{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T05:35:35Z","timestamp":1790660135722,"version":"4.1.0"},"reference-count":25,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2020,2,4]],"date-time":"2020-02-04T00:00:00Z","timestamp":1580774400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["17H02080"],"award-info":[{"award-number":["17H02080"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"name":"The UC Irvine Institute for Clinical and Translational Science","award":["UL1 TR000141"],"award-info":[{"award-number":["UL1 TR000141"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Polymers"],"abstract":"<jats:p>Electrospinning and post-spun conformations of hydrophobic poly(\u03b1-amino acid)s are described in this study. The poly(\u03b1-amino acid)s, poly(Gly), poly(l-Ala), poly(l-Val), and poly(l-Leu) were synthesized via corresponding N-carboxy-\u03b1-amino acid anhydrides. The average molecular weight and degree of polymerization of these polymers were determined by N-terminus labeling using 2,4-dinitrofluorobenzene and by viscometry in the case of poly(Gly). These poly(\u03b1-amino acid)s were electrospun from trifluoroacetic acid or trifluoroacetic acid\/dichloromethane solutions. The FT-IR spectroscopy and wide-angle X-ray diffraction indicated that the electrospun poly(l-Ala) and poly(l-Leu) fibers predominantly adopts \u03b1-helical structure, whereas poly(l-Val) and poly(Gly) fibers exhibited mainly \u03b2-strand and random coil structures, respectively.<\/jats:p>","DOI":"10.3390\/polym12020327","type":"journal-article","created":{"date-parts":[[2020,2,6]],"date-time":"2020-02-06T02:59:18Z","timestamp":1580957958000},"page":"327","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Electrospinning and Post-Spun Chain Conformations of Synthetic, Hydrophobic Poly(\u03b1-amino acid)s"],"prefix":"10.3390","volume":"12","author":[{"given":"Kesavan","family":"Devarayan","sequence":"first","affiliation":[{"name":"Department of Basic Sciences, College of Fisheries Engineering, Tamil Nadu J. Jayalalithaa Fisheries University, Vettar River View Campus, Nagapattinam 611 002, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Souta","family":"Nakagami","sequence":"additional","affiliation":[{"name":"Division of Synthetic Polymers, Institute of High Polymer Research, Faculty of Textile Science and Technology, Shinshu University, Tokida 3-15-1, Ueda 386-8567, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuichi","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, University of California, Irvine, 200S Manchester St., Suite 210, Orange, CA 92868, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ichiro","family":"Yuki","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, University of California, Irvine, 200S Manchester St., Suite 210, Orange, CA 92868, USA"},{"name":"Department of Neurosurgery, The Jikei Univeristy Hospital, 3 Chome-25-8 Nishishinbashi, Minato City, Tokyo 105-8461, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5199-092X","authenticated-orcid":false,"given":"Kousaku","family":"Ohkawa","sequence":"additional","affiliation":[{"name":"Division of Synthetic Polymers, Institute of High Polymer Research, Faculty of Textile Science and Technology, Shinshu University, Tokida 3-15-1, Ueda 386-8567, Japan"},{"name":"Department of Neurological Surgery, University of California, Irvine, 200S Manchester St., Suite 210, Orange, CA 92868, USA"},{"name":"Division of Biological and Medical Fibers, Institute for Fiber Engineering, Interdisciplinary Cluster for Cutting Edge Research, Shinshu University, Tokida 3-15-1, Ueda 386-8567, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,2,4]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2223","DOI":"10.1016\/S0266-3538(03)00178-7","article-title":"On polymer nanofibers by electrospinning and their applications in nanocomposites\u2014A review","volume":"63","author":"Huang","year":"2003","journal-title":"Compos. 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