid":false,"given":"Ruiwu","family":"Yang","sequence":"additional","affiliation":[{"name":"College of Life Sciences, Sichuan Agricultural University, Ya\u2019an 625014, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"project-administration","vocabulary":"credit"},{"role":"funding-acquisition","vocabulary":"credit"}]}],"member":"1968","published-online":{"date-parts":[[2026,9,18]]},"reference":[{"key":"ref_1","first-page":"14","article-title":"Soil to plant transfer of cadmium","volume":"32","author":"Sterckeman","year":"2025","journal-title":"Oilseeds Fats Crops Lipids"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Yang, Y., Hassan, M.F., Ali, W., Zou, H., Liu, Z., and Ma, Y. (2025). Effects of cadmium pollution on human health: A narrative review. Atmosphere, 16.","DOI":"10.3390\/atmos16020225"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1038\/s43705-023-00213-z","article-title":"Metagenomic and machine learning-aided identification of biomarkers driving distinctive Cd accumulation features in the root-associated microbiome of two rice cultivars","volume":"3","author":"Cheng","year":"2023","journal-title":"ISME Commun."},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Zhang, K., Du, X., Li, X., Li, S., Liu, H., Bai, L., and Dai, J. (2025). Identification of peanut cultivars with low cadmium contents and their rhizosphere microbial characteristics in alkaline and acidic cadmium-contaminated fields. Sustainability, 17.","DOI":"10.3390\/su17020626"},{"key":"ref_5","first-page":"1520","article-title":"Effects of transplanting rhizosphere microorganisms from maize with high and low cadmium accumulation on maize growth and cadmium accumulation","volume":"52","author":"Liu","year":"2025","journal-title":"Bull. Microbiol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/j.soilbio.2009.11.024","article-title":"Plant growth-promoting bacteria in the rhizo- and endosphere of plants: Their role, colonization, mechanisms involved and prospects for utilization","volume":"42","author":"Compant","year":"2010","journal-title":"Soil Biol. Biochem."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1073\/pnas.1218984110","article-title":"Bacillus subtilis biofilm induction by plant polysaccharides","volume":"110","author":"Beauregard","year":"2013","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"fuad066","DOI":"10.1093\/femsre\/fuad066","article-title":"Root colonization by beneficial rhizobacteria","volume":"48","author":"Liu","year":"2024","journal-title":"FEMS Microbiol. Rev."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Farookhi, H., and Xia, X. (2024). Differential selection for translation efficiency shapes translation machineries in bacterial species. Microorganisms, 12.","DOI":"10.20944\/preprints202403.1437.v1"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"134134","DOI":"10.1016\/j.jhazmat.2024.134134","article-title":"Cadmium biosorption and mechanism investigation using two cadmium-tolerant microorganisms isolated from rhizosphere soil of rice","volume":"470","author":"Yan","year":"2024","journal-title":"J. Hazard. Mater."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"122792","DOI":"10.1016\/j.envpol.2023.122792","article-title":"Genotypic variation in grain cadmium concentration in wheat: Insights into soil pollution, agronomic characteristics, and rhizosphere microbial communities","volume":"340","author":"Zhang","year":"2024","journal-title":"Environ. Pollut."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"8707","DOI":"10.1007\/s11356-019-06957-3","article-title":"Isolation of urease-producing bacteria and their effects on reducing Cd and Pb accumulation in lettuce (Lactuca sativa L.)","volume":"27","author":"Wang","year":"2020","journal-title":"Environ. Sci. Pollut. Res."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.soilbio.2013.10.021","article-title":"Interaction of Cd-hyperaccumulator Solanum nigrum L. and functional endophyte Pseudomonas sp. Lk9 on soil heavy metals uptake","volume":"68","author":"Chen","year":"2014","journal-title":"Soil Biol. Biochem."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"6016","DOI":"10.1093\/jxb\/eraf290","article-title":"Cadmium-immobilizing bacteria utilize octanoic acid and two synthetic compounds to enhance nitrogen fixation in soybeans under cadmium stress","volume":"76","author":"Wang","year":"2025","journal-title":"J. Exp. Bot."