{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T05:45:04Z","timestamp":1787377504712,"version":"build-2736575974"},"reference-count":67,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2021,6,11]],"date-time":"2021-06-11T00:00:00Z","timestamp":1623369600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004281","name":"Narodowe Centrum Nauki","doi-asserted-by":"publisher","award":["SONATA 2016\/23\/D\/ST5\/01306"],"award-info":[{"award-number":["SONATA 2016\/23\/D\/ST5\/01306"]}],"id":[{"id":"10.13039\/501100004281","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004281","name":"Narodowe Centrum Nauki","doi-asserted-by":"publisher","award":["OPUS 2019\/35\/B\/ST5\/00995"],"award-info":[{"award-number":["OPUS 2019\/35\/B\/ST5\/00995"]}],"id":[{"id":"10.13039\/501100004281","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007835","name":"Politechnika \u015al\u0105ska","doi-asserted-by":"publisher","award":["04\/040\/BK_21\/0145"],"award-info":[{"award-number":["04\/040\/BK_21\/0145"]}],"id":[{"id":"10.13039\/501100007835","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007835","name":"Politechnika \u015al\u0105ska","doi-asserted-by":"publisher","award":["04\/040\/RGJ21\/0147"],"award-info":[{"award-number":["04\/040\/RGJ21\/0147"]}],"id":[{"id":"10.13039\/501100007835","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Polymers"],"abstract":"<jats:p>The aspiration to interact living cells with electronics challenges researchers to develop materials working at the interface of these two distinct environments. A successful interfacing coating should exhibit both biocompatibility and desired functionality of a bio-integrated device. Taking into account biodiversity, the tissue interface should be fine-tuned to the specific requirements of the bioelectronic systems. In this study, we pointed to electrochemical doping of conducting polymers as a strategy enabling the efficient manufacturing of interfacing platforms, in which features could be easily adjusted. Consequently, we fabricated conducting films based on a poly(3,4-ethylenedioxythiophene) (PEDOT) matrix, with properties modulated through doping with selected ions: PSS\u2212 (poly(styrene sulfonate)), ClO4\u2212 (perchlorate), and PF6\u2212 (hexafluorophosphate). Striving to extend the knowledge on the relationships governing the dopant effect on PEDOT films, the samples were characterized in terms of their chemical, morphological, and electrochemical properties. To investigate the impact of the materials on attachment and growth of cells, rat neuroblastoma B35 cells were cultured on their surface and analyzed using scanning electron microscopy and biological assays. Eventually, it was shown that through the choice of a dopant and doping conditions, PEDOT-based materials can be efficiently tuned with diversified physicochemical properties. Therefore, our results proved electrochemical doping of PEDOT as a valuable strategy facilitating the development of promising tissue interfacing materials with characteristics tailored as required.<\/jats:p>","DOI":"10.3390\/polym13121948","type":"journal-article","created":{"date-parts":[[2021,6,14]],"date-time":"2021-06-14T22:25:46Z","timestamp":1623709546000},"page":"1948","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Dopant-Dependent Electrical and Biological Functionality of PEDOT in Bioelectronics"],"prefix":"10.3390","volume":"13","author":[{"given":"Ma\u0142gorzata","family":"Skorupa","sequence":"first","affiliation":[{"name":"Department of Physical Chemistry and Technology of Polymers, Silesian University of Technology, 44-100 Gliwice, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daria","family":"Wi\u0119c\u0142awska","sequence":"additional","affiliation":[{"name":"Department of Physical Chemistry and Technology of Polymers, Silesian University of Technology, 44-100 Gliwice, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4090-2127","authenticated-orcid":false,"given":"Dominika","family":"Czerwi\u0144ska-G\u0142\u00f3wka","sequence":"additional","affiliation":[{"name":"Department of Physical Chemistry and Technology of Polymers, Silesian University of Technology, 44-100 Gliwice, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6263-9585","authenticated-orcid":false,"given":"Magdalena","family":"Skonieczna","sequence":"additional","affiliation":[{"name":"Biotechnology Centre, Silesian University of Technology, 44-100 Gliwice, Poland"},{"name":"Department of Systems Biology and Engineering, Faculty of Automatic Control, Electronics and Computer Science, Silesian University of Technology, 44-100 Gliwice, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0503-0906","authenticated-orcid":false,"given":"Katarzyna","family":"Krukiewicz","sequence":"additional","affiliation":[{"name":"Department of Physical Chemistry and Technology of Polymers, Silesian University of Technology, 44-100 Gliwice, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,6,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"4811","DOI":"10.1039\/C9TB01028A","article-title":"PEDOT:PSS interfaces stabilised using a PEGylated crosslinker yield improved conductivity and biocompatibility","volume":"7","author":"Solazzo","year":"2019","journal-title":"J. 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