{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T11:37:30Z","timestamp":1777635450299,"version":"3.51.4"},"reference-count":52,"publisher":"MDPI AG","issue":"22","license":[{"start":{"date-parts":[[2022,11,21]],"date-time":"2022-11-21T00:00:00Z","timestamp":1668988800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003336","name":"Bulgarian National Science Fund","doi-asserted-by":"publisher","award":["KP- 06-N39\/13\/2019"],"award-info":[{"award-number":["KP- 06-N39\/13\/2019"]}],"id":[{"id":"10.13039\/501100003336","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Polymers"],"abstract":"<jats:p>The conventional approach for preparation of core-sheath fibers is coaxial electrospinning. Single-spinneret electrospinning of emulsions is a much less common method to obtain core-sheath fibers. Core-sheath structure may be generated by electrospinning of homogeneous blend solutions; however, reports on such cases are still scarce. Herein, the preparation of nanofibrous composites from poly(ethylene oxide) (PEO), poly(L-lactide) (PLA) and beeswax (BW) by single-spinneret electrospinning of their homogeneous blend solutions in chloroform is reported. The produced fibers had core\/double-sheath structure with a PEO core, PLA inner sheath and BW outer sheath. This original fiber structure was evidenced by transmission electron microscopy, selective extraction of BW or PEO, and X-ray photoelectron spectroscopy. The PLA\/BW double sheath led to hydrophobicity of the PEO\/PLA\/BW mats. The tensile tests revealed that PEO\/PLA\/BW mats had substantially improved mechanical behavior as compared to PEO, PLA and PEO\/BW mats. PEO\/PLA\/BW mats can be used as drug carriers as evidenced by the one-pot incorporation of the model drug 5-nitro-8-hydroxyquinoline (NQ) into the fibrous materials. Microbiological tests showed that PEO\/PLA\/BW\/NQ had antimicrobial activity. Therefore, the new materials are promising for wound healing applications.<\/jats:p>","DOI":"10.3390\/polym14225036","type":"journal-article","created":{"date-parts":[[2022,11,22]],"date-time":"2022-11-22T03:13:41Z","timestamp":1669086821000},"page":"5036","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Core\/Double-Sheath Composite Fibers from Poly(ethylene oxide), Poly(L-lactide) and Beeswax by Single-Spinneret Electrospinning"],"prefix":"10.3390","volume":"14","author":[{"given":"Selin","family":"Kyuchyuk","sequence":"first","affiliation":[{"name":"Laboratory of Bioactive Polymers, Institute of Polymers, Bulgarian Academy of Sciences, Acad. G. Bonchev St., Bl. 103A, BG-1113 Sofia, Bulgaria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7294-9501","authenticated-orcid":false,"given":"Dilyana","family":"Paneva","sequence":"additional","affiliation":[{"name":"Laboratory of Bioactive Polymers, Institute of Polymers, Bulgarian Academy of Sciences, Acad. G. Bonchev St., Bl. 103A, BG-1113 Sofia, Bulgaria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8283-5340","authenticated-orcid":false,"given":"Nevena","family":"Manolova","sequence":"additional","affiliation":[{"name":"Laboratory of Bioactive Polymers, Institute of Polymers, Bulgarian Academy of Sciences, Acad. G. Bonchev St., Bl. 103A, BG-1113 Sofia, Bulgaria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3965-3450","authenticated-orcid":false,"given":"Iliya","family":"Rashkov","sequence":"additional","affiliation":[{"name":"Laboratory of Bioactive Polymers, Institute of Polymers, Bulgarian Academy of Sciences, Acad. G. Bonchev St., Bl. 103A, BG-1113 Sofia, Bulgaria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8785-3190","authenticated-orcid":false,"given":"Daniela","family":"Karashanova","sequence":"additional","affiliation":[{"name":"Institute of Optical Materials and Technologies, Bulgarian Academy of Sciences, Akad. G. Bonchev St., Bl. 109, BG-1113 Sofia, Bulgaria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadya","family":"Markova","sequence":"additional","affiliation":[{"name":"Institute of Microbiology, Bulgarian Academy of Sciences, Akad. G. Bonchev St., Bl. 26, BG-1113 Sofia, Bulgaria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,11,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1039\/b415094e","article-title":"Electrospinning of nanofibers with core-sheath, hollow, or porous structures","volume":"15","author":"McCann","year":"2005","journal-title":"J. Mater. Chem."},{"key":"ref_2","unstructured":"Chang, W.N. (2009). Novel chitosan-containing micro- and nanofibrous materials by electrospinning: Preparation and biomedical application. Nanofibers: Fabrication, Performance, and Applications, Science Publishers, Inc.. 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