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"9350","DOI":"10.1007\/s11356-017-8565-9","article-title":"The effects of endophytic bacterium SaMR12 on Sedum alfredii Hance metal ion uptake and the expression of three transporter family genes after cadmium exposure","volume":"24","author":"Pan","year":"2017","journal-title":"Environ. Sci. Pollut. Res."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.ecoenv.2019.02.074","article-title":"Endophytic bacteria isolated from Solanum nigrum L., alleviate cadmium (Cd) stress response by their antioxidant potentials, including SOD synthesis by sodA gene","volume":"174","author":"Ullah","year":"2019","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"19764","DOI":"10.1007\/s11356-020-08474-0","article-title":"Bacteria Sphingobium yanoikuyae Sy310 enhances accumulation capacity and tolerance of cadmium in Salix matsudana Koidz roots","volume":"27","author":"Zeng","year":"2020","journal-title":"Environ. Sci. Pollut. Res."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"128516","DOI":"10.1016\/j.biortech.2022.128516","article-title":"Microbial communities that drive the degradation of flax pectin and hemicellulose during dew retting with Bacillus licheniformis HDYM-04 and Bacillus subtilis ZC-01 addition","volume":"371","author":"Zhang","year":"2023","journal-title":"Bioresour. Technol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"35","DOI":"10.53388\/TMR20201027204","article-title":"Traditional Chinese medicine of Salvia miltiorrhiza Bunge: A review of phytochemistry, pharmacology and pharmacokinetics","volume":"6","author":"Nwafor","year":"2021","journal-title":"Tradit. Med. Res."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"135978","DOI":"10.1016\/j.chemosphere.2022.135978","article-title":"Identification of Salvia miltiorrhiza Bunge with high and low cadmium accumulation and insight into the mechanisms of cadmium accumulation","volume":"307","author":"Liao","year":"2022","journal-title":"Chemosphere"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"147782","DOI":"10.1016\/j.ijbiomac.2025.147782","article-title":"Dynamic remodeling of pectin and hemicellulose for contrastive cadmium accumulations with root cell walls in distinct Salvia miltiorrhiza ecotypes","volume":"329","author":"Liao","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1794","DOI":"10.1016\/j.chemosphere.2006.07.067","article-title":"Solubilization of zinc compounds by the diazotrophic, plant growth promoting bacterium Gluconacetobacter diazotrophicus","volume":"66","author":"Saravanan","year":"2007","journal-title":"Chemosphere"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"133876","DOI":"10.1016\/j.jhazmat.2024.133876","article-title":"The highly effective cadmium-resistant mechanism of Pseudomonas aeruginosa and the function of pyoverdine induced by cadmium","volume":"469","author":"Mei","year":"2024","journal-title":"J. Hazard. Mater."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"141828","DOI":"10.1016\/j.chemosphere.2024.141828","article-title":"Inhibitory effects of Pseudomonas sp. W112 on cadmium accumulation in wheat grains: Reduced the bioavailability in soil and enhanced the interception by plant organs","volume":"355","author":"Guo","year":"2024","journal-title":"Chemosphere"},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Liu, S., Huang, Y., Zheng, Q., Zhan, M., Hu, Z., Ji, H., Zhu, D., and Zhao, X. (2024). Cd-resistant plant growth-promoting rhizobacteria Bacillus siamensis R27 absorbed Cd and reduced Cd accumulation in Lettuce (Lactuca sativa L.). Microorganisms, 12.","DOI":"10.3390\/microorganisms12112321"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1007\/s11104-025-08075-1","article-title":"Pseudomonas sp. HYQ2 enhances cadmium phytoextraction by Phytolacca icosandra L. through interacting with other plant growth-promoting rhizobacteria","volume":"518","author":"Li","year":"2025","journal-title":"Plant Soil"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1111\/jam.14165","article-title":"The potential of cadmium ion-immobilized Rhizobium pusense KG2 to prevent soybean root from absorbing cadmium in cadmium-contaminated soil","volume":"126","author":"Li","year":"2019","journal-title":"J. Appl. Microbiol."