{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T02:21:22Z","timestamp":1791339682009,"version":"4.3.1"},"reference-count":40,"publisher":"MDPI AG","issue":"24","license":[{"start":{"date-parts":[[2021,12,8]],"date-time":"2021-12-08T00:00:00Z","timestamp":1638921600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Government of Extremadura","award":["GR18153"],"award-info":[{"award-number":["GR18153"]}]},{"name":"Ministerio de Ciencia e Innovaci\u00f3n del Gobierno de Espa\u00f1a, Agencia Espa\u00f1ola de Investigaci\u00f3n","award":["RTI2018-096862-B-I00"],"award-info":[{"award-number":["RTI2018-096862-B-I00"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Polymers"],"abstract":"<jats:p>The study of the surface properties of materials is key in determining whether the material will be suitable for medical purposes. One of these properties is hydrophobicity, which is important when assessing its behavior against bacterial adhesion. In this work, we have studied the influence of the solvent (chloroform, acetone, and tetrahydrofuran) and the substrate (glass, PTFE, silicone, and Ti6Al4V) on which polylactic acid is deposited in solution to manufacture films by solvent-casting. Thus, it has been found that there are no significant differences in hydrophobicity and surface tension among the solvents evaluated, but there are significant differences with respect to the substrates: PLA films casted on silicone are hydrophobic, while those casted on the rest of the substrates are hydrophilic. This is related to the fact that the silicone interacts with the polymer modifying its spatial arrangement, exposing its methyl groups towards the interface with the air. In this way, it has been shown that, when manufacturing PLA films, it is important to choose the right surface on which to deposit them, depending on their desired function.<\/jats:p>","DOI":"10.3390\/polym13244289","type":"journal-article","created":{"date-parts":[[2021,12,8]],"date-time":"2021-12-08T23:30:00Z","timestamp":1639006200000},"page":"4289","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Influence of Solvent and Substrate on Hydrophobicity of PLA Films"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0780-2466","authenticated-orcid":false,"given":"Ver\u00f3nica","family":"Luque-Agudo","sequence":"first","affiliation":[{"name":"Department of Applied Physics, University of Extremadura, 06006 Badajoz, Spain"},{"name":"Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), 06006 Badajoz, Spain"},{"name":"University Institute of Extremadura Sanity Research (INUBE), 06006 Badajoz, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amparo M.","family":"Gallardo-Moreno","sequence":"additional","affiliation":[{"name":"Department of Applied Physics, University of Extremadura, 06006 Badajoz, Spain"},{"name":"Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), 06006 Badajoz, Spain"},{"name":"University Institute of Extremadura Sanity Research (INUBE), 06006 Badajoz, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Luisa","family":"Gonz\u00e1lez-Mart\u00edn","sequence":"additional","affiliation":[{"name":"Department of Applied Physics, University of Extremadura, 06006 Badajoz, Spain"},{"name":"Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), 06006 Badajoz, Spain"},{"name":"University Institute of Extremadura Sanity Research (INUBE), 06006 Badajoz, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,12,8]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1612","DOI":"10.1111\/jam.14290","article-title":"Polylactic acid: Synthesis and biomedical applications","volume":"127","author":"Singhvi","year":"2019","journal-title":"J. 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