{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T22:59:35Z","timestamp":1782514775676,"version":"3.54.5"},"reference-count":35,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2020,8,29]],"date-time":"2020-08-29T00:00:00Z","timestamp":1598659200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","award":["COST Action CA18125 \u201cAdvanced Engineering and Research of aeroGels for Environment and Life Sciences\u201d (AERoGELS)"],"award-info":[{"award-number":["COST Action CA18125 \u201cAdvanced Engineering and Research of aeroGels for Environment and Life Sciences\u201d (AERoGELS)"]}],"id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Polymers"],"abstract":"<jats:p>The kinetics of the supercritical adsorption process was experimentally studied by the example of \u201dibuprofen-silica aerogel\u201d composition obtainment at various parameters: Pressure 120\u2013200 bar and temperature 40\u201360 \u00b0C. Computational Fluid Dynamics (CFD) model of the supercritical adsorption process in a high-pressure apparatus based on the provisions of continuum mechanics is proposed. Using supercritical adsorption process kinetics experimental data, the dependences of the effective diffusion coefficient of active substance in the aerogel, and the maximum amount of the adsorbed active substance into the aerogel on temperature and pressure are revealed. Adequacy of the proposed model is confirmed. The proposed mathematical model allows predicting the behavior of system (fields of velocity, temperature, pressure, composition, density, etc.) at each point of the studied medium. It makes possible to predict mass transport rate of the active substance inside the porous body depending on the geometry of the apparatus, structure of flow, temperature, and pressure.<\/jats:p>","DOI":"10.3390\/polym12091957","type":"journal-article","created":{"date-parts":[[2020,8,30]],"date-time":"2020-08-30T06:06:22Z","timestamp":1598767582000},"page":"1957","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Experimental Investigation and CFD Modeling of Supercritical Adsorption Process"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6765-7563","authenticated-orcid":false,"given":"Artem","family":"Lebedev","sequence":"first","affiliation":[{"name":"International Center for Transfer of Pharmaceutical and Biotechnology, Mendeleev University of Chemical Technology of Russia, Moscow 125047, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8709-4139","authenticated-orcid":false,"given":"Daria","family":"Lovskaya","sequence":"additional","affiliation":[{"name":"International Center for Transfer of Pharmaceutical and Biotechnology, Mendeleev University of Chemical Technology of Russia, Moscow 125047, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalia","family":"Menshutina","sequence":"additional","affiliation":[{"name":"International Center for Transfer of Pharmaceutical and Biotechnology, Mendeleev University of Chemical Technology of Russia, Moscow 125047, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,8,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"104711","DOI":"10.1016\/j.supflu.2019.104711","article-title":"Supercritical impregnation of mesoglycan into calcium alginate aerogel for wound healing","volume":"157","author":"Franco","year":"2020","journal-title":"J. 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