},{"key":"ref_28","doi-asserted-by":"crossref","unstructured":"Mubeen, S., Ni, W., He, C., and Yang, Z. (2023). Agricultural strategies to reduce cadmium accumulation in crops for food safety. Agriculture, 13.","DOI":"10.3390\/agriculture13020471"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"3887","DOI":"10.1007\/s00253-019-09700-7","article-title":"Role of novel bacterial Raoultella sp. strain X13 in plant growth promotion and cadmium bioremediation in soil","volume":"103","author":"Xu","year":"2019","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"ref_30","doi-asserted-by":"crossref","unstructured":"Che\u021ban, F., Moraru, P.I., Rusu, T., \u0218imon, A., Dinca, L., and Murariu, G. (2025). From contamination to mitigation: Addressing cadmium pollution in agricultural soils. Agriculture, 15.","DOI":"10.3390\/agriculture15202179"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"141004","DOI":"10.1016\/j.jhazmat.2025.141004","article-title":"Divergent genomic characteristics and convergent metabolic phenotypes associated with Cd tolerance and soil Cd immobilization in multifunctional bacteria","volume":"502","author":"Wu","year":"2026","journal-title":"J. Hazard. Mater."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"131922","DOI":"10.1016\/j.jhazmat.2023.131922","article-title":"Inoculation of Escherichia coli enriched the key functional bacteria that intensified cadmium accumulation by halophyte Suaeda salsa in saline soils","volume":"458","author":"He","year":"2023","journal-title":"J. Hazard. Mater."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"143464","DOI":"10.1016\/j.chemosphere.2024.143464","article-title":"Inoculation of multi-metal-resistant Bacillus sp. to a hyperaccumulator plant Sedum alfredii for facilitating phytoextraction of heavy metals from contaminated soil","volume":"366","author":"Liu","year":"2024","journal-title":"Chemosphere"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1111\/pbi.12795","article-title":"Comparative transcriptome combined with morpho-physiological analyses revealed key factors for differential cadmium accumulation in two contrasting sweet sorghum genotypes","volume":"16","author":"Feng","year":"2017","journal-title":"Plant Biotechnol. J."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"123503","DOI":"10.1016\/j.envpol.2024.123503","article-title":"Methyl jasmonate regulation of pectin polysaccharides in Cosmos bipinnatus roots: A mechanistic insight into alleviating cadmium toxicity","volume":"345","author":"Fan","year":"2024","journal-title":"Environ. Pollut."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"112664","DOI":"10.1016\/j.plantsci.2025.112664","article-title":"Cell wall polysaccharides response to cadmium stress and transcriptome analysis in tomato (Solanum lycopersicum)","volume":"359","author":"Wang","year":"2025","journal-title":"Plant Sci."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"116597","DOI":"10.1016\/j.celrep.2025.116597","article-title":"Bacterial modification of the root cell wall facilitates rice aluminum resistance in acidic soils","volume":"44","author":"Zhang","year":"2025","journal-title":"Cell Rep."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"174503","DOI":"10.1016\/j.scitotenv.2024.174503","article-title":"Synergistic enhancement of plant growth and cadmium stress defense by Azospirillum brasilense and plant heme: Modulating the growth\u2013defense relationship","volume":"946","author":"Cui","year":"2024","journal-title":"Sci. Total Environ."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1134\/S0026261715050021","article-title":"Effect of Azospirillum lectins on the activity of proteolytic enzymes and their inhibitors in wheat seedling roots","volume":"84","author":"Nikitina","year":"2015","journal-title":"Microbiology"},{"key":"ref_40","doi-asserted-by":"crossref","unstructured":"Bai, X., Han, Y., and Han, L. (2024). Transcriptional alterations of peanut root during interaction with growth-promoting Tsukamurella tyrosinosolvens strain P9. PLoS ONE, 19.","DOI":"10.1371\/journal.pone.0298303"},{"key":"ref_41","doi-asserted-by":"crossref","unstructured":"Gamez, R.M., Rodr\u00edguez, F., Vidal, N.M., Ramirez, S., Alvarez, R.V., Landsman, D., and