{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T02:32:15Z","timestamp":1760236335677,"version":"build-2065373602"},"reference-count":130,"publisher":"MDPI AG","issue":"22","license":[{"start":{"date-parts":[[2021,11,20]],"date-time":"2021-11-20T00:00:00Z","timestamp":1637366400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100007446","name":"King Khalid University","doi-asserted-by":"publisher","award":["(RGP.1\/99\/42)"],"award-info":[{"award-number":["(RGP.1\/99\/42)"]}],"id":[{"id":"10.13039\/501100007446","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Polymers"],"abstract":"<jats:p>The lung is a vital organ that houses the alveoli, which is where gas exchange takes place. The COVID-19 illness attacks lung cells directly, creating significant inflammation and resulting in their inability to function. To return to the nature of their job, it may be essential to rejuvenate the afflicted lung cells. This is difficult because lung cells need a long time to rebuild and resume their function. Biopolymeric particles are the most effective means to transfer developing treatments to airway epithelial cells and then regenerate infected lung cells, which is one of the most significant symptoms connected with COVID-19. Delivering biocompatible and degradable natural biological materials, chemotherapeutic drugs, vaccines, proteins, antibodies, nucleic acids, and diagnostic agents are all examples of these molecules\u2018 usage. Furthermore, they are created by using several structural components, which allows them to effectively connect with these cells. We highlight their most recent uses in lung tissue regeneration in this review. These particles are classified into three groups: biopolymeric nanoparticles, biopolymeric stem cell materials, and biopolymeric scaffolds. The techniques and processes for regenerating lung tissue will be thoroughly explored.<\/jats:p>","DOI":"10.3390\/polym13224011","type":"journal-article","created":{"date-parts":[[2021,11,21]],"date-time":"2021-11-21T21:00:50Z","timestamp":1637528450000},"page":"4011","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The Potential Contribution of Biopolymeric Particles in Lung Tissue Regeneration of COVID-19 Patients"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3141-2900","authenticated-orcid":false,"given":"Mohamed","family":"Abbas","sequence":"first","affiliation":[{"name":"Electrical Engineering Department, College of Engineering, King Khalid University, Abha 61421, Saudi Arabia"},{"name":"Computers and Communications Department, College of Engineering, Delta University for Science and Technology, Gamasa 35712, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammed S.","family":"Alqahtani","sequence":"additional","affiliation":[{"name":"Radiological Sciences Department, College of Applied Medical Sciences, King Khalid University, Abha 61421, Saudi Arabia"},{"name":"BioImaging Unit, Space Research Centre, Michael Atiyah Building, University of Leicester, Leicester LE1 7RH, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hussain M.","family":"Almohiy","sequence":"additional","affiliation":[{"name":"Radiological Sciences Department, College of Applied Medical Sciences, King Khalid University, Abha 61421, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1494-0303","authenticated-orcid":false,"given":"Fawaz F.","family":"Alqahtani","sequence":"additional","affiliation":[{"name":"Department of Radiological Sciences, College of Applied Medical Sciences, Najran University, Najran 1988, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roaa","family":"Alhifzi","sequence":"additional","affiliation":[{"name":"Radiological Sciences Department, College of Applied Medical Sciences, King Khalid University, Abha 61421, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2098-6925","authenticated-orcid":false,"given":"Layal K.","family":"Jambi","sequence":"additional","affiliation":[{"name":"Radiological Sciences Department, College of Applied Medical Sciences, King Saud University, P.O. Box 10219, Riyadh 11433, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,11,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"102435","DOI":"10.1016\/j.jddst.2021.102435","article-title":"Recent updates in COVID-19 with emphasis on inhalation therapeutics: Nanostructured and targeting systems","volume":"63","author":"Abdellatif","year":"2021","journal-title":"J. Drug Deliv. Sci. Technol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"636222","DOI":"10.3389\/fimmu.2021.636222","article-title":"Proteomic Characterization, Biodistribution, and Functional Studies of Immune-Therapeutic Exosomes: Implications for Inflammatory Lung Diseases","volume":"12","author":"Elashiry","year":"2021","journal-title":"Front. 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