Mari\u00f1o-Ram\u00edrez, L. (2019). Banana (Musa acuminata) transcriptome profiling in response to rhizobacteria: Bacillus amyloliquefaciens Bs006 and Pseudomonas fluorescens Ps006. BMC Genom., 20.","DOI":"10.1186\/s12864-019-5763-5"},{"key":"ref_42","doi-asserted-by":"crossref","unstructured":"Chen, C., Tang, X., Liao, C., Huang, X., Zhang, M., Zhang, Y., Wang, P., Yang, S., Li, P., and Chen, C. (2025). Enhancing lignocellulose degradation and mycotoxin reduction in co-composting with bacterial inoculation. Microorganisms, 13.","DOI":"10.3390\/microorganisms13030677"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1186\/s13007-022-00872-4","article-title":"Development of a highly efficient virus-free regeneration system of Salvia miltiorrhiza from Sichuan using apical meristem as explants","volume":"18","author":"Yao","year":"2022","journal-title":"Plant Methods"},{"key":"ref_44","first-page":"85","article-title":"Stabilization characteristics of cadmium in some typical agricultural soils","volume":"36","author":"Li","year":"2017","journal-title":"J. Agric. Environ. Sci."},{"key":"ref_45","first-page":"175","article-title":"Effects of three endophytic bacteria in the roots of Salvia miltiorrhiza on host growth and medicinal quality","volume":"34","author":"Ma","year":"2025","journal-title":"Acta Prataculturae Sin."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"111261","DOI":"10.1016\/j.plaphy.2026.111261","article-title":"Spatio-temporal and chemical regulation of apoplastic barrier development confers low cadmium accumulation in Salvia miltiorrhiza","volume":"233","author":"Liao","year":"2026","journal-title":"Plant Physiol. Biochem."},{"key":"ref_47","doi-asserted-by":"crossref","unstructured":"He, C., Han, T., Liu, C., Sun, P., Liao, D., and Li, X. (2023). Deciphering the effects of genotype and climatic factors on the performance, active ingredients and rhizosphere soil properties of Salvia miltiorrhiza. Front. Plant Sci., 141.","DOI":"10.3389\/fpls.2023.1110860"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"132648","DOI":"10.1016\/j.jhazmat.2023.132648","article-title":"Root chemistry and microbe interactions contribute to metal(loid) tolerance of an aromatic plant\u2014Vetiver grass","volume":"461","author":"Li","year":"2024","journal-title":"J. Hazard. Mater."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"133851","DOI":"10.1016\/j.jhazmat.2024.133851","article-title":"Cadmium induced changes in rhizosphere microecology to enhance Cd intake by Ligusticum sinense cv. Chuanxiong","volume":"468","author":"Xie","year":"2024","journal-title":"J. Hazard. Mater."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"107336","DOI":"10.1016\/j.agee.2021.107336","article-title":"Microbial assembly and association network in watermelon rhizosphere after soil fumigation for Fusarium wilt control","volume":"312","author":"Ge","year":"2021","journal-title":"Agric. Ecosyst. Environ."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1186\/s40168-025-02154-2","article-title":"\u03b2-Elemonic acid mediated enrichment of Paenibacillus to help Salvia miltiorrhiza Bunge alleviate drought stress","volume":"13","author":"Jia","year":"2025","journal-title":"Microbiome"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1080\/03067319.2019.1669583","article-title":"Removal of cadmium (II) in the aqueous solutions by biosorption of Bacillus licheniformis isolated from soil in the area of Tigris River","volume":"101","author":"Baran","year":"2019","journal-title":"Int. J. Environ. Anal. Chem."},{"key":"ref_53","unstructured":"Chinese Pharmacopoeia Commission (2025). Pharmacopoeia of the People\u2019s Republic of China."}],"container-title":["Plants"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2223-7747\/15\/18\/2858\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T11:49:55Z","timestamp":1789991395000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2223-7747\/15\/18\/2858"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,18]]},"references-count":53,"journal-issue":{"issue":"18","published-online":{"date-parts":[[2026,9]]}},"alternative-id":["plants15182858"],"URL":"https:\/\/doi.org\/10.3390\/plants15182858","relation":{},"ISSN":["2223-7747"],"issn-type":[{"value":"2223-7747","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,18]]